CR20140124A - Metabolitos de transclomifeno y usos de los mismos - Google Patents

Metabolitos de transclomifeno y usos de los mismos

Info

Publication number
CR20140124A
CR20140124A CR20140124A CR20140124A CR20140124A CR 20140124 A CR20140124 A CR 20140124A CR 20140124 A CR20140124 A CR 20140124A CR 20140124 A CR20140124 A CR 20140124A CR 20140124 A CR20140124 A CR 20140124A
Authority
CR
Costa Rica
Prior art keywords
metabolites
transclomifen
same
relates
present
Prior art date
Application number
CR20140124A
Other languages
English (en)
Spanish (es)
Inventor
Joseph S Podolski
Ronald D Wiehle
Original Assignee
Repros Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46724628&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR20140124(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Repros Therapeutics Inc filed Critical Repros Therapeutics Inc
Publication of CR20140124A publication Critical patent/CR20140124A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Emergency Medicine (AREA)
  • Pregnancy & Childbirth (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CR20140124A 2011-08-04 2014-03-13 Metabolitos de transclomifeno y usos de los mismos CR20140124A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161515278P 2011-08-04 2011-08-04

Publications (1)

Publication Number Publication Date
CR20140124A true CR20140124A (es) 2014-05-13

Family

ID=46724628

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20140124A CR20140124A (es) 2011-08-04 2014-03-13 Metabolitos de transclomifeno y usos de los mismos

Country Status (21)

Country Link
US (1) US9981906B2 (OSRAM)
EP (2) EP3351527A1 (OSRAM)
JP (2) JP6433785B2 (OSRAM)
KR (1) KR20140054110A (OSRAM)
CN (1) CN103702975B (OSRAM)
AU (2) AU2012289964B2 (OSRAM)
BR (1) BR112014000908A2 (OSRAM)
CA (1) CA2841572C (OSRAM)
CL (1) CL2014000268A1 (OSRAM)
CO (1) CO6862154A2 (OSRAM)
CR (1) CR20140124A (OSRAM)
EA (1) EA201490416A1 (OSRAM)
IL (1) IL230287B (OSRAM)
MX (1) MX355316B (OSRAM)
MY (2) MY170718A (OSRAM)
NI (1) NI201400008A (OSRAM)
PH (1) PH12014500144A1 (OSRAM)
SG (1) SG10201606425WA (OSRAM)
UA (1) UA113291C2 (OSRAM)
WO (1) WO2013020017A1 (OSRAM)
ZA (1) ZA201400406B (OSRAM)

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BR112014029131B1 (pt) 2012-05-31 2021-03-09 Allergan Pharmaceuticals International Limited cápsula de mucoadesivo
HK1211852A1 (en) 2012-11-02 2016-06-03 Repros Therapeutics Inc. Methods and compositions for treating progesterone-dependent conditions
EP2914294A1 (en) 2012-11-02 2015-09-09 Repros Therapeutics Inc. Trans-clomiphene for use in cancer therapy
US20190008804A1 (en) * 2016-01-12 2019-01-10 Repros Therapeutics Inc. Trans-Clomiphene and Progesterone Receptor Antagonist Combination Therapy for Treating Hormone-Dependent Conditions
US20190054044A1 (en) * 2016-02-25 2019-02-21 Aspen Park Pharmaceuticals, Inc. Oral dosage form of both clomiphene isomers and method of using same to treat secondary hypogonadism and minimize drug side effects in men
EP3368506B1 (en) 2016-04-22 2023-09-06 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Process for the preparation of enclomiphene citrate having needle shaped crystal habit.

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Also Published As

Publication number Publication date
JP2014529584A (ja) 2014-11-13
PH12014500144A1 (en) 2014-02-24
NZ621892A (en) 2016-03-31
AU2012289964A1 (en) 2014-01-30
US20140163114A1 (en) 2014-06-12
CN103702975B (zh) 2016-03-16
MX2014000825A (es) 2014-02-27
CO6862154A2 (es) 2014-02-10
IL230287A0 (en) 2014-03-06
MX355316B (es) 2018-04-16
MY191802A (en) 2022-07-15
BR112014000908A2 (pt) 2017-02-21
JP6433785B2 (ja) 2018-12-05
CL2014000268A1 (es) 2014-11-14
IL230287B (en) 2019-07-31
WO2013020017A1 (en) 2013-02-07
NI201400008A (es) 2015-12-10
US9981906B2 (en) 2018-05-29
UA113291C2 (xx) 2017-01-10
MY170718A (en) 2019-08-27
EP3351527A1 (en) 2018-07-25
EP2744777A1 (en) 2014-06-25
CA2841572A1 (en) 2013-02-07
AU2017204171A1 (en) 2017-07-13
AU2012289964B2 (en) 2017-03-23
KR20140054110A (ko) 2014-05-08
HK1196349A1 (zh) 2014-12-12
JP2019023210A (ja) 2019-02-14
SG10201606425WA (en) 2016-09-29
ZA201400406B (en) 2014-11-26
CN103702975A (zh) 2014-04-02
EA201490416A1 (ru) 2014-11-28
CA2841572C (en) 2020-10-13

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