YU40332B - Process for preparing n-cyano-n'-methyl-n''-((2-((4-methyl-5-imidazolyl)-methylthio)ethyl)-guanidine - Google Patents

Process for preparing n-cyano-n'-methyl-n''-((2-((4-methyl-5-imidazolyl)-methylthio)ethyl)-guanidine

Info

Publication number
YU40332B
YU40332B YU998/78A YU99878A YU40332B YU 40332 B YU40332 B YU 40332B YU 998/78 A YU998/78 A YU 998/78A YU 99878 A YU99878 A YU 99878A YU 40332 B YU40332 B YU 40332B
Authority
YU
Yugoslavia
Prior art keywords
methyl
methylthio
guanidine
imidazolyl
cyano
Prior art date
Application number
YU998/78A
Other languages
English (en)
Other versions
YU99878A (en
Inventor
B Jenko
J Langof
J Habjan
Original Assignee
Lek Tovarna Farmacevtskih
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Tovarna Farmacevtskih filed Critical Lek Tovarna Farmacevtskih
Priority to YU998/78A priority Critical patent/YU40332B/xx
Priority to AT0282779A priority patent/AT363956B/de
Priority to US06/031,239 priority patent/US4200761A/en
Priority to GB7913760A priority patent/GB2019842B/en
Priority to GB8000974A priority patent/GB2041362B/en
Priority to CA000326202A priority patent/CA1121363A/en
Priority to PT69542A priority patent/PT69542A/pt
Priority to DE2916610A priority patent/DE2916610C2/de
Priority to IT67876/79A priority patent/IT1165198B/it
Priority to MX10123479U priority patent/MX6145E/es
Priority to AR276281A priority patent/AR219794A1/es
Priority to RO7997352A priority patent/RO78325A/ro
Priority to JP4983679A priority patent/JPS5440547B1/ja
Priority to ES479925A priority patent/ES479925A1/es
Priority to SU792760898A priority patent/SU862822A3/ru
Priority to BE0/194829A priority patent/BE875845A/xx
Priority to DD79212494A priority patent/DD143256A5/de
Priority to CS792885A priority patent/CS203037B2/cs
Priority to HU79LE840A priority patent/HU180830B/hu
Priority to FR7910594A priority patent/FR2424261A1/fr
Priority to PL1979215185A priority patent/PL115342B1/pl
Publication of YU99878A publication Critical patent/YU99878A/xx
Priority to CA000491471A priority patent/CA1209153B/en
Publication of YU40332B publication Critical patent/YU40332B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/28—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C07C323/44—X or Y being nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
YU998/78A 1978-04-26 1978-04-26 Process for preparing n-cyano-n'-methyl-n''-((2-((4-methyl-5-imidazolyl)-methylthio)ethyl)-guanidine YU40332B (en)

Priority Applications (22)

Application Number Priority Date Filing Date Title
YU998/78A YU40332B (en) 1978-04-26 1978-04-26 Process for preparing n-cyano-n'-methyl-n''-((2-((4-methyl-5-imidazolyl)-methylthio)ethyl)-guanidine
AT0282779A AT363956B (de) 1978-04-26 1979-04-17 Verfahren zur herstellung einer heterocyclischen verbindung
US06/031,239 US4200761A (en) 1978-04-26 1979-04-18 Process for preparing N-cyano-N'methyl-N"-{2-[(4-methyl-5-imidazolyl)-methylthio]-ethyl} guanidine
GB7913760A GB2019842B (en) 1978-04-26 1979-04-20 Process for preparing a heterocyclic compound
GB8000974A GB2041362B (en) 1978-04-26 1979-04-20 Heterocyclic compound
RO7997352A RO78325A (ro) 1978-04-26 1979-04-24 Procedeu pentru prepararea unor compusi heterociclici
PT69542A PT69542A (en) 1978-04-26 1979-04-24 A process for preparing a heterocyclic compound
DE2916610A DE2916610C2 (de) 1978-04-26 1979-04-24 Verfahren zur Herstellung von 1-Cyano-2-methyl-3-[2-[[(5-methyl-imidazol-4-yl)methyl]-thio]-äthyl]-guanidin
IT67876/79A IT1165198B (it) 1978-04-26 1979-04-24 Procedimento per la preparazione di un composto eterociclico ad attivita antistaminica
MX10123479U MX6145E (es) 1978-04-26 1979-04-24 Procedimiento para la preparacion de n-ciano n'-metil-n"-(2-((-metil-5-imidazolil)-metiltio/)guanidina
AR276281A AR219794A1 (es) 1978-04-26 1979-04-24 Procedimiento para preparar n-ciano -n'- metil -n''- -(2-((4- metil- 5-imidazolil)- metiltio)- etil) guanidina
CA000326202A CA1121363A (en) 1978-04-26 1979-04-24 Process to prepare n-cyano-n'-methyl-n''-(2-¬(4- methyl-5-imidazolyl)-methylthio|-ethyl) guanidine
JP4983679A JPS5440547B1 (xx) 1978-04-26 1979-04-24
SU792760898A SU862822A3 (ru) 1978-04-26 1979-04-25 Способ получени N-циано-N -метил-N 2 @ /4-метил-5-имидазолил/-метилтио @ -этил @ гуанидина
ES479925A ES479925A1 (es) 1978-04-26 1979-04-25 Procedimiento para preparar compuestos heterociclicos.
BE0/194829A BE875845A (fr) 1978-04-26 1979-04-25 Procede de preparation d'un compose heterocyclique
DD79212494A DD143256A5 (de) 1978-04-26 1979-04-25 Verfahren zur herstellung von n-cyano-n'-methyl-n"-(2-eckige klammer auf (4-methyl-5-imidazolyl)-methylthio eckige klammer zu -aethyl)-guanidin
CS792885A CS203037B2 (en) 1978-04-26 1979-04-25 Method of producing n-cyan-n'-methyl-n''-/2-/ methyl-5-imidazolyl/methylthio/ethyl/guanidine
HU79LE840A HU180830B (en) 1978-04-26 1979-04-26 Process for preparing isocyano-2-methyl-3-(2-/5-methyl-imidazol-4-yl/-methylthio/-ethyl)-guanidine
FR7910594A FR2424261A1 (fr) 1978-04-26 1979-04-26 Procede pour preparer un compose heterocyclique
PL1979215185A PL115342B1 (en) 1978-04-26 1979-04-26 Method of manufacture of n-cyano-n'-methyl-n''-(2/4-methyl-5-imidazolyl/-methylthio/-ethyl/-guanidine
CA000491471A CA1209153B (en) 1978-04-26 1985-09-24 Process to prepare n-cyano-n'-methyl-n"-(2-¬(4- methyl)-5-imidazolyl)-methylthio|-ethyl)-guanidine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YU998/78A YU40332B (en) 1978-04-26 1978-04-26 Process for preparing n-cyano-n'-methyl-n''-((2-((4-methyl-5-imidazolyl)-methylthio)ethyl)-guanidine

Publications (2)

Publication Number Publication Date
YU99878A YU99878A (en) 1982-10-31
YU40332B true YU40332B (en) 1985-12-31

Family

ID=25552339

Family Applications (1)

Application Number Title Priority Date Filing Date
YU998/78A YU40332B (en) 1978-04-26 1978-04-26 Process for preparing n-cyano-n'-methyl-n''-((2-((4-methyl-5-imidazolyl)-methylthio)ethyl)-guanidine

Country Status (19)

Country Link
US (1) US4200761A (xx)
JP (1) JPS5440547B1 (xx)
AR (1) AR219794A1 (xx)
AT (1) AT363956B (xx)
BE (1) BE875845A (xx)
CA (2) CA1121363A (xx)
CS (1) CS203037B2 (xx)
DD (1) DD143256A5 (xx)
DE (1) DE2916610C2 (xx)
ES (1) ES479925A1 (xx)
FR (1) FR2424261A1 (xx)
GB (2) GB2041362B (xx)
HU (1) HU180830B (xx)
IT (1) IT1165198B (xx)
PL (1) PL115342B1 (xx)
PT (1) PT69542A (xx)
RO (1) RO78325A (xx)
SU (1) SU862822A3 (xx)
YU (1) YU40332B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6056139B2 (ja) * 1980-11-26 1985-12-09 藤本製薬株式会社 シアノグアニジン誘導体の製造法
CN111848458B (zh) * 2020-08-05 2022-04-26 原平市同利化工有限责任公司 一种制备3-巯基丙酸的过程中提取双氰胺的工艺
CN115784940B (zh) * 2022-12-07 2023-12-05 内蒙古欣皓医药科技有限公司 一种双氰胺晶体的结晶方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
GB1397436A (en) * 1972-09-05 1975-06-11 Smith Kline French Lab Heterocyclic n-cyanoguinidines
US4025527A (en) * 1973-07-13 1977-05-24 Smith Kline & French Laboratories Limited Certain thiazoles and oxazoles
GB1533380A (en) * 1974-09-02 1978-11-22 Smith Kline French Lab Process for the preparation of heterocyclic substituted thioureas and h-cyanoguanidines
GB1531231A (en) * 1974-09-02 1978-11-08 Smith Kline French Lab Process for the production of cyanoguanidine derivatives
US4112234A (en) * 1977-08-22 1978-09-05 Bristol-Myers Company Imidazolylmethylthioethyl alkynyl guanidines
IL56265A (en) * 1977-12-28 1982-08-31 Om Lab Sa Process for preparing imidazolyl methylthio guanidine derivatives and a novel intermediate therefor
CH631971A5 (en) * 1977-12-30 1982-09-15 Crc Ricerca Chim Process for preparing imidazole derivatives

Also Published As

Publication number Publication date
FR2424261A1 (fr) 1979-11-23
ATA282779A (de) 1981-02-15
PL115342B1 (en) 1981-03-31
CS203037B2 (en) 1981-02-27
PL215185A1 (xx) 1980-01-28
YU99878A (en) 1982-10-31
SU862822A3 (ru) 1981-09-07
US4200761A (en) 1980-04-29
CA1209153B (en) 1986-08-05
GB2019842A (en) 1979-11-07
HU180830B (en) 1983-04-29
DE2916610A1 (de) 1979-10-31
GB2019842B (en) 1982-10-13
AR219794A1 (es) 1980-09-15
PT69542A (en) 1979-05-01
JPS5440547B1 (xx) 1979-12-04
FR2424261B1 (xx) 1983-05-13
DD143256A5 (de) 1980-08-13
CA1121363A (en) 1982-04-06
RO78325A (ro) 1982-04-12
AT363956B (de) 1981-09-10
IT7967876A0 (it) 1979-04-24
ES479925A1 (es) 1979-12-01
DE2916610C2 (de) 1986-04-03
GB2041362B (en) 1982-08-18
GB2041362A (en) 1980-09-10
IT1165198B (it) 1987-04-22
BE875845A (fr) 1979-08-16

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