CS214841B2 - Method of making the tetrahydrochinolines - Google Patents

Method of making the tetrahydrochinolines Download PDF

Info

Publication number
CS214841B2
CS214841B2 CS805832A CS583280A CS214841B2 CS 214841 B2 CS214841 B2 CS 214841B2 CS 805832 A CS805832 A CS 805832A CS 583280 A CS583280 A CS 583280A CS 214841 B2 CS214841 B2 CS 214841B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
compound
acid
carbon atoms
alkyl
Prior art date
Application number
CS805832A
Other languages
Czech (cs)
English (en)
Inventor
Otto Graewinger
Thomas Raabe
Rudi Beyerle
Josef Scholtholt
Rolf-Eberhard Nitz
Original Assignee
Cassella Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cassella Ag filed Critical Cassella Ag
Publication of CS214841B2 publication Critical patent/CS214841B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
CS805832A 1979-08-28 1980-08-26 Method of making the tetrahydrochinolines CS214841B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792934609 DE2934609A1 (de) 1979-08-28 1979-08-28 Tetrahydrochinolinderivate, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische zubereitungen.

Publications (1)

Publication Number Publication Date
CS214841B2 true CS214841B2 (en) 1982-06-25

Family

ID=6079411

Family Applications (1)

Application Number Title Priority Date Filing Date
CS805832A CS214841B2 (en) 1979-08-28 1980-08-26 Method of making the tetrahydrochinolines

Country Status (26)

Country Link
US (1) US4335123A (no)
EP (1) EP0025864B1 (no)
JP (1) JPS5634668A (no)
AR (1) AR226705A1 (no)
AT (1) ATE3422T1 (no)
AU (1) AU533484B2 (no)
BG (1) BG37994A3 (no)
CA (1) CA1154015A (no)
CS (1) CS214841B2 (no)
DD (1) DD153368A5 (no)
DE (2) DE2934609A1 (no)
DK (1) DK152754C (no)
ES (1) ES8106297A1 (no)
FI (1) FI802562A7 (no)
GR (1) GR69863B (no)
HU (1) HU180607B (no)
IE (1) IE50502B1 (no)
IL (1) IL60927A (no)
MX (1) MX6971E (no)
NO (1) NO154088C (no)
NZ (1) NZ194770A (no)
PH (1) PH16625A (no)
PL (1) PL124596B1 (no)
PT (1) PT71741B (no)
SU (1) SU965354A3 (no)
ZA (1) ZA805311B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5965076A (ja) * 1982-10-05 1984-04-13 Kowa Co 新規なキノリン誘導体
US4843082A (en) * 1986-05-05 1989-06-27 E. R. Squibb & Sons, Inc. 1,2,3,4-tetrahydro-8-quinolinol derivatives and anti-allergic use thereof
DE3633977A1 (de) * 1986-10-06 1988-04-07 Cassella Ag Tetrahydrochinolinderivate, ein verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische zubereitungen
WO1991005549A1 (en) * 1989-10-20 1991-05-02 Otsuka Pharmaceutical Co., Ltd. Benzoheterocyclic compounds
US7229986B2 (en) 2000-05-16 2007-06-12 Takeda Pharmaceutical Company Ltd. Melanin-concentrating hormone antagonist
IL153424A0 (en) * 2000-06-28 2003-07-06 Syngenta Participations Ag Process for the preparation of quinoline derivatives
AR051780A1 (es) * 2004-11-29 2007-02-07 Japan Tobacco Inc Compuestos en anillo fusionados que contienen nitrogeno y utilizacion de los mismos
WO2021116487A1 (en) 2019-12-13 2021-06-17 Som Innovation Biotech, S.A. Compounds for use in the treatment of niemann-pick c disease

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1198123A (fr) 1958-06-02 1959-12-04 Rech S Biolog Soc D Procédé de préparation d'aryloxy-amino-alcools et de leurs dérivés (sels, esters, ammoniums quaternaires) et produits obtenus par la mise en oeuvre de ce procédé
US3056792A (en) * 1958-06-04 1962-10-02 Geschickter Fund Med Res Unsymmetrical 1, 3-diamino-2-propanols
NL148312B (nl) * 1965-03-10 1976-01-15 Pfizer Werkwijze voor het bereiden van een geneesmiddel dat een of een aantal 1-chinolyl-2-alkylaminoethanolderivaten en/of de zuuradditiezouten daarvan bevat en de onder toepassing van deze werkwijze verkregen gevormde geneesmiddelen, alsmede werkwijze voor het bereiden van deze geneeskrachtige derivaten en de zuuradditiezouten daarvan.
JPS5239035B2 (no) 1972-12-14 1977-10-03
JPS5253868A (en) * 1975-10-25 1977-04-30 Tanabe Seiyaku Co Ltd Process for preparing aminopropanol derivative

Also Published As

Publication number Publication date
PH16625A (en) 1983-12-05
PT71741B (de) 1981-06-15
IE50502B1 (en) 1986-04-30
IE801799L (en) 1981-02-28
EP0025864A1 (de) 1981-04-01
NZ194770A (en) 1982-03-23
AU533484B2 (en) 1983-11-24
DE3063335D1 (en) 1983-07-07
ES494535A0 (es) 1981-08-01
MX6971E (es) 1987-01-09
FI802562A7 (fi) 1981-01-01
PT71741A (de) 1980-09-01
SU965354A3 (ru) 1982-10-07
BG37994A3 (bg) 1985-09-16
AR226705A1 (es) 1982-08-13
ES8106297A1 (es) 1981-08-01
JPS5634668A (en) 1981-04-06
DK351880A (da) 1981-03-01
US4335123A (en) 1982-06-15
NO154088B (no) 1986-04-07
AU6179380A (en) 1981-03-05
GR69863B (no) 1982-07-19
NO154088C (no) 1986-07-16
DK152754B (da) 1988-05-09
DK152754C (da) 1988-10-24
PL124596B1 (en) 1983-02-28
ZA805311B (en) 1981-08-26
ATE3422T1 (de) 1983-06-15
CA1154015A (en) 1983-09-20
IL60927A (en) 1984-04-30
EP0025864B1 (de) 1983-05-18
NO802435L (no) 1981-03-02
HU180607B (en) 1983-03-28
DE2934609A1 (de) 1981-03-12
DD153368A5 (de) 1982-01-06
PL226434A1 (no) 1981-04-24
IL60927A0 (en) 1980-10-26

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