CS212776B2 - Method of preparing a-30912 antibiotics - Google Patents
Method of preparing a-30912 antibiotics Download PDFInfo
- Publication number
- CS212776B2 CS212776B2 CS766294A CS629476A CS212776B2 CS 212776 B2 CS212776 B2 CS 212776B2 CS 766294 A CS766294 A CS 766294A CS 629476 A CS629476 A CS 629476A CS 212776 B2 CS212776 B2 CS 212776B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- antibiotic
- mixture
- factor
- methanol
- diethyl ether
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 17
- 239000003242 anti bacterial agent Substances 0.000 title description 6
- 229940088710 antibiotic agent Drugs 0.000 title 1
- 230000003115 biocidal effect Effects 0.000 claims abstract description 88
- 239000000203 mixture Substances 0.000 claims abstract description 63
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 18
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 10
- 241000133685 Aspergillus rugulosus Species 0.000 claims abstract description 9
- 150000003839 salts Chemical class 0.000 claims abstract description 5
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 129
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 81
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- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims description 18
- 229910052799 carbon Inorganic materials 0.000 claims description 17
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims description 16
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Compounds Of Unknown Constitution (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61910775A | 1975-10-02 | 1975-10-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS212776B2 true CS212776B2 (en) | 1982-03-26 |
Family
ID=24480483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS766294A CS212776B2 (en) | 1975-10-02 | 1976-09-29 | Method of preparing a-30912 antibiotics |
Country Status (28)
| Country | Link |
|---|---|
| JP (1) | JPS5242801A (ro) |
| AR (1) | AR209993A1 (ro) |
| AT (1) | AT346479B (ro) |
| AU (1) | AU506777B2 (ro) |
| BE (1) | BE846829A (ro) |
| BG (1) | BG25380A3 (ro) |
| CA (1) | CA1080145A (ro) |
| CH (1) | CH629531A5 (ro) |
| CS (1) | CS212776B2 (ro) |
| DD (1) | DD127442A5 (ro) |
| DE (1) | DE2643485A1 (ro) |
| DK (1) | DK143608C (ro) |
| ES (1) | ES452021A1 (ro) |
| FR (1) | FR2326200A1 (ro) |
| GB (2) | GB1499710A (ro) |
| GR (1) | GR61730B (ro) |
| HU (1) | HU173445B (ro) |
| IE (1) | IE43663B1 (ro) |
| IL (1) | IL50429A (ro) |
| NL (1) | NL7610808A (ro) |
| NZ (1) | NZ182123A (ro) |
| PL (1) | PL103996B1 (ro) |
| PT (1) | PT65617B (ro) |
| RO (1) | RO69985A (ro) |
| SE (1) | SE7610943L (ro) |
| SU (1) | SU620215A3 (ro) |
| YU (1) | YU236076A (ro) |
| ZA (1) | ZA765320B (ro) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5452797A (en) * | 1977-10-04 | 1979-04-25 | Meiji Seika Kaisha Ltd | Novel antibiotic substance bn-200, and its preparation |
| CA1170598A (en) * | 1979-12-13 | 1984-07-10 | Bernard J. Abbott | Process for the preparation of cyclic peptide nuclei |
| GB2180464A (en) * | 1985-09-18 | 1987-04-01 | British Gas Corp | Gas-solid phase reactions and apparatus therefor |
| FI76004B (fi) * | 1986-03-24 | 1988-05-31 | Seppo Kalervo Ruottu | Cirkulationsmassareaktor. |
-
1976
- 1976-09-06 IE IE1974/76A patent/IE43663B1/en unknown
- 1976-09-07 ZA ZA00765320A patent/ZA765320B/xx unknown
- 1976-09-08 IL IL50429A patent/IL50429A/xx unknown
- 1976-09-16 GR GR51709A patent/GR61730B/el unknown
- 1976-09-20 CA CA261,528A patent/CA1080145A/en not_active Expired
- 1976-09-21 PT PT65617A patent/PT65617B/pt unknown
- 1976-09-21 NZ NZ182123A patent/NZ182123A/xx unknown
- 1976-09-22 JP JP51114357A patent/JPS5242801A/ja active Pending
- 1976-09-23 AU AU18080/76A patent/AU506777B2/en not_active Expired
- 1976-09-23 GB GB39477/76A patent/GB1499710A/en not_active Expired
- 1976-09-24 BG BG034273A patent/BG25380A3/xx unknown
- 1976-09-27 DE DE19762643485 patent/DE2643485A1/de not_active Withdrawn
- 1976-09-27 GB GB39954/76A patent/GB1565821A/en not_active Expired
- 1976-09-27 YU YU02360/76A patent/YU236076A/xx unknown
- 1976-09-29 SU SU762404253A patent/SU620215A3/ru active
- 1976-09-29 CS CS766294A patent/CS212776B2/cs unknown
- 1976-09-29 NL NL7610808A patent/NL7610808A/xx not_active Application Discontinuation
- 1976-09-30 DK DK440276A patent/DK143608C/da active
- 1976-09-30 CH CH1241376A patent/CH629531A5/de not_active IP Right Cessation
- 1976-09-30 ES ES452021A patent/ES452021A1/es not_active Expired
- 1976-10-01 AT AT730976A patent/AT346479B/de not_active IP Right Cessation
- 1976-10-01 PL PL1976192798A patent/PL103996B1/pl unknown
- 1976-10-01 BE BE1007661A patent/BE846829A/xx unknown
- 1976-10-01 HU HU76EI703A patent/HU173445B/hu unknown
- 1976-10-01 AR AR264953A patent/AR209993A1/es active
- 1976-10-01 DD DD195092A patent/DD127442A5/xx unknown
- 1976-10-01 FR FR7629604A patent/FR2326200A1/fr active Granted
- 1976-10-01 SE SE7610943A patent/SE7610943L/ not_active Application Discontinuation
- 1976-10-02 RO RO7687891A patent/RO69985A/ro unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU506777B2 (en) | 1980-01-24 |
| IL50429A (en) | 1979-11-30 |
| AR209993A1 (es) | 1977-06-15 |
| NZ182123A (en) | 1978-06-02 |
| GR61730B (en) | 1978-12-30 |
| AU1808076A (en) | 1978-04-06 |
| CH629531A5 (en) | 1982-04-30 |
| IE43663L (en) | 1977-04-02 |
| DE2643485A1 (de) | 1977-04-14 |
| NL7610808A (nl) | 1977-04-05 |
| AT346479B (de) | 1978-11-10 |
| ZA765320B (en) | 1978-04-26 |
| RO69985A (ro) | 1981-05-15 |
| DK143608B (da) | 1981-09-14 |
| ES452021A1 (es) | 1977-12-01 |
| YU236076A (en) | 1983-04-30 |
| BG25380A3 (en) | 1978-09-15 |
| DK440276A (da) | 1977-04-03 |
| PL103996B1 (pl) | 1979-07-31 |
| ATA730976A (de) | 1978-03-15 |
| DD127442A5 (ro) | 1977-09-21 |
| DK143608C (da) | 1982-02-15 |
| GB1565821A (en) | 1980-04-23 |
| PT65617A (en) | 1976-10-01 |
| PT65617B (en) | 1978-04-05 |
| FR2326200B1 (ro) | 1980-03-07 |
| IL50429A0 (en) | 1976-11-30 |
| CA1080145A (en) | 1980-06-24 |
| HU173445B (hu) | 1979-05-28 |
| SU620215A3 (ru) | 1978-08-15 |
| JPS5242801A (en) | 1977-04-04 |
| IE43663B1 (en) | 1981-04-22 |
| GB1499710A (en) | 1978-02-01 |
| BE846829A (fr) | 1977-04-01 |
| FR2326200A1 (fr) | 1977-04-29 |
| SE7610943L (sv) | 1977-04-03 |
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