HRP20060456A2 - Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 - Google Patents

Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1

Info

Publication number
HRP20060456A2
HRP20060456A2 HR20060456A HRP20060456A HRP20060456A2 HR P20060456 A2 HRP20060456 A2 HR P20060456A2 HR 20060456 A HR20060456 A HR 20060456A HR P20060456 A HRP20060456 A HR P20060456A HR P20060456 A2 HRP20060456 A2 HR P20060456A2
Authority
HR
Croatia
Prior art keywords
dehydrogenase type
inhibitors
beta
steroid dehydrogenase
hydroxy steroid
Prior art date
Application number
HR20060456A
Other languages
English (en)
Croatian (hr)
Inventor
Henriksson Martin
Homan Evert
Johansson Lars
Vallgarda Jerk
Williams Meredith
Bercot Eric
H. Fotsch Cristopher
Li Aiwen
Cai Goulin
W. Hungate Randall
Chenguang Yuan Chester
Tegley Chirstopher
St.Jean David
Han Nianhe
Huang Qi
Liu Qingyian
D. Bartberger Michael
A. Moniz George
J. Frizzle Matthew
Original Assignee
Amgen
Biovitrum Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0401324A external-priority patent/SE0401324D0/xx
Priority claimed from SE0402509A external-priority patent/SE0402509D0/xx
Priority claimed from PCT/US2005/018081 external-priority patent/WO2005116002A2/en
Application filed by Amgen, Biovitrum Ab filed Critical Amgen
Publication of HRP20060456A2 publication Critical patent/HRP20060456A2/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/48Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/42Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HR20060456A 2004-05-24 2006-12-21 Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 HRP20060456A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE0401324A SE0401324D0 (sv) 2004-05-24 2004-05-24 New compounds
SE0402509A SE0402509D0 (sv) 2004-10-15 2004-10-15 New compounds
US65077705P 2005-01-31 2005-01-31
PCT/US2005/018081 WO2005116002A2 (en) 2004-05-24 2005-05-24 Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1

Publications (1)

Publication Number Publication Date
HRP20060456A2 true HRP20060456A2 (en) 2007-03-31

Family

ID=41717469

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20060456A HRP20060456A2 (en) 2004-05-24 2006-12-21 Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1

Country Status (10)

Country Link
KR (1) KR101296408B1 (xx)
CR (2) CR8771A (xx)
EC (1) ECSP067108A (xx)
HK (1) HK1096095A1 (xx)
HR (1) HRP20060456A2 (xx)
IL (1) IL179167A (xx)
MA (1) MA28662B1 (xx)
MX (1) MXPA06013657A (xx)
NO (1) NO20065781L (xx)
NZ (1) NZ552284A (xx)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1332943C (zh) 1998-07-08 2007-08-22 萨诺费-阿文蒂斯德国有限公司 硫取代的磺酰基氨基羧酸n-芳基酰胺,其制备方法、用途以及含有该化合物的药物制剂

Also Published As

Publication number Publication date
NZ552284A (en) 2010-01-29
IL179167A (en) 2012-01-31
ECSP067108A (es) 2007-05-30
IL179167A0 (en) 2007-03-08
NO20065781L (no) 2007-02-08
CR20120420A (es) 2012-09-14
MA28662B1 (fr) 2007-06-01
HK1096095A1 (en) 2007-05-25
MXPA06013657A (es) 2007-11-07
CR8771A (es) 2007-07-24
KR101296408B1 (ko) 2013-08-13
KR20070058382A (ko) 2007-06-08

Similar Documents

Publication Publication Date Title
TW200609227A (en) Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
NO20042596L (no) Inbibitorer av 11-beta-hydroksy steroid dehydrogenase type 1
NO20050851L (no) Kaspase-inhibitorer og anvendelser derav
SE0001899D0 (sv) New compounds
MXPA04004842A (es) Inhibidores de 11-(-hidroxiesteroide deshidrogenasa de tipo 1.
MXPA04004837A (es) Inhibidores de 11-??-hidroxiesteroide deshidrogenasa de tipo 1.
IS7925A (is) Hýdroxýetýlamínafleiður til að meðhöndla Alzheimers-sjúkdóm
MY137053A (en) Pyrimidine derivatives and their use as cb2 modulators
WO2005013892A3 (en) Hydrolytically-resistant boron-containing therapeutics and methods of use
EA200870216A1 (ru) Амидо соединения и их применение в качестве лекарственных средств
GB0222495D0 (en) Compounds
NO20070224L (no) 2-karbamid-4-fenyltiazolderivater, fremstilling og terapeutisk anvendelse derav
NO20064238L (no) Imidazolinderivater med CB1 agonistlsk aktivitet
SG151329A1 (en) Amido compounds and their use as pharmaceuticals
EA200501268A1 (ru) Ингибирующие вич 1,2,4-триазины
DK1778680T3 (da) Spirocykliske cyclohexaderivater
ATE457027T1 (de) Substituierte 1,4,8-triazaspiroä4.5 decan-2-on- verbindungen zur behandlung von fettsucht
TN2009000483A1 (fr) Derives de 7-alkynyl-1-8-naphthyridones, leur preparation et leur application en therapeutique
ATE491446T1 (de) Ligustilid zur behandlung von erkrankungen des zentralen nervensystems
RS44204A (xx) Inhibitori 11-beta- hidroksistereoidne dehidrogenaze tipa 1
BRPI0417476A (pt) derivados de indol hidroxietilamina tricìclica e seu uso no tratamento da doença de alzheimer
TNSN05291A1 (en) Sulfamate benzothiophene derivatives as steroid sulfatase inhibitors
TW200800966A (en) Beta-secretase modulators and methods of use
RS44304A (xx) Inhibitori 11-beta- hidroksistereoidne dehidrogenaze tipa 1
HRP20060456A2 (en) Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1

Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
ODRP Renewal fee for the maintenance of a patent

Payment date: 20130409

Year of fee payment: 9

ODBI Application refused