CR8590A - Metodos para elaborar morfinotas 3-0 protegidas carboxilatos de dienol, morfinota 3-0 protegidos - Google Patents
Metodos para elaborar morfinotas 3-0 protegidas carboxilatos de dienol, morfinota 3-0 protegidosInfo
- Publication number
- CR8590A CR8590A CR8590A CR8590A CR8590A CR 8590 A CR8590 A CR 8590A CR 8590 A CR8590 A CR 8590A CR 8590 A CR8590 A CR 8590A CR 8590 A CR8590 A CR 8590A
- Authority
- CR
- Costa Rica
- Prior art keywords
- protected
- methods
- morphinots
- morphinot
- dienol
- Prior art date
Links
- 150000007942 carboxylates Chemical class 0.000 title 1
- NFDFQCUYFHCNBW-SCGPFSFSSA-N dienestrol Chemical compound C=1C=C(O)C=CC=1\C(=C/C)\C(=C\C)\C1=CC=C(O)C=C1 NFDFQCUYFHCNBW-SCGPFSFSSA-N 0.000 title 1
- YRIZYWQGELRKNT-UHFFFAOYSA-N 1,3,5-trichloro-1,3,5-triazinane-2,4,6-trione Chemical compound ClN1C(=O)N(Cl)C(=O)N(Cl)C1=O YRIZYWQGELRKNT-UHFFFAOYSA-N 0.000 abstract 1
- 150000001299 aldehydes Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 150000003138 primary alcohols Chemical class 0.000 abstract 1
- 150000003333 secondary alcohols Chemical class 0.000 abstract 1
- 229950009390 symclosene Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
Se describen metodos para elaborar aldehidos y cetonas que comprenden permitir que el alcohol primario o secundario correspondiente reaccione en presencia de un acido tricloroisocianurico, un compuesto de Formula R1SR2 y una base.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54271104P | 2004-02-06 | 2004-02-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
CR8590A true CR8590A (es) | 2007-07-19 |
Family
ID=34860329
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR8590A CR8590A (es) | 2004-02-06 | 2006-09-01 | Metodos para elaborar morfinotas 3-0 protegidas carboxilatos de dienol, morfinota 3-0 protegidos |
Country Status (34)
Country | Link |
---|---|
US (6) | US8003793B2 (es) |
EP (3) | EP1711502B1 (es) |
JP (1) | JP4963968B2 (es) |
KR (4) | KR20070108956A (es) |
CN (1) | CN1918168B (es) |
AP (1) | AP2006003716A0 (es) |
AT (2) | ATE406372T1 (es) |
AU (1) | AU2005212258B2 (es) |
BR (1) | BRPI0506607B8 (es) |
CA (2) | CA2808199C (es) |
CR (1) | CR8590A (es) |
CY (2) | CY1108506T1 (es) |
DE (2) | DE602005018265D1 (es) |
DK (2) | DK1864987T3 (es) |
EA (2) | EA012905B1 (es) |
EC (1) | ECSP066824A (es) |
ES (2) | ES2313299T3 (es) |
GE (1) | GEP20084454B (es) |
HK (2) | HK1119160A1 (es) |
HR (2) | HRP20080618T3 (es) |
IL (2) | IL177281A (es) |
MA (1) | MA28346A1 (es) |
MX (1) | MXPA06008931A (es) |
NO (2) | NO20063989L (es) |
NZ (2) | NZ548786A (es) |
PL (2) | PL1711502T3 (es) |
PT (2) | PT1711502E (es) |
RS (2) | RS50663B (es) |
SG (1) | SG150500A1 (es) |
SI (2) | SI1711502T1 (es) |
TN (1) | TNSN06248A1 (es) |
UA (2) | UA88646C2 (es) |
WO (1) | WO2005077957A2 (es) |
ZA (1) | ZA200606252B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0506607B8 (pt) | 2004-02-06 | 2021-05-25 | Euro Celtique Sa | métodos para produzir morfinonas protegidas por 3-o e carboxilatos de morfinona doenol protegidas por 3-o e composição |
JP2010504325A (ja) * | 2006-09-20 | 2010-02-12 | マリンクロット インコーポレイテッド | 置換モルフィナン−6−オン、並びにその塩および中間体の調製 |
EP2137189B1 (en) * | 2007-03-06 | 2015-05-06 | Mallinckrodt LLC | Process for the preparation of quaternary n-alkyl morphinan alkaloid salts |
US9040726B2 (en) | 2007-03-06 | 2015-05-26 | Mallinckrodt Llc | Process for the preparation of quaternary N-alkyl morphinan alkaloid salts |
NZ589496A (en) * | 2008-05-27 | 2013-02-22 | Mallinckrodt Llc | Processes and compounds for the preparation of normorphinans |
WO2010028004A2 (en) | 2008-09-03 | 2010-03-11 | Mallinckrodt Inc. | Substituted berbines and processes for their synthesis |
WO2011141490A1 (en) | 2010-05-10 | 2011-11-17 | Euro-Celtique S.A. | Combination of active loaded granules with additional actives |
SG184523A1 (en) | 2010-05-10 | 2012-11-29 | Euro Celtique Sa | Pharmaceutical compositions comprising hydromorphone and naloxone |
EP2568968B1 (en) | 2010-05-10 | 2017-07-12 | Euro-Celtique S.A. | Manufacturing of active-free granules and tablets comprising the same |
KR20160060768A (ko) | 2013-11-13 | 2016-05-30 | 유로-셀티큐 에스.에이. | 통증 및 오피오이드 장 기능장애 증후군의 치료를 위한 히드로모르폰 및 날록손 |
US10351512B2 (en) | 2015-09-30 | 2019-07-16 | Fujifilm Wako Pure Chemical Corporation | Method of producing organic compound |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2654756A (en) | 1949-10-20 | 1953-10-06 | Mallinckrodt Chemical Works | Process of preparing codeinone, dihydrocodeinone, and dihydromorphinone |
DE902257C (de) | 1951-07-17 | 1954-01-21 | Knoll Ag | Verfahren zur Herstellung von Acylderivaten der Enolform des Codeinons |
GB1495271A (en) | 1974-04-10 | 1977-12-14 | Macfarlan Smith Ltd | Dehydrohalogenation of codeinone derivatives |
US4472253A (en) | 1981-08-17 | 1984-09-18 | The Florida Board Of Regents On Behalf Of The Florida State University | Process for the preparation of an N-substituted 3-O-alkyl-14-hydroxynormorphinone derivative |
US5112975A (en) | 1984-03-27 | 1992-05-12 | Mallinckrodt Specialty Chemicals Company | Preparation of noroxymorphone from morphine |
SE9003665D0 (sv) | 1990-11-16 | 1990-11-16 | Kabivitrum Ab | Morphine prodrugs |
GB9116909D0 (en) | 1991-08-06 | 1991-09-18 | Salford Ultrafine Chem & Res | Morphine derivatives |
US5821374A (en) | 1995-11-21 | 1998-10-13 | Hoffmann-La Roche Inc. | Process for the oxidation of alcohols |
US5869669A (en) | 1996-07-26 | 1999-02-09 | Penick Corporation | Preparation of 14-hydroxynormorphinones from normorphinone dienol acylates |
GB9713703D0 (en) * | 1997-06-30 | 1997-09-03 | Johnson Matthey Plc | Preparation of opiates |
US6177567B1 (en) | 1999-10-15 | 2001-01-23 | Boehringer Ingelheim Chemicals, Inc. | Method for preparing oxycodone |
US6596877B2 (en) | 2001-10-17 | 2003-07-22 | Novartis Ag | Accelerated process for preparing O-methyl phenols, N-methyl heteroaromatic compounds, and methylated aminophenols |
BRPI0506607B8 (pt) | 2004-02-06 | 2021-05-25 | Euro Celtique Sa | métodos para produzir morfinonas protegidas por 3-o e carboxilatos de morfinona doenol protegidas por 3-o e composição |
-
2005
- 2005-02-04 BR BRPI0506607A patent/BRPI0506607B8/pt active IP Right Grant
- 2005-02-04 AU AU2005212258A patent/AU2005212258B2/en active Active
- 2005-02-04 PT PT05712726T patent/PT1711502E/pt unknown
- 2005-02-04 EP EP05712726A patent/EP1711502B1/en active Active
- 2005-02-04 ES ES05712726T patent/ES2313299T3/es active Active
- 2005-02-04 AP AP2006003716A patent/AP2006003716A0/xx unknown
- 2005-02-04 DK DK07014411.8T patent/DK1864987T3/da active
- 2005-02-04 RS RSP-2008/0553A patent/RS50663B/sr unknown
- 2005-02-04 KR KR1020077025207A patent/KR20070108956A/ko not_active Application Discontinuation
- 2005-02-04 NZ NZ548786A patent/NZ548786A/en unknown
- 2005-02-04 KR KR1020097016500A patent/KR101011460B1/ko active IP Right Grant
- 2005-02-04 AT AT05712726T patent/ATE406372T1/de active
- 2005-02-04 CA CA2808199A patent/CA2808199C/en active Active
- 2005-02-04 PL PL05712726T patent/PL1711502T3/pl unknown
- 2005-02-04 EP EP09015220A patent/EP2194059A3/en not_active Withdrawn
- 2005-02-04 PL PL07014411T patent/PL1864987T3/pl unknown
- 2005-02-04 SI SI200530468T patent/SI1711502T1/sl unknown
- 2005-02-04 UA UAA200704105A patent/UA88646C2/uk unknown
- 2005-02-04 EP EP07014411A patent/EP1864987B1/en active Active
- 2005-02-04 AT AT07014411T patent/ATE451374T1/de active
- 2005-02-04 WO PCT/US2005/003390 patent/WO2005077957A2/en active Application Filing
- 2005-02-04 EA EA200601394A patent/EA012905B1/ru not_active IP Right Cessation
- 2005-02-04 RS RSP-2010/0064A patent/RS51317B/sr unknown
- 2005-02-04 SI SI200530925T patent/SI1864987T1/sl unknown
- 2005-02-04 NZ NZ565355A patent/NZ565355A/en unknown
- 2005-02-04 DE DE602005018265T patent/DE602005018265D1/de active Active
- 2005-02-04 MX MXPA06008931A patent/MXPA06008931A/es active IP Right Grant
- 2005-02-04 DE DE602005009321T patent/DE602005009321D1/de active Active
- 2005-02-04 ES ES07014411T patent/ES2338054T3/es active Active
- 2005-02-04 SG SG200900838-4A patent/SG150500A1/en unknown
- 2005-02-04 EA EA200801811A patent/EA016062B1/ru not_active IP Right Cessation
- 2005-02-04 PT PT07014411T patent/PT1864987E/pt unknown
- 2005-02-04 CA CA2555215A patent/CA2555215C/en active Active
- 2005-02-04 DK DK05712726T patent/DK1711502T3/da active
- 2005-02-04 GE GEAP20059608A patent/GEP20084454B/en unknown
- 2005-02-04 KR KR1020077025206A patent/KR100921695B1/ko active IP Right Grant
- 2005-02-04 CN CN2005800040830A patent/CN1918168B/zh active Active
- 2005-02-04 JP JP2006552236A patent/JP4963968B2/ja active Active
- 2005-02-04 US US10/588,637 patent/US8003793B2/en active Active
- 2005-04-02 UA UAA200609622A patent/UA87833C2/uk unknown
-
2006
- 2006-07-28 ZA ZA200606252A patent/ZA200606252B/en unknown
- 2006-08-03 IL IL177281A patent/IL177281A/en active IP Right Grant
- 2006-08-04 TN TNP2006000248A patent/TNSN06248A1/fr unknown
- 2006-08-04 MA MA29240A patent/MA28346A1/fr unknown
- 2006-09-01 CR CR8590A patent/CR8590A/es unknown
- 2006-09-05 KR KR1020067018113A patent/KR100921696B1/ko active IP Right Grant
- 2006-09-05 EC EC2006006824A patent/ECSP066824A/es unknown
- 2006-09-06 NO NO20063989A patent/NO20063989L/no not_active Application Discontinuation
-
2007
- 2007-04-18 HK HK08106459.3A patent/HK1119160A1/xx unknown
- 2007-04-18 HK HK07104100.2A patent/HK1103071A1/xx unknown
-
2008
- 2008-11-12 CY CY20081101295T patent/CY1108506T1/el unknown
- 2008-11-26 HR HR20080618T patent/HRP20080618T3/xx unknown
-
2010
- 2010-02-25 CY CY20101100178T patent/CY1109838T1/el unknown
- 2010-03-05 HR HR20100123T patent/HRP20100123T1/hr unknown
- 2010-05-06 IL IL205596A patent/IL205596A/en active IP Right Grant
-
2011
- 2011-07-22 US US13/189,228 patent/US8198444B2/en active Active
-
2012
- 2012-05-15 US US13/472,227 patent/US8685996B2/en active Active
-
2014
- 2014-02-24 US US14/188,430 patent/US8975257B2/en active Active
-
2015
- 2015-03-02 NO NO20150276A patent/NO339083B1/no unknown
- 2015-03-03 US US14/637,129 patent/US9670218B2/en not_active Expired - Fee Related
-
2017
- 2017-05-04 US US15/587,118 patent/US20170233400A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CR8590A (es) | Metodos para elaborar morfinotas 3-0 protegidas carboxilatos de dienol, morfinota 3-0 protegidos | |
CY1118332T1 (el) | Μεθοδοι παραγωγης κυκλοαλκυλκαρβοξamιδο-πυριδιno βενζοϊκων οξεων | |
UY33981A (es) | ?método para preparar compuestos macrocíclicos inhibidores de serina proteasas de hepatitis c?. | |
CR11618A (es) | Inhibidores macrocíclicos de serina proteasa | |
BRPI0615705A2 (pt) | processo para preparar um composto, e, composto | |
WO2008110314A8 (de) | Fluoralkylphenylamidine und deren verwendung als fungizide | |
UY29479A1 (es) | Inhibidores de adn-pk | |
CY1112722T1 (el) | Μυκητοκτονες συνθεσεις | |
CR11241A (es) | Compuestos de pirazol y su uso como inhibidores de raf | |
ATE479687T1 (de) | Kinaseinhibitoren | |
CL2012000887A1 (es) | Mezcla fungicida sinergica que comprende fluorocitosina y otros compuestos fungicos; composicion fungicida que comprende dicha mezcla y un adyuvante agricolamente aceptable o portador. | |
ATE427965T1 (de) | Antikírper gegen 25-hydroxyvitamin d | |
CL2008003790A1 (es) | Metodo para purificar anticuerpo cd20 de una mezcla que comprende cristalizar el anticuerpo cd20 y recuperar el anticuerpo cd20 de la mezcla. | |
CR10156A (es) | Metodos para preparar alcoholes sulfonamida sustituidos e intermediarios de estos | |
ECSP11011494A (es) | Preparación de solido | |
GT200800251A (es) | Nitrilos espirociclicos como inhibidores de proteasa | |
CL2008001693A1 (es) | Compuestos derivados de piridil-pirimidinil-amino; composicion fungicida que comprende a dichos compuestos; y metodo para controlar los hongos fitopatogenos de los cultivos; y compuesto intermediario. | |
TW200732295A (en) | Selective N-sulfonylation of 2-amino trifluoroalkyl substituted alcohols | |
UY32424A (es) | Comprimidos conteniendo elivitegravir para tratamiento de infecciones virales | |
BRPI0514584A (pt) | método para preparar irbesartan e intermediários do mesmo | |
CR20120117A (es) | Métodos para la propagación vegetativa de gramíneas | |
CY1112746T1 (el) | Κρυοσυντηρηση ηπατοκυτταρων | |
GT200600102A (es) | Procedimiento para la preparacion de compuestos benzoxazol sustituidos | |
DE602006014001D1 (de) | Herstellung von 2-aminothiazol-5-carbonsäurederivaten | |
EA201400655A1 (ru) | Микробицидная композиция |