CS239947B2 - Processing of new benzazepin derivatives - Google Patents

Processing of new benzazepin derivatives Download PDF

Info

Publication number
CS239947B2
CS239947B2 CS838456A CS845683A CS239947B2 CS 239947 B2 CS239947 B2 CS 239947B2 CS 838456 A CS838456 A CS 838456A CS 845683 A CS845683 A CS 845683A CS 239947 B2 CS239947 B2 CS 239947B2
Authority
CS
Czechoslovakia
Prior art keywords
group
amino
methyl
benzazepin
tetrahydro
Prior art date
Application number
CS838456A
Other languages
Czech (cs)
English (en)
Inventor
Manfred Reiffen
Joachim Heider
Volkhard Austal
Norbert Hauel
Walter Kobinger
Christian Lilie
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of CS239947B2 publication Critical patent/CS239947B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
CS838456A 1982-11-18 1983-11-15 Processing of new benzazepin derivatives CS239947B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823242599 DE3242599A1 (de) 1982-11-18 1982-11-18 Neue benzazepinderivate, ihre herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
CS239947B2 true CS239947B2 (en) 1986-01-16

Family

ID=6178417

Family Applications (1)

Application Number Title Priority Date Filing Date
CS838456A CS239947B2 (en) 1982-11-18 1983-11-15 Processing of new benzazepin derivatives

Country Status (23)

Country Link
EP (1) EP0109636B1 (ko)
JP (1) JPS59106466A (ko)
KR (1) KR840006628A (ko)
AT (1) ATE40118T1 (ko)
AU (1) AU568101B2 (ko)
CA (1) CA1211107A (ko)
CS (1) CS239947B2 (ko)
DD (1) DD215540A5 (ko)
DE (2) DE3242599A1 (ko)
DK (1) DK527483A (ko)
ES (2) ES8502424A1 (ko)
FI (1) FI834174A (ko)
GB (1) GB2130213B (ko)
GR (1) GR81253B (ko)
HU (1) HU193189B (ko)
IE (1) IE56261B1 (ko)
IL (1) IL70258A (ko)
NO (1) NO834222L (ko)
NZ (1) NZ206305A (ko)
PL (1) PL139449B1 (ko)
PT (1) PT77683B (ko)
YU (1) YU226283A (ko)
ZA (1) ZA838572B (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3418271A1 (de) * 1984-05-17 1985-11-21 Dr. Karl Thomae Gmbh, 7950 Biberach Neue benzazepinderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE3631013A1 (de) * 1986-09-12 1988-03-24 Thomae Gmbh Dr K Neue naphthylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
JP2699511B2 (ja) * 1988-01-29 1998-01-19 武田薬品工業株式会社 置換アミン類
FR2868776B1 (fr) * 2004-04-13 2008-04-18 Servier Lab Nouveau procede de synthese de derives de la 1,3-dihydro- 2h-3-benzazepin-2-one, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3474090A (en) * 1966-12-22 1969-10-21 American Cyanamid Co 3-aminoalkyl-1,3-benzodiazepin-2-ones
US3780023A (en) * 1972-06-30 1973-12-18 J Suh 2-aralkylamino-4,5-dihydro-3h-1,3-benzodiazepines
US4210749A (en) * 1974-11-12 1980-07-01 Pennwalt Corporation Substituted 1,2,4,5-tetrahydro-3H,3 benzazepines
DE2639718C2 (de) * 1976-09-03 1987-03-05 Dr. Karl Thomae Gmbh, 7950 Biberach 1-[6,7-Dimethoxy-3,4-dihydro-2H-isochinolin-1-on-2-yl]-3-[N-methyl-N-(2-(3,4-dimethoxy-phenyl)-äthyl)-amino]-propan, dessen physiologisch verträgliche Säureadditionssalze und diese Verbindungen enthaltende Arzneimittel
IN156096B (ko) * 1981-03-19 1985-05-11 Usv Pharma Corp
DE3119874A1 (de) * 1981-05-19 1982-12-09 Dr. Karl Thomae Gmbh, 7950 Biberach "benzazepinderivate, ihre herstellung und ihre verwendung als arzneimittel"
DE3269625D1 (en) * 1981-08-11 1986-04-10 Ciba Geigy Ag Benzazepin-2-ones, process for their preparation, pharmaceutical preparations containing these compounds and the compounds for therapeutical use
JPS6436829A (en) * 1987-07-31 1989-02-07 Shinko Kinzoku Kogyo Kk Evacuation part washing apparatus

Also Published As

Publication number Publication date
DK527483A (da) 1984-05-19
DE3242599A1 (de) 1984-05-24
IE832692L (en) 1984-05-18
GB2130213A (en) 1984-05-31
GB2130213B (en) 1986-03-26
HU193189B (en) 1987-08-28
NZ206305A (en) 1986-10-08
AU568101B2 (en) 1987-12-17
PT77683A (de) 1983-12-01
ES527308A0 (es) 1985-01-01
JPH0441144B2 (ko) 1992-07-07
FI834174A0 (fi) 1983-11-15
PL139449B1 (en) 1987-01-31
IE56261B1 (en) 1991-06-05
EP0109636B1 (de) 1989-01-18
DE3378980D1 (en) 1989-02-23
NO834222L (no) 1984-05-21
PL244610A1 (en) 1985-07-16
DD215540A5 (de) 1984-11-14
ES8502689A1 (es) 1985-01-16
DK527483D0 (da) 1983-11-17
EP0109636A3 (en) 1985-11-21
FI834174A (fi) 1984-05-19
IL70258A (en) 1987-08-31
ATE40118T1 (de) 1989-02-15
IL70258A0 (en) 1984-02-29
ES8502424A1 (es) 1985-01-01
EP0109636A2 (de) 1984-05-30
PT77683B (de) 1986-05-12
ES532662A0 (es) 1985-01-16
JPS59106466A (ja) 1984-06-20
KR840006628A (ko) 1984-12-01
CA1211107A (en) 1986-09-09
GR81253B (ko) 1984-12-11
ZA838572B (en) 1985-07-31
AU2146183A (en) 1984-05-24
YU226283A (en) 1986-04-30
GB8330731D0 (en) 1983-12-29

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