IE43663L - Antibiotic a-30912 mixture from aspergillus migulosus¹nrrl-8113. - Google Patents

Antibiotic a-30912 mixture from aspergillus migulosus¹nrrl-8113.

Info

Publication number
IE43663L
IE43663L IE761974A IE197476A IE43663L IE 43663 L IE43663 L IE 43663L IE 761974 A IE761974 A IE 761974A IE 197476 A IE197476 A IE 197476A IE 43663 L IE43663 L IE 43663L
Authority
IE
Ireland
Prior art keywords
antibiotic
mixture
factors
isolated
aspergillus
Prior art date
Application number
IE761974A
Other versions
IE43663B1 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IE43663L publication Critical patent/IE43663L/en
Publication of IE43663B1 publication Critical patent/IE43663B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

A process for the preparation of the antibiotic A-30912 mixture which contains the seven factors A, B, C, D, E, F and G is described. This antibiotic mixture is obtained by cultivating an Aspergillus rugulosus which has the deposition number NRRL 8113 under aerobic submerged fermentation conditions in a nutrient medium which contains substances providing assimilable carbohydrates, nitrogen and inorganic salts. As soon as a significant antibiotic activity has formed, the antibiotic mixture is isolated from the fermentation medium. Each of the 7 factors A to G can be isolated individually from this antibiotic A-30912 mixture. The antibiotic A-30912 mixture and the individual factors contained therein have antifungal activity and they can be employed, in particular, as active substances in compositions for controlling fungal diseases of the skin. [GB1499710A]
IE1974/76A 1975-10-02 1976-09-06 Antibiotic and process for production thereof IE43663B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61910775A 1975-10-02 1975-10-02

Publications (2)

Publication Number Publication Date
IE43663L true IE43663L (en) 1977-04-02
IE43663B1 IE43663B1 (en) 1981-04-22

Family

ID=24480483

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1974/76A IE43663B1 (en) 1975-10-02 1976-09-06 Antibiotic and process for production thereof

Country Status (28)

Country Link
JP (1) JPS5242801A (en)
AR (1) AR209993A1 (en)
AT (1) AT346479B (en)
AU (1) AU506777B2 (en)
BE (1) BE846829A (en)
BG (1) BG25380A3 (en)
CA (1) CA1080145A (en)
CH (1) CH629531A5 (en)
CS (1) CS212776B2 (en)
DD (1) DD127442A5 (en)
DE (1) DE2643485A1 (en)
DK (1) DK143608C (en)
ES (1) ES452021A1 (en)
FR (1) FR2326200A1 (en)
GB (2) GB1499710A (en)
GR (1) GR61730B (en)
HU (1) HU173445B (en)
IE (1) IE43663B1 (en)
IL (1) IL50429A (en)
NL (1) NL7610808A (en)
NZ (1) NZ182123A (en)
PL (1) PL103996B1 (en)
PT (1) PT65617B (en)
RO (1) RO69985A (en)
SE (1) SE7610943L (en)
SU (1) SU620215A3 (en)
YU (1) YU236076A (en)
ZA (1) ZA765320B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5452797A (en) * 1977-10-04 1979-04-25 Meiji Seika Kaisha Ltd Novel antibiotic substance bn-200, and its preparation
CA1170598A (en) * 1979-12-13 1984-07-10 Bernard J. Abbott Process for the preparation of cyclic peptide nuclei
GB2180464A (en) * 1985-09-18 1987-04-01 British Gas Corp Gas-solid phase reactions and apparatus therefor
FI76004B (en) * 1986-03-24 1988-05-31 Seppo Kalervo Ruottu CIRKULATIONSMASSAREAKTOR.

Also Published As

Publication number Publication date
CS212776B2 (en) 1982-03-26
SE7610943L (en) 1977-04-03
BE846829A (en) 1977-04-01
AU1808076A (en) 1978-04-06
SU620215A3 (en) 1978-08-15
JPS5242801A (en) 1977-04-04
IL50429A (en) 1979-11-30
PL103996B1 (en) 1979-07-31
IE43663B1 (en) 1981-04-22
CH629531A5 (en) 1982-04-30
NZ182123A (en) 1978-06-02
RO69985A (en) 1981-05-15
BG25380A3 (en) 1978-09-15
PT65617A (en) 1976-10-01
HU173445B (en) 1979-05-28
AU506777B2 (en) 1980-01-24
DD127442A5 (en) 1977-09-21
ATA730976A (en) 1978-03-15
GB1499710A (en) 1978-02-01
DK143608B (en) 1981-09-14
PT65617B (en) 1978-04-05
FR2326200B1 (en) 1980-03-07
FR2326200A1 (en) 1977-04-29
ZA765320B (en) 1978-04-26
DE2643485A1 (en) 1977-04-14
AT346479B (en) 1978-11-10
AR209993A1 (en) 1977-06-15
NL7610808A (en) 1977-04-05
DK440276A (en) 1977-04-03
ES452021A1 (en) 1977-12-01
YU236076A (en) 1983-04-30
DK143608C (en) 1982-02-15
CA1080145A (en) 1980-06-24
IL50429A0 (en) 1976-11-30
GB1565821A (en) 1980-04-23
GR61730B (en) 1978-12-30

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