CS621687A2 - Metod of 2,3,4,5,6,7-hexahydro-2,7-methano-1,5-benzoxazonine's or 1,4-benzoxazonine's pharmacologically active,pain alleviating derivatives production - Google Patents

Metod of 2,3,4,5,6,7-hexahydro-2,7-methano-1,5-benzoxazonine's or 1,4-benzoxazonine's pharmacologically active,pain alleviating derivatives production

Info

Publication number
CS621687A2
CS621687A2 CS876216A CS621687A CS621687A2 CS 621687 A2 CS621687 A2 CS 621687A2 CS 876216 A CS876216 A CS 876216A CS 621687 A CS621687 A CS 621687A CS 621687 A2 CS621687 A2 CS 621687A2
Authority
CS
Czechoslovakia
Prior art keywords
benzoxazonine
metod
methano
hexahydro
pharmacologically active
Prior art date
Application number
CS876216A
Other languages
Czech (cs)
English (en)
Inventor
Friedrich Prof Dr Eiden
Peter Dr Gmeiner
Jurgen Dr Schunemann
Original Assignee
Madaus Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Madaus Ag filed Critical Madaus Ag
Publication of CS621687A2 publication Critical patent/CS621687A2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CS876216A 1986-09-08 1987-08-25 Metod of 2,3,4,5,6,7-hexahydro-2,7-methano-1,5-benzoxazonine's or 1,4-benzoxazonine's pharmacologically active,pain alleviating derivatives production CS621687A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863630539 DE3630539A1 (de) 1986-09-08 1986-09-08 Derivate von 2,3,4,5,6,7-hexahydro-2,7-methano-1,5-benzoxazonin (bzw. -1,4-benzoxazonin), verfahren zu ihrer herstellung und arzneimittel, die diese verbindung enthalten

Publications (1)

Publication Number Publication Date
CS621687A2 true CS621687A2 (en) 1990-09-12

Family

ID=6309142

Family Applications (1)

Application Number Title Priority Date Filing Date
CS876216A CS621687A2 (en) 1986-09-08 1987-08-25 Metod of 2,3,4,5,6,7-hexahydro-2,7-methano-1,5-benzoxazonine's or 1,4-benzoxazonine's pharmacologically active,pain alleviating derivatives production

Country Status (29)

Country Link
US (1) US4859664A (no)
JP (1) JPS6377882A (no)
KR (1) KR910002566B1 (no)
CN (1) CN1020103C (no)
AR (1) AR243190A1 (no)
AT (1) ATA185987A (no)
AU (1) AU590443B2 (no)
BE (1) BE1002121A4 (no)
CH (1) CH675723A5 (no)
CS (1) CS621687A2 (no)
DD (1) DD275052A1 (no)
DE (1) DE3630539A1 (no)
DK (1) DK464487A (no)
ES (1) ES2013322A6 (no)
FI (1) FI88800C (no)
FR (1) FR2603587B1 (no)
GB (1) GB2194786B (no)
GR (1) GR871209B (no)
HU (1) HU203106B (no)
IL (1) IL83156A (no)
IT (1) IT1228437B (no)
NL (1) NL8701938A (no)
NO (1) NO168530C (no)
PL (1) PL154258B1 (no)
PT (1) PT85656B (no)
SE (1) SE8703343L (no)
SU (1) SU1565346A3 (no)
YU (1) YU46068B (no)
ZA (1) ZA876657B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4959360A (en) * 1988-06-01 1990-09-25 Smithkline Beecham Corporation α-adrenergic receptor antagonists
US4963547A (en) * 1988-06-01 1990-10-16 Smithkline Beecham Corporation Alpha-andrenergic receptor antagonists and use thereas
EP0344980A3 (en) * 1988-06-01 1991-05-15 Smithkline Beecham Corporation Alpha-adrenergic receptor antagonists
NZ229300A (en) * 1988-06-01 1991-04-26 Smithkline Beckman Corp Substituted-2-ethenyl-3,4,5,6-tetrahydrothieno (4,3,2-cf)(3)benzazepine derivatives and pharmaceutical compositions
CA1320954C (en) * 1988-06-01 1993-08-03 Smithkline Beckman Corporation .alpha.-adrenergic receptor antagonists
DE4102103A1 (de) * 1991-01-25 1992-08-20 Bayer Ag Substituierte benzoxazepine und benzthiazepine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
US5248645A (en) * 1992-09-01 1993-09-28 Phillips Petroleum Company Ethylene oligomerization

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3124583A (en) * 1964-03-10 Substituted derivatives of
US3118900A (en) * 1962-01-15 1964-01-21 Abbott Lab Substituted derivatives of 3-aza-6, 7-benzo-8-oxa-5-phenylbicyclo[3.3.1]-nonane
US3401166A (en) * 1966-08-01 1968-09-10 Squibb & Sons Inc Therapeutically active benzothiazines
US3446820A (en) * 1967-04-03 1969-05-27 Rexall Drug Chemical Substituted benzoxazocines and intermediates
US3869475A (en) * 1973-04-05 1975-03-04 Yissum Res Dev Co 2,6-methano-benzoxacin compounds
JPS50106985A (no) * 1973-05-08 1975-08-22
US4100277A (en) * 1976-11-08 1978-07-11 American Home Products Corporation 4,1-Benzoxazonine derivatives and process therefor
ES494130A0 (es) * 1979-08-09 1981-10-01 Glaxo Group Ltd Un procedimiento para la preparacion de nuevos derivados de benzoxocina.

Also Published As

Publication number Publication date
FI873852A0 (fi) 1987-09-07
DD275052A1 (de) 1990-01-10
GB8716668D0 (en) 1987-08-19
FI88800B (fi) 1993-03-31
KR910002566B1 (ko) 1991-04-26
JPS6377882A (ja) 1988-04-08
NO168530B (no) 1991-11-25
US4859664A (en) 1989-08-22
GB2194786A (en) 1988-03-16
ZA876657B (en) 1988-03-08
SU1565346A3 (ru) 1990-05-15
ATA185987A (de) 1994-05-15
GB2194786B (en) 1991-01-02
GR871209B (en) 1987-11-30
CN87106267A (zh) 1988-04-13
PL267628A1 (en) 1989-06-12
KR880003945A (ko) 1988-05-31
FI873852A (fi) 1988-03-09
HU203106B (en) 1991-05-28
ES2013322A6 (es) 1990-05-01
FR2603587B1 (fr) 1991-02-01
YU46068B (sh) 1992-12-21
DK464487A (da) 1988-03-09
CH675723A5 (no) 1990-10-31
CN1020103C (zh) 1993-03-17
PL154258B1 (en) 1991-07-31
AU590443B2 (en) 1989-11-02
NO168530C (no) 1992-03-04
JPH0319236B2 (no) 1991-03-14
IT1228437B (it) 1991-06-17
DE3630539A1 (de) 1988-03-10
NO873727D0 (no) 1987-09-07
AU7816287A (en) 1988-03-10
SE8703343L (sv) 1988-03-09
NL8701938A (nl) 1988-04-05
IT8721436A0 (it) 1987-07-24
PT85656A (en) 1987-10-01
IL83156A0 (en) 1987-12-31
SE8703343D0 (sv) 1987-08-28
HUT50180A (en) 1989-12-28
NO873727L (no) 1988-03-09
FI88800C (fi) 1993-07-12
PT85656B (pt) 1990-05-31
BE1002121A4 (fr) 1990-07-17
AR243190A1 (es) 1993-07-30
IL83156A (en) 1992-12-01
FR2603587A1 (fr) 1988-03-11
DK464487D0 (da) 1987-09-07

Similar Documents

Publication Publication Date Title
KR0140889B1 (en) Production of 2',3'-dideoxy-2',3'-didehydronucleosides
EP0248594A3 (en) Pharmacologically active 1,5-diaryl-3-substituted-pyrazopharmacologically active 1,5-diaryl-3-substituted-pyrazoles and method for synthesizing the same les and method for synthesizing the same
AU7277987A (en) Pharmaceutically active tetrahydronaphthalene derivatives
NO173653C (no) Analogifremgangsmaate for fresmstilling av terapeutisk aktive 6-benzoksazinyl-og 6-benzotianzinyl-2,3,4,5-tetrahydropyridazin-3-oner
DE3464322D1 (en) Patient's support
EP0185210A3 (en) Use of dipeptide derivatives for the preparation of medicaments for the treatment of sufferers from amyotrophic lateral sclerosis
AR242561A1 (es) Procedimiento para la preparacion de clorhidrato de s-(-)-1-propil-2',6'-pipecoloxilidida opticamente sustancialmente puro y procedimiento
DE3566220D1 (en) Patient's support
NZ220179A (en) 4,5-dihydro-oxazoles, thiazoles and imidazoles and pharmaceutical compositions
EG18544A (en) Six - membred heterocyclic derivatives of n', - substituted - n, n'-diacylhydrazines
CS621687A2 (en) Metod of 2,3,4,5,6,7-hexahydro-2,7-methano-1,5-benzoxazonine's or 1,4-benzoxazonine's pharmacologically active,pain alleviating derivatives production
CS554387A2 (en) Method of pyrimidine's new derivatives production
EP0264744A3 (en) Process for the preparation of 4,4'-diaminodiphenylmethane and its derivatives.
CS523687A2 (en) Method of pyrimidine's new derivatives production
ZA902566B (en) 2-substituted n,n'-ditrimethoxybenzoyl piperazines,a preparation process of the samde and therapeutic compositions containing them
CS203587A2 (en) Method of 5-chloro-7-iodo-8-hydroxyquinoline's pharmaceutically pure zinc complex preparation
ZA876845B (en) Pharmacologically active compounds and use
CS960486A2 (en) Method of pregnale-21-acid's 16,17-acetal-substituted derivatives production
NZ224812A (en) Derivatives of 2',3'-dideoxycytidine and pharmaceutical compositions
PT85518A (en) Process for the preparation of antibacterial 7-oxo-4-thia-1-aza-bicyclo ]3.2.o" hept-2-ene derivatives
FI894813A0 (fi) Menetelmä terapeuttisesti aktiivisten 2-metoksikarbonyylisubstituoitujen N,N'-di(trimetoksibentsoyyli)piperatsiinijohdannaisten valmistamiseksi
AU589100B2 (en) Process for the preparation of N,N'-tetrathiodimorpholine
AU7534787A (en) Pharmacologically active compounds and use
IL88296A0 (en) Preparation of 1,5-benzothiazepine derivatives
IL106709A0 (en) Therapeutic uses of 2',5'-oligoadenylates