CS91292A3 - Process for stereoisomeric enriching of2-amino-3-hydroxy-3-phenylpropionic acids - Google Patents

Process for stereoisomeric enriching of2-amino-3-hydroxy-3-phenylpropionic acids

Info

Publication number
CS91292A3
CS91292A3 CS92912A CS91292A CS91292A3 CS 91292 A3 CS91292 A3 CS 91292A3 CS 92912 A CS92912 A CS 92912A CS 91292 A CS91292 A CS 91292A CS 91292 A3 CS91292 A3 CS 91292A3
Authority
CS
Czechoslovakia
Prior art keywords
amino
hydroxy
threo
stereoisomeric
enriching
Prior art date
Application number
CS92912A
Other languages
English (en)
Inventor
Andrew L Zeitlin
Muppala S Raju
David I Stirling
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27418304&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CS91292(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of CS91292A3 publication Critical patent/CS91292A3/cs
Publication of CZ289218B6 publication Critical patent/CZ289218B6/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00Preparation of sulfones; Preparation of sulfoxides
    • C07C315/06Separation; Purification; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26Separation; Purification; Stabilisation; Use of additives
    • C07C319/28Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P11/00Preparation of sulfur-containing organic compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/24Preparation of oxygen-containing organic compounds containing a carbonyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/829Alcaligenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CS1992912A 1991-03-27 1992-03-26 Způsob enantiomerního obohacování směsi D- a L-threo-2-amino-3-hydroxy-3-fenylpropionových kyselin CZ289218B6 (cs)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67610291A 1991-03-27 1991-03-27
US68930091A 1991-04-22 1991-04-22
US07/844,724 US5346828A (en) 1991-03-27 1992-03-02 Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenylpropionic acids using d-threonine aldolase

Publications (2)

Publication Number Publication Date
CS91292A3 true CS91292A3 (en) 1992-12-16
CZ289218B6 CZ289218B6 (cs) 2001-12-12

Family

ID=27418304

Country Status (17)

Country Link
US (1) US5346828A (cs)
EP (1) EP0507153B1 (cs)
JP (1) JP3142627B2 (cs)
KR (1) KR100250513B1 (cs)
AT (1) ATE155175T1 (cs)
AU (1) AU645895B2 (cs)
CA (1) CA2064349C (cs)
CZ (1) CZ289218B6 (cs)
DE (1) DE69220701T2 (cs)
DK (1) DK0507153T3 (cs)
ES (1) ES2106101T3 (cs)
GR (1) GR3024971T3 (cs)
HU (1) HU214305B (cs)
IE (1) IE920866A1 (cs)
IL (1) IL101268A (cs)
NZ (1) NZ242040A (cs)
SK (1) SK282932B6 (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW397866B (en) 1993-07-14 2000-07-11 Bristol Myers Squibb Co Enzymatic processes for the resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes
EP0734453A1 (en) * 1993-12-17 1996-10-02 Dsm N.V. Phenylserine amides and the preparation of phenylserines/phenylserine amides
US7172885B2 (en) * 2004-12-10 2007-02-06 Cambrex North Brunswick, Inc. Thermostable omega-transaminases
EP1882737B1 (en) * 2005-05-20 2011-09-14 Ajinomoto Co., Inc. Process for production of l-serine derivative and enzyme used in the process
US7518017B2 (en) 2006-02-17 2009-04-14 Idexx Laboratories Fenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds
KR100758512B1 (ko) 2006-07-20 2007-09-14 엔자이텍 주식회사 효소적 방법에 의한 광학활성3-히드록시-3-페닐프로피온산과 광학활성3-아실옥시-3-페닐프로피온산의 제조 방법
HUE052297T2 (hu) 2009-01-08 2021-04-28 Codexis Inc Transzamináz polipeptidek
JP5707344B2 (ja) 2009-02-26 2015-04-30 コデクシス, インコーポレイテッド トランスアミナーゼ生体触媒
WO2011005477A1 (en) 2009-06-22 2011-01-13 Codexis, Inc. Transaminase reactions
HUE038434T2 (hu) 2010-06-17 2018-10-29 Codexis Inc Biokatalizátorok és módszerek (S)-3(1-aminoetil)-fenol szintéziséhez
EP2606139B1 (en) 2010-08-16 2015-07-15 Codexis, Inc. Biocatalysts and methods for the synthesis of (1r,2r)-2-(3,4-dimethoxyphenethoxy)cyclohexanamine
CN101941927B (zh) * 2010-09-28 2012-10-03 湖北美天生物科技有限公司 氟苯尼考中间体(1r,2r)-2-氨基-1–(4-(甲砜基)苯基)-1,3-丙二醇的合成方法
CN115611785B (zh) * 2022-12-19 2023-03-14 天津工微生物科技有限公司 (2r,3s)-2-氨基-3-羟基-3-(4-(甲基磺酰基)苯基)丙酸的纯化方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3733352A (en) * 1969-07-29 1973-05-15 Sumitomo Chemical Co Preparation of d-threo-1-p-methyl-sulfonylphenyl-2-dichloro-acet-amidopropane-1,3-diol
US3871958A (en) * 1972-03-04 1975-03-18 Ajinomoto Kk Biological method of producing serine and serinol derivatives
FR2378746A1 (fr) 1977-01-28 1978-08-25 Synthelabo Derives d'acides a-amines
US4235892A (en) * 1979-02-05 1980-11-25 Schering Corporation, Patent Dept. 1-Aryl-2-acylamido-3-fluoro-1-propanols, methods for their use as antibacterial agents and compositions useful therefor
US4492757A (en) * 1981-12-28 1985-01-08 Denki Kagaku Kogyo Kabushiki Kaisha Process for preparing L-threonine
US4582918A (en) * 1984-09-19 1986-04-15 Schering Corporation Preparation of intermediates for (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols
US4677214A (en) * 1984-09-19 1987-06-30 Schering Corporation Intermediates for preparation of (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols
DE3543021A1 (de) * 1985-12-05 1987-06-11 Boehringer Mannheim Gmbh Verbesserte verfahren zur herstellung von d-threo-1-(p-methylsulfonylphenyl) -2-dichloracetamido-propandiol-1,3-(thiamphenicol) sowie verwendung geeigneter zwischenprodukte
KR920701469A (ko) * 1989-05-15 1992-08-11 스테이너 브이. 캔스태드 향균성 화합물 및 이의 중간물질의 제조방법
AU6052090A (en) * 1989-07-07 1991-02-06 Schering Corporation Process for producing antibacterial intermediates via enzyme hydrolysis of racemic substrates

Also Published As

Publication number Publication date
HU9201041D0 (en) 1992-06-29
AU645895B2 (en) 1994-01-27
ATE155175T1 (de) 1997-07-15
HU214305B (hu) 1998-03-02
CZ289218B6 (cs) 2001-12-12
KR920018012A (ko) 1992-10-21
JP3142627B2 (ja) 2001-03-07
JPH06125790A (ja) 1994-05-10
EP0507153A3 (en) 1993-12-15
CA2064349A1 (en) 1992-09-28
KR100250513B1 (ko) 2000-04-01
US5346828A (en) 1994-09-13
AU1310692A (en) 1992-10-01
DK0507153T3 (da) 1997-12-22
SK282932B6 (sk) 2003-01-09
ES2106101T3 (es) 1997-11-01
CA2064349C (en) 2003-11-25
IL101268A (en) 1997-02-18
EP0507153B1 (en) 1997-07-09
GR3024971T3 (en) 1998-01-30
DE69220701T2 (de) 1997-11-06
IL101268A0 (en) 1992-11-15
HUT62261A (en) 1993-04-28
DE69220701D1 (de) 1997-08-14
NZ242040A (en) 1993-06-25
IE920866A1 (en) 1992-10-07
EP0507153A2 (en) 1992-10-07

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Legal Events

Date Code Title Description
PD00 Pending as of 2000-06-30 in czech republic
MK4A Patent expired

Effective date: 20120326