CR20120420A - Inhibidor de 11-beta-hidroxi exteroide deshidrogenasa tipo 1 - Google Patents

Inhibidor de 11-beta-hidroxi exteroide deshidrogenasa tipo 1

Info

Publication number
CR20120420A
CR20120420A CR20120420A CR20120420A CR20120420A CR 20120420 A CR20120420 A CR 20120420A CR 20120420 A CR20120420 A CR 20120420A CR 20120420 A CR20120420 A CR 20120420A CR 20120420 A CR20120420 A CR 20120420A
Authority
CR
Costa Rica
Prior art keywords
exteroid
hydroxi
beta
inhibitor
dehydrogenase type
Prior art date
Application number
CR20120420A
Other languages
English (en)
Inventor
Martin Henriksson
Evert Homan
Lars Johansson
Jerk Vallgarda
Meredith Williams
Eric Bercot
Christopher H Fotsch
Aiwen Li
Guolin Cai
Randall W Hungate
Chester Chenguang Yuan
Chirstopher Tegley
Jean David St
Nianhe Han
Qi Huang
Qingyian Liu
Michael D Bartberger
George A Moniz
Matthew J Frizzle
Original Assignee
Amgen Inc
Sanofi Aventis
Vimar Spa
Biovitrum Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0401324A external-priority patent/SE0401324D0/xx
Priority claimed from SE0402509A external-priority patent/SE0402509D0/xx
Application filed by Amgen Inc, Sanofi Aventis, Vimar Spa, Biovitrum Ab filed Critical Amgen Inc
Publication of CR20120420A publication Critical patent/CR20120420A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/48—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La presente invención no esta limitada al alcance de los aspectos ejemplificados que se buscan como ilustraciones de aspectos individuales de la invención.
CR20120420A 2004-05-24 2012-08-10 Inhibidor de 11-beta-hidroxi exteroide deshidrogenasa tipo 1 CR20120420A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0401324A SE0401324D0 (sv) 2004-05-24 2004-05-24 New compounds
SE0402509A SE0402509D0 (sv) 2004-10-15 2004-10-15 New compounds
US65077705P 2005-01-31 2005-01-31

Publications (1)

Publication Number Publication Date
CR20120420A true CR20120420A (es) 2012-09-14

Family

ID=41717469

Family Applications (2)

Application Number Title Priority Date Filing Date
CR8771A CR8771A (es) 2004-05-24 2006-11-24 Inhibidor de 11-beta-hidroxi esteroide deshidrogenasa tipo 1
CR20120420A CR20120420A (es) 2004-05-24 2012-08-10 Inhibidor de 11-beta-hidroxi exteroide deshidrogenasa tipo 1

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CR8771A CR8771A (es) 2004-05-24 2006-11-24 Inhibidor de 11-beta-hidroxi esteroide deshidrogenasa tipo 1

Country Status (10)

Country Link
KR (1) KR101296408B1 (es)
CR (2) CR8771A (es)
EC (1) ECSP067108A (es)
HK (1) HK1096095A1 (es)
HR (1) HRP20060456A2 (es)
IL (1) IL179167A (es)
MA (1) MA28662B1 (es)
MX (1) MXPA06013657A (es)
NO (1) NO20065781L (es)
NZ (1) NZ552284A (es)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU228111B1 (en) 1998-07-08 2012-11-28 Sanofi Aventis Deutschland Sulfur substituted sulfonylaminocarboxylic acid n-arylamides, their preparation, their use and pharmaceutical preparations comprising them

Also Published As

Publication number Publication date
HRP20060456A2 (en) 2007-03-31
IL179167A0 (en) 2007-03-08
HK1096095A1 (en) 2007-05-25
CR8771A (es) 2007-07-24
KR20070058382A (ko) 2007-06-08
MA28662B1 (fr) 2007-06-01
IL179167A (en) 2012-01-31
MXPA06013657A (es) 2007-11-07
NZ552284A (en) 2010-01-29
ECSP067108A (es) 2007-05-30
NO20065781L (no) 2007-02-08
KR101296408B1 (ko) 2013-08-13

Similar Documents

Publication Publication Date Title
CY1109911T1 (el) Πυρρολοβενζοδιαζεπινες
BRPI0411528A (pt) uso de isomalte como prebiótico
CR10662A (es) Compuestos de metilpiridopirimidinona
ECSP066893A (es) Inhibidores de proteínas de apoptosis (iap)
CR20130455A (es) Composiciones para el tratamiento de tumores
BRPI0520870B8 (pt) compostos intermediários para a preparação de alfa-mercaptoacetanilidas de s-triazolila
PA8671301A1 (es) Pirrolopiridinas sustituidas, composiciones que las contienen, proceso de fabricación y utilización
PA8809001A1 (es) Compuestos organicos
ECSP099413A (es) COMPUESTOS A BASE DE 4 - fenil - 6 - (2,2,2 - trifluoro - 1 - feniletoxi)pirimidina Y MÉTODOS PARA SU EMPLEO
UY29927A1 (es) Derivados sustituidos de la 5-fenil-2-tioxo-imidazolin-4-ona y de la 5-fenil-2-amino-imidazolidin-4-ona y sus sales, composiciones y aplicaciones
CY1112102T1 (el) Υποκατεστημενες πυριμιδοδιαζεπινες χρησιμες ως αναστολεις plk1
GT200500238A (es) Fenilaminotiazoles sustituidos y su uso
ECSP10010344A (es) Azolilmetiloxiranos, su uso y agentes que los contienen
GT201200339A (es) Compuestos, composiciones de tioacetato y mètodos de uso
CR11861A (es) Compuestos organicos
PA8663901A1 (es) Derivados del (1,5-difenil-1h-pirazol-3-il)oxadiazol, su prepararacion y su aplicacion en terapéutica
EA200702510A1 (ru) Способы защиты от апоптоза с применением липопептидов
UY31563A1 (es) Azolilmetiloxiranos, su uso y agentes que los contienen
ATE471324T1 (de) Triazolophthalazine
UY31562A1 (es) Azolilmetiloxiranos, su uso y agentes que los contienen
CR20110220A (es) Arilciclohexiléteres de dihidro-tetraazabenzoazuleno
UY31560A1 (es) Azolilmetiloxiranos, su uso y agentes que los contienen
DOP2005000010A (es) Inhibidores de quinasa
HN2010000330A (es) DERIVADOS DE INDOL-2-ONA DISUSTITUIDOS EN 3 y SU PREPARACION
NO20060896L (no) Alfa-aminoamidderivater nyttige som antiinflammatoriske midler