CR8771A - Inhibidor de 11-beta-hidroxi esteroide deshidrogenasa tipo 1 - Google Patents
Inhibidor de 11-beta-hidroxi esteroide deshidrogenasa tipo 1Info
- Publication number
- CR8771A CR8771A CR8771A CR8771A CR8771A CR 8771 A CR8771 A CR 8771A CR 8771 A CR8771 A CR 8771A CR 8771 A CR8771 A CR 8771A CR 8771 A CR8771 A CR 8771A
- Authority
- CR
- Costa Rica
- Prior art keywords
- hydroxi
- beta
- inhibitor
- dehydrogenase type
- steroid dehydrogenase
- Prior art date
Links
- 101710088194 Dehydrogenase Proteins 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title 1
- 150000003431 steroids Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- KVUXYQHEESDGIJ-UHFFFAOYSA-N 10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthrene-3,16-diol Chemical compound C1CC2CC(O)CCC2(C)C2C1C1CC(O)CC1(C)CC2 KVUXYQHEESDGIJ-UHFFFAOYSA-N 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/48—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
La presente invencion se refiere a compuestos con la formula (I), ( II ), ( III ) o ( IV), en los cuales R1,R2,R3,R4,R5,R6,R7, X y Z son como se define aqui y ademas a composiciones farmaceuticas que comprenden los compuestos, como tambien metodos de uso de los compuestos para el tratamiento de transtornos asociados con la enzima deshidrogenasa 11-B- hidroxiesteroide tipo 1 y para la preparacion de un medicamento que actua sobre la enzima deshidrogenasa 11-b- hidroxiesteroide tipo 1 humana.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0401324A SE0401324D0 (sv) | 2004-05-24 | 2004-05-24 | New compounds |
SE0402509A SE0402509D0 (sv) | 2004-10-15 | 2004-10-15 | New compounds |
US65077705P | 2005-01-31 | 2005-01-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
CR8771A true CR8771A (es) | 2007-07-24 |
Family
ID=41717469
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR8771A CR8771A (es) | 2004-05-24 | 2006-11-24 | Inhibidor de 11-beta-hidroxi esteroide deshidrogenasa tipo 1 |
CR20120420A CR20120420A (es) | 2004-05-24 | 2012-08-10 | Inhibidor de 11-beta-hidroxi exteroide deshidrogenasa tipo 1 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR20120420A CR20120420A (es) | 2004-05-24 | 2012-08-10 | Inhibidor de 11-beta-hidroxi exteroide deshidrogenasa tipo 1 |
Country Status (10)
Country | Link |
---|---|
KR (1) | KR101296408B1 (es) |
CR (2) | CR8771A (es) |
EC (1) | ECSP067108A (es) |
HK (1) | HK1096095A1 (es) |
HR (1) | HRP20060456A2 (es) |
IL (1) | IL179167A (es) |
MA (1) | MA28662B1 (es) |
MX (1) | MXPA06013657A (es) |
NO (1) | NO20065781L (es) |
NZ (1) | NZ552284A (es) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ302691B6 (cs) | 1998-07-08 | 2011-09-07 | Sanofi - Aventis Deutschland GmbH | N-Arylamidová sloucenina, zpusob její prípravy, farmaceutický prostredek tuto slouceninu obsahující, tato sloucenina pro použití jako aktivátor a pro použití k terapii nebo profylaxi |
-
2005
- 2005-05-24 KR KR1020067026575A patent/KR101296408B1/ko not_active IP Right Cessation
- 2005-05-24 MX MXPA06013657A patent/MXPA06013657A/es active IP Right Grant
- 2005-05-24 NZ NZ552284A patent/NZ552284A/en not_active IP Right Cessation
-
2006
- 2006-11-09 IL IL179167A patent/IL179167A/en not_active IP Right Cessation
- 2006-11-24 CR CR8771A patent/CR8771A/es unknown
- 2006-12-13 NO NO20065781A patent/NO20065781L/no not_active Application Discontinuation
- 2006-12-14 MA MA29529A patent/MA28662B1/fr unknown
- 2006-12-21 EC EC2006007108A patent/ECSP067108A/es unknown
- 2006-12-21 HR HR20060456A patent/HRP20060456A2/xx not_active Application Discontinuation
-
2007
- 2007-03-26 HK HK07103229.0A patent/HK1096095A1/xx not_active IP Right Cessation
-
2012
- 2012-08-10 CR CR20120420A patent/CR20120420A/es unknown
Also Published As
Publication number | Publication date |
---|---|
NO20065781L (no) | 2007-02-08 |
NZ552284A (en) | 2010-01-29 |
ECSP067108A (es) | 2007-05-30 |
CR20120420A (es) | 2012-09-14 |
IL179167A (en) | 2012-01-31 |
HK1096095A1 (en) | 2007-05-25 |
MA28662B1 (fr) | 2007-06-01 |
IL179167A0 (en) | 2007-03-08 |
KR101296408B1 (ko) | 2013-08-13 |
HRP20060456A2 (en) | 2007-03-31 |
KR20070058382A (ko) | 2007-06-08 |
MXPA06013657A (es) | 2007-11-07 |
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