CS277405B6 - Peptides with 1-amino-1-cycloalkane carboxylic acid - Google Patents

Peptides with 1-amino-1-cycloalkane carboxylic acid Download PDF

Info

Publication number
CS277405B6
CS277405B6 CS864332A CS433286A CS277405B6 CS 277405 B6 CS277405 B6 CS 277405B6 CS 864332 A CS864332 A CS 864332A CS 433286 A CS433286 A CS 433286A CS 277405 B6 CS277405 B6 CS 277405B6
Authority
CS
Czechoslovakia
Prior art keywords
amino
alanine
residue
ethyl ester
cyclopentanecarboxylic acid
Prior art date
Application number
CS864332A
Other languages
Czech (cs)
English (en)
Other versions
CS433286A3 (en
Inventor
Evzen Ing Csc Kasafirek
Miroslav Ing Csc Rybak
Ivan Rndr Phmr Csc Krejci
Antonin Ing Sturc
Alena Roubalova
Jiri Rndr Csc Vanzura
Evzen Mudr Csc Krepela
Michal Prof Mvdr Drsc Bartik
Original Assignee
Vyzk Ustav Farm Biochem Sp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vyzk Ustav Farm Biochem Sp filed Critical Vyzk Ustav Farm Biochem Sp
Priority to CS864332A priority Critical patent/CS277405B6/cs
Priority to CA000537992A priority patent/CA1308515C/en
Priority to AT8787305065T priority patent/ATE105300T1/de
Priority to EP87305065A priority patent/EP0249434B1/de
Priority to DE3789729T priority patent/DE3789729T2/de
Priority to JP62144207A priority patent/JPH082916B2/ja
Priority to US07/062,300 priority patent/US4898930A/en
Publication of CS433286A3 publication Critical patent/CS433286A3/cs
Publication of CS277405B6 publication Critical patent/CS277405B6/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
CS864332A 1986-06-12 1986-06-12 Peptides with 1-amino-1-cycloalkane carboxylic acid CS277405B6 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CS864332A CS277405B6 (en) 1986-06-12 1986-06-12 Peptides with 1-amino-1-cycloalkane carboxylic acid
CA000537992A CA1308515C (en) 1986-06-12 1987-05-26 Peptide derivatives and processes for their preparation
AT8787305065T ATE105300T1 (de) 1986-06-12 1987-06-09 Peptidderivate und verfahren zu deren herstellung.
EP87305065A EP0249434B1 (de) 1986-06-12 1987-06-09 Peptidderivate und Verfahren zu deren Herstellung
DE3789729T DE3789729T2 (de) 1986-06-12 1987-06-09 Peptidderivate und Verfahren zu deren Herstellung.
JP62144207A JPH082916B2 (ja) 1986-06-12 1987-06-11 ペプチド誘導体類及びそれらの製造方法
US07/062,300 US4898930A (en) 1986-06-12 1987-06-12 Peptide derivatives and processes for their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS864332A CS277405B6 (en) 1986-06-12 1986-06-12 Peptides with 1-amino-1-cycloalkane carboxylic acid

Publications (2)

Publication Number Publication Date
CS433286A3 CS433286A3 (en) 1992-08-12
CS277405B6 true CS277405B6 (en) 1993-03-17

Family

ID=5385817

Family Applications (1)

Application Number Title Priority Date Filing Date
CS864332A CS277405B6 (en) 1986-06-12 1986-06-12 Peptides with 1-amino-1-cycloalkane carboxylic acid

Country Status (7)

Country Link
US (1) US4898930A (de)
EP (1) EP0249434B1 (de)
JP (1) JPH082916B2 (de)
AT (1) ATE105300T1 (de)
CA (1) CA1308515C (de)
CS (1) CS277405B6 (de)
DE (1) DE3789729T2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ2001253A3 (cs) * 1998-07-20 2001-11-14 Societe De Conseils De Recherches Et D'application Peptidové analogy PACAP
CN1164611C (zh) * 2002-06-17 2004-09-01 厦门大学 丙-谷二肽合成方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3704288A (en) * 1970-04-16 1972-11-28 Joseph A Skorcz L-tyrosyl-1-aminocyclopentane-1-carbonyl-l-phenylalanine
NO774303L (no) * 1976-12-28 1978-06-29 Troponwerke Gmbh & Co Kg Nye dehydrooligopeptider, fremgangsmaate til deres fremstilling samt deres anvendelse som legemiddel
US4278595A (en) * 1979-12-10 1981-07-14 Vega Laboratories, Inc. Orally active MIF analogs with an effect on the central nervous system
US4690936A (en) * 1980-03-05 1987-09-01 University Of Miami Anti-hypertensive agents
CS231227B1 (en) * 1982-10-01 1984-10-15 Evzen Kasafirek 2,5-pierazindion derivatives
DE3300774A1 (de) * 1983-01-12 1984-07-12 Hoechst Ag, 6230 Frankfurt Neue spirocyclische aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue spirocyclische aminosaeuren als zwischenprodukte und verfahren zu deren herstellung
DE3485587D1 (de) * 1983-08-16 1992-04-23 Univ Georgia Res Found Herstellung von aminocyclopropancarbonsaeuren und von peptiden.
EP0212550A3 (de) * 1985-08-14 1989-05-10 G.D. Searle & Co. Substituierte Dipeptidamide

Also Published As

Publication number Publication date
CS433286A3 (en) 1992-08-12
JPH082916B2 (ja) 1996-01-17
EP0249434B1 (de) 1994-05-04
EP0249434A2 (de) 1987-12-16
US4898930A (en) 1990-02-06
EP0249434A3 (en) 1990-01-24
CA1308515C (en) 1992-10-06
ATE105300T1 (de) 1994-05-15
DE3789729D1 (de) 1994-06-09
JPS633000A (ja) 1988-01-07
DE3789729T2 (de) 1994-08-18

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Legal Events

Date Code Title Description
IF00 In force as of 2000-06-30 in czech republic
MM4A Patent lapsed due to non-payment of fee

Effective date: 20000612