CS191322B2 - Process for preparing new disubstituted phenolethers of 3-amino-2-hydroxypropane - Google Patents

Process for preparing new disubstituted phenolethers of 3-amino-2-hydroxypropane

Info

Publication number
CS191322B2
CS191322B2 CS766837A CS683776A CS191322B2 CS 191322 B2 CS191322 B2 CS 191322B2 CS 766837 A CS766837 A CS 766837A CS 683776 A CS683776 A CS 683776A CS 191322 B2 CS191322 B2 CS 191322B2
Authority
CS
Czechoslovakia
Prior art keywords
phenolethers
hydroxypropane
amino
preparing new
new disubstituted
Prior art date
Application number
CS766837A
Other languages
Czech (cs)
English (en)
Inventor
Rudolf Hiltmann
Arend Heise
Stanislav Kazda
Friedich Hoffmeister
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of CS191322B2 publication Critical patent/CS191322B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/34Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/36Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by carbon atoms having at least two bonds to oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CS766837A 1975-10-23 1976-10-22 Process for preparing new disubstituted phenolethers of 3-amino-2-hydroxypropane CS191322B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752547524 DE2547524A1 (de) 1975-10-23 1975-10-23 Disubstituierte phenolaether des 3-amino-2-hydroxypropans, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
CS191322B2 true CS191322B2 (en) 1979-06-29

Family

ID=5959934

Family Applications (2)

Application Number Title Priority Date Filing Date
CS766837A CS191322B2 (en) 1975-10-23 1976-10-22 Process for preparing new disubstituted phenolethers of 3-amino-2-hydroxypropane
CS777809A CS191344B2 (en) 1975-10-23 1976-10-22 Method of producing novel disubstituted phenolethers of 3-amino-2-hydroxypropane

Family Applications After (1)

Application Number Title Priority Date Filing Date
CS777809A CS191344B2 (en) 1975-10-23 1976-10-22 Method of producing novel disubstituted phenolethers of 3-amino-2-hydroxypropane

Country Status (29)

Country Link
US (1) US4110472A (sv)
JP (1) JPS5935387B2 (sv)
AT (2) AT345792B (sv)
AU (1) AU502167B2 (sv)
BE (1) BE847541A (sv)
BG (2) BG31796A3 (sv)
CA (1) CA1085417A (sv)
CH (2) CH623562A5 (sv)
CS (2) CS191322B2 (sv)
DD (1) DD128555A5 (sv)
DE (1) DE2547524A1 (sv)
DK (1) DK480376A (sv)
ES (1) ES452616A1 (sv)
FI (1) FI67075C (sv)
FR (1) FR2328458A1 (sv)
GB (1) GB1497500A (sv)
GR (1) GR61598B (sv)
HU (1) HU174097B (sv)
IE (1) IE43745B1 (sv)
IL (1) IL50732A (sv)
LU (1) LU76057A1 (sv)
NL (1) NL7611683A (sv)
NO (1) NO143844C (sv)
PL (2) PL110002B1 (sv)
PT (1) PT65737B (sv)
RO (1) RO76883A (sv)
SE (1) SE432926B (sv)
SU (2) SU639443A3 (sv)
ZA (1) ZA766303B (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1223395B (it) * 1987-12-01 1990-09-19 Simes Composti ad attivita' cardiovascolare
US5541204A (en) * 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
US20090170841A1 (en) 2007-04-20 2009-07-02 Acucela Inc. Styrenyl Derivative Compounds for Treating Ophthalmic Diseases and Disorders
FR3030514A1 (fr) * 2014-12-18 2016-06-24 Centre De Coop Int En Rech Agronomique Pour Le Dev (Cirad) Dimeres polyaromatiques
EP3144289A1 (en) * 2015-09-16 2017-03-22 Evonik Technochemie GmbH [(2-ethoxy-5-trans-1-propen-1-yl)-phenoxyl]-terminated compounds
KR20190096949A (ko) 2016-10-05 2019-08-20 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 소분자 ampk 활성화제

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3758583A (en) * 1971-01-21 1973-09-11 Syntex Corp 2-(2-hydroxy-3-aminopropyl-1-yloxy)-1,6-dilfuoro-and-1,6-methano-{8 10{9 annulenes and the salts thereof

Also Published As

Publication number Publication date
RO76883A (ro) 1981-08-30
NO143844C (no) 1981-04-22
AU1879776A (en) 1978-04-27
PT65737B (en) 1978-04-20
JPS5935387B2 (ja) 1984-08-28
SE432926B (sv) 1984-04-30
DE2547524A1 (de) 1977-04-28
ATA784476A (de) 1977-12-15
ZA766303B (en) 1977-09-28
US4110472A (en) 1978-08-29
BG27732A3 (en) 1979-12-12
ATA606377A (de) 1978-02-15
JPS5251352A (en) 1977-04-25
CA1085417A (en) 1980-09-09
FR2328458A1 (fr) 1977-05-20
PL110002B1 (en) 1980-06-30
IE43745B1 (en) 1981-05-20
CH630058A5 (de) 1982-05-28
PL110007B1 (en) 1980-06-30
IL50732A (en) 1979-12-30
FR2328458B1 (sv) 1979-03-02
SE7611686L (sv) 1977-04-24
NO763442L (sv) 1977-04-26
NO143844B (no) 1981-01-12
CH623562A5 (sv) 1981-06-15
AT344682B (de) 1978-08-10
BE847541A (fr) 1977-04-22
HU174097B (hu) 1979-11-28
DK480376A (da) 1977-04-24
SU664559A3 (ru) 1979-05-25
PL193206A1 (pl) 1979-03-12
LU76057A1 (sv) 1977-05-31
ES452616A1 (es) 1978-01-16
PT65737A (en) 1976-11-01
IL50732A0 (en) 1976-12-31
SU639443A3 (ru) 1978-12-25
FI67075C (fi) 1985-01-10
GB1497500A (en) 1978-01-12
AU502167B2 (en) 1979-07-12
DD128555A5 (de) 1977-11-23
BG31796A3 (en) 1982-03-15
IE43745L (en) 1977-04-23
FI763010A (sv) 1977-04-24
FI67075B (fi) 1984-09-28
GR61598B (en) 1978-12-02
CS191344B2 (en) 1979-06-29
NL7611683A (nl) 1977-04-26
AT345792B (de) 1978-10-10

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