CS203037B2 - Method of producing n-cyan-n'-methyl-n''-/2-/ methyl-5-imidazolyl/methylthio/ethyl/guanidine - Google Patents

Method of producing n-cyan-n'-methyl-n''-/2-/ methyl-5-imidazolyl/methylthio/ethyl/guanidine Download PDF

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Publication number
CS203037B2
CS203037B2 CS792885A CS288579A CS203037B2 CS 203037 B2 CS203037 B2 CS 203037B2 CS 792885 A CS792885 A CS 792885A CS 288579 A CS288579 A CS 288579A CS 203037 B2 CS203037 B2 CS 203037B2
Authority
CS
Czechoslovakia
Prior art keywords
methyl
guanidine
ethyl
cyano
imidazolyl
Prior art date
Application number
CS792885A
Other languages
Czech (cs)
English (en)
Inventor
Branko Jenko
Igor Langof
Joza Habjan
Original Assignee
Lek Tovarna Farmacevtskih
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Tovarna Farmacevtskih filed Critical Lek Tovarna Farmacevtskih
Publication of CS203037B2 publication Critical patent/CS203037B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/28—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C07C323/44—X or Y being nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CS792885A 1978-04-26 1979-04-25 Method of producing n-cyan-n'-methyl-n''-/2-/ methyl-5-imidazolyl/methylthio/ethyl/guanidine CS203037B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YU998/78A YU40332B (en) 1978-04-26 1978-04-26 Process for preparing n-cyano-n'-methyl-n''-((2-((4-methyl-5-imidazolyl)-methylthio)ethyl)-guanidine

Publications (1)

Publication Number Publication Date
CS203037B2 true CS203037B2 (en) 1981-02-27

Family

ID=25552339

Family Applications (1)

Application Number Title Priority Date Filing Date
CS792885A CS203037B2 (en) 1978-04-26 1979-04-25 Method of producing n-cyan-n'-methyl-n''-/2-/ methyl-5-imidazolyl/methylthio/ethyl/guanidine

Country Status (19)

Country Link
US (1) US4200761A (de)
JP (1) JPS5440547B1 (de)
AR (1) AR219794A1 (de)
AT (1) AT363956B (de)
BE (1) BE875845A (de)
CA (2) CA1121363A (de)
CS (1) CS203037B2 (de)
DD (1) DD143256A5 (de)
DE (1) DE2916610C2 (de)
ES (1) ES479925A1 (de)
FR (1) FR2424261A1 (de)
GB (2) GB2041362B (de)
HU (1) HU180830B (de)
IT (1) IT1165198B (de)
PL (1) PL115342B1 (de)
PT (1) PT69542A (de)
RO (1) RO78325A (de)
SU (1) SU862822A3 (de)
YU (1) YU40332B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6056139B2 (ja) * 1980-11-26 1985-12-09 藤本製薬株式会社 シアノグアニジン誘導体の製造法
CN111848458B (zh) * 2020-08-05 2022-04-26 原平市同利化工有限责任公司 一种制备3-巯基丙酸的过程中提取双氰胺的工艺
CN115784940B (zh) * 2022-12-07 2023-12-05 内蒙古欣皓医药科技有限公司 一种双氰胺晶体的结晶方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
GB1397436A (en) * 1972-09-05 1975-06-11 Smith Kline French Lab Heterocyclic n-cyanoguinidines
US4025527A (en) * 1973-07-13 1977-05-24 Smith Kline & French Laboratories Limited Certain thiazoles and oxazoles
GB1533380A (en) * 1974-09-02 1978-11-22 Smith Kline French Lab Process for the preparation of heterocyclic substituted thioureas and h-cyanoguanidines
GB1531231A (en) * 1974-09-02 1978-11-08 Smith Kline French Lab Process for the production of cyanoguanidine derivatives
US4112234A (en) * 1977-08-22 1978-09-05 Bristol-Myers Company Imidazolylmethylthioethyl alkynyl guanidines
IL56265A (en) * 1977-12-28 1982-08-31 Om Lab Sa Process for preparing imidazolyl methylthio guanidine derivatives and a novel intermediate therefor
CH631971A5 (en) * 1977-12-30 1982-09-15 Crc Ricerca Chim Process for preparing imidazole derivatives

Also Published As

Publication number Publication date
FR2424261A1 (fr) 1979-11-23
ATA282779A (de) 1981-02-15
PL115342B1 (en) 1981-03-31
PL215185A1 (de) 1980-01-28
YU99878A (en) 1982-10-31
SU862822A3 (ru) 1981-09-07
US4200761A (en) 1980-04-29
CA1209153B (en) 1986-08-05
GB2019842A (en) 1979-11-07
HU180830B (en) 1983-04-29
YU40332B (en) 1985-12-31
DE2916610A1 (de) 1979-10-31
GB2019842B (en) 1982-10-13
AR219794A1 (es) 1980-09-15
PT69542A (en) 1979-05-01
JPS5440547B1 (de) 1979-12-04
FR2424261B1 (de) 1983-05-13
DD143256A5 (de) 1980-08-13
CA1121363A (en) 1982-04-06
RO78325A (ro) 1982-04-12
AT363956B (de) 1981-09-10
IT7967876A0 (it) 1979-04-24
ES479925A1 (es) 1979-12-01
DE2916610C2 (de) 1986-04-03
GB2041362B (en) 1982-08-18
GB2041362A (en) 1980-09-10
IT1165198B (it) 1987-04-22
BE875845A (fr) 1979-08-16

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