JPS57169486A - Manufacture of halomethyl ester ( and related ester) of penicillanic acid 1,1-dioxide - Google Patents

Manufacture of halomethyl ester ( and related ester) of penicillanic acid 1,1-dioxide

Info

Publication number
JPS57169486A
JPS57169486A JP57046184A JP4618482A JPS57169486A JP S57169486 A JPS57169486 A JP S57169486A JP 57046184 A JP57046184 A JP 57046184A JP 4618482 A JP4618482 A JP 4618482A JP S57169486 A JPS57169486 A JP S57169486A
Authority
JP
Japan
Prior art keywords
ester
dioxide
manufacture
halomethyl
penicillanic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP57046184A
Other languages
English (en)
Inventor
Chiyaaruzu Kuroofuoodo Toomasu
Jiyon Jiyashisu Baitootasu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of JPS57169486A publication Critical patent/JPS57169486A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP57046184A 1981-03-23 1982-03-23 Manufacture of halomethyl ester ( and related ester) of penicillanic acid 1,1-dioxide Pending JPS57169486A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/246,453 US4419284A (en) 1981-03-23 1981-03-23 Preparation of halomethyl esters (and related esters) of penicillanic acid 1,1-dioxide

Publications (1)

Publication Number Publication Date
JPS57169486A true JPS57169486A (en) 1982-10-19

Family

ID=22930753

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57046184A Pending JPS57169486A (en) 1981-03-23 1982-03-23 Manufacture of halomethyl ester ( and related ester) of penicillanic acid 1,1-dioxide

Country Status (19)

Country Link
US (1) US4419284A (ja)
EP (1) EP0061315A1 (ja)
JP (1) JPS57169486A (ja)
KR (1) KR830009112A (ja)
AR (1) AR231292A1 (ja)
AU (1) AU527896B2 (ja)
CS (1) CS228919B2 (ja)
DK (1) DK127082A (ja)
ES (2) ES510654A0 (ja)
FI (1) FI820994L (ja)
GB (1) GB2095667A (ja)
GR (1) GR76480B (ja)
IL (1) IL65307A0 (ja)
NO (1) NO820899L (ja)
PH (1) PH17749A (ja)
PL (2) PL239642A1 (ja)
PT (1) PT74620B (ja)
YU (1) YU62082A (ja)
ZA (1) ZA821902B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59112992A (ja) * 1982-12-06 1984-06-29 フアイザ−・インコ−ポレ−テツド スルタミシリンおよび同族体類の製法

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT76526B (en) * 1982-04-19 1986-01-21 Gist Brocades Nv Preparation of 6-alpha-bromo- and/or 6,6-dibromopenicillanic acid 1,1-dioxides
US5266693A (en) * 1982-04-19 1993-11-30 Gist-Brocades N.V. 6-diazo-penicillanic acid 1,1-dioxide derivatives
EP0139048A1 (en) * 1983-10-18 1985-05-02 Gist-Brocades N.V. Process for the dehalogenation of 6,6-dibromopenicillanic acid 1,1-dioxide
US5015473A (en) * 1984-01-30 1991-05-14 Pfizer Inc. 6-(substituted)methylenepenicillanic and 6-(substituted)hydroxymethylpenicillanic acids and derivatives thereof
US4826833A (en) * 1984-01-30 1989-05-02 Pfizer Inc. 6-(Substituted)methylene-penicillanic and 6-(substituted)hydroxymethylpenicillanic acids and derivatives thereof
JPH07103129B2 (ja) * 1986-04-10 1995-11-08 レオ・ファーマシューティカル・プロダクツ・リミテッド・エイ／エス（レーベンス・ケミスケ・ファブリック・プロデュクチオンスアクチーセルスカブ） ペニシラン酸誘導体の改良された新規合成方法
KR910009271B1 (ko) * 1989-06-20 1991-11-08 김영설 1,1-디옥소페닐실라노일 옥시메틸 D-6-[α-(메틸렌아미노)페닐-아세트아미도]-페니실라네이트와 그의 파라-톨루엔술폰산염
ES2039299B1 (es) * 1991-10-04 1994-05-16 Asturpharma S A Procedimiento de obtencion de esteres de acido 1,1-dioxopenicilanico y sus sales.
ES2100125B1 (es) * 1995-06-02 1998-04-01 Asturpharma S A Procedimiento de preparacion de esteres de metanodiol de acido dioxopenicilanico.
IT202000031070A1 (it) 2020-12-16 2022-06-16 Paolo Bonomi Procedimento di sintesi di derivati ammidici dell’acido 8-idrossi penicillanico

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS543094A (en) * 1977-06-07 1979-01-11 Pfizer Penicillinic acid 1*11dioxide as betaalactamase inhibitor
JPS5598186A (en) * 1979-01-10 1980-07-25 Beecham Group Ltd Manufacture of penicillin derivative
JPS55113790A (en) * 1979-02-13 1980-09-02 Leo Pharm Prod Ltd Novel penicillanic ester derivative and its manufacture and use
JPS55120588A (en) * 1979-03-05 1980-09-17 Pfizer Penicillanic acid 1*11dioxide and manufacture and intermediate of same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3996235A (en) * 1974-02-19 1976-12-07 Beecham Group Limited 6-Isocyanato-6-substituted penicillins
IN149747B (ja) * 1977-06-07 1982-04-03 Pfizer
US4234579A (en) * 1977-06-07 1980-11-18 Pfizer Inc. Penicillanic acid 1,1-dioxides as β-lactamase inhibitors
US4224951A (en) * 1978-11-30 1980-09-30 Hasson Harrith M Gynecological instrument
US4203992A (en) * 1978-12-11 1980-05-20 E. R. Squibb & Sons, Inc. β-Bromopenicillanic acid sulfone
DE3068390D1 (en) * 1979-01-10 1984-08-09 Beecham Group Plc Penicillin derivatives, process for their preparation and pharmaceutical compositions containing certain of these compounds
IE49880B1 (en) 1979-02-13 1986-01-08 Leo Pharm Prod Ltd Penicillin derivatives
SE449103B (sv) * 1979-03-05 1987-04-06 Pfizer Sett att framstella penicillansyra-1,1-dioxid samt estrar derav

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS543094A (en) * 1977-06-07 1979-01-11 Pfizer Penicillinic acid 1*11dioxide as betaalactamase inhibitor
JPS5598186A (en) * 1979-01-10 1980-07-25 Beecham Group Ltd Manufacture of penicillin derivative
JPS55113790A (en) * 1979-02-13 1980-09-02 Leo Pharm Prod Ltd Novel penicillanic ester derivative and its manufacture and use
JPS55120588A (en) * 1979-03-05 1980-09-17 Pfizer Penicillanic acid 1*11dioxide and manufacture and intermediate of same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59112992A (ja) * 1982-12-06 1984-06-29 フアイザ−・インコ−ポレ−テツド スルタミシリンおよび同族体類の製法

Also Published As

Publication number Publication date
ZA821902B (en) 1983-01-26
GB2095667A (en) 1982-10-06
YU62082A (en) 1985-03-20
PL235579A1 (en) 1983-06-06
NO820899L (no) 1982-09-24
US4419284A (en) 1983-12-06
ES8305767A1 (es) 1983-04-16
PH17749A (en) 1984-11-27
KR830009112A (ko) 1983-12-17
EP0061315A1 (en) 1982-09-29
PT74620A (en) 1982-04-01
ES510654A0 (es) 1983-04-16
PL239642A1 (en) 1983-08-15
AR231292A1 (es) 1984-10-31
ES518969A0 (es) 1984-03-01
PT74620B (en) 1984-11-26
FI820994L (fi) 1982-09-24
AU8176382A (en) 1982-11-04
DK127082A (da) 1982-09-24
CS228919B2 (en) 1984-05-14
ES8403131A1 (es) 1984-03-01
AU527896B2 (en) 1983-03-31
IL65307A0 (en) 1982-05-31
GR76480B (ja) 1984-08-10

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