CS409491A3 - Derivatives of amino acids, process of their preparation, agents comprising said compounds and their application - Google Patents
Derivatives of amino acids, process of their preparation, agents comprising said compounds and their applicationInfo
- Publication number
- CS409491A3 CS409491A3 CS914094A CS409491A CS409491A3 CS 409491 A3 CS409491 A3 CS 409491A3 CS 914094 A CS914094 A CS 914094A CS 409491 A CS409491 A CS 409491A CS 409491 A3 CS409491 A3 CS 409491A3
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- derivatives
- agents
- compounds
- preparation
- application
- Prior art date
Links
- 150000001413 amino acids Chemical class 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Furan Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19803032709 DE3032709A1 (de) | 1980-08-30 | 1980-08-30 | Aminosaeurederivate, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung |
DE19813118191 DE3118191A1 (de) | 1981-05-08 | 1981-05-08 | Aminosaeurederivate, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
CS409491A3 true CS409491A3 (en) | 1992-05-13 |
Family
ID=25787513
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS914094A CS409491A3 (en) | 1980-08-30 | 1991-12-27 | Derivatives of amino acids, process of their preparation, agents comprising said compounds and their application |
Country Status (18)
Country | Link |
---|---|
US (2) | US5158959A (pt) |
EP (2) | EP0278530A3 (pt) |
JP (3) | JPS5777672A (pt) |
KR (3) | KR850001269B1 (pt) |
AR (2) | AR240949A1 (pt) |
AU (2) | AU599151B2 (pt) |
CS (1) | CS409491A3 (pt) |
DE (2) | DE3177311D1 (pt) |
DK (1) | DK169382B1 (pt) |
ES (3) | ES504955A0 (pt) |
FI (1) | FI90072C (pt) |
GR (1) | GR75331B (pt) |
HU (1) | HU189531B (pt) |
IE (1) | IE67438B1 (pt) |
NO (1) | NO812933L (pt) |
NZ (1) | NZ198195A (pt) |
PH (1) | PH16812A (pt) |
PT (1) | PT73584B (pt) |
Families Citing this family (90)
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DE3177311D1 (de) * | 1980-08-30 | 1994-06-09 | Hoechst Ag | Aminosäurederivate, Verfahren zu ihrer Herstellung, diese enthaltende Mittel und deren Verwendung. |
US4344949A (en) * | 1980-10-03 | 1982-08-17 | Warner-Lambert Company | Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids |
ZA817261B (en) * | 1980-10-23 | 1982-09-29 | Schering Corp | Carboxyalkyl dipeptides,processes for their production and pharmaceutical compositions containing them |
LU88621I2 (fr) * | 1980-10-23 | 1995-09-01 | Schering Corp | Sandopril |
US4479963A (en) * | 1981-02-17 | 1984-10-30 | Ciba-Geigy Corporation | 1-Carboxyalkanoylindoline-2-carboxylic acids |
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IN156096B (pt) * | 1981-03-19 | 1985-05-11 | Usv Pharma Corp | |
JPS5833430A (ja) * | 1981-03-25 | 1983-02-26 | Showa Denko Kk | 吹込成形金型 |
EP0065301A1 (en) * | 1981-05-18 | 1982-11-24 | Merck & Co. Inc. | Isoquinoline carboxylic acid derivates, process for preparing and pharmaceutical composition containing the same |
SU1327787A3 (ru) * | 1981-11-05 | 1987-07-30 | Хехст Аг (Фирма) | Способ получени цис,эндо-2-азабицикло-/3,3,0/-октан-3-карбоновых кислот или их кислотно-аддитивных солей |
DE3226768A1 (de) * | 1981-11-05 | 1983-05-26 | Hoechst Ag, 6230 Frankfurt | Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung |
EP0079522B1 (en) * | 1981-11-09 | 1986-05-07 | Merck & Co. Inc. | N-carboxymethyl(amidino)lysyl-proline antihypertensive agents |
NZ202903A (en) * | 1981-12-29 | 1988-01-08 | Hoechst Ag | 1-- pe pyrrol-2-yl-carboxylic acid derivatives and pharmaceutical compositions |
DE3227055A1 (de) * | 1982-07-20 | 1984-01-26 | Hoechst Ag, 6230 Frankfurt | Neue derivate der 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure als zwischenstufe und verfahren zu deren herstellung |
US4500713A (en) * | 1982-09-23 | 1985-02-19 | Usv Pharmaceutical Corporation | Therapeutic dipeptides |
DE3302125A1 (de) * | 1983-01-22 | 1984-07-26 | Boehringer Ingelheim KG, 6507 Ingelheim | Aminosaeure-derivate, verfahren zu ihrer herstellung und verwendung |
US5175306A (en) * | 1983-01-31 | 1992-12-29 | Hoechst Aktiengesellschaft | Process for the resolution of racemates of optically active bicyclic imino-α-carboxylic esters |
DE3303344A1 (de) | 1983-02-02 | 1984-08-02 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von n-alkylierten aminosaeuren und deren estern |
FI841052A (fi) * | 1983-03-16 | 1984-09-17 | Usv Pharma Corp | Foereningar foer behandling av blodtryckssjukdomar. |
DE3315464A1 (de) * | 1983-04-28 | 1984-10-31 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern |
FR2546886B2 (fr) * | 1983-06-06 | 1986-05-16 | Adir | Derives d'acides isoindoledicarboxyliques, leur preparation et compositions pharmaceutiques les contenant |
DE3333455A1 (de) * | 1983-09-16 | 1985-04-11 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung n-alkylierter dipeptide und deren estern |
DE3333454A1 (de) * | 1983-09-16 | 1985-04-11 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern |
DE3408923A1 (de) * | 1984-03-12 | 1985-09-26 | Hoechst Ag, 6230 Frankfurt | Carboxyalkyldipeptidderivate, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung |
DE3410732A1 (de) * | 1984-03-23 | 1985-09-26 | Hoechst Ag, 6230 Frankfurt | Methode zur behandlung des glaukoms |
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ZA817261B (en) * | 1980-10-23 | 1982-09-29 | Schering Corp | Carboxyalkyl dipeptides,processes for their production and pharmaceutical compositions containing them |
LU88621I2 (fr) * | 1980-10-23 | 1995-09-01 | Schering Corp | Sandopril |
US4374847A (en) * | 1980-10-27 | 1983-02-22 | Ciba-Geigy Corporation | 1-Carboxyalkanoylindoline-2-carboxylic acids |
US4512979A (en) * | 1981-03-23 | 1985-04-23 | Merck & Co., Inc. | Dipeptides containing thialysine and related amino acids as antihypertensives |
US4374817A (en) * | 1981-08-21 | 1983-02-22 | Fmc Corporation | Formulation of phosphate rock slurries |
DE3134933A1 (de) * | 1981-09-03 | 1983-03-31 | Hoechst Ag, 6230 Frankfurt | "harnstoffderivate, verfahren zu ihrer herstellung und diese enthaltende medikamente sowie deren verwendung" |
US4431645A (en) * | 1982-03-08 | 1984-02-14 | Schering Corporation | Antihypertensive agents |
US4431644A (en) * | 1982-03-08 | 1984-02-14 | Schering Corporation | Antihypertensive agents |
US4500713A (en) * | 1982-09-23 | 1985-02-19 | Usv Pharmaceutical Corporation | Therapeutic dipeptides |
US4490386A (en) * | 1982-09-23 | 1984-12-25 | Warner-Lambert Company | Phosphate salts of 1-[2-[(1-alkoxycarbonyl-3-aralkyl)-amino]-1-oxoalkyl]octahydro-1H-indole-2-carboxylic acids, preparation of, and medical compositions thereof |
US4468396A (en) * | 1982-12-20 | 1984-08-28 | Schering Corporation | Antihypertensive benzothiadiazines |
-
1981
- 1981-08-22 DE DE3177311T patent/DE3177311D1/de not_active Expired - Lifetime
- 1981-08-22 EP EP88102408A patent/EP0278530A3/de not_active Ceased
- 1981-08-22 EP EP81106535A patent/EP0046953B1/de not_active Expired
- 1981-08-22 DE DE8181106535T patent/DE3177130D1/de not_active Expired - Lifetime
- 1981-08-25 ES ES504955A patent/ES504955A0/es active Granted
- 1981-08-27 FI FI812652A patent/FI90072C/fi not_active IP Right Cessation
- 1981-08-27 HU HU812478A patent/HU189531B/hu unknown
- 1981-08-27 PT PT73584A patent/PT73584B/pt unknown
- 1981-08-28 NZ NZ198195A patent/NZ198195A/en unknown
- 1981-08-28 GR GR65886A patent/GR75331B/el unknown
- 1981-08-28 NO NO812933A patent/NO812933L/no unknown
- 1981-08-28 AR AR286576A patent/AR240949A1/es active
- 1981-08-28 DK DK383581A patent/DK169382B1/da active
- 1981-08-28 KR KR1019810003193A patent/KR850001269B1/ko active
- 1981-08-28 PH PH26117A patent/PH16812A/en unknown
- 1981-08-28 IE IE198681A patent/IE67438B1/en not_active IP Right Cessation
- 1981-08-28 JP JP56134401A patent/JPS5777672A/ja active Pending
- 1981-09-18 ES ES505604A patent/ES505604A0/es active Granted
- 1981-09-18 ES ES505605A patent/ES8301215A1/es not_active Expired
-
1982
- 1982-06-29 AR AR28982682A patent/AR240702A1/es active
-
1983
- 1983-12-27 US US06/565,900 patent/US5158959A/en not_active Expired - Lifetime
-
1984
- 1984-09-27 KR KR1019840005957A patent/KR850001270B1/ko not_active IP Right Cessation
- 1984-09-27 KR KR1019840006028A patent/KR850001288B1/ko not_active IP Right Cessation
-
1987
- 1987-10-01 AU AU79284/87A patent/AU599151B2/en not_active Expired
-
1988
- 1988-08-25 JP JP63209625A patent/JPH0678355B2/ja not_active Expired - Lifetime
-
1989
- 1989-06-20 AU AU36625/89A patent/AU627741B2/en not_active Expired
-
1991
- 1991-03-18 JP JP3077208A patent/JPH07121955B2/ja not_active Expired - Lifetime
- 1991-12-27 CS CS914094A patent/CS409491A3/cs unknown
-
1994
- 1994-03-09 US US08/208,443 patent/US5401766A/en not_active Expired - Lifetime
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