CO6382142A2 - Combinación farmaceutica de 3-(3-dimetilamino-1-etil-2-metil-propil)-fenol y un anti-epileptico. - Google Patents

Combinación farmaceutica de 3-(3-dimetilamino-1-etil-2-metil-propil)-fenol y un anti-epileptico.

Info

Publication number
CO6382142A2
CO6382142A2 CO11018461A CO11018461A CO6382142A2 CO 6382142 A2 CO6382142 A2 CO 6382142A2 CO 11018461 A CO11018461 A CO 11018461A CO 11018461 A CO11018461 A CO 11018461A CO 6382142 A2 CO6382142 A2 CO 6382142A2
Authority
CO
Colombia
Prior art keywords
methyl
component
phenol
propil
etil
Prior art date
Application number
CO11018461A
Other languages
English (en)
Spanish (es)
Inventor
Petra Bloms-Fluke
Klaus Schiene
Thomas Christoph
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40345058&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO6382142(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of CO6382142A2 publication Critical patent/CO6382142A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
CO11018461A 2008-09-05 2011-02-16 Combinación farmaceutica de 3-(3-dimetilamino-1-etil-2-metil-propil)-fenol y un anti-epileptico. CO6382142A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08015625 2008-09-05

Publications (1)

Publication Number Publication Date
CO6382142A2 true CO6382142A2 (es) 2012-02-15

Family

ID=40345058

Family Applications (1)

Application Number Title Priority Date Filing Date
CO11018461A CO6382142A2 (es) 2008-09-05 2011-02-16 Combinación farmaceutica de 3-(3-dimetilamino-1-etil-2-metil-propil)-fenol y un anti-epileptico.

Country Status (28)

Country Link
US (1) US20100063148A1 (OSRAM)
EP (2) EP2735338B1 (OSRAM)
JP (4) JP5731387B2 (OSRAM)
KR (3) KR101730924B1 (OSRAM)
CN (2) CN102159284B (OSRAM)
AR (2) AR073361A1 (OSRAM)
AU (3) AU2009289776A1 (OSRAM)
BR (1) BRPI0920521A2 (OSRAM)
CA (1) CA2735857C (OSRAM)
CL (1) CL2011000317A1 (OSRAM)
CO (1) CO6382142A2 (OSRAM)
CY (2) CY1115751T1 (OSRAM)
DK (2) DK2331210T3 (OSRAM)
EC (1) ECSP11010869A (OSRAM)
ES (2) ES2513394T3 (OSRAM)
HR (2) HRP20140663T1 (OSRAM)
HU (1) HUE043278T2 (OSRAM)
IL (3) IL211135A (OSRAM)
LT (1) LT2735338T (OSRAM)
MX (1) MX2011002339A (OSRAM)
PE (5) PE20190914A1 (OSRAM)
PL (2) PL2735338T3 (OSRAM)
PT (2) PT2331210E (OSRAM)
RU (2) RU2674150C1 (OSRAM)
SI (2) SI2331210T1 (OSRAM)
TR (1) TR201904388T4 (OSRAM)
WO (1) WO2010025931A2 (OSRAM)
ZA (1) ZA201101449B (OSRAM)

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US20090176882A1 (en) 2008-12-09 2009-07-09 Depomed, Inc. Gastric retentive gabapentin dosage forms and methods for using same
EP2462990B2 (en) 2006-06-15 2018-04-18 UCB Pharma GmbH Pharmaceutical composition comprising lacosamide and levetiracetam with synergistic anticonvulsant effect
RU2674150C1 (ru) * 2008-09-05 2018-12-05 Грюненталь Гмбх Фармацевтическая комбинация
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FR2943246B1 (fr) * 2009-03-19 2011-07-29 Biocodex Compose pour son utilisation dans le traitement des neuropathies peripheriques
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AU2011276170B2 (en) 2010-07-06 2016-03-10 Grunenthal Gmbh Novel gastro- retentive dosage forms comprising a GABA Analog and an opioid
RU2544552C2 (ru) 2010-07-30 2015-03-20 Торэй Индастриз, Инк. Терапевтическое средство или профилактическое средство для нейропатической боли
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US9855286B2 (en) 2012-05-18 2018-01-02 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-di methyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a salicylic acid component
US20130310385A1 (en) 2012-05-18 2013-11-21 Gruenenthal Gmbh Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine and Antidepressants
US20130310435A1 (en) 2012-05-18 2013-11-21 Gruenenthal Gmbh Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4,9' -dihydro-3'H-spiro[cyclohexane-1,1' -pyrano[3,4,b]indol]-4-amine and Paracetamol or Propacetamol
US9345689B2 (en) * 2012-05-18 2016-05-24 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N, N-dimethyl-4-phenyl-4,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and an anticonvulsant
US9308196B2 (en) * 2012-05-18 2016-04-12 Gruenenthal Gmbh Pharmaceutical composition comprising (1 r,4r) -6'-fluoro-N ,N-dimethyl-4-phenyl-4',9'-d ihydro-3'H-spiro[cyclohexane-1,1'-pyrano-[3,4,b]indol]-4-amine and an oxicam
KR20150075408A (ko) * 2012-11-01 2015-07-03 토렌트 파마슈티칼스 리미티드 비경구용 타펜타돌의 약학 조성물
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US9549909B2 (en) 2013-05-03 2017-01-24 The Katholieke Universiteit Leuven Method for the treatment of dravet syndrome
CN103655523A (zh) * 2013-12-24 2014-03-26 南京艾德凯腾生物医药有限责任公司 他喷他多组合物
WO2017112701A1 (en) 2015-12-22 2017-06-29 Zogenix International Limited Metabolism resistant fenfluramine analogs and methods of using the same
HRP20250898T1 (hr) 2015-12-22 2025-09-26 Zogenix International Limited Pripravci fenfluramina i postupci njihove pripreme
JP2019526544A (ja) 2016-08-24 2019-09-19 ゾゲニクス インターナショナル リミテッド ５−ｈｔ２ｂアゴニストの形成を阻害するための製剤およびその使用方法
US10682317B2 (en) 2017-09-26 2020-06-16 Zogenix International Limited Ketogenic diet compatible fenfluramine formulation
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Also Published As

Publication number Publication date
CN102159284B (zh) 2015-12-09
CL2011000317A1 (es) 2011-06-17
KR20160086981A (ko) 2016-07-20
HRP20190500T1 (hr) 2019-08-09
DK2331210T3 (da) 2014-08-11
AU2009289776A1 (en) 2010-03-11
JP2015096530A (ja) 2015-05-21
JP2012501986A (ja) 2012-01-26
AR117613A2 (es) 2021-08-18
WO2010025931A2 (en) 2010-03-11
AU2018202879A1 (en) 2018-05-17
HRP20140663T1 (hr) 2014-10-10
PE20142371A1 (es) 2015-02-04
MX2011002339A (es) 2011-04-04
EP2735338A1 (en) 2014-05-28
ECSP11010869A (es) 2011-04-29
HUE043278T2 (hu) 2019-08-28
JP2017071636A (ja) 2017-04-13
RU2674150C1 (ru) 2018-12-05
JP5731387B2 (ja) 2015-06-10
CN105520924A (zh) 2016-04-27
SI2331210T1 (sl) 2014-10-30
CN102159284A (zh) 2011-08-17
KR20170048602A (ko) 2017-05-08
PE20190914A1 (es) 2019-06-26
KR101641519B1 (ko) 2016-07-21
US20100063148A1 (en) 2010-03-11
PL2735338T3 (pl) 2019-07-31
KR20110057144A (ko) 2011-05-31
KR101730924B1 (ko) 2017-04-27
PT2735338T (pt) 2019-05-24
RU2571501C2 (ru) 2015-12-20
CY1115751T1 (el) 2017-01-25
PL2331210T3 (pl) 2014-12-31
IL237392B (en) 2019-08-29
AU2016203053A1 (en) 2016-06-02
KR101851120B1 (ko) 2018-04-23
LT2735338T (lt) 2019-04-10
TR201904388T4 (tr) 2019-05-21
PE20142372A1 (es) 2015-02-04
PT2331210E (pt) 2014-08-25
IL237391A (en) 2017-12-31
SI2735338T1 (sl) 2019-04-30
ZA201101449B (en) 2011-10-26
ES2513394T3 (es) 2014-10-27
CA2735857C (en) 2019-05-28
AU2018202879B2 (en) 2020-03-12
AU2016203053B2 (en) 2018-01-25
BRPI0920521A2 (pt) 2018-01-16
IL211135A (en) 2017-09-28
ES2719900T3 (es) 2019-07-16
HK1198145A1 (en) 2015-03-13
HK1159011A1 (en) 2012-07-27
WO2010025931A3 (en) 2010-06-17
PE20142357A1 (es) 2015-02-04
EP2331210B1 (en) 2014-07-09
CA2735857A1 (en) 2010-03-11
PE20110291A1 (es) 2011-06-04
JP2019131578A (ja) 2019-08-08
AR073361A1 (es) 2010-11-03
RU2011112444A (ru) 2012-10-10
DK2735338T3 (en) 2019-04-23
EP2331210A2 (en) 2011-06-15
IL237391A0 (en) 2015-04-30
IL237392A0 (en) 2015-04-30
IL211135A0 (en) 2011-04-28
EP2735338B1 (en) 2019-02-06
CN105520924B (zh) 2019-04-09
CY1121492T1 (el) 2020-05-29

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