CS219347B2 - Method of preparation of the 1-hydroxyaporfin derivative - Google Patents

Method of preparation of the 1-hydroxyaporfin derivative Download PDF

Info

Publication number
CS219347B2
CS219347B2 CS788858A CS885878A CS219347B2 CS 219347 B2 CS219347 B2 CS 219347B2 CS 788858 A CS788858 A CS 788858A CS 885878 A CS885878 A CS 885878A CS 219347 B2 CS219347 B2 CS 219347B2
Authority
CS
Czechoslovakia
Prior art keywords
carbon atoms
acid
reaction
preparation
tetrahydroisoquinoline
Prior art date
Application number
CS788858A
Other languages
Czech (cs)
English (en)
Inventor
Johannes Hartenstein
Gerhard Satzinger
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of CS219347B2 publication Critical patent/CS219347B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/18—Ring systems of four or more rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CS788858A 1977-12-22 1978-12-22 Method of preparation of the 1-hydroxyaporfin derivative CS219347B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2757281A DE2757281C3 (de) 1977-12-22 1977-12-22 Verfahren zur Herstellung von 1 -Hydroxy-Aporphinderivaten

Publications (1)

Publication Number Publication Date
CS219347B2 true CS219347B2 (en) 1983-03-25

Family

ID=6026893

Family Applications (1)

Application Number Title Priority Date Filing Date
CS788858A CS219347B2 (en) 1977-12-22 1978-12-22 Method of preparation of the 1-hydroxyaporfin derivative

Country Status (14)

Country Link
US (1) US4202980A (nl)
JP (1) JPS54119475A (nl)
BE (1) BE872842A (nl)
CH (1) CH637642A5 (nl)
CS (1) CS219347B2 (nl)
DD (1) DD139845A5 (nl)
DE (1) DE2757281C3 (nl)
FI (1) FI68223C (nl)
FR (1) FR2412534A1 (nl)
GB (1) GB2011393B (nl)
HU (1) HU178804B (nl)
IT (1) IT1110876B (nl)
NL (1) NL7812393A (nl)
SU (1) SU878194A3 (nl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5109136A (en) * 1990-08-09 1992-04-28 Warner-Lambert Company Tetracyclic amines useful as cerebrovascular agents
US6210680B1 (en) 1999-06-11 2001-04-03 Univera Pharmaceuticals, Inc. Method for the prevention and treatment of chronic venous insufficiency
TWI225397B (en) * 2000-05-04 2004-12-21 Nat Science Council Uses of thaliporphine or its derivatives in treatment of cardiac diseases and preparation of the same
US20030187011A1 (en) * 2001-12-20 2003-10-02 Lashuel Hilal A. Apomorphine inhibitors of amyloid-beta (Abeta) fibril formation and their use in amyloidosis based disease
TWI386396B (zh) * 2008-06-20 2013-02-21 Standard Chem & Pharm Co Ltd 阿朴芬化合物與含羧基藥劑之醫藥可接受鹽類及其製備方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950344A (en) * 1973-09-13 1976-04-13 The University Of Virginia Non-phenol oxidative coupling
DE2625116C2 (de) * 1976-06-04 1984-01-26 Gödecke AG, 1000 Berlin Verfahren zur Herstellung von 4-Hydroxy-aporphin-Derivaten

Also Published As

Publication number Publication date
US4202980A (en) 1980-05-13
HU178804B (en) 1982-06-28
FI68223C (fi) 1985-08-12
IT1110876B (it) 1986-01-06
FR2412534B1 (nl) 1983-05-20
BE872842A (fr) 1979-04-17
GB2011393A (en) 1979-07-11
DE2757281A1 (de) 1979-06-28
SU878194A3 (ru) 1981-10-30
DE2757281C3 (de) 1980-10-23
GB2011393B (en) 1982-05-06
DE2757281B2 (de) 1980-02-21
DD139845A5 (de) 1980-01-23
FI783971A (fi) 1979-06-23
CH637642A5 (de) 1983-08-15
NL7812393A (nl) 1979-06-26
JPS54119475A (en) 1979-09-17
IT7852364A0 (it) 1978-12-19
FR2412534A1 (fr) 1979-07-20
FI68223B (fi) 1985-04-30

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