CS244448B2 - Method of aminopyrimidine derivatives production - Google Patents
Method of aminopyrimidine derivatives production Download PDFInfo
- Publication number
- CS244448B2 CS244448B2 CS845810A CS581084A CS244448B2 CS 244448 B2 CS244448 B2 CS 244448B2 CS 845810 A CS845810 A CS 845810A CS 581084 A CS581084 A CS 581084A CS 244448 B2 CS244448 B2 CS 244448B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- formula
- group
- compound
- compounds
- residue
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Steroid Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB838320505A GB8320505D0 (en) | 1983-07-29 | 1983-07-29 | Chemical compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS581084A2 CS581084A2 (en) | 1985-08-15 |
| CS244448B2 true CS244448B2 (en) | 1986-07-17 |
Family
ID=10546495
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS845810A CS244448B2 (en) | 1983-07-29 | 1984-07-27 | Method of aminopyrimidine derivatives production |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0134096B1 (de) |
| JP (1) | JPS6051179A (de) |
| KR (1) | KR850001174A (de) |
| AT (1) | ATE40552T1 (de) |
| AU (1) | AU564650B2 (de) |
| CA (1) | CA1261831A (de) |
| CS (1) | CS244448B2 (de) |
| DD (1) | DD216933A5 (de) |
| DE (1) | DE3476541D1 (de) |
| DK (1) | DK368284A (de) |
| ES (1) | ES8600254A1 (de) |
| FI (1) | FI842976A7 (de) |
| GB (1) | GB8320505D0 (de) |
| GR (1) | GR82226B (de) |
| HU (1) | HUT34743A (de) |
| IL (1) | IL72491A0 (de) |
| JO (1) | JO1327B1 (de) |
| NO (1) | NO843043L (de) |
| PT (1) | PT78977B (de) |
| ZA (1) | ZA845820B (de) |
| ZW (1) | ZW11584A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4772704A (en) * | 1983-09-21 | 1988-09-20 | Bristol-Myers Company | 2,5-disubstituted-4(3H)-pyrimidones having histamine H2 -receptor antagonist activity |
| GB8421427D0 (en) * | 1984-08-23 | 1984-09-26 | Smith Kline French Lab | Chemical compounds |
| JP2007531753A (ja) | 2004-03-31 | 2007-11-08 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 非イミダゾール系複素環式化合物 |
| MX339668B (es) | 2006-05-30 | 2016-06-02 | Janssen Pharmaceutica N V * | Compuestos de piridil amida sustituidos como moduladores del receptor h3 de la histamina. |
| CN105712977B (zh) | 2007-11-20 | 2021-06-29 | 詹森药业有限公司 | 作为组胺h3受体调节剂的环烷基氧基吡啶化合物和杂环烷基氧基吡啶化合物 |
| WO2022034121A1 (en) | 2020-08-11 | 2022-02-17 | Université De Strasbourg | H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN151188B (de) * | 1978-02-13 | 1983-03-05 | Smith Kline French Lab | |
| ZA793443B (en) * | 1978-07-26 | 1980-12-31 | Glaxo Group Ltd | Heterocyclic derivatives |
| US4496567A (en) * | 1978-11-13 | 1985-01-29 | Smith Kline & French Laboratories Limited | Phenyl alkylaminopyrimidones |
| US4521418A (en) * | 1979-02-21 | 1985-06-04 | Smith Kline & French Laboratories Limited | Guanidinothiazolyl derivatives |
| ZW21281A1 (en) * | 1980-10-01 | 1981-11-18 | Smith Kline French Lab | Amine derivatives |
| NZ202797A (en) * | 1981-12-28 | 1985-08-30 | Lilly Co Eli | Pyrimidine derivatives and pharmaceutical compositions |
-
1983
- 1983-07-29 GB GB838320505A patent/GB8320505D0/en active Pending
-
1984
- 1984-07-18 JO JO19841327A patent/JO1327B1/en active
- 1984-07-23 GR GR75407A patent/GR82226B/el unknown
- 1984-07-24 AU AU30991/84A patent/AU564650B2/en not_active Ceased
- 1984-07-24 CA CA000459505A patent/CA1261831A/en not_active Expired
- 1984-07-25 EP EP84305045A patent/EP0134096B1/de not_active Expired
- 1984-07-25 PT PT78977A patent/PT78977B/pt unknown
- 1984-07-25 AT AT84305045T patent/ATE40552T1/de not_active IP Right Cessation
- 1984-07-25 IL IL72491A patent/IL72491A0/xx unknown
- 1984-07-25 DE DE8484305045T patent/DE3476541D1/de not_active Expired
- 1984-07-26 FI FI842976A patent/FI842976A7/fi not_active Application Discontinuation
- 1984-07-26 ES ES534620A patent/ES8600254A1/es not_active Expired
- 1984-07-27 JP JP59158537A patent/JPS6051179A/ja active Pending
- 1984-07-27 HU HU842902A patent/HUT34743A/hu unknown
- 1984-07-27 ZA ZA845820A patent/ZA845820B/xx unknown
- 1984-07-27 NO NO843043A patent/NO843043L/no unknown
- 1984-07-27 DD DD84265728A patent/DD216933A5/de unknown
- 1984-07-27 DK DK368284A patent/DK368284A/da not_active Application Discontinuation
- 1984-07-27 KR KR1019840004474A patent/KR850001174A/ko not_active Withdrawn
- 1984-07-27 CS CS845810A patent/CS244448B2/cs unknown
- 1984-07-27 ZW ZW115/84A patent/ZW11584A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL72491A0 (en) | 1984-11-30 |
| CS581084A2 (en) | 1985-08-15 |
| GB8320505D0 (en) | 1983-09-01 |
| EP0134096A3 (en) | 1985-12-18 |
| JO1327B1 (en) | 1986-11-30 |
| FI842976L (fi) | 1985-01-30 |
| EP0134096A2 (de) | 1985-03-13 |
| AU564650B2 (en) | 1987-08-20 |
| KR850001174A (ko) | 1985-03-16 |
| GR82226B (de) | 1984-12-13 |
| FI842976A0 (fi) | 1984-07-26 |
| ZW11584A1 (en) | 1985-04-17 |
| DE3476541D1 (de) | 1989-03-09 |
| ATE40552T1 (de) | 1989-02-15 |
| PT78977B (en) | 1986-06-05 |
| AU3099184A (en) | 1985-01-31 |
| FI842976A7 (fi) | 1985-01-30 |
| DK368284D0 (da) | 1984-07-27 |
| DD216933A5 (de) | 1985-01-02 |
| NO843043L (no) | 1985-01-30 |
| PT78977A (en) | 1984-08-01 |
| HUT34743A (en) | 1985-04-28 |
| DK368284A (da) | 1985-01-30 |
| ES534620A0 (es) | 1985-09-16 |
| ES8600254A1 (es) | 1985-09-16 |
| JPS6051179A (ja) | 1985-03-22 |
| EP0134096B1 (de) | 1989-02-01 |
| CA1261831A (en) | 1989-09-26 |
| ZA845820B (en) | 1985-06-26 |
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