CS902588A2 - Method of 2-aminotetrahydroisoquinoline derivatives production - Google Patents
Method of 2-aminotetrahydroisoquinoline derivatives productionInfo
- Publication number
- CS902588A2 CS902588A2 CS889025A CS902588A CS902588A2 CS 902588 A2 CS902588 A2 CS 902588A2 CS 889025 A CS889025 A CS 889025A CS 902588 A CS902588 A CS 902588A CS 902588 A2 CS902588 A2 CS 902588A2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- aminotetrahydroisoquinoline
- production
- derivatives production
- denote hydrogen
- hydrogen
- Prior art date
Links
- LWEUOWQIECZGAW-UHFFFAOYSA-N 3,4,4a,5-tetrahydro-1h-isoquinolin-2-amine Chemical class C1C=CC=C2CN(N)CCC21 LWEUOWQIECZGAW-UHFFFAOYSA-N 0.000 title 1
- 239000001257 hydrogen Substances 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- IYANYSZUKHQLKL-UHFFFAOYSA-N 3,4-dihydro-1h-isoquinolin-2-amine Chemical class C1=CC=C2CN(N)CCC2=C1 IYANYSZUKHQLKL-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000894 saliuretic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/08—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with a hetero atom directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU876132A HU198458B (en) | 1987-12-30 | 1987-12-30 | Process for producing 2-aminoisoquinoline derivatives and pharmaceutical compositions comprising these compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS902588A2 true CS902588A2 (en) | 1990-09-12 |
| CS274495B2 CS274495B2 (en) | 1991-04-11 |
Family
ID=10971251
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS902588A CS274495B2 (en) | 1987-12-30 | 1988-12-29 | Method of 2-aminotetrahydroisoquinoline derivatives production |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4940716A (cs) |
| EP (1) | EP0324184B1 (cs) |
| JP (1) | JPH01213266A (cs) |
| CN (1) | CN1022917C (cs) |
| AT (1) | ATE112268T1 (cs) |
| AU (1) | AU635463B2 (cs) |
| CA (1) | CA1329209C (cs) |
| CS (1) | CS274495B2 (cs) |
| DD (1) | DD283382A5 (cs) |
| DE (1) | DE3851697D1 (cs) |
| ES (1) | ES2059485T3 (cs) |
| FI (1) | FI90536C (cs) |
| HR (1) | HRP920564A2 (cs) |
| HU (1) | HU198458B (cs) |
| IE (1) | IE883879L (cs) |
| IL (1) | IL88639A (cs) |
| NO (1) | NO176177C (cs) |
| NZ (1) | NZ227416A (cs) |
| PH (1) | PH25608A (cs) |
| PL (1) | PL155977B1 (cs) |
| PT (1) | PT89356B (cs) |
| SU (2) | SU1676444A3 (cs) |
| YU (1) | YU46720B (cs) |
| ZA (1) | ZA889285B (cs) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102005002130A1 (de) | 2005-01-17 | 2006-07-27 | Sanofi-Aventis Deutschland Gmbh | Substituierte N-Aminomethylensulfonamide, ihre Herstellung und Verwendung als Arzneimittel |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3037984A (en) * | 1960-01-27 | 1962-06-05 | Lakeside Lab Inc | Derivatives of n-amino-1, 2, 3, 4-tetrahydroisoquinoline |
| AU600992B2 (en) * | 1986-10-28 | 1990-08-30 | Smith Kline & French Laboratories Limited | Tetrahydroisoquinolin-2-yl derivatives of carboxylic acids |
-
1987
- 1987-12-30 HU HU876132A patent/HU198458B/hu not_active IP Right Cessation
-
1988
- 1988-12-09 IL IL88639A patent/IL88639A/xx not_active IP Right Cessation
- 1988-12-12 ZA ZA889285A patent/ZA889285B/xx unknown
- 1988-12-20 NZ NZ227416A patent/NZ227416A/en unknown
- 1988-12-22 CA CA000586780A patent/CA1329209C/en not_active Expired - Fee Related
- 1988-12-27 YU YU236088A patent/YU46720B/sh unknown
- 1988-12-28 JP JP63335678A patent/JPH01213266A/ja active Pending
- 1988-12-28 PT PT89356A patent/PT89356B/pt not_active IP Right Cessation
- 1988-12-28 PH PH37990A patent/PH25608A/en unknown
- 1988-12-29 US US07/295,920 patent/US4940716A/en not_active Expired - Fee Related
- 1988-12-29 CN CN88105622A patent/CN1022917C/zh not_active Expired - Fee Related
- 1988-12-29 CS CS902588A patent/CS274495B2/cs unknown
- 1988-12-29 NO NO885811A patent/NO176177C/no unknown
- 1988-12-29 IE IE883879A patent/IE883879L/xx unknown
- 1988-12-29 DD DD88324403A patent/DD283382A5/de not_active IP Right Cessation
- 1988-12-30 DE DE3851697T patent/DE3851697D1/de not_active Expired - Fee Related
- 1988-12-30 ES ES88121900T patent/ES2059485T3/es not_active Expired - Lifetime
- 1988-12-30 AU AU27628/88A patent/AU635463B2/en not_active Ceased
- 1988-12-30 SU SU884613229A patent/SU1676444A3/ru active
- 1988-12-30 EP EP88121900A patent/EP0324184B1/de not_active Expired - Lifetime
- 1988-12-30 PL PL1988276887A patent/PL155977B1/pl unknown
- 1988-12-30 AT AT88121900T patent/ATE112268T1/de not_active IP Right Cessation
- 1988-12-30 FI FI886046A patent/FI90536C/fi not_active IP Right Cessation
-
1989
- 1989-04-24 SU SU894613894A patent/SU1705287A1/ru active
-
1992
- 1992-09-28 HR HRP920564AA patent/HRP920564A2/hr not_active Application Discontinuation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU589387B2 (en) | Bicyclic heterocyclic piperazine derivatives | |
| MY101748A (en) | Novel 8-chloro-1, 5-benzothiazepine derivatives, processes for preparing the same and pharmaceutical compositions. | |
| HK19486A (en) | Pyridine derivatives | |
| CA2024381A1 (en) | Xanthine compounds | |
| DE3567650D1 (en) | 1,5-benzothiazephine derivatives, processes for preparing the same and pharmaceutical compositions | |
| PT77370B (en) | Process for preparing new pyrazolo <3,4-b> piridine derivatives and pharmaceutical preparations containing the same | |
| IL93999A0 (en) | Naphthalenecarboxylic acid intermediates for the production of podophyllotoxin and related compounds and their preparation | |
| HUT40126A (en) | Process for producing 6,7-disubstituted-1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphtiridine-3-carboxylic acid derivatives and pharmaceutical compositions and food additives containing them | |
| SE8302554D0 (sv) | New azepinoindoles, their production and pharmaceutical compositions containing them | |
| IE882552L (en) | Novel benzimidazole derivatives | |
| ATE36853T1 (de) | Beta-carbolin-3-carbonsaeurederivate und methode zu ihrer herstellung. | |
| CS902588A2 (en) | Method of 2-aminotetrahydroisoquinoline derivatives production | |
| IE792328L (en) | Derivatives of dihydropyrrole and tetrahydropyridine. | |
| YU109684A (en) | Process for making derivatives of bicyclo-(3,2,1)-octancarboxylic acid | |
| DE3160133D1 (en) | 7,8-amino, hydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines, process for their preparation and pharmaceutical compositions containing them | |
| GB2137987B (en) | Process for the preparation of 3,4-dihydro-2-substituted-2h-1,2-benzothiazine-carboxylic acid 1,1-dioxide derivatives | |
| AU562271B2 (en) | Pharmaceutical composition of corazepam and diphenhydramine | |
| MY101746A (en) | 1,5-benzothiazepine derivatives, a process for preparing the same, pharmaceutical compositions as well as the use thereof. | |
| JPS57144277A (en) | Cyclopentabenzofuran derivative | |
| YU43894B (en) | Process for preparing derivatives of penicilan acid 1,1-dioxide | |
| JPS57149289A (en) | Thiazinobenzoazepin derivative |