CS195350B2 - Method of producing 3-alkyl-5-isoquinolyliminothiazolo/3,4-b/isoquinolines - Google Patents

Method of producing 3-alkyl-5-isoquinolyliminothiazolo/3,4-b/isoquinolines Download PDF

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Publication number
CS195350B2
CS195350B2 CS785983A CS598378A CS195350B2 CS 195350 B2 CS195350 B2 CS 195350B2 CS 785983 A CS785983 A CS 785983A CS 598378 A CS598378 A CS 598378A CS 195350 B2 CS195350 B2 CS 195350B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
optionally
isoquinoline
acid
tetrahydroisoquinoline
Prior art date
Application number
CS785983A
Other languages
Czech (cs)
English (en)
Inventor
Daniel Farge
Alain Jossin
Gerard Ponsinet
Daniel Reisdorf
Original Assignee
Rhone Poulenc Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7701516A external-priority patent/FR2378030A1/fr
Priority claimed from FR7739028A external-priority patent/FR2412545A1/fr
Application filed by Rhone Poulenc Ind filed Critical Rhone Poulenc Ind
Publication of CS195350B2 publication Critical patent/CS195350B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
CS785983A 1977-01-20 1978-01-17 Method of producing 3-alkyl-5-isoquinolyliminothiazolo/3,4-b/isoquinolines CS195350B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7701516A FR2378030A1 (fr) 1977-01-20 1977-01-20 Nouveau derive de l'isoquinoleine, sa preparation et les compositions qui le contiennent
FR7739028A FR2412545A1 (fr) 1977-12-23 1977-12-23 Nouveaux derives de l'isoquinoleine, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
CS195350B2 true CS195350B2 (en) 1980-01-31

Family

ID=26219809

Family Applications (2)

Application Number Title Priority Date Filing Date
CS785983A CS195350B2 (en) 1977-01-20 1978-01-17 Method of producing 3-alkyl-5-isoquinolyliminothiazolo/3,4-b/isoquinolines
CS78323A CS195349B2 (en) 1977-01-20 1978-01-17 Method of producing 3-alkyl-5-isoquinolyliminothiazolo/3,4-b/isoquinolines

Family Applications After (1)

Application Number Title Priority Date Filing Date
CS78323A CS195349B2 (en) 1977-01-20 1978-01-17 Method of producing 3-alkyl-5-isoquinolyliminothiazolo/3,4-b/isoquinolines

Country Status (25)

Country Link
US (1) US4153698A (es)
JP (1) JPS5914037B2 (es)
AR (2) AR217460A1 (es)
AT (1) AT361481B (es)
AU (1) AU510044B2 (es)
CA (1) CA1091674A (es)
CH (1) CH633010A5 (es)
CS (2) CS195350B2 (es)
DE (1) DE2802453C3 (es)
DK (1) DK143343C (es)
ES (2) ES466192A1 (es)
FI (1) FI62314C (es)
GB (1) GB1574281A (es)
GR (1) GR61726B (es)
HU (1) HU174219B (es)
IE (1) IE46375B1 (es)
IL (1) IL53841A (es)
LU (1) LU78895A1 (es)
NL (1) NL7800383A (es)
NO (1) NO780202L (es)
NZ (1) NZ186282A (es)
OA (1) OA05859A (es)
PT (1) PT67545B (es)
SE (1) SE7800681L (es)
SU (2) SU730309A3 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU797580A3 (ru) * 1977-11-10 1981-01-15 Рон-Пуленк Эндюстри (Фирма) Способ получени производных изохино-лиНА, иХ СОлЕй, РАцЕМАТОВ или ОпТичЕС-КиХ изОМЕРОВ
FR2456098A2 (fr) * 1977-12-23 1980-12-05 Rhone Poulenc Ind Nouveaux derives de l'isoquinoleine, leur preparation et les compositions pharmaceutiques qui les contiennent
NL7908655A (nl) * 1978-12-07 1980-06-10 Rhone Poulenc Ind Nieuwe thienopyridine-derivaten, de bereiding ervan, alsmede farmaceutische preparaten, die de nieuwe derivaten bevatten.
FR2456111A1 (fr) * 1979-05-09 1980-12-05 Rhone Poulenc Ind Nouveaux derives de l'indole, leur preparation et les medicaments qui les contiennent
NL8002540A (nl) * 1979-05-09 1980-11-11 Rhone Poulenc Ind Nieuwe isochinoline derivaten, werkwijzen ter bereiding ervan en farmaceutische preparaten, die de nieuwe derivaten bevatten.
US4363909A (en) 1979-12-04 1982-12-14 Rhone Poulenc Industries Thiazolo[3,4-b]isoquinolines
US4269842A (en) * 1979-12-05 1981-05-26 Rhone-Poulenc Industries Method for treating rhinoviral complaints
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL169076C (nl) * 1975-08-06 1982-06-01 Rhone Poulenc Ind Werkwijze voor het bereiden of vervaardigen van farmacologische preparaten met een analgetische en antipyretische werking, alsmede werkwijze voor het bereiden van geneeskrachtige verbindingen, welke geschikt zijn voor gebruik in dergelijke preparaten.

Also Published As

Publication number Publication date
SU776560A3 (ru) 1980-10-30
JPS53116399A (en) 1978-10-11
DE2802453A1 (de) 1978-07-27
NO780202L (no) 1978-07-21
JPS5914037B2 (ja) 1984-04-02
CA1091674A (fr) 1980-12-16
IL53841A (en) 1980-10-26
IE780126L (en) 1978-07-20
LU78895A1 (fr) 1978-09-18
FI780182A7 (fi) 1978-07-21
AU3261178A (en) 1979-08-02
PT67545B (fr) 1979-06-15
ES468630A1 (es) 1978-12-01
AR217460A1 (es) 1980-03-31
GB1574281A (en) 1980-09-03
FI62314B (fi) 1982-08-31
ES466192A1 (es) 1978-10-16
OA05859A (fr) 1981-05-31
DK143343C (da) 1982-01-25
DK27178A (da) 1978-07-21
IE46375B1 (en) 1983-05-18
SE7800681L (sv) 1978-07-21
CH633010A5 (fr) 1982-11-15
NL7800383A (nl) 1978-07-24
AU510044B2 (en) 1980-06-05
IL53841A0 (en) 1978-04-30
AR219963A1 (es) 1980-09-30
AT361481B (de) 1981-03-10
NZ186282A (en) 1980-02-21
DE2802453C3 (de) 1982-03-25
US4153698A (en) 1979-05-08
DE2802453B2 (de) 1981-04-02
GR61726B (en) 1978-12-29
ATA39378A (de) 1980-08-15
SU730309A3 (ru) 1980-04-25
CS195349B2 (en) 1980-01-31
HU174219B (hu) 1979-11-28
PT67545A (fr) 1978-02-01
DK143343B (da) 1981-08-10
FI62314C (fi) 1982-12-10

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