ES8403131A1 - Un procedimiento para la preparacion de derivados de 1,1-dioxido del acido penicilanico. - Google Patents
Un procedimiento para la preparacion de derivados de 1,1-dioxido del acido penicilanico.Info
- Publication number
- ES8403131A1 ES8403131A1 ES518969A ES518969A ES8403131A1 ES 8403131 A1 ES8403131 A1 ES 8403131A1 ES 518969 A ES518969 A ES 518969A ES 518969 A ES518969 A ES 518969A ES 8403131 A1 ES8403131 A1 ES 8403131A1
- Authority
- ES
- Spain
- Prior art keywords
- intermediates useful
- penicillanic acid
- dioxide derivatives
- certain intermediates
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE 1,1-DIOXIDO DEL ACIDO PENICILANICO, DE FORMULA GENERAL (I), EN LA QUE X ES CL, BR O I; Y Y Z SON CADA UNO DE ELLOS CL, BR O I.CONSISTE EN OXIDAR UN COMPUESTO DE FORMULA (II), EN LA QUE X, Y Y Z TIENEN LOS SIGNIFICADOS YA INDICADOS; Y M ES 0 O 1, CON UN AGENTE OXIDANTE.DE APLICACION COMO COMPUESTOS INTERMEDIOS EN LA PRODUCCION DE ANTIBIOTICOS CON ACTIVIDAD INHIBIDORA DE B-LACTAMASAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/246,453 US4419284A (en) | 1981-03-23 | 1981-03-23 | Preparation of halomethyl esters (and related esters) of penicillanic acid 1,1-dioxide |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8403131A1 true ES8403131A1 (es) | 1984-03-01 |
ES518969A0 ES518969A0 (es) | 1984-03-01 |
Family
ID=22930753
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES510654A Granted ES510654A0 (es) | 1981-03-23 | 1982-03-22 | Un procedimiento para la preparacion de derivados de 1,1-dioxido del acido penicilanico. |
ES518969A Granted ES518969A0 (es) | 1981-03-23 | 1983-01-13 | Un procedimiento para la preparacion de derivados de 1,1-dioxido del acido penicilanico. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES510654A Granted ES510654A0 (es) | 1981-03-23 | 1982-03-22 | Un procedimiento para la preparacion de derivados de 1,1-dioxido del acido penicilanico. |
Country Status (19)
Country | Link |
---|---|
US (1) | US4419284A (es) |
EP (1) | EP0061315A1 (es) |
JP (1) | JPS57169486A (es) |
KR (1) | KR830009112A (es) |
AR (1) | AR231292A1 (es) |
AU (1) | AU527896B2 (es) |
CS (1) | CS228919B2 (es) |
DK (1) | DK127082A (es) |
ES (2) | ES510654A0 (es) |
FI (1) | FI820994L (es) |
GB (1) | GB2095667A (es) |
GR (1) | GR76480B (es) |
IL (1) | IL65307A0 (es) |
NO (1) | NO820899L (es) |
PH (1) | PH17749A (es) |
PL (2) | PL235579A1 (es) |
PT (1) | PT74620B (es) |
YU (1) | YU62082A (es) |
ZA (1) | ZA821902B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT76526B (en) * | 1982-04-19 | 1986-01-21 | Gist Brocades Nv | Preparation of 6-alpha-bromo- and/or 6,6-dibromopenicillanic acid 1,1-dioxides |
US5266693A (en) * | 1982-04-19 | 1993-11-30 | Gist-Brocades N.V. | 6-diazo-penicillanic acid 1,1-dioxide derivatives |
PH20068A (en) * | 1982-12-06 | 1986-09-18 | Pfizer | Process and intermediates for sultamicillin and analogs |
EP0139048A1 (en) * | 1983-10-18 | 1985-05-02 | Gist-Brocades N.V. | Process for the dehalogenation of 6,6-dibromopenicillanic acid 1,1-dioxide |
US4826833A (en) * | 1984-01-30 | 1989-05-02 | Pfizer Inc. | 6-(Substituted)methylene-penicillanic and 6-(substituted)hydroxymethylpenicillanic acids and derivatives thereof |
US5015473A (en) * | 1984-01-30 | 1991-05-14 | Pfizer Inc. | 6-(substituted)methylenepenicillanic and 6-(substituted)hydroxymethylpenicillanic acids and derivatives thereof |
DE3780112T2 (de) * | 1986-04-10 | 1992-12-24 | Leo Pharm Prod Ltd | Verfahren zur herstellung von penicillansaeure-derivaten. |
KR910009271B1 (ko) * | 1989-06-20 | 1991-11-08 | 김영설 | 1,1-디옥소페닐실라노일 옥시메틸 D-6-[α-(메틸렌아미노)페닐-아세트아미도]-페니실라네이트와 그의 파라-톨루엔술폰산염 |
ES2039299B1 (es) * | 1991-10-04 | 1994-05-16 | Asturpharma S A | Procedimiento de obtencion de esteres de acido 1,1-dioxopenicilanico y sus sales. |
ES2100125B1 (es) * | 1995-06-02 | 1998-04-01 | Asturpharma S A | Procedimiento de preparacion de esteres de metanodiol de acido dioxopenicilanico. |
IT202000031070A1 (it) | 2020-12-16 | 2022-06-16 | Paolo Bonomi | Procedimento di sintesi di derivati ammidici dell’acido 8-idrossi penicillanico |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3996235A (en) * | 1974-02-19 | 1976-12-07 | Beecham Group Limited | 6-Isocyanato-6-substituted penicillins |
JPS6056160B2 (ja) * | 1977-06-07 | 1985-12-09 | フアイザ−・インコ−ポレ−テツド | β−ラクタマ−ゼ阻害剤としてのペニシラン酸1,1−ジオキシド |
US4234579A (en) * | 1977-06-07 | 1980-11-18 | Pfizer Inc. | Penicillanic acid 1,1-dioxides as β-lactamase inhibitors |
IN149747B (es) * | 1977-06-07 | 1982-04-03 | Pfizer | |
US4224951A (en) * | 1978-11-30 | 1980-09-30 | Hasson Harrith M | Gynecological instrument |
US4203992A (en) * | 1978-12-11 | 1980-05-20 | E. R. Squibb & Sons, Inc. | β-Bromopenicillanic acid sulfone |
DE3068390D1 (en) * | 1979-01-10 | 1984-08-09 | Beecham Group Plc | Penicillin derivatives, process for their preparation and pharmaceutical compositions containing certain of these compounds |
JPS5598186A (en) * | 1979-01-10 | 1980-07-25 | Beecham Group Ltd | Manufacture of penicillin derivative |
IE49881B1 (en) | 1979-02-13 | 1986-01-08 | Leo Pharm Prod Ltd | B-lactam intermediates |
ZA80796B (en) * | 1979-02-13 | 1981-02-25 | Leo Pharm Prod Ltd | Chemical compounds |
SE449103B (sv) * | 1979-03-05 | 1987-04-06 | Pfizer | Sett att framstella penicillansyra-1,1-dioxid samt estrar derav |
ZA80646B (en) | 1979-03-05 | 1981-02-25 | Pfizer | Process and intermediates for penicillanic acid,1,1-dioxide and esters thereof |
-
1981
- 1981-03-23 US US06/246,453 patent/US4419284A/en not_active Expired - Lifetime
-
1982
- 1982-03-18 NO NO820899A patent/NO820899L/no unknown
- 1982-03-18 GR GR67643A patent/GR76480B/el unknown
- 1982-03-19 EP EP82301416A patent/EP0061315A1/en not_active Withdrawn
- 1982-03-19 AR AR288809A patent/AR231292A1/es active
- 1982-03-19 GB GB8208061A patent/GB2095667A/en not_active Withdrawn
- 1982-03-22 ZA ZA821902A patent/ZA821902B/xx unknown
- 1982-03-22 AU AU81763/82A patent/AU527896B2/en not_active Ceased
- 1982-03-22 ES ES510654A patent/ES510654A0/es active Granted
- 1982-03-22 YU YU00620/82A patent/YU62082A/xx unknown
- 1982-03-22 KR KR1019820001222A patent/KR830009112A/ko unknown
- 1982-03-22 IL IL65307A patent/IL65307A0/xx unknown
- 1982-03-22 PH PH27040A patent/PH17749A/en unknown
- 1982-03-22 PT PT74620A patent/PT74620B/pt unknown
- 1982-03-22 FI FI820994A patent/FI820994L/fi not_active Application Discontinuation
- 1982-03-22 DK DK127082A patent/DK127082A/da not_active Application Discontinuation
- 1982-03-23 JP JP57046184A patent/JPS57169486A/ja active Pending
- 1982-03-23 PL PL23557982A patent/PL235579A1/xx unknown
- 1982-03-23 CS CS822013A patent/CS228919B2/cs unknown
- 1982-03-23 PL PL23964282A patent/PL239642A1/xx unknown
-
1983
- 1983-01-13 ES ES518969A patent/ES518969A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
GR76480B (es) | 1984-08-10 |
ES518969A0 (es) | 1984-03-01 |
ES8305767A1 (es) | 1983-04-16 |
DK127082A (da) | 1982-09-24 |
US4419284A (en) | 1983-12-06 |
PH17749A (en) | 1984-11-27 |
PT74620B (en) | 1984-11-26 |
AU527896B2 (en) | 1983-03-31 |
PL235579A1 (en) | 1983-06-06 |
PL239642A1 (en) | 1983-08-15 |
AU8176382A (en) | 1982-11-04 |
AR231292A1 (es) | 1984-10-31 |
JPS57169486A (en) | 1982-10-19 |
ES510654A0 (es) | 1983-04-16 |
NO820899L (no) | 1982-09-24 |
GB2095667A (en) | 1982-10-06 |
KR830009112A (ko) | 1983-12-17 |
PT74620A (en) | 1982-04-01 |
CS228919B2 (en) | 1984-05-14 |
EP0061315A1 (en) | 1982-09-29 |
YU62082A (en) | 1985-03-20 |
IL65307A0 (en) | 1982-05-31 |
FI820994L (fi) | 1982-09-24 |
ZA821902B (en) | 1983-01-26 |
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