CS202570B2 - Process for preparing aminoglycsidic antibiotics - Google Patents

Process for preparing aminoglycsidic antibiotics Download PDF

Info

Publication number
CS202570B2
CS202570B2 CS772453A CS245377A CS202570B2 CS 202570 B2 CS202570 B2 CS 202570B2 CS 772453 A CS772453 A CS 772453A CS 245377 A CS245377 A CS 245377A CS 202570 B2 CS202570 B2 CS 202570B2
Authority
CS
Czechoslovakia
Prior art keywords
group
formula
product
amino
benzyl
Prior art date
Application number
CS772453A
Other languages
Czech (cs)
English (en)
Inventor
William A Million
Rhona M Plews
Kenneth Richardson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to CS78731A priority Critical patent/CS202571B2/cs
Publication of CS202570B2 publication Critical patent/CS202570B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CS772453A 1976-04-14 1977-04-14 Process for preparing aminoglycsidic antibiotics CS202570B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CS78731A CS202571B2 (cs) 1976-04-14 1978-02-03 Způsob výroby selektivně chráněného derivátu kanamycinu A nebo kanamycinu B

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB15421/76A GB1530201A (en) 1976-04-14 1976-04-14 Process for the preparation of aminoglycoside antibiotics and intermediates therefor

Publications (1)

Publication Number Publication Date
CS202570B2 true CS202570B2 (en) 1981-01-30

Family

ID=10058845

Family Applications (1)

Application Number Title Priority Date Filing Date
CS772453A CS202570B2 (en) 1976-04-14 1977-04-14 Process for preparing aminoglycsidic antibiotics

Country Status (28)

Country Link
JP (2) JPS52139044A (fr)
AR (1) AR219074A1 (fr)
AT (1) AT356267B (fr)
AU (1) AU497416B2 (fr)
BE (1) BE853564A (fr)
BG (2) BG27759A3 (fr)
CA (1) CA1083568A (fr)
CH (1) CH622528A5 (fr)
CS (1) CS202570B2 (fr)
DD (2) DD130661A5 (fr)
DE (1) DE2716533C3 (fr)
DK (1) DK164277A (fr)
EG (1) EG12909A (fr)
ES (1) ES457793A1 (fr)
FI (1) FI771144A (fr)
FR (1) FR2348223A1 (fr)
GB (1) GB1530201A (fr)
GR (1) GR68936B (fr)
IE (1) IE45030B1 (fr)
IL (1) IL51775A (fr)
LU (1) LU77108A1 (fr)
NL (1) NL7703567A (fr)
NZ (1) NZ183733A (fr)
PH (1) PH14029A (fr)
PL (2) PL112867B1 (fr)
PT (1) PT66422B (fr)
RO (2) RO79969A (fr)
ZA (1) ZA771944B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2924659A1 (de) * 1979-06-19 1981-01-22 Bayer Ag Pseudotrisaccharide, ihre herstellung und verwendung als arzneimittel
JPH0414628Y2 (fr) * 1984-12-13 1992-04-02
JPS61191642U (fr) * 1985-05-20 1986-11-28
IT1225484B (it) * 1987-11-27 1990-11-14 Pierrel Spa Procedimento di sintesi dell'amikacina
CN101481397B (zh) * 2009-01-23 2012-10-31 北京大学 一种新的卡那霉素a衍生物及其制备方法和用途
AU2011326871B2 (en) 2010-11-08 2015-02-12 Albireo Ab IBAT inhibitors for the treatment of liver diseases
WO2015199146A1 (fr) 2014-06-25 2015-12-30 味の素株式会社 Préparation pharmaceutique solide, et procédé de stabilisation de celle-ci
WO2015199147A1 (fr) 2014-06-25 2015-12-30 味の素株式会社 Préparation pharmaceutique solide, et procédé d'inhibition ou d'atténuation de coloration de celle-ci
EP3012252A1 (fr) 2014-10-24 2016-04-27 Ferring BV Formes crystallines d'Elobixibat
US10441604B2 (en) 2016-02-09 2019-10-15 Albireo Ab Cholestyramine pellets and methods for preparation thereof
US10786529B2 (en) 2016-02-09 2020-09-29 Albireo Ab Oral cholestyramine formulation and use thereof
US10441605B2 (en) 2016-02-09 2019-10-15 Albireo Ab Oral cholestyramine formulation and use thereof
US10722457B2 (en) 2018-08-09 2020-07-28 Albireo Ab Oral cholestyramine formulation and use thereof
US11007142B2 (en) 2018-08-09 2021-05-18 Albireo Ab Oral cholestyramine formulation and use thereof

Also Published As

Publication number Publication date
PT66422A (en) 1977-05-01
DD135496A5 (de) 1979-05-09
DK164277A (da) 1977-10-15
PT66422B (en) 1978-09-18
BG28072A4 (en) 1980-02-25
JPS535141A (en) 1978-01-18
DE2716533B2 (de) 1981-04-30
FR2348223A1 (fr) 1977-11-10
DE2716533C3 (de) 1982-05-13
IL51775A0 (en) 1977-05-31
AU2372177A (en) 1978-10-05
RO74431A (fr) 1981-08-30
CH622528A5 (en) 1981-04-15
LU77108A1 (fr) 1979-01-18
DD130661A5 (de) 1978-04-19
NL7703567A (nl) 1977-10-18
AT356267B (de) 1980-04-25
IE45030B1 (en) 1982-06-02
GB1530201A (en) 1978-10-25
IE45030L (en) 1977-10-14
NZ183733A (en) 1979-12-11
CA1083568A (fr) 1980-08-12
JPS5549587B2 (fr) 1980-12-12
FI771144A (fr) 1977-10-15
BG27759A3 (en) 1979-12-12
AU497416B2 (en) 1978-12-14
ES457793A1 (es) 1978-08-01
JPS5421326B2 (fr) 1979-07-30
PL197372A1 (pl) 1979-06-18
IL51775A (en) 1980-07-31
BE853564A (fr) 1977-10-13
AR219074A1 (es) 1980-07-31
RO79969B (ro) 1983-01-30
RO79969A (fr) 1983-02-01
EG12909A (en) 1979-12-31
ATA261477A (de) 1979-09-15
JPS52139044A (en) 1977-11-19
DE2716533A1 (de) 1977-11-03
PL112867B1 (en) 1980-11-29
GR68936B (fr) 1982-03-29
PH14029A (en) 1980-12-12
ZA771944B (en) 1978-03-29

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