CS270242B2 - Method of dihydropyridines production - Google Patents

Method of dihydropyridines production Download PDF

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Publication number
CS270242B2
CS270242B2 CS882734A CS273488A CS270242B2 CS 270242 B2 CS270242 B2 CS 270242B2 CS 882734 A CS882734 A CS 882734A CS 273488 A CS273488 A CS 273488A CS 270242 B2 CS270242 B2 CS 270242B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
compound
group
compounds
process according
Prior art date
Application number
CS882734A
Other languages
Czech (cs)
English (en)
Other versions
CS273488A2 (en
Inventor
David Dr Alker
Peter E Dr Cross
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of CS273488A2 publication Critical patent/CS273488A2/cs
Publication of CS270242B2 publication Critical patent/CS270242B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/82—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
CS882734A 1987-04-21 1988-04-21 Method of dihydropyridines production CS270242B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878709447A GB8709447D0 (en) 1987-04-21 1987-04-21 Dihydropyridines

Publications (2)

Publication Number Publication Date
CS273488A2 CS273488A2 (en) 1989-10-13
CS270242B2 true CS270242B2 (en) 1990-06-13

Family

ID=10616115

Family Applications (1)

Application Number Title Priority Date Filing Date
CS882734A CS270242B2 (en) 1987-04-21 1988-04-21 Method of dihydropyridines production

Country Status (19)

Country Link
US (1) US4957930A (ko)
EP (1) EP0295769A3 (ko)
JP (1) JPS63280062A (ko)
KR (1) KR880012554A (ko)
CN (1) CN88102381A (ko)
AU (1) AU592498B2 (ko)
CS (1) CS270242B2 (ko)
DD (1) DD273437A5 (ko)
DK (1) DK213988A (ko)
FI (1) FI881824A (ko)
GB (1) GB8709447D0 (ko)
HU (1) HUT46894A (ko)
IL (1) IL86108A0 (ko)
NO (1) NO881709L (ko)
NZ (1) NZ224298A (ko)
PL (1) PL271920A1 (ko)
PT (1) PT87272A (ko)
YU (1) YU78388A (ko)
ZA (1) ZA882765B (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2014089C (en) * 1989-07-21 1997-01-14 Vernon L. Lamb Apparatus and method for making pressboard from poly-coated paper using relative movement of facing webs
CN103274993A (zh) * 2013-06-13 2013-09-04 南京工业大学 二氢吡啶和吡咯类杂环的新合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DK161312C (da) * 1982-03-11 1991-12-09 Pfizer Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden
JPS60120861A (ja) * 1983-12-02 1985-06-28 Otsuka Pharmaceut Co Ltd ジヒドロピリジン誘導体
GB8412208D0 (en) * 1984-05-12 1984-06-20 Pfizer Ltd Quinolone inotropic agents
IL78642A0 (en) * 1985-05-03 1986-08-31 Pfizer Dihydropyridines and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
HUT46894A (en) 1988-12-28
DD273437A5 (de) 1989-11-15
PT87272A (pt) 1989-05-12
US4957930A (en) 1990-09-18
YU78388A (en) 1990-04-30
ZA882765B (en) 1989-12-27
CN88102381A (zh) 1988-11-09
NZ224298A (en) 1990-03-27
FI881824A (fi) 1988-10-22
EP0295769A2 (en) 1988-12-21
PL271920A1 (en) 1989-03-20
FI881824A0 (fi) 1988-04-19
AU592498B2 (en) 1990-01-11
JPS63280062A (ja) 1988-11-17
CS273488A2 (en) 1989-10-13
IL86108A0 (en) 1988-11-15
AU1478788A (en) 1988-10-27
DK213988A (da) 1988-10-22
EP0295769A3 (en) 1989-02-08
KR880012554A (ko) 1988-11-28
NO881709D0 (no) 1988-04-20
GB8709447D0 (en) 1987-05-28
NO881709L (no) 1988-10-24
DK213988D0 (da) 1988-04-20

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