CS228909B2 - Method of preparing antibioticum a-4696 in complex form, or in the form of factor b1,b2,b3,c1a,c3 and e1 - Google Patents

Method of preparing antibioticum a-4696 in complex form, or in the form of factor b1,b2,b3,c1a,c3 and e1 Download PDF

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Publication number
CS228909B2
CS228909B2 CS819462A CS946281A CS228909B2 CS 228909 B2 CS228909 B2 CS 228909B2 CS 819462 A CS819462 A CS 819462A CS 946281 A CS946281 A CS 946281A CS 228909 B2 CS228909 B2 CS 228909B2
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CS
Czechoslovakia
Prior art keywords
antibiotic
pharmaceutically acceptable
factors
atcc
water
Prior art date
Application number
CS819462A
Other languages
Czech (cs)
English (en)
Inventor
Manuel Debono
Kurt E Merkel
Robert E Weeks
Herald J Cole
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Priority to CS824513A priority Critical patent/CS228936B2/cs
Publication of CS228909B2 publication Critical patent/CS228909B2/cs

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/045—Actinoplanes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/19—Antibiotic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Feed For Specific Animals (AREA)
  • Fodder In General (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CS819462A 1980-12-18 1981-12-17 Method of preparing antibioticum a-4696 in complex form, or in the form of factor b1,b2,b3,c1a,c3 and e1 CS228909B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CS824513A CS228936B2 (cs) 1980-12-18 1982-12-17 Předběžné, respektive doplňkové krmivo pra vytvoření krmivá pro hospodářská zvířata, zvláště přežvýkavco

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/217,962 US4322406A (en) 1980-12-18 1980-12-18 Antibiotic A-4696 factors B1, B2, B3, C1a, C3 and E1

Publications (1)

Publication Number Publication Date
CS228909B2 true CS228909B2 (en) 1984-05-14

Family

ID=22813191

Family Applications (1)

Application Number Title Priority Date Filing Date
CS819462A CS228909B2 (en) 1980-12-18 1981-12-17 Method of preparing antibioticum a-4696 in complex form, or in the form of factor b1,b2,b3,c1a,c3 and e1

Country Status (26)

Country Link
US (1) US4322406A (ko)
EP (1) EP0055070B1 (ko)
JP (1) JPS57132888A (ko)
KR (1) KR850001503B1 (ko)
AR (1) AR228377A1 (ko)
AT (1) ATE23192T1 (ko)
AU (1) AU547906B2 (ko)
CA (1) CA1171008A (ko)
CS (1) CS228909B2 (ko)
DD (2) DD202048A5 (ko)
DE (1) DE3175527D1 (ko)
DK (1) DK562281A (ko)
ES (1) ES508085A0 (ko)
FI (1) FI813958L (ko)
GB (1) GB2089814B (ko)
GR (1) GR77286B (ko)
HU (1) HU189548B (ko)
IE (1) IE51883B1 (ko)
IL (1) IL64485A (ko)
NZ (1) NZ199197A (ko)
PH (1) PH18801A (ko)
PL (1) PL134197B1 (ko)
PT (1) PT74137B (ko)
RO (1) RO82520A (ko)
YU (1) YU292881A (ko)
ZA (1) ZA818632B (ko)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR229888A1 (es) * 1982-03-24 1983-12-30 Lilly Co Eli Procedimiento para preparar el complejo antibiotico a41030 y sus factores a,b,c,d,e,f, y g
US4559323A (en) * 1982-03-24 1985-12-17 Eli Lilly And Company A41030 Antibiotics
US4537770A (en) * 1982-03-24 1985-08-27 Eli Lilly And Company A41030 antibiotics
US4713331A (en) * 1982-03-24 1987-12-15 Eli Lilly And Company Microbial production of A41030 antibiotics
US4604239A (en) * 1982-03-24 1986-08-05 Eli Lilly And Company Antibiotics
US4524135A (en) * 1982-05-21 1985-06-18 Eli Lilly And Company A-21978C cyclic peptides
IL68700A0 (en) * 1982-05-21 1983-09-30 Lilly Co Eli Improvements relating to a-21978c cyclic peptide derivatives and their production
US4462942A (en) * 1982-07-30 1984-07-31 Eli Lilly And Company A47934 Antibiotic and process for production thereof
RO87735A2 (ro) * 1982-12-20 1985-10-31 Eli Lilly And Co,Us Procedeu de obtinere a antibioticului a 51568 cu structura gliceproteica
US4558009A (en) * 1982-12-20 1985-12-10 Eli Lilly And Company Process for producing antibiotic A-51568 by fermentation and microorganism
US4479897A (en) * 1983-04-27 1984-10-30 Eli Lilly And Company Actaplanin antibiotics
US4672036A (en) * 1983-07-13 1987-06-09 Smithkline Beckman Corporation Pure cultures of Kibdelsporangium aridum Shearer gen. nov., sp. nov. ATCC 39323 and mutants thereof
US4548974A (en) * 1983-07-13 1985-10-22 Smithkline Beckman Corporation Antibiotics produced by Kibdelosporangium aridum shearer
US4537715A (en) * 1983-10-21 1985-08-27 Eli Lilly And Company Glycopeptide antibiotic CUC/CSV and process for its production
US4504467A (en) * 1983-10-21 1985-03-12 Eli Lilly And Company Glycopeptide derivatives
US4663282A (en) * 1983-10-21 1987-05-05 Eli Lilly And Company Glycopeptide antibiotic CUC/CSV and process for its production
US4563442A (en) * 1983-10-21 1986-01-07 Eli Lilly And Company Glycopeptide bioconversion products
US4587218A (en) * 1983-10-21 1986-05-06 Eli Lilly And Company Novel bioconverting microorganisms
US4497802A (en) * 1983-10-21 1985-02-05 Eli Lilly And Company N-Acyl glycopeptide derivatives
US4558008A (en) * 1983-12-13 1985-12-10 Eli Lilly And Company Process for production of A-51568B antibiotic
AU579120B2 (en) * 1983-12-16 1988-11-17 Gruppo Lepetit S.P.A. Chemical process for preparing antibiotic L 17392 (deglucoteicoplanin) and its salts
US4558036A (en) * 1984-02-17 1985-12-10 Eli Lilly And Company Actaplanin antibiotics
US4613503A (en) * 1984-10-11 1986-09-23 The Dow Chemical Company Antibiotic A26201-1 and antibiotic A26201-2 produced by a novel strain of actinoplanes
US4859599A (en) * 1984-10-11 1989-08-22 The Dow Chemical Company Antibiotic A26201-1 and antibiotic A26201-2 produced by a novel strain of actinoplanes
GB8608798D0 (en) * 1986-04-11 1986-05-14 Lepetit Spa Recovery of glycopeptide antibiotics from aqueous solutions
GB8624251D0 (en) * 1986-10-09 1986-11-12 Erba Farmitalia "1,2-beta-methylene-4-substituted androstene-3,17 dione derivatives
US4939244A (en) * 1987-01-30 1990-07-03 American Cyanamid Company Pseudoaglycones of LL-E33288 antibiotics
US4845194A (en) * 1987-02-27 1989-07-04 Eli Lilly And Company Glycopeptide recovery process
US4996148A (en) * 1987-07-13 1991-02-26 Eli Lilly And Company A80407 antibiotics
US5213797A (en) * 1987-07-13 1993-05-25 Eli Lilly And Company A80407 antibiotics

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3952095A (en) * 1972-06-02 1976-04-20 Eli Lilly And Company Novel antibiotic and a process for the production thereof
US4064233A (en) * 1974-12-17 1977-12-20 Eli Lilly And Company Antibiotic A-4696
US4115552A (en) * 1976-04-19 1978-09-19 Eli Lilly And Company Factor A and B of antibiotic A-4696
GB1578480A (en) * 1977-05-19 1980-11-05 Lilly Co Eli Antibiotic a-35512 and process for production thereof
GB2045231B (en) * 1979-04-07 1983-08-03 Lepetit Spa Antibiotic a/16686 and its preparation from actinoplanes
CA1170598A (en) * 1979-12-13 1984-07-10 Bernard J. Abbott Process for the preparation of cyclic peptide nuclei

Also Published As

Publication number Publication date
JPS57132888A (en) 1982-08-17
US4322406A (en) 1982-03-30
NZ199197A (en) 1984-11-09
IE812971L (en) 1982-06-18
DK562281A (da) 1982-06-19
GB2089814A (en) 1982-06-30
DE3175527D1 (en) 1986-12-04
GB2089814B (en) 1984-05-16
ES8304203A1 (es) 1983-02-16
ATE23192T1 (de) 1986-11-15
RO82520A (ro) 1983-09-26
PL234311A1 (ko) 1982-08-16
IE51883B1 (en) 1987-04-15
PH18801A (en) 1985-09-27
CA1171008A (en) 1984-07-17
AR228377A1 (es) 1983-02-28
ZA818632B (en) 1982-10-27
IL64485A0 (en) 1982-03-31
PT74137A (en) 1982-01-01
GR77286B (ko) 1984-09-11
KR830007832A (ko) 1983-11-07
YU292881A (en) 1983-10-31
PL134197B1 (en) 1985-07-31
DD204389A5 (de) 1983-11-30
FI813958L (fi) 1982-06-19
KR850001503B1 (ko) 1985-10-11
ES508085A0 (es) 1983-02-16
AU7859881A (en) 1982-06-24
DD202048A5 (de) 1983-08-24
PT74137B (en) 1984-05-09
HU189548B (en) 1986-07-28
IL64485A (en) 1985-01-31
RO82520B (ro) 1983-08-30
EP0055070A1 (en) 1982-06-30
EP0055070B1 (en) 1986-10-29
AU547906B2 (en) 1985-11-14

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CS228936B2 (cs) Předběžné, respektive doplňkové krmivo pra vytvoření krmivá pro hospodářská zvířata, zvláště přežvýkavco