CS203176B2 - Agents for the suppressin of coccidiose - Google Patents
Agents for the suppressin of coccidiose Download PDFInfo
- Publication number
- CS203176B2 CS203176B2 CS776980A CS698077A CS203176B2 CS 203176 B2 CS203176 B2 CS 203176B2 CS 776980 A CS776980 A CS 776980A CS 698077 A CS698077 A CS 698077A CS 203176 B2 CS203176 B2 CS 203176B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- alkyl radical
- oocysts
- methyl
- formula
- contain
- Prior art date
Links
- 208000003495 Coccidiosis Diseases 0.000 title claims description 8
- 102100036727 Deformed epidermal autoregulatory factor 1 homolog Human genes 0.000 title 1
- 101710172577 Deformed epidermal autoregulatory factor 1 homolog Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract description 15
- 239000000203 mixture Substances 0.000 claims abstract description 13
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract description 9
- 239000001257 hydrogen Substances 0.000 claims abstract description 9
- 125000004432 carbon atom Chemical group C* 0.000 claims abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims abstract 3
- 210000003250 oocyst Anatomy 0.000 claims description 21
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 20
- 239000013543 active substance Substances 0.000 claims description 10
- 206010023076 Isosporiasis Diseases 0.000 claims description 7
- 125000000217 alkyl group Chemical group 0.000 claims description 6
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 4
- -1 n-nonyl Chemical group 0.000 claims description 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 3
- 150000002431 hydrogen Chemical class 0.000 claims description 3
- 239000004480 active ingredient Substances 0.000 claims 1
- JRBPAEWTRLWTQC-UHFFFAOYSA-N dodecylamine Chemical compound CCCCCCCCCCCCN JRBPAEWTRLWTQC-UHFFFAOYSA-N 0.000 claims 1
- 208000015336 Helminthic disease Diseases 0.000 abstract 1
- 235000013601 eggs Nutrition 0.000 description 15
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 14
- 241000244203 Caenorhabditis elegans Species 0.000 description 8
- 239000008399 tap water Substances 0.000 description 7
- 235000020679 tap water Nutrition 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- 241001465754 Metazoa Species 0.000 description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 241000244188 Ascaris suum Species 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 239000008187 granular material Substances 0.000 description 5
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 description 4
- 241000287828 Gallus gallus Species 0.000 description 4
- WTDHULULXKLSOZ-UHFFFAOYSA-N Hydroxylamine hydrochloride Chemical compound Cl.ON WTDHULULXKLSOZ-UHFFFAOYSA-N 0.000 description 4
- 235000013330 chicken meat Nutrition 0.000 description 4
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- WCLHZVGJULAEJH-UHFFFAOYSA-N tridecan-2-amine Chemical compound CCCCCCCCCCCC(C)N WCLHZVGJULAEJH-UHFFFAOYSA-N 0.000 description 4
- 241000224483 Coccidia Species 0.000 description 3
- 241000223932 Eimeria tenella Species 0.000 description 3
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 3
- 230000001165 anti-coccidial effect Effects 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 238000009835 boiling Methods 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 239000012259 ether extract Substances 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 244000000013 helminth Species 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 244000144972 livestock Species 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 239000011541 reaction mixture Substances 0.000 description 3
- 229910052938 sodium sulfate Inorganic materials 0.000 description 3
- 235000011152 sodium sulphate Nutrition 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 description 2
- 208000006968 Helminthiasis Diseases 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 description 2
- 241000244030 Toxocara canis Species 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 238000011260 co-administration Methods 0.000 description 2
- 235000019253 formic acid Nutrition 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- BTGDLFQKTQENBZ-UHFFFAOYSA-N n-tridecan-2-ylformamide Chemical compound CCCCCCCCCCCC(C)NC=O BTGDLFQKTQENBZ-UHFFFAOYSA-N 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 230000003071 parasitic effect Effects 0.000 description 2
- 208000014837 parasitic helminthiasis infectious disease Diseases 0.000 description 2
- KMUONIBRACKNSN-UHFFFAOYSA-N potassium dichromate Chemical compound [K+].[K+].[O-][Cr](=O)(=O)O[Cr]([O-])(=O)=O KMUONIBRACKNSN-UHFFFAOYSA-N 0.000 description 2
- 244000144977 poultry Species 0.000 description 2
- 235000013594 poultry meat Nutrition 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 230000028070 sporulation Effects 0.000 description 2
- XSXGPOWIKPOMRY-UHFFFAOYSA-N tricosa-1,22-dien-12-one Chemical compound C=CCCCCCCCCCC(=O)CCCCCCCCCC=C XSXGPOWIKPOMRY-UHFFFAOYSA-N 0.000 description 2
- 241000204727 Ascaridia Species 0.000 description 1
- 241000252983 Caecum Species 0.000 description 1
- 241000223924 Eimeria Species 0.000 description 1
- 241000223931 Eimeria acervulina Species 0.000 description 1
- 241000499566 Eimeria brunetti Species 0.000 description 1
- 241000223934 Eimeria maxima Species 0.000 description 1
- 241000499563 Eimeria necatrix Species 0.000 description 1
- 101100476308 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) hel-2 gene Proteins 0.000 description 1
- 206010047897 Weight gain poor Diseases 0.000 description 1
- 230000001464 adherent effect Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 150000001299 aldehydes Chemical class 0.000 description 1
- 239000012670 alkaline solution Substances 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 238000010531 catalytic reduction reaction Methods 0.000 description 1
- 210000004534 cecum Anatomy 0.000 description 1
- 210000001072 colon Anatomy 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000004491 dispersible concentrate Substances 0.000 description 1
- 239000002270 dispersing agent Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000010410 dusting Methods 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 230000002550 fecal effect Effects 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 210000002216 heart Anatomy 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 230000003903 intestinal lesions Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- RISFWNKJKLLNOV-UHFFFAOYSA-N n-tridecan-2-ylidenehydroxylamine Chemical compound CCCCCCCCCCCC(C)=NO RISFWNKJKLLNOV-UHFFFAOYSA-N 0.000 description 1
- 238000006053 organic reaction Methods 0.000 description 1
- 230000003151 ovacidal effect Effects 0.000 description 1
- 210000003101 oviduct Anatomy 0.000 description 1
- 150000002923 oximes Chemical class 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000009374 poultry farming Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 238000006722 reduction reaction Methods 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1354176 | 1976-10-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS203176B2 true CS203176B2 (en) | 1981-02-27 |
Family
ID=4393309
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS776980A CS203176B2 (en) | 1976-10-27 | 1977-10-26 | Agents for the suppressin of coccidiose |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4263324A (de) |
| JP (1) | JPS5356324A (de) |
| AT (1) | AT356963B (de) |
| AU (1) | AU3007277A (de) |
| BE (1) | BE860110A (de) |
| CS (1) | CS203176B2 (de) |
| DE (1) | DE2747580A1 (de) |
| DK (1) | DK476077A (de) |
| FR (1) | FR2368950A1 (de) |
| GB (1) | GB1593194A (de) |
| IL (1) | IL53217A0 (de) |
| NL (1) | NL7711756A (de) |
| NZ (1) | NZ185526A (de) |
| SE (1) | SE7712046L (de) |
| ZA (1) | ZA776372B (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1985002173A1 (en) * | 1983-11-10 | 1985-05-23 | Monsanto Company | New route to long chain amines |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1528M (fr) * | 1961-08-04 | 1962-10-15 | Pfizer & Co C | Agents thérapeutiques anthelminthiques. |
| US3226293A (en) * | 1961-12-21 | 1965-12-28 | Pfizer & Co C | Octadecyl amine anthelmintic compositions and therapy |
| BE711541A (de) * | 1967-03-06 | 1968-07-15 | ||
| DE2809491A1 (de) * | 1977-03-09 | 1978-09-14 | Ciba Geigy Ag | Anticoccidielle und ovo-larvicide mittel |
-
1977
- 1977-10-24 GB GB44221/77A patent/GB1593194A/en not_active Expired
- 1977-10-24 DE DE19772747580 patent/DE2747580A1/de not_active Withdrawn
- 1977-10-25 IL IL53217A patent/IL53217A0/xx unknown
- 1977-10-25 AT AT761877A patent/AT356963B/de not_active IP Right Cessation
- 1977-10-26 NL NL7711756A patent/NL7711756A/xx not_active Application Discontinuation
- 1977-10-26 NZ NZ185526A patent/NZ185526A/xx unknown
- 1977-10-26 BE BE182057A patent/BE860110A/xx unknown
- 1977-10-26 SE SE7712046A patent/SE7712046L/xx unknown
- 1977-10-26 DK DK476077A patent/DK476077A/da unknown
- 1977-10-26 ZA ZA00776372A patent/ZA776372B/xx unknown
- 1977-10-26 AU AU30072/77A patent/AU3007277A/en active Pending
- 1977-10-26 FR FR7732205A patent/FR2368950A1/fr active Granted
- 1977-10-26 CS CS776980A patent/CS203176B2/cs unknown
- 1977-10-27 JP JP12915277A patent/JPS5356324A/ja active Pending
-
1979
- 1979-08-27 US US06/070,217 patent/US4263324A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DK476077A (da) | 1978-04-28 |
| NL7711756A (nl) | 1978-05-02 |
| AT356963B (de) | 1980-06-10 |
| BE860110A (fr) | 1978-04-26 |
| SE7712046L (sv) | 1978-04-28 |
| ZA776372B (en) | 1978-08-30 |
| ATA761877A (de) | 1979-10-15 |
| DE2747580A1 (de) | 1978-05-11 |
| JPS5356324A (en) | 1978-05-22 |
| US4263324A (en) | 1981-04-21 |
| IL53217A0 (en) | 1977-12-30 |
| FR2368950A1 (fr) | 1978-05-26 |
| FR2368950B1 (de) | 1979-03-02 |
| AU3007277A (en) | 1979-05-03 |
| NZ185526A (en) | 1980-10-08 |
| GB1593194A (en) | 1981-07-15 |
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