CS205009B2 - Process for preparing 7-hydroxyestradioles - Google Patents

Process for preparing 7-hydroxyestradioles Download PDF

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Publication number
CS205009B2
CS205009B2 CS756759A CS675975A CS205009B2 CS 205009 B2 CS205009 B2 CS 205009B2 CS 756759 A CS756759 A CS 756759A CS 675975 A CS675975 A CS 675975A CS 205009 B2 CS205009 B2 CS 205009B2
Authority
CS
Czechoslovakia
Prior art keywords
ethynyl
group
carbon atoms
acid
formula
Prior art date
Application number
CS756759A
Other languages
Czech (cs)
English (en)
Inventor
Petzoldt
Hans-Joerg Vidic
Klaus Prezewowsky
Yukishige Nishino
Rudolf Wiechert
Henry Laurent
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2449327A external-priority patent/DE2449327C2/de
Priority claimed from DE19752535997 external-priority patent/DE2535997A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of CS205009B2 publication Critical patent/CS205009B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0059Estrane derivatives substituted in position 17 by a keto group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0081Substituted in position 17 alfa and 17 beta
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0081Substituted in position 17 alfa and 17 beta
    • C07J1/0088Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0096Alkynyl derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi
    • Y10S435/912Absidia
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi
    • Y10S435/913Aspergillus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi
    • Y10S435/939Rhizopus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CS756759A 1974-10-14 1975-10-06 Process for preparing 7-hydroxyestradioles CS205009B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2449327A DE2449327C2 (de) 1974-10-14 1974-10-14 7 α-Hydroxy-östradiole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE19752535997 DE2535997A1 (de) 1975-08-08 1975-08-08 7-hydroxy-oestradiole

Publications (1)

Publication Number Publication Date
CS205009B2 true CS205009B2 (en) 1981-04-30

Family

ID=25767825

Family Applications (2)

Application Number Title Priority Date Filing Date
CS756759A CS205009B2 (en) 1974-10-14 1975-10-06 Process for preparing 7-hydroxyestradioles
CS756759A CS205010B2 (en) 1974-10-14 1975-10-06 Method of producing 7-hydroxy estradiols

Family Applications After (1)

Application Number Title Priority Date Filing Date
CS756759A CS205010B2 (en) 1974-10-14 1975-10-06 Method of producing 7-hydroxy estradiols

Country Status (23)

Country Link
US (1) US4011314A (US20110232667A1-20110929-C00004.png)
JP (1) JPS5165747A (US20110232667A1-20110929-C00004.png)
AT (1) AT348695B (US20110232667A1-20110929-C00004.png)
CA (1) CA1054143A (US20110232667A1-20110929-C00004.png)
CH (2) CH619240A5 (US20110232667A1-20110929-C00004.png)
CS (2) CS205009B2 (US20110232667A1-20110929-C00004.png)
DD (1) DD125588A5 (US20110232667A1-20110929-C00004.png)
DK (1) DK135378C (US20110232667A1-20110929-C00004.png)
ES (1) ES441784A1 (US20110232667A1-20110929-C00004.png)
FI (1) FI54603C (US20110232667A1-20110929-C00004.png)
FR (1) FR2287908A1 (US20110232667A1-20110929-C00004.png)
GB (1) GB1528796A (US20110232667A1-20110929-C00004.png)
HU (1) HU176715B (US20110232667A1-20110929-C00004.png)
IE (1) IE42167B1 (US20110232667A1-20110929-C00004.png)
IL (1) IL48276A (US20110232667A1-20110929-C00004.png)
NL (1) NL7512041A (US20110232667A1-20110929-C00004.png)
NO (1) NO140824C (US20110232667A1-20110929-C00004.png)
NZ (1) NZ178886A (US20110232667A1-20110929-C00004.png)
PH (1) PH13802A (US20110232667A1-20110929-C00004.png)
PL (2) PL103989B1 (US20110232667A1-20110929-C00004.png)
SE (1) SE405254B (US20110232667A1-20110929-C00004.png)
SU (2) SU676170A3 (US20110232667A1-20110929-C00004.png)
YU (2) YU243975A (US20110232667A1-20110929-C00004.png)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8327256D0 (en) * 1983-10-12 1983-11-16 Ici Plc Steroid derivatives
DE3741800A1 (de) * 1987-12-07 1989-06-15 Schering Ag 17-halogenmethylen-estratriene
US5861431A (en) * 1995-06-07 1999-01-19 Iotek, Inc. Incontinence treatment
JP2000511404A (ja) 1996-04-09 2000-09-05 ビー・テイー・ジー・インターナシヨナル・リミテツド 神経精神、免疫又は内分泌障害を治療するための7α置換ステロイドの使用
EP2322182A1 (en) 1999-09-30 2011-05-18 Harbor BioSciences, Inc. Androstenol derivatives as androgen receptor modulator
GB0003524D0 (en) * 2000-02-15 2000-04-05 Btg Int Ltd Cytoprotective steroids (II)
GB2363983A (en) * 2000-06-29 2002-01-16 Hunter Fleming Ltd Protection against neuronal damage using 7-hydroxyepiandrosterone
DK1624878T3 (da) * 2003-05-22 2007-01-08 Pantarhei Bioscience Bv Anvendelse af præparater som omfatter en östrogen komponent til behandling og forebyggelse af muskel-skelet-smerte
GB0403889D0 (en) * 2004-02-21 2004-03-24 Univ Edinburgh Uses of er-beta modulators
US7910755B2 (en) 2004-09-29 2011-03-22 Harbor Biosciences, Inc. Stem cell expansion and uses

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3115444A (en) * 1962-01-22 1963-12-24 Olin Mathieson Process for microbial hydroxylation of steroids containing aromatic alpha-rings

Also Published As

Publication number Publication date
DK135378C (da) 1977-10-03
IE42167B1 (en) 1980-06-18
PL103989B1 (pl) 1979-07-31
NL7512041A (nl) 1976-04-20
DK439975A (da) 1976-04-15
HU176715B (en) 1981-04-28
GB1528796A (en) 1978-10-18
YU243975A (en) 1982-06-30
IE42167L (en) 1976-04-14
US4011314A (en) 1977-03-08
NZ178886A (en) 1978-04-28
PH13802A (en) 1980-10-01
IL48276A (en) 1979-03-12
IL48276A0 (en) 1975-12-31
NO140824B (no) 1979-08-13
FR2287908B1 (US20110232667A1-20110929-C00004.png) 1980-04-30
JPS5165747A (en) 1976-06-07
ES441784A1 (es) 1977-04-01
ATA775475A (de) 1978-07-15
NO140824C (no) 1979-11-21
DD125588A5 (US20110232667A1-20110929-C00004.png) 1977-05-04
NO753455L (US20110232667A1-20110929-C00004.png) 1976-04-20
DK135378B (da) 1977-04-18
SE7511438L (sv) 1976-04-15
SE405254B (sv) 1978-11-27
FR2287908A1 (fr) 1976-05-14
CA1054143A (en) 1979-05-08
CS205010B2 (en) 1981-04-30
PL101461B1 (pl) 1978-12-30
CH619240A5 (US20110232667A1-20110929-C00004.png) 1980-09-15
YU294281A (en) 1982-06-30
AU8571075A (en) 1977-04-21
SU677666A1 (ru) 1981-11-30
AT348695B (de) 1979-02-26
FI752836A (US20110232667A1-20110929-C00004.png) 1976-04-15
FI54603B (fi) 1978-09-29
SU676170A3 (ru) 1979-07-25
SU677666A3 (en) 1981-11-30
FI54603C (fi) 1979-01-10
CH619268A5 (US20110232667A1-20110929-C00004.png) 1980-09-15

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