CS209897B2 - Method of making the new substituted 2-piperazinyl-4h-s-triazolo /3,4c/ thieno /2,3c/-1,4-diazepines - Google Patents

Method of making the new substituted 2-piperazinyl-4h-s-triazolo /3,4c/ thieno /2,3c/-1,4-diazepines Download PDF

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Publication number
CS209897B2
CS209897B2 CS784821A CS482178A CS209897B2 CS 209897 B2 CS209897 B2 CS 209897B2 CS 784821 A CS784821 A CS 784821A CS 482178 A CS482178 A CS 482178A CS 209897 B2 CS209897 B2 CS 209897B2
Authority
CS
Czechoslovakia
Prior art keywords
triazolo
formula
alkyl
thieno
chlorophenyl
Prior art date
Application number
CS784821A
Other languages
Czech (cs)
English (en)
Inventor
Karl-Heinz Weber
Adolf Langbein
Claus Schneider
Erich Lehr
Karin Boeke
Franz J Kuhn
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19772732943 external-priority patent/DE2732943A1/de
Priority claimed from DE19772732921 external-priority patent/DE2732921A1/de
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Priority to CS801311A priority Critical patent/CS209898B2/cs
Priority to CS801312A priority patent/CS209899B2/cs
Publication of CS209897B2 publication Critical patent/CS209897B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS784821A 1977-07-21 1978-07-19 Method of making the new substituted 2-piperazinyl-4h-s-triazolo /3,4c/ thieno /2,3c/-1,4-diazepines CS209897B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CS801311A CS209898B2 (cs) 1977-07-21 1980-02-26 Způsob výroby nových substituovaných l-piperazinyl-4H-s-triazolo- [ 3,4c ] thieno [ 2,3e ] -1,4-diazepinů
CS801312A CS209899B2 (en) 1977-07-21 1980-02-26 Method of making the new substituted 1-piperazinyl-4h-s-triazolo /3,4c/ thieno/2,3e/ -1,4-diazepines

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19772732943 DE2732943A1 (de) 1977-07-21 1977-07-21 Neue substituierte 1-piperazinyl- 4h-s-triazolo eckige klammer auf 3,4c eckige klammer zu thieno eckige klammer auf 2,3e eckige klammer zu 1,4-diazepine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
DE19772732921 DE2732921A1 (de) 1977-07-21 1977-07-21 Neue substituierte 1-acyl-piperidino- bzw. -piperazino-4h-s-triazolo eckige klammer auf 3,4c eckige klammer zu thieno eckige klammer auf 2,3e eckige klammer zu 1,4- diazepine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen

Publications (1)

Publication Number Publication Date
CS209897B2 true CS209897B2 (en) 1981-12-31

Family

ID=25772369

Family Applications (1)

Application Number Title Priority Date Filing Date
CS784821A CS209897B2 (en) 1977-07-21 1978-07-19 Method of making the new substituted 2-piperazinyl-4h-s-triazolo /3,4c/ thieno /2,3c/-1,4-diazepines

Country Status (30)

Country Link
US (1) US4180573A (sv)
EP (1) EP0000479B1 (sv)
JP (1) JPS5422395A (sv)
AT (1) AT363949B (sv)
AU (1) AU515885B2 (sv)
CA (1) CA1087182A (sv)
CH (1) CH642374A5 (sv)
CS (1) CS209897B2 (sv)
DD (1) DD137934A5 (sv)
DE (1) DE2860404D1 (sv)
DK (1) DK150306C (sv)
ES (2) ES471886A1 (sv)
FI (1) FI63033C (sv)
FR (1) FR2398070A1 (sv)
GB (1) GB2001972B (sv)
GR (1) GR65022B (sv)
HU (1) HU176485B (sv)
IE (1) IE47336B1 (sv)
IL (1) IL55169A (sv)
IT (1) IT1107490B (sv)
LU (1) LU80002A1 (sv)
NL (1) NL7807762A (sv)
NO (1) NO149889C (sv)
NZ (1) NZ187915A (sv)
PH (1) PH14236A (sv)
PL (1) PL115061B1 (sv)
PT (1) PT68330A (sv)
RO (1) RO75609A (sv)
SE (1) SE439920B (sv)
SU (2) SU725564A3 (sv)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2830782A1 (de) * 1978-07-13 1980-01-24 Boehringer Sohn Ingelheim Neue substituierte 4h-s-triazolo eckige klammer auf 3,4c eckige klammer zu thieno eckige klammer auf 2,3e eckige klammer zu 1,4-diazepine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
ES2037013T3 (es) * 1986-01-21 1993-06-16 Boehringer Ingelheim Kg Procedimiento para preparar tieno-1,4-diazepinas.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH12303A (en) * 1973-02-08 1979-01-16 Hoffmann La Roche Thienotriazolodiazepine derivatives
AT338799B (de) * 1974-03-02 1977-09-12 Boehringer Sohn Ingelheim Verfahren zur herstellung neuer substituierter 6-aryl-4h-s-triazolo-(3,4c)-thieno-(2,3e)-1,4-diazepine und ihrer salze
US3894025A (en) * 1974-03-21 1975-07-08 Upjohn Co 1-Piperazino-6-phenyl-4H-s-triazolo{8 4,3-a{9 {8 1,4{9 -benzodiazepine compounds
JPS5747916B2 (sv) * 1974-05-13 1982-10-13
DE2503235A1 (de) * 1975-01-27 1976-07-29 Boehringer Sohn Ingelheim Neues verfahren zur herstellung von 8-brom-thieno-triazolo-1,4-diazepinen
DE2533924C3 (de) * 1975-07-30 1979-05-03 C.H. Boehringer Sohn, 6507 Ingelheim Verfahren zur Herstellung von 6- Aryl-4H-striazolo [3,4-c] thieno [2,3-e] 1,4-diazepinen
DE2531678C3 (de) * 1975-07-16 1979-06-28 C.H. Boehringer Sohn, 6507 Ingelheim Thieno [2,3e] triazole [3,4c] 5,6-dihydro-l,4diazepine und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
SE439920B (sv) 1985-07-08
NO782499L (no) 1979-01-23
CA1087182A (en) 1980-10-07
FR2398070A1 (fr) 1979-02-16
GB2001972B (en) 1982-01-06
DK325178A (da) 1979-01-22
IT1107490B (it) 1985-11-25
GB2001972A (en) 1979-02-14
ES471886A1 (es) 1979-02-01
ES472812A1 (es) 1979-02-16
IE47336B1 (en) 1984-02-22
LU80002A1 (de) 1979-09-06
DK150306C (da) 1987-11-09
JPS6254114B2 (sv) 1987-11-13
AU515885B2 (en) 1981-05-07
NZ187915A (en) 1980-10-08
RO75609A (ro) 1981-01-30
SU725564A1 (ru) 1980-03-30
AU3820978A (en) 1980-01-24
HU176485B (en) 1981-03-28
SU725564A3 (en) 1980-03-30
SE7808019L (sv) 1979-01-22
FR2398070B1 (sv) 1982-05-21
JPS5422395A (en) 1979-02-20
DD137934A5 (de) 1979-10-03
EP0000479B1 (de) 1981-01-07
SU793402A3 (ru) 1980-12-30
PT68330A (de) 1978-08-01
FI782025A (fi) 1979-01-22
FI63033B (fi) 1982-12-31
GR65022B (en) 1980-06-16
IE781456L (en) 1979-01-21
FI63033C (fi) 1983-04-11
EP0000479A1 (de) 1979-02-07
IT7850381A0 (it) 1978-07-19
IL55169A0 (en) 1978-09-29
NL7807762A (nl) 1979-01-23
PH14236A (en) 1981-04-09
CH642374A5 (de) 1984-04-13
PL208542A1 (pl) 1979-06-04
NO149889B (no) 1984-04-02
PL115061B1 (en) 1981-03-31
IL55169A (en) 1982-04-30
NO149889C (no) 1984-07-11
US4180573A (en) 1979-12-25
AT363949B (de) 1981-09-10
DK150306B (da) 1987-02-02
ATA498978A (de) 1981-02-15
DE2860404D1 (en) 1981-02-26

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