CR20130069A - Quelatos de oligonucleótidos - Google Patents

Quelatos de oligonucleótidos

Info

Publication number
CR20130069A
CR20130069A CR20130069A CR20130069A CR20130069A CR 20130069 A CR20130069 A CR 20130069A CR 20130069 A CR20130069 A CR 20130069A CR 20130069 A CR20130069 A CR 20130069A CR 20130069 A CR20130069 A CR 20130069A
Authority
CR
Costa Rica
Prior art keywords
cheats
oligonucleotide
oligonucleotide cheats
Prior art date
Application number
CR20130069A
Other languages
English (en)
Spanish (es)
Inventor
Andrew Vaillant
Michel Bazinet
Original Assignee
Replicor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45594559&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR20130069(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Replicor Inc filed Critical Replicor Inc
Publication of CR20130069A publication Critical patent/CR20130069A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/04—Chelating agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
CR20130069A 2010-08-20 2013-02-19 Quelatos de oligonucleótidos CR20130069A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37525710P 2010-08-20 2010-08-20

Publications (1)

Publication Number Publication Date
CR20130069A true CR20130069A (es) 2013-09-20

Family

ID=45594559

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20130069A CR20130069A (es) 2010-08-20 2013-02-19 Quelatos de oligonucleótidos

Country Status (35)

Country Link
US (2) US8513211B2 (cg-RX-API-DMAC10.html)
EP (1) EP2605794B1 (cg-RX-API-DMAC10.html)
JP (1) JP5775581B2 (cg-RX-API-DMAC10.html)
KR (3) KR20150039873A (cg-RX-API-DMAC10.html)
CN (2) CN103768086B (cg-RX-API-DMAC10.html)
AU (1) AU2011291401B2 (cg-RX-API-DMAC10.html)
BR (1) BR112013003875B1 (cg-RX-API-DMAC10.html)
CA (2) CA2855690C (cg-RX-API-DMAC10.html)
CL (1) CL2013000445A1 (cg-RX-API-DMAC10.html)
CO (1) CO6670525A2 (cg-RX-API-DMAC10.html)
CR (1) CR20130069A (cg-RX-API-DMAC10.html)
CU (1) CU20130022A7 (cg-RX-API-DMAC10.html)
CY (1) CY1118207T1 (cg-RX-API-DMAC10.html)
DK (1) DK2605794T3 (cg-RX-API-DMAC10.html)
DO (1) DOP2013000041A (cg-RX-API-DMAC10.html)
EA (1) EA026660B1 (cg-RX-API-DMAC10.html)
EC (1) ECSP13012449A (cg-RX-API-DMAC10.html)
ES (1) ES2598556T3 (cg-RX-API-DMAC10.html)
GT (1) GT201300040A (cg-RX-API-DMAC10.html)
HR (1) HRP20161333T1 (cg-RX-API-DMAC10.html)
HU (1) HUE029521T2 (cg-RX-API-DMAC10.html)
IL (1) IL224237A (cg-RX-API-DMAC10.html)
LT (1) LT2605794T (cg-RX-API-DMAC10.html)
MX (1) MX340294B (cg-RX-API-DMAC10.html)
MY (1) MY160961A (cg-RX-API-DMAC10.html)
NZ (1) NZ606364A (cg-RX-API-DMAC10.html)
PH (1) PH12013500192B1 (cg-RX-API-DMAC10.html)
PL (1) PL2605794T3 (cg-RX-API-DMAC10.html)
PT (1) PT2605794T (cg-RX-API-DMAC10.html)
RS (1) RS55245B1 (cg-RX-API-DMAC10.html)
SG (1) SG187165A1 (cg-RX-API-DMAC10.html)
SI (1) SI2605794T1 (cg-RX-API-DMAC10.html)
SM (1) SMT201600370B (cg-RX-API-DMAC10.html)
WO (1) WO2012021985A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201300497B (cg-RX-API-DMAC10.html)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6047270B2 (ja) 2006-08-11 2016-12-21 バイオマリン テクノロジーズ ベー.フェー. Dnaリピートの不安定性に関連した遺伝的障害を治療するための方法及び手段
JP5646320B2 (ja) 2007-05-11 2014-12-24 アダイニクス, インコーポレイテッド 遺伝子発現と疼痛
NZ584793A (en) 2007-10-26 2012-05-25 Academisch Ziekenhuis Leiden Means and methods for counteracting muscle disorders
EP2119783A1 (en) 2008-05-14 2009-11-18 Prosensa Technologies B.V. Method for efficient exon (44) skipping in Duchenne Muscular Dystrophy and associated means
CA2862628C (en) 2012-01-27 2021-08-24 Prosensa Technologies B.V. Rna modulating oligonucleotides with improved characteristics for the treatment of duchenne and becker muscular dystrophy
PT2841578T (pt) 2012-04-23 2017-08-10 Biomarin Tech Bv Resumo
RU2668136C2 (ru) * 2012-05-10 2018-09-26 Эйдинкс, Инк. Композиции для доставки активных ингредиентов
HUE054875T2 (hu) * 2012-05-18 2021-10-28 Replicor Inc Oligonukleotid kelátkomplex-polipeptid készítmények és eljárások
AR091065A1 (es) * 2012-05-18 2014-12-30 Replicor Inc Una formulacion farmaceutica que comprende un quelato de oligonucleotidos antiviral para el tratamiento de una infeccion antiviral
CN104603271B (zh) * 2012-07-03 2019-07-19 马林生物科技有限公司 用于治疗肌肉萎缩症患者的寡核苷酸
CN104837501B (zh) 2012-08-30 2018-11-02 里普利科股份有限公司 治疗乙型肝炎及丁型肝炎感染的方法
KR20170029577A (ko) 2014-07-10 2017-03-15 레플리코르 인코포레이티드 B형 간염 및 d형 간염 바이러스 감염의 치료 방법
CN106661578B (zh) 2014-08-15 2020-08-04 埃迪恩克斯股份有限公司 用于疼痛治疗的寡核苷酸诱饵
WO2016030863A1 (en) 2014-08-29 2016-03-03 Glaxosmithkline Intellectual Property Development Limited Compounds and methods for treating viral infections
JP2018513127A (ja) 2015-04-23 2018-05-24 ジェロン・コーポレーションGeron Corporation 多価カチオン塩組成物を用いたポリヌクレオチド調製方法
US11166976B2 (en) 2018-11-08 2021-11-09 Aligos Therapeutics, Inc. S-antigen transport inhibiting oligonucleotide polymers and methods
US20200147124A1 (en) * 2018-11-08 2020-05-14 Aligos Therapeutics, Inc. S-antigen transport inhibiting oligonucleotide polymers and methods
US20230250125A1 (en) 2020-04-01 2023-08-10 Janssen Biopharma, Inc. Nucleic acid polymers
WO2022109129A1 (en) * 2020-11-20 2022-05-27 Aligos Therapeutics, Inc. Conjugates of s-antigen transport inhibiting oligonucleotide polymers having enhanced liver targeting
TW202245809A (zh) 2020-12-18 2022-12-01 美商詹森藥物公司 用於治療b型肝炎病毒感染之組合療法
WO2022152869A1 (en) 2021-01-15 2022-07-21 Janssen Sciences Ireland Unlimited Company Use of oligonucleotides for individuals with hepatic impairment
JP2024521897A (ja) * 2021-06-02 2024-06-04 アタランタ セラピューティクス,インコーポレーテッド 治療用オリゴヌクレオチドを中枢神経系に送達するための組成物及び方法
CN117616121A (zh) 2021-07-09 2024-02-27 葛兰素史密斯克莱知识产权(第3号)有限公司 寡核苷酸用于具有肾脏损伤的个体的用途
EP4728073A1 (en) * 2023-06-16 2026-04-22 Ractigen Therapeutics Oligonucleotide formulation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2300938A1 (en) * 1997-08-20 1999-02-25 Somagenics, Inc. Antisense and antigene therapeutics with improved binding properties and methods for their use
JP3667047B2 (ja) * 1997-09-12 2005-07-06 キヤノン株式会社 人工核酸およびその製造方法、デオキシリボフラノース化合物、リボフラノース化合物およびこれらの製造方法
US6653467B1 (en) * 2000-04-26 2003-11-25 Jcr Pharmaceutical Co., Ltd. Medicament for treatment of Duchenne muscular dystrophy
JP4836366B2 (ja) * 2000-08-25 2011-12-14 雅文 松尾 デュシェンヌ型筋ジストロフィー治療剤
WO2005023829A1 (ja) * 2003-09-02 2005-03-17 Japan Science And Technology Agency 金属錯体型核酸
WO2005026188A1 (ja) * 2003-09-08 2005-03-24 Japan Science And Technology Agency 金属錯体型核酸
WO2007005626A1 (en) * 2005-07-01 2007-01-11 Bioveris Corporation Compositions and methods for detecting, amplifying, and/or isolating nucleic acids
WO2009065181A1 (en) * 2007-11-21 2009-05-28 Apollo Life Sciences Limited Nanostructures suitable for delivery of agents

Also Published As

Publication number Publication date
MX2013001668A (es) 2013-07-22
HUE029521T2 (en) 2017-03-28
KR101606495B1 (ko) 2016-03-28
JP2013536195A (ja) 2013-09-19
CL2013000445A1 (es) 2013-11-22
ES2598556T3 (es) 2017-01-27
CA2806616A1 (en) 2012-02-23
JP5775581B2 (ja) 2015-09-09
ZA201300497B (en) 2013-09-25
EA201300259A1 (ru) 2013-12-30
US8513211B2 (en) 2013-08-20
EA026660B1 (ru) 2017-05-31
SMT201600370B (it) 2016-11-10
BR112013003875B1 (pt) 2021-10-05
US8716259B2 (en) 2014-05-06
AU2011291401A1 (en) 2013-01-10
HRP20161333T1 (hr) 2016-12-02
CN103052405A (zh) 2013-04-17
EP2605794B1 (en) 2016-07-20
RS55245B1 (sr) 2017-02-28
IL224237A (en) 2015-09-24
PL2605794T3 (pl) 2017-01-31
KR20150082685A (ko) 2015-07-15
US20130296410A1 (en) 2013-11-07
KR20150039873A (ko) 2015-04-13
US20120046348A1 (en) 2012-02-23
SG187165A1 (en) 2013-02-28
HK1184058A1 (zh) 2014-01-17
PH12013500192B1 (en) 2018-11-23
MX340294B (es) 2016-07-04
CU20130022A7 (es) 2013-04-19
MY160961A (en) 2017-03-31
CA2855690A1 (en) 2012-02-23
KR20130099067A (ko) 2013-09-05
CA2855690C (en) 2015-08-25
PH12013500192A1 (cg-RX-API-DMAC10.html) 2013-03-11
AU2011291401B2 (en) 2014-11-27
WO2012021985A1 (en) 2012-02-23
CA2806616C (en) 2015-08-11
ECSP13012449A (es) 2013-04-30
LT2605794T (lt) 2016-10-25
GT201300040A (es) 2014-09-02
HK1198123A1 (en) 2015-03-13
CN103052405B (zh) 2015-11-25
PT2605794T (pt) 2016-10-25
DOP2013000041A (es) 2017-12-15
NZ606364A (en) 2014-12-24
DK2605794T3 (en) 2016-10-24
EP2605794A4 (en) 2014-07-02
CO6670525A2 (es) 2013-05-15
BR112013003875A2 (en) 2018-03-13
CY1118207T1 (el) 2017-06-28
CN103768086A (zh) 2014-05-07
EP2605794A1 (en) 2013-06-26
SI2605794T1 (sl) 2017-01-31
CN103768086B (zh) 2015-10-14

Similar Documents

Publication Publication Date Title
BR112013012195A2 (pt) oligonucleotídeo imunoestimulatórios
IL221029B (en) Targeted genomic alteration
BR112012028556A2 (pt) Indóis
DE102011100241A8 (de) Nitridhalbleiterbauteil
CR20130111A (es) Triazina-oxidiazoles
DE10170954T8 (de) Mikrowellendruckgarer
EP2609148A4 (en) PHTHALIC ACID-FREE SOFT MAKER
EP2575450A4 (en) CYCLOPROPENZUSAMMENSETZUNGEN
PT2641343T (pt) Configuração de subtrama
UA21334S (uk) Цукерка
DE112011102774A5 (de) Antriebsstrang
BR112013014392A2 (pt) compostos cetolídeos
DOS2010000249S (es) Confiteria
DE102011117046A8 (de) Doppelkupplungswindungsgetriebe
DE112011101226A5 (de) Linearwegmesssystem
DK2635269T3 (da) Kombinationspræparat
DE102010038420A8 (de) Reinigungungsvorrichtung
DE102011002623A8 (de) Ventilsteuerzeitversteller
DE112011103919A5 (de) Endoskop
DE102010035554B8 (de) Fußtüröffner
DE102010019119B8 (de) Cuttermesser
DE112010005518A5 (de) Dichtungsmanchette
CO6801789A2 (es) N-hetarilmetil pirazolilcarboxamidas
EP2556786A4 (en) Endoscope
BRPI1014370A2 (pt) parasiticida