CR9149A - Derivados de rapamicina y los usos de los mismos en el tratamiento de trastornos neurologicos - Google Patents
Derivados de rapamicina y los usos de los mismos en el tratamiento de trastornos neurologicosInfo
- Publication number
- CR9149A CR9149A CR9149A CR9149A CR9149A CR 9149 A CR9149 A CR 9149A CR 9149 A CR9149 A CR 9149A CR 9149 A CR9149 A CR 9149A CR 9149 A CR9149 A CR 9149A
- Authority
- CR
- Costa Rica
- Prior art keywords
- treatment
- neurological disorders
- same
- rapamycin derivatives
- rapamycin
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/16—Central respiratory analeptics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Gynecology & Obstetrics (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Psychology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Pregnancy & Childbirth (AREA)
- Emergency Medicine (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
Abstract
La presente invencion proporciona productos de la estructura que se muestra en donde R1-R9, R15 y n son como se definio en la presente; estos compuestos son utiles en el tratamiento de trastornos neurologicos o complicaciones debidas a la apoplegia o lesion de la cabeza; y como agentes neuroprotectores y neurogenerativos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63800404P | 2004-12-20 | 2004-12-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
CR9149A true CR9149A (es) | 2007-10-23 |
Family
ID=36602218
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR9149A CR9149A (es) | 2004-12-20 | 2007-05-24 | Derivados de rapamicina y los usos de los mismos en el tratamiento de trastornos neurologicos |
Country Status (16)
Country | Link |
---|---|
US (3) | US7273874B2 (es) |
EP (1) | EP1828203A2 (es) |
JP (1) | JP2008524232A (es) |
KR (1) | KR20070090931A (es) |
CN (1) | CN101084226A (es) |
AU (1) | AU2005319427B2 (es) |
BR (1) | BRPI0519593A2 (es) |
CA (1) | CA2590254A1 (es) |
CR (1) | CR9149A (es) |
IL (1) | IL183772A0 (es) |
MX (1) | MX2007007409A (es) |
NI (1) | NI200700156A (es) |
NO (1) | NO20072665L (es) |
RU (1) | RU2007119585A (es) |
WO (1) | WO2006068905A2 (es) |
ZA (1) | ZA200705123B (es) |
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MX2007007409A (es) * | 2004-12-20 | 2007-07-12 | Wyeth Corp | Derivados de rapamicina y los usos de los mismos en el tratamiento de trastornos neurologicos. |
ES2380779T3 (es) * | 2004-12-20 | 2012-05-18 | Wyeth Llc | Análogos de rapamicina y usos de los mismos en el tratamiento de trastornos neurológicos, proliferativos e inflamatorios |
WO2006096529A2 (en) * | 2005-03-07 | 2006-09-14 | Novartis Ag | Genes involved in neurodegenerative conditions |
KR20080077618A (ko) * | 2005-12-07 | 2008-08-25 | 와이어쓰 | 정제된 결정체 cci-779 의 제조 방법 |
KR20080077147A (ko) * | 2005-12-07 | 2008-08-21 | 와이어쓰 | 결정성 라파마이신의 제조 방법 및 시차 주사 열량계를사용하는 라파마이신 화합물의 결정화도의 측정 방법 |
WO2007067560A2 (en) * | 2005-12-07 | 2007-06-14 | Wyeth | Scalable process for the preparation of a rapamycin 42-ester from a rapamycin 42-ester boronate |
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-
2005
- 2005-12-15 MX MX2007007409A patent/MX2007007409A/es active IP Right Grant
- 2005-12-15 CN CNA2005800437050A patent/CN101084226A/zh active Pending
- 2005-12-15 AU AU2005319427A patent/AU2005319427B2/en not_active Ceased
- 2005-12-15 BR BRPI0519593-4A patent/BRPI0519593A2/pt not_active IP Right Cessation
- 2005-12-15 US US11/300,941 patent/US7273874B2/en not_active Expired - Fee Related
- 2005-12-15 CA CA002590254A patent/CA2590254A1/en not_active Abandoned
- 2005-12-15 WO PCT/US2005/045331 patent/WO2006068905A2/en active Application Filing
- 2005-12-15 RU RU2007119585/04A patent/RU2007119585A/ru not_active Application Discontinuation
- 2005-12-15 JP JP2007546876A patent/JP2008524232A/ja active Pending
- 2005-12-15 EP EP05854115A patent/EP1828203A2/en not_active Withdrawn
- 2005-12-15 KR KR1020077013852A patent/KR20070090931A/ko not_active Application Discontinuation
-
2007
- 2007-05-24 CR CR9149A patent/CR9149A/es not_active Application Discontinuation
- 2007-05-25 NO NO20072665A patent/NO20072665L/no not_active Application Discontinuation
- 2007-06-07 IL IL183772A patent/IL183772A0/en unknown
- 2007-06-18 NI NI200700156A patent/NI200700156A/es unknown
- 2007-06-19 ZA ZA200705123A patent/ZA200705123B/xx unknown
- 2007-08-14 US US11/891,879 patent/US7476678B2/en not_active Expired - Fee Related
-
2008
- 2008-12-05 US US12/329,106 patent/US20090088448A1/en not_active Abandoned
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KR20070090931A (ko) | 2007-09-06 |
US20090088448A1 (en) | 2009-04-02 |
US7273874B2 (en) | 2007-09-25 |
MX2007007409A (es) | 2007-07-12 |
AU2005319427A1 (en) | 2006-06-29 |
US20060135550A1 (en) | 2006-06-22 |
WO2006068905A2 (en) | 2006-06-29 |
RU2007119585A (ru) | 2009-01-27 |
BRPI0519593A2 (pt) | 2009-02-25 |
NI200700156A (es) | 2008-06-17 |
IL183772A0 (en) | 2007-09-20 |
US7476678B2 (en) | 2009-01-13 |
CA2590254A1 (en) | 2006-06-29 |
CN101084226A (zh) | 2007-12-05 |
NO20072665L (no) | 2007-09-07 |
ZA200705123B (en) | 2010-01-27 |
JP2008524232A (ja) | 2008-07-10 |
US20080027089A1 (en) | 2008-01-31 |
AU2005319427B2 (en) | 2011-11-03 |
WO2006068905A3 (en) | 2006-12-07 |
EP1828203A2 (en) | 2007-09-05 |
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