SE7610943L - PROCEDURE FOR PREPARING A NEW ANTIBIOTIC CALLED A-30912 - Google Patents

PROCEDURE FOR PREPARING A NEW ANTIBIOTIC CALLED A-30912

Info

Publication number
SE7610943L
SE7610943L SE7610943A SE7610943A SE7610943L SE 7610943 L SE7610943 L SE 7610943L SE 7610943 A SE7610943 A SE 7610943A SE 7610943 A SE7610943 A SE 7610943A SE 7610943 L SE7610943 L SE 7610943L
Authority
SE
Sweden
Prior art keywords
antibiotic
mixture
factors
preparing
procedure
Prior art date
Application number
SE7610943A
Other languages
Unknown language ( )
Swedish (sv)
Inventor
M M Hoehn
K H Michel
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SE7610943L publication Critical patent/SE7610943L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A process for the preparation of the antibiotic A-30912 mixture which contains the seven factors A, B, C, D, E, F and G is described. This antibiotic mixture is obtained by cultivating an Aspergillus rugulosus which has the deposition number NRRL 8113 under aerobic submerged fermentation conditions in a nutrient medium which contains substances providing assimilable carbohydrates, nitrogen and inorganic salts. As soon as a significant antibiotic activity has formed, the antibiotic mixture is isolated from the fermentation medium. Each of the 7 factors A to G can be isolated individually from this antibiotic A-30912 mixture. The antibiotic A-30912 mixture and the individual factors contained therein have antifungal activity and they can be employed, in particular, as active substances in compositions for controlling fungal diseases of the skin.
SE7610943A 1975-10-02 1976-10-01 PROCEDURE FOR PREPARING A NEW ANTIBIOTIC CALLED A-30912 SE7610943L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61910775A 1975-10-02 1975-10-02

Publications (1)

Publication Number Publication Date
SE7610943L true SE7610943L (en) 1977-04-03

Family

ID=24480483

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7610943A SE7610943L (en) 1975-10-02 1976-10-01 PROCEDURE FOR PREPARING A NEW ANTIBIOTIC CALLED A-30912

Country Status (28)

Country Link
JP (1) JPS5242801A (en)
AR (1) AR209993A1 (en)
AT (1) AT346479B (en)
AU (1) AU506777B2 (en)
BE (1) BE846829A (en)
BG (1) BG25380A3 (en)
CA (1) CA1080145A (en)
CH (1) CH629531A5 (en)
CS (1) CS212776B2 (en)
DD (1) DD127442A5 (en)
DE (1) DE2643485A1 (en)
DK (1) DK143608C (en)
ES (1) ES452021A1 (en)
FR (1) FR2326200A1 (en)
GB (2) GB1499710A (en)
GR (1) GR61730B (en)
HU (1) HU173445B (en)
IE (1) IE43663B1 (en)
IL (1) IL50429A (en)
NL (1) NL7610808A (en)
NZ (1) NZ182123A (en)
PL (1) PL103996B1 (en)
PT (1) PT65617B (en)
RO (1) RO69985A (en)
SE (1) SE7610943L (en)
SU (1) SU620215A3 (en)
YU (1) YU236076A (en)
ZA (1) ZA765320B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5452797A (en) * 1977-10-04 1979-04-25 Meiji Seika Kaisha Ltd Novel antibiotic substance bn-200, and its preparation
CA1170598A (en) * 1979-12-13 1984-07-10 Bernard J. Abbott Process for the preparation of cyclic peptide nuclei
GB2180464A (en) * 1985-09-18 1987-04-01 British Gas Corp Gas-solid phase reactions and apparatus therefor
FI76004B (en) * 1986-03-24 1988-05-31 Seppo Kalervo Ruottu CIRKULATIONSMASSAREAKTOR.

Also Published As

Publication number Publication date
IE43663B1 (en) 1981-04-22
AR209993A1 (en) 1977-06-15
SU620215A3 (en) 1978-08-15
DD127442A5 (en) 1977-09-21
FR2326200B1 (en) 1980-03-07
IE43663L (en) 1977-04-02
GR61730B (en) 1978-12-30
CS212776B2 (en) 1982-03-26
DK440276A (en) 1977-04-03
NZ182123A (en) 1978-06-02
AU1808076A (en) 1978-04-06
GB1565821A (en) 1980-04-23
BE846829A (en) 1977-04-01
ATA730976A (en) 1978-03-15
YU236076A (en) 1983-04-30
JPS5242801A (en) 1977-04-04
DK143608B (en) 1981-09-14
BG25380A3 (en) 1978-09-15
PT65617A (en) 1976-10-01
ZA765320B (en) 1978-04-26
ES452021A1 (en) 1977-12-01
DE2643485A1 (en) 1977-04-14
PT65617B (en) 1978-04-05
GB1499710A (en) 1978-02-01
NL7610808A (en) 1977-04-05
CA1080145A (en) 1980-06-24
DK143608C (en) 1982-02-15
FR2326200A1 (en) 1977-04-29
AT346479B (en) 1978-11-10
RO69985A (en) 1981-05-15
PL103996B1 (en) 1979-07-31
HU173445B (en) 1979-05-28
IL50429A (en) 1979-11-30
IL50429A0 (en) 1976-11-30
CH629531A5 (en) 1982-04-30
AU506777B2 (en) 1980-01-24

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