CS228919B2 - Method of preparing halogenomethylester of 1,1-dioxide of penicillanic acid - Google Patents

Method of preparing halogenomethylester of 1,1-dioxide of penicillanic acid Download PDF

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Publication number
CS228919B2
CS228919B2 CS822013A CS201382A CS228919B2 CS 228919 B2 CS228919 B2 CS 228919B2 CS 822013 A CS822013 A CS 822013A CS 201382 A CS201382 A CS 201382A CS 228919 B2 CS228919 B2 CS 228919B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
acid
compound
dioxide
reaction
Prior art date
Application number
CS822013A
Other languages
Czech (cs)
English (en)
Inventor
Thomas Ch Crawford
Vytautas J Jasys
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to CS831015A priority Critical patent/CS228945B2/cs
Publication of CS228919B2 publication Critical patent/CS228919B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CS822013A 1981-03-23 1982-03-23 Method of preparing halogenomethylester of 1,1-dioxide of penicillanic acid CS228919B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CS831015A CS228945B2 (cs) 1981-03-23 1983-02-15 Způsob přípravy halogenmethylesterů 6-substituovaných nebo 6,6-d<§ubstituovaných 1,1-dfoxidft penicilanové kyseliny

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/246,453 US4419284A (en) 1981-03-23 1981-03-23 Preparation of halomethyl esters (and related esters) of penicillanic acid 1,1-dioxide

Publications (1)

Publication Number Publication Date
CS228919B2 true CS228919B2 (en) 1984-05-14

Family

ID=22930753

Family Applications (1)

Application Number Title Priority Date Filing Date
CS822013A CS228919B2 (en) 1981-03-23 1982-03-23 Method of preparing halogenomethylester of 1,1-dioxide of penicillanic acid

Country Status (19)

Country Link
US (1) US4419284A (fr)
EP (1) EP0061315A1 (fr)
JP (1) JPS57169486A (fr)
KR (1) KR830009112A (fr)
AR (1) AR231292A1 (fr)
AU (1) AU527896B2 (fr)
CS (1) CS228919B2 (fr)
DK (1) DK127082A (fr)
ES (2) ES8305767A1 (fr)
FI (1) FI820994L (fr)
GB (1) GB2095667A (fr)
GR (1) GR76480B (fr)
IL (1) IL65307A0 (fr)
NO (1) NO820899L (fr)
PH (1) PH17749A (fr)
PL (2) PL239642A1 (fr)
PT (1) PT74620B (fr)
YU (1) YU62082A (fr)
ZA (1) ZA821902B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT76526B (en) * 1982-04-19 1986-01-21 Gist Brocades Nv Preparation of 6-alpha-bromo- and/or 6,6-dibromopenicillanic acid 1,1-dioxides
US5266693A (en) * 1982-04-19 1993-11-30 Gist-Brocades N.V. 6-diazo-penicillanic acid 1,1-dioxide derivatives
PH20068A (en) * 1982-12-06 1986-09-18 Pfizer Process and intermediates for sultamicillin and analogs
EP0139048A1 (fr) * 1983-10-18 1985-05-02 Gist-Brocades N.V. Procédé de déhalogénation de 1,1-dioxyde d'acide 6,6-dibromopénicillanique
US5015473A (en) * 1984-01-30 1991-05-14 Pfizer Inc. 6-(substituted)methylenepenicillanic and 6-(substituted)hydroxymethylpenicillanic acids and derivatives thereof
US4826833A (en) * 1984-01-30 1989-05-02 Pfizer Inc. 6-(Substituted)methylene-penicillanic and 6-(substituted)hydroxymethylpenicillanic acids and derivatives thereof
EP0262202B1 (fr) * 1986-04-10 1992-07-01 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) Procede servant a preparer des derives d'acide penicillanique
KR910009271B1 (ko) * 1989-06-20 1991-11-08 김영설 1,1-디옥소페닐실라노일 옥시메틸 D-6-[α-(메틸렌아미노)페닐-아세트아미도]-페니실라네이트와 그의 파라-톨루엔술폰산염
ES2039299B1 (es) * 1991-10-04 1994-05-16 Asturpharma S A Procedimiento de obtencion de esteres de acido 1,1-dioxopenicilanico y sus sales.
ES2100125B1 (es) * 1995-06-02 1998-04-01 Asturpharma S A Procedimiento de preparacion de esteres de metanodiol de acido dioxopenicilanico.
IT202000031070A1 (it) 2020-12-16 2022-06-16 Paolo Bonomi Procedimento di sintesi di derivati ammidici dell’acido 8-idrossi penicillanico

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3996235A (en) * 1974-02-19 1976-12-07 Beecham Group Limited 6-Isocyanato-6-substituted penicillins
US4234579A (en) * 1977-06-07 1980-11-18 Pfizer Inc. Penicillanic acid 1,1-dioxides as β-lactamase inhibitors
IN149747B (fr) * 1977-06-07 1982-04-03 Pfizer
JPS6056160B2 (ja) * 1977-06-07 1985-12-09 フアイザ−・インコ−ポレ−テツド β−ラクタマ−ゼ阻害剤としてのペニシラン酸１，１−ジオキシド
US4224951A (en) * 1978-11-30 1980-09-30 Hasson Harrith M Gynecological instrument
US4203992A (en) * 1978-12-11 1980-05-20 E. R. Squibb & Sons, Inc. β-Bromopenicillanic acid sulfone
DE3068390D1 (en) * 1979-01-10 1984-08-09 Beecham Group Plc Penicillin derivatives, process for their preparation and pharmaceutical compositions containing certain of these compounds
JPS5598186A (en) * 1979-01-10 1980-07-25 Beecham Group Ltd Manufacture of penicillin derivative
IE49881B1 (en) 1979-02-13 1986-01-08 Leo Pharm Prod Ltd B-lactam intermediates
ZA80796B (en) * 1979-02-13 1981-02-25 Leo Pharm Prod Ltd Chemical compounds
SE449103B (sv) * 1979-03-05 1987-04-06 Pfizer Sett att framstella penicillansyra-1,1-dioxid samt estrar derav
ZA80646B (en) * 1979-03-05 1981-02-25 Pfizer Process and intermediates for penicillanic acid,1,1-dioxide and esters thereof

Also Published As

Publication number Publication date
IL65307A0 (en) 1982-05-31
ZA821902B (en) 1983-01-26
ES518969A0 (es) 1984-03-01
GR76480B (fr) 1984-08-10
AU527896B2 (en) 1983-03-31
PT74620B (en) 1984-11-26
PH17749A (en) 1984-11-27
ES510654A0 (es) 1983-04-16
FI820994L (fi) 1982-09-24
NO820899L (no) 1982-09-24
JPS57169486A (en) 1982-10-19
GB2095667A (en) 1982-10-06
PL235579A1 (en) 1983-06-06
ES8305767A1 (es) 1983-04-16
PL239642A1 (en) 1983-08-15
KR830009112A (ko) 1983-12-17
AR231292A1 (es) 1984-10-31
EP0061315A1 (fr) 1982-09-29
PT74620A (en) 1982-04-01
ES8403131A1 (es) 1984-03-01
AU8176382A (en) 1982-11-04
US4419284A (en) 1983-12-06
DK127082A (da) 1982-09-24
YU62082A (en) 1985-03-20

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