CS199708B2 - Method of producing polypeptides and derivatives thereof having effect similar morphine - Google Patents

Method of producing polypeptides and derivatives thereof having effect similar morphine Download PDF

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Publication number
CS199708B2
CS199708B2 CS776017A CS601777A CS199708B2 CS 199708 B2 CS199708 B2 CS 199708B2 CS 776017 A CS776017 A CS 776017A CS 601777 A CS601777 A CS 601777A CS 199708 B2 CS199708 B2 CS 199708B2
Authority
CS
Czechoslovakia
Prior art keywords
mmol
gly
dissolved
residue
filtered
Prior art date
Application number
CS776017A
Other languages
Czech (cs)
English (en)
Inventor
Sandor Bajusz
Andras Ronai
Jozsef Szekely
Laszlo Graf
Zsuzsa Mihai
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of CS199708B2 publication Critical patent/CS199708B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/70—Enkephalins
    • C07K14/702—Enkephalins with at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CS776017A 1976-09-16 1977-09-15 Method of producing polypeptides and derivatives thereof having effect similar morphine CS199708B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU76GO1350A HU178001B (en) 1976-09-16 1976-09-16 Process for preparing new pentapeptides with morphine-like activity and derivatives thereof

Publications (1)

Publication Number Publication Date
CS199708B2 true CS199708B2 (en) 1980-07-31

Family

ID=10996820

Family Applications (1)

Application Number Title Priority Date Filing Date
CS776017A CS199708B2 (en) 1976-09-16 1977-09-15 Method of producing polypeptides and derivatives thereof having effect similar morphine

Country Status (16)

Country Link
US (1) US4465625A (fr)
JP (1) JPS602319B2 (fr)
AT (1) AT360184B (fr)
BE (1) BE858453A (fr)
CH (1) CH636599A5 (fr)
CS (1) CS199708B2 (fr)
DD (1) DD132127A5 (fr)
DE (1) DE2740699A1 (fr)
DK (1) DK149077C (fr)
FR (1) FR2364890A1 (fr)
GB (1) GB1584968A (fr)
HU (1) HU178001B (fr)
NL (1) NL7709636A (fr)
PL (1) PL114062B1 (fr)
SE (1) SE440658B (fr)
SU (1) SU772481A3 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2353040A1 (fr) * 1976-05-25 1977-12-23 Europ Propulsion Allumeur pour bloc de poudres propulsives
FR2359817A1 (fr) * 1976-07-27 1978-02-24 Reckitt & Colmann Prod Ltd Nouveaux peptides, leur procede de preparation et composition therapeutique les contenant
US4259234A (en) * 1976-09-27 1981-03-31 Eli Lilly And Company Analgesic compounds
GB2000784B (en) * 1977-07-05 1982-01-20 American Home Prod Analgesic polypetide
JPS5424850A (en) * 1977-07-22 1979-02-24 Wellcome Found Peptide compound
GB1604850A (en) * 1977-11-24 1981-12-16 Wellcome Found Biologically active peptides
FR2424253A1 (fr) * 1978-04-27 1979-11-23 Brun Lab Sa Le Nouveaux derives de peptides analogues des enkephalines, leur procede de preparation et leur application therapeutique
NL8005121A (nl) * 1979-09-20 1981-03-24 Erba Farmitalia Biologisch actieve peptiden.
HU181013B (en) * 1980-01-25 1983-05-30 Gyogyszerkutato Intezet Process for preparing new enkephalin analogues
WO1982000640A1 (fr) * 1980-08-18 1982-03-04 Akita T Derives de tripeptides alkylamide
DE3333752A1 (de) * 1983-09-19 1985-04-11 Victor Dipl.- Chem. 8000 München Brantl Pharmakologisch aktive peptide

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2703109A1 (de) * 1976-01-26 1977-08-04 Wellcome Found Biologisch wirksame amide
GB1532181A (en) * 1976-02-02 1978-11-15 Beckman Instruments Inc Pentapetides and a method of preparing them
NZ183712A (en) * 1976-04-08 1979-10-25 Ici Ltd Polypeptide analogues of enkephalins, and pharmaceutical compositions
DE2732451A1 (de) * 1976-07-27 1978-02-02 Reckitt & Colmann Prod Ltd Peptidverbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneipraeparate
US4259234A (en) * 1976-09-27 1981-03-31 Eli Lilly And Company Analgesic compounds
JPS5424850A (en) * 1977-07-22 1979-02-24 Wellcome Found Peptide compound

Also Published As

Publication number Publication date
HU178001B (en) 1982-02-28
GB1584968A (en) 1981-02-18
DK409277A (da) 1978-03-17
BE858453A (fr) 1978-03-07
JPS5340735A (en) 1978-04-13
DK149077C (da) 1986-06-16
ATA632377A (de) 1980-05-15
CH636599A5 (en) 1983-06-15
FR2364890B1 (fr) 1984-03-23
DK149077B (da) 1986-01-13
AT360184B (de) 1980-12-29
JPS602319B2 (ja) 1985-01-21
DE2740699A1 (de) 1978-03-23
PL200857A1 (pl) 1979-06-04
SE7709913L (sv) 1978-03-17
DD132127A5 (de) 1978-08-30
DE2740699C2 (fr) 1987-10-01
NL7709636A (nl) 1978-03-20
SE440658B (sv) 1985-08-12
FR2364890A1 (fr) 1978-04-14
US4465625A (en) 1984-08-14
SU772481A3 (ru) 1980-10-15
PL114062B1 (en) 1981-01-31

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