CR9149A - Derivados de rapamicina y los usos de los mismos en el tratamiento de trastornos neurologicos - Google Patents
Derivados de rapamicina y los usos de los mismos en el tratamiento de trastornos neurologicosInfo
- Publication number
- CR9149A CR9149A CR9149A CR9149A CR9149A CR 9149 A CR9149 A CR 9149A CR 9149 A CR9149 A CR 9149A CR 9149 A CR9149 A CR 9149A CR 9149 A CR9149 A CR 9149A
- Authority
- CR
- Costa Rica
- Prior art keywords
- treatment
- neurological disorders
- same
- rapamycin derivatives
- rapamycin
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/16—Central respiratory analeptics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gynecology & Obstetrics (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Anesthesiology (AREA)
- Emergency Medicine (AREA)
- Pregnancy & Childbirth (AREA)
- Vascular Medicine (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
Abstract
La presente invencion proporciona productos de la estructura que se muestra en donde R1-R9, R15 y n son como se definio en la presente; estos compuestos son utiles en el tratamiento de trastornos neurologicos o complicaciones debidas a la apoplegia o lesion de la cabeza; y como agentes neuroprotectores y neurogenerativos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63800404P | 2004-12-20 | 2004-12-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
CR9149A true CR9149A (es) | 2007-10-23 |
Family
ID=36602218
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR9149A CR9149A (es) | 2004-12-20 | 2007-05-24 | Derivados de rapamicina y los usos de los mismos en el tratamiento de trastornos neurologicos |
Country Status (16)
Country | Link |
---|---|
US (3) | US7273874B2 (es) |
EP (1) | EP1828203A2 (es) |
JP (1) | JP2008524232A (es) |
KR (1) | KR20070090931A (es) |
CN (1) | CN101084226A (es) |
AU (1) | AU2005319427B2 (es) |
BR (1) | BRPI0519593A2 (es) |
CA (1) | CA2590254A1 (es) |
CR (1) | CR9149A (es) |
IL (1) | IL183772A0 (es) |
MX (1) | MX2007007409A (es) |
NI (1) | NI200700156A (es) |
NO (1) | NO20072665L (es) |
RU (1) | RU2007119585A (es) |
WO (1) | WO2006068905A2 (es) |
ZA (1) | ZA200705123B (es) |
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RU2007119585A (ru) * | 2004-12-20 | 2009-01-27 | Вайет (Us) | Производные рапамицина и их применение при лечении неврологических заболеваний |
EP1828202B1 (en) * | 2004-12-20 | 2012-03-14 | Wyeth LLC | Rapamcyin analogues and the uses thereof in the treatment of neurological, proliferative and inflammatory disorders |
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TW200736603A (en) * | 2005-12-07 | 2007-10-01 | Wyeth Corp | Methods for preparing crystalline rapamycin and measuring crystallinity of rapamycin compounds using differential scanning calorimetry |
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KR101666228B1 (ko) | 2007-09-28 | 2016-10-13 | 인트렉손 코포레이션 | 생물치료학적 분자를 발현시키기 위한 치료학적 유전자-스위치 작제물 및 생물반응기, 및 이의 용도 |
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CN102292078A (zh) | 2008-11-11 | 2011-12-21 | 得克萨斯大学体系董事会 | 哺乳动物雷帕霉素靶蛋白的抑制 |
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-
2005
- 2005-12-15 RU RU2007119585/04A patent/RU2007119585A/ru not_active Application Discontinuation
- 2005-12-15 MX MX2007007409A patent/MX2007007409A/es active IP Right Grant
- 2005-12-15 KR KR1020077013852A patent/KR20070090931A/ko not_active Application Discontinuation
- 2005-12-15 EP EP05854115A patent/EP1828203A2/en not_active Withdrawn
- 2005-12-15 CA CA002590254A patent/CA2590254A1/en not_active Abandoned
- 2005-12-15 US US11/300,941 patent/US7273874B2/en not_active Expired - Fee Related
- 2005-12-15 BR BRPI0519593-4A patent/BRPI0519593A2/pt not_active IP Right Cessation
- 2005-12-15 WO PCT/US2005/045331 patent/WO2006068905A2/en active Application Filing
- 2005-12-15 CN CNA2005800437050A patent/CN101084226A/zh active Pending
- 2005-12-15 AU AU2005319427A patent/AU2005319427B2/en not_active Ceased
- 2005-12-15 JP JP2007546876A patent/JP2008524232A/ja active Pending
-
2007
- 2007-05-24 CR CR9149A patent/CR9149A/es not_active Application Discontinuation
- 2007-05-25 NO NO20072665A patent/NO20072665L/no not_active Application Discontinuation
- 2007-06-07 IL IL183772A patent/IL183772A0/en unknown
- 2007-06-18 NI NI200700156A patent/NI200700156A/es unknown
- 2007-06-19 ZA ZA200705123A patent/ZA200705123B/xx unknown
- 2007-08-14 US US11/891,879 patent/US7476678B2/en not_active Expired - Fee Related
-
2008
- 2008-12-05 US US12/329,106 patent/US20090088448A1/en not_active Abandoned
Also Published As
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JP2008524232A (ja) | 2008-07-10 |
US7476678B2 (en) | 2009-01-13 |
IL183772A0 (en) | 2007-09-20 |
KR20070090931A (ko) | 2007-09-06 |
AU2005319427A1 (en) | 2006-06-29 |
NI200700156A (es) | 2008-06-17 |
US20090088448A1 (en) | 2009-04-02 |
WO2006068905A3 (en) | 2006-12-07 |
NO20072665L (no) | 2007-09-07 |
MX2007007409A (es) | 2007-07-12 |
ZA200705123B (en) | 2010-01-27 |
US20080027089A1 (en) | 2008-01-31 |
US20060135550A1 (en) | 2006-06-22 |
AU2005319427B2 (en) | 2011-11-03 |
RU2007119585A (ru) | 2009-01-27 |
EP1828203A2 (en) | 2007-09-05 |
CN101084226A (zh) | 2007-12-05 |
BRPI0519593A2 (pt) | 2009-02-25 |
US7273874B2 (en) | 2007-09-25 |
WO2006068905A2 (en) | 2006-06-29 |
CA2590254A1 (en) | 2006-06-29 |
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