CR6451A - Acidos oxamicos y derivados como ligandos de receptores tiroideos - Google Patents

Acidos oxamicos y derivados como ligandos de receptores tiroideos

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Publication number
CR6451A
CR6451A CR6451A CR6451A CR6451A CR 6451 A CR6451 A CR 6451A CR 6451 A CR6451 A CR 6451A CR 6451 A CR6451 A CR 6451A CR 6451 A CR6451 A CR 6451A
Authority
CR
Costa Rica
Prior art keywords
derivatives
legands
oxamic acids
thyroid
thyroid receptors
Prior art date
Application number
CR6451A
Other languages
English (en)
Inventor
Ching Phoebe Chiang Yuan
Lee Dow Robert
Original Assignee
Abr Llc
Acumer Investigacion Desarrollo S L
Antonio Jose De Jesus De San Juan Bosco Echevarria Parres
Dystar Textilfarben Gmbh Y Co Deutschland Kg
Eco Flora S A
John Larry Sanders
Ranka Seema Ajay
Sanofi Aventis
Smithjkline Beecham Corp
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abr Llc, Acumer Investigacion Desarrollo S L, Antonio Jose De Jesus De San Juan Bosco Echevarria Parres, Dystar Textilfarben Gmbh Y Co Deutschland Kg, Eco Flora S A, John Larry Sanders, Ranka Seema Ajay, Sanofi Aventis, Smithjkline Beecham Corp, Pfizer Prod Inc filed Critical Abr Llc
Publication of CR6451A publication Critical patent/CR6451A/es

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    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
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    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
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    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
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  • Indole Compounds (AREA)

Abstract

Se refiere a nuevos ligandos de receptores de tiroideos, más particularmente a nuevos ácidos oxámicos y sus derivados, que son útiles en el tratamiento de la obesidad, hiperlipidemia, glaucoma, arritmia cardíaca, trastornos de la piel, enfermedades de tiroides, hipotiroidismo, y trastornos y enfermedades como diabetes mellitus, aterosclerosis, hipertensión, enfermedad cardíaca coronaria, hipercolesterolemia, depresión y osteoporosis.
CR6451A 1999-03-01 2001-08-30 Acidos oxamicos y derivados como ligandos de receptores tiroideos CR6451A (es)

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AU772282B2 (en) 2004-04-22
US6545018B2 (en) 2003-04-08
WO2000051971A1 (en) 2000-09-08
CA2363145A1 (en) 2000-09-08
ID29889A (id) 2001-10-18
TR200102561T2 (tr) 2002-02-21
JP3699355B2 (ja) 2005-09-28
EA200100841A1 (ru) 2002-02-28
UY26043A1 (es) 2000-09-29
US20020049226A1 (en) 2002-04-25
BG105954A (en) 2002-06-28
CA2363145C (en) 2006-02-14
GT200000025AA (es) 2001-08-22
EP1157001A1 (en) 2001-11-28
ATE272609T1 (de) 2004-08-15
CZ20013117A3 (cs) 2002-06-12
IL144765A0 (en) 2002-06-30
ES2223454T3 (es) 2005-03-01
HUP0200248A3 (en) 2002-11-28
EP1157001B1 (en) 2004-08-04
HN2000000029A (es) 2001-02-02
PA8491501A1 (es) 2001-04-30
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