CS240963B2 - Production method of indolizine derivatives - Google Patents

Production method of indolizine derivatives Download PDF

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Publication number
CS240963B2
CS240963B2 CS834401A CS440183A CS240963B2 CS 240963 B2 CS240963 B2 CS 240963B2 CS 834401 A CS834401 A CS 834401A CS 440183 A CS440183 A CS 440183A CS 240963 B2 CS240963 B2 CS 240963B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
indolizine
pharmaceutically acceptable
acid
primary amine
Prior art date
Application number
CS834401A
Other languages
Czech (cs)
English (en)
Other versions
CS440183A2 (en
Inventor
Gilbert Rosseels
Peter Polster
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of CS440183A2 publication Critical patent/CS440183A2/cs
Publication of CS240963B2 publication Critical patent/CS240963B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Telephonic Communication Services (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • External Artificial Organs (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CS834401A 1982-06-17 1983-06-16 Production method of indolizine derivatives CS240963B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8210598A FR2528845A1 (fr) 1982-06-17 1982-06-17 Nouveaux derives d'indolizine, leur procede de preparation ainsi que les compositions therapeutiques les contenant

Publications (2)

Publication Number Publication Date
CS440183A2 CS440183A2 (en) 1985-06-13
CS240963B2 true CS240963B2 (en) 1986-03-13

Family

ID=9275110

Family Applications (1)

Application Number Title Priority Date Filing Date
CS834401A CS240963B2 (en) 1982-06-17 1983-06-16 Production method of indolizine derivatives

Country Status (25)

Country Link
US (1) US4499095A (xx)
EP (1) EP0097636B1 (xx)
JP (1) JPS5980682A (xx)
KR (1) KR870001065B1 (xx)
AT (1) ATE15042T1 (xx)
AU (1) AU553758B2 (xx)
BE (1) BE897059A (xx)
CA (1) CA1195979A (xx)
CS (1) CS240963B2 (xx)
DD (1) DD210046A5 (xx)
DE (1) DE3360609D1 (xx)
DK (1) DK158000C (xx)
ES (1) ES523389A0 (xx)
FI (1) FI74000C (xx)
FR (1) FR2528845A1 (xx)
GR (1) GR78285B (xx)
HU (1) HU189298B (xx)
IE (1) IE55429B1 (xx)
IL (1) IL68778A (xx)
NO (1) NO159723C (xx)
NZ (1) NZ204608A (xx)
PT (1) PT76876B (xx)
SU (1) SU1194272A3 (xx)
YU (1) YU43313B (xx)
ZA (1) ZA833875B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5215988A (en) * 1986-02-14 1993-06-01 Sanofi Aminoalkoxyphenyl derivatives, process of preparation and compositions containing the same
FR2642755B1 (xx) * 1989-02-07 1993-11-05 Sanofi
FR2642756B1 (fr) * 1989-02-07 1994-03-04 Sanofi Derives cycloaminoalkoxyphenyle, leur procede de preparation ainsi que les compositions pharmaceutiques ou veterinaires en contenant
AU668691B2 (en) * 1991-08-09 1996-05-16 Nycomed Innovation Ab Use of persistent free-radicals in magnetic resonance imaging
FR2838123B1 (fr) * 2002-04-04 2005-06-10 Sanofi Synthelabo Nouveaux derives d'indolozine-1,2,3 substituee, inhibiteurs selectifs du b-fgf
FR2859997B1 (fr) * 2003-09-18 2006-02-03 Sanofi Synthelabo Nouveaux derives d'indolizine 1,2,3,6,7,8 substituee, inhibiteurs des fgfs, leur procede de preparation et les compositions pharmaceutiques les contenant.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI61030C (fi) * 1976-02-19 1982-05-10 Sanofi Sa Foerfarande foer framstaellning av terapeutiskt verkande 2-substituerade-1- eller 3-benzoyl-indolizinderivat
US4378362A (en) * 1979-12-06 1983-03-29 S.A. Labaz N.V. Indolizine derivatives and process for preparing the same
FR2495616A1 (fr) * 1980-12-09 1982-06-11 Labaz Nv Nouveaux derives d'indolizine, leur procede de preparation ainsi que leurs applications en therapeutique

Also Published As

Publication number Publication date
YU43313B (en) 1989-06-30
IL68778A0 (en) 1983-09-30
JPS5980682A (ja) 1984-05-10
IE55429B1 (en) 1990-09-12
FI74000B (fi) 1987-08-31
IL68778A (en) 1986-10-31
IE831408L (en) 1983-12-17
ES8403900A1 (es) 1984-04-01
DK158000B (da) 1990-03-12
PT76876A (en) 1983-07-01
FI832209L (fi) 1983-12-18
FR2528845A1 (fr) 1983-12-23
EP0097636B1 (fr) 1985-08-21
NO832176L (no) 1983-12-19
CS440183A2 (en) 1985-06-13
KR840005140A (ko) 1984-11-03
US4499095A (en) 1985-02-12
DK158000C (da) 1990-08-20
DK276183D0 (da) 1983-06-15
NZ204608A (en) 1985-09-13
JPH0372072B2 (xx) 1991-11-15
NO159723B (no) 1988-10-24
HU189298B (en) 1986-06-30
AU553758B2 (en) 1986-07-24
ATE15042T1 (de) 1985-09-15
ES523389A0 (es) 1984-04-01
SU1194272A3 (ru) 1985-11-23
ZA833875B (en) 1984-02-29
NO159723C (no) 1989-02-01
DD210046A5 (de) 1984-05-30
FI832209A0 (fi) 1983-06-16
DK276183A (da) 1983-12-18
GR78285B (xx) 1984-09-26
EP0097636A1 (fr) 1984-01-04
YU133183A (en) 1986-02-28
FR2528845B1 (xx) 1984-11-23
PT76876B (en) 1986-01-27
DE3360609D1 (en) 1985-09-26
CA1195979A (en) 1985-10-29
KR870001065B1 (ko) 1987-05-27
BE897059A (fr) 1983-12-16
FI74000C (fi) 1987-12-10
AU1542483A (en) 1984-12-20

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