ES8106297A1 - Procedimiento para la obtencion de derivados de la tetrahi- droquinolina - Google Patents
Procedimiento para la obtencion de derivados de la tetrahi- droquinolinaInfo
- Publication number
- ES8106297A1 ES8106297A1 ES494535A ES494535A ES8106297A1 ES 8106297 A1 ES8106297 A1 ES 8106297A1 ES 494535 A ES494535 A ES 494535A ES 494535 A ES494535 A ES 494535A ES 8106297 A1 ES8106297 A1 ES 8106297A1
- Authority
- ES
- Spain
- Prior art keywords
- processes
- production
- pharmaceutical preparations
- acyl
- preparations containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE DERIVADOS DE LA TETRAHIDROQUINOLINA DE FORMULA (I), DONDE R1 ES ALQUILO, FENILO, FENILO SUSTITUIDO O HETARILO; R2 Y R3 O SON HIDROGENO O ALQUILO HASTA DE CUATRO CARBONOS O FORMAN UN ANILLO HETEROCICLICO. SE HACE REACCIONAR EN UN DISOLVENTE O DISPERSANTE, A TEMPERATURA DE 20 GC HASTA LA TEMPERATURA DE REFLUJO DEL DISOLVENTE, UN COMPUESTO DE FORMULA (II), DONDE Z ES UN RADICAL DE FORMULA (III) O (IV) Y HAL ES HALOGENO, CON UNA AMINA DE FORMULA (V). OPCIONALMENTE EL COMPUESTO OBTENIDO SE HACE REACCIONAR CON UN ACIDO, EN PRESENCIA DE UN DILUYENTE, PARA FORMAR LA SAL DE ADICION DE ACIDO. DE APLICACION EN EL TRATAMIENTO DE AFECCIONES Y ENFERMEDADES CARDIACAS. *FORMULA*
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19792934609 DE2934609A1 (de) | 1979-08-28 | 1979-08-28 | Tetrahydrochinolinderivate, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische zubereitungen. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8106297A1 true ES8106297A1 (es) | 1981-08-01 |
ES494535A0 ES494535A0 (es) | 1981-08-01 |
Family
ID=6079411
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES494535A Granted ES494535A0 (es) | 1979-08-28 | 1980-08-27 | Procedimiento para la obtencion de derivados de la tetrahi- droquinolina |
Country Status (26)
Country | Link |
---|---|
US (1) | US4335123A (es) |
EP (1) | EP0025864B1 (es) |
JP (1) | JPS5634668A (es) |
AR (1) | AR226705A1 (es) |
AT (1) | ATE3422T1 (es) |
AU (1) | AU533484B2 (es) |
BG (1) | BG37994A3 (es) |
CA (1) | CA1154015A (es) |
CS (1) | CS214841B2 (es) |
DD (1) | DD153368A5 (es) |
DE (2) | DE2934609A1 (es) |
DK (1) | DK152754C (es) |
ES (1) | ES494535A0 (es) |
FI (1) | FI802562A (es) |
GR (1) | GR69863B (es) |
HU (1) | HU180607B (es) |
IE (1) | IE50502B1 (es) |
IL (1) | IL60927A (es) |
MX (1) | MX6971E (es) |
NO (1) | NO154088C (es) |
NZ (1) | NZ194770A (es) |
PH (1) | PH16625A (es) |
PL (1) | PL124596B1 (es) |
PT (1) | PT71741B (es) |
SU (1) | SU965354A3 (es) |
ZA (1) | ZA805311B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5965076A (ja) * | 1982-10-05 | 1984-04-13 | Kowa Co | 新規なキノリン誘導体 |
US4843082A (en) * | 1986-05-05 | 1989-06-27 | E. R. Squibb & Sons, Inc. | 1,2,3,4-tetrahydro-8-quinolinol derivatives and anti-allergic use thereof |
DE3633977A1 (de) * | 1986-10-06 | 1988-04-07 | Cassella Ag | Tetrahydrochinolinderivate, ein verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische zubereitungen |
ES2089033T3 (es) * | 1989-10-20 | 1996-10-01 | Otsuka Pharma Co Ltd | Compuestos benzoheterociclicos. |
US7229986B2 (en) | 2000-05-16 | 2007-06-12 | Takeda Pharmaceutical Company Ltd. | Melanin-concentrating hormone antagonist |
AR051780A1 (es) * | 2004-11-29 | 2007-02-07 | Japan Tobacco Inc | Compuestos en anillo fusionados que contienen nitrogeno y utilizacion de los mismos |
WO2021116487A1 (en) | 2019-12-13 | 2021-06-17 | Som Innovation Biotech, S.A. | Compounds for use in the treatment of niemann-pick c disease |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1198123A (fr) | 1958-06-02 | 1959-12-04 | Rech S Biolog Soc D | Procédé de préparation d'aryloxy-amino-alcools et de leurs dérivés (sels, esters, ammoniums quaternaires) et produits obtenus par la mise en oeuvre de ce procédé |
US3056792A (en) * | 1958-06-04 | 1962-10-02 | Geschickter Fund Med Res | Unsymmetrical 1, 3-diamino-2-propanols |
NL148312B (nl) * | 1965-03-10 | 1976-01-15 | Pfizer | Werkwijze voor het bereiden van een geneesmiddel dat een of een aantal 1-chinolyl-2-alkylaminoethanolderivaten en/of de zuuradditiezouten daarvan bevat en de onder toepassing van deze werkwijze verkregen gevormde geneesmiddelen, alsmede werkwijze voor het bereiden van deze geneeskrachtige derivaten en de zuuradditiezouten daarvan. |
JPS5239035B2 (es) | 1972-12-14 | 1977-10-03 | ||
JPS5253868A (en) * | 1975-10-25 | 1977-04-30 | Tanabe Seiyaku Co Ltd | Process for preparing aminopropanol derivative |
-
1979
- 1979-08-28 DE DE19792934609 patent/DE2934609A1/de not_active Withdrawn
-
1980
- 1980-08-14 DK DK351880A patent/DK152754C/da not_active IP Right Cessation
- 1980-08-14 FI FI802562A patent/FI802562A/fi not_active Application Discontinuation
- 1980-08-14 NO NO802435A patent/NO154088C/no unknown
- 1980-08-15 US US06/178,475 patent/US4335123A/en not_active Expired - Lifetime
- 1980-08-16 EP EP80104863A patent/EP0025864B1/de not_active Expired
- 1980-08-16 AT AT80104863T patent/ATE3422T1/de not_active IP Right Cessation
- 1980-08-16 DE DE8080104863T patent/DE3063335D1/de not_active Expired
- 1980-08-25 HU HU80802100A patent/HU180607B/hu not_active IP Right Cessation
- 1980-08-25 DD DD80223485A patent/DD153368A5/de unknown
- 1980-08-26 PT PT71741A patent/PT71741B/pt unknown
- 1980-08-26 SU SU802968607A patent/SU965354A3/ru active
- 1980-08-26 CS CS805832A patent/CS214841B2/cs unknown
- 1980-08-26 NZ NZ194770A patent/NZ194770A/xx unknown
- 1980-08-26 BG BG8048924A patent/BG37994A3/xx unknown
- 1980-08-26 GR GR62749A patent/GR69863B/el unknown
- 1980-08-27 CA CA000359140A patent/CA1154015A/en not_active Expired
- 1980-08-27 AU AU61793/80A patent/AU533484B2/en not_active Ceased
- 1980-08-27 ES ES494535A patent/ES494535A0/es active Granted
- 1980-08-27 IL IL60927A patent/IL60927A/xx unknown
- 1980-08-27 IE IE1799/80A patent/IE50502B1/en unknown
- 1980-08-27 JP JP11717680A patent/JPS5634668A/ja active Pending
- 1980-08-27 PL PL1980226434A patent/PL124596B1/pl unknown
- 1980-08-27 AR AR282318A patent/AR226705A1/es active
- 1980-08-27 ZA ZA00805311A patent/ZA805311B/xx unknown
- 1980-08-27 PH PH24500A patent/PH16625A/en unknown
- 1980-08-28 MX MX808999U patent/MX6971E/es unknown
Also Published As
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