CO6341476A2 - Derivados de piridino-piridinonas, su preparacion y su aplicacion en terapeutica - Google Patents

Derivados de piridino-piridinonas, su preparacion y su aplicacion en terapeutica

Info

Publication number
CO6341476A2
CO6341476A2 CO11001537A CO11001537A CO6341476A2 CO 6341476 A2 CO6341476 A2 CO 6341476A2 CO 11001537 A CO11001537 A CO 11001537A CO 11001537 A CO11001537 A CO 11001537A CO 6341476 A2 CO6341476 A2 CO 6341476A2
Authority
CO
Colombia
Prior art keywords
therapeutics
preparation
application
derivatives
piridinonas
Prior art date
Application number
CO11001537A
Other languages
English (en)
Inventor
Patrice Bellevergue
Gilbert Lassalle
Challier Cecile Volle
Pierre Savi
Valerie Martin
Gary Mccort
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of CO6341476A2 publication Critical patent/CO6341476A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

La invención se refiere a os derivados de piridino-piridinonas, de fórmula general (D: en la que R1, R2, R3, R4, R5, R6, R7, V, W, Y, Z, m son tales como se han definido en la descripción. Procedimiento de preparación y aplicación en terapéutica.
CO11001537A 2008-07-08 2011-01-07 Derivados de piridino-piridinonas, su preparacion y su aplicacion en terapeutica CO6341476A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0803862A FR2933700B1 (fr) 2008-07-08 2008-07-08 Derives de pyridino-pyridinones, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
CO6341476A2 true CO6341476A2 (es) 2011-11-21

Family

ID=40219672

Family Applications (1)

Application Number Title Priority Date Filing Date
CO11001537A CO6341476A2 (es) 2008-07-08 2011-01-07 Derivados de piridino-piridinonas, su preparacion y su aplicacion en terapeutica

Country Status (32)

Country Link
US (1) US8436011B2 (es)
EP (1) EP2315767B1 (es)
JP (1) JP5606434B2 (es)
KR (1) KR20110031372A (es)
CN (1) CN102149713B (es)
AR (1) AR072798A1 (es)
AU (1) AU2009267827B2 (es)
BR (1) BRPI0915438A2 (es)
CA (1) CA2729833A1 (es)
CL (1) CL2011000048A1 (es)
CO (1) CO6341476A2 (es)
CR (1) CR11866A (es)
DO (1) DOP2011000008A (es)
EA (1) EA019362B1 (es)
EC (1) ECSP11010742A (es)
ES (1) ES2438540T3 (es)
FR (1) FR2933700B1 (es)
HK (1) HK1159108A1 (es)
HN (1) HN2011000076A (es)
IL (1) IL210514A (es)
MA (1) MA32544B1 (es)
MX (1) MX2011000330A (es)
MY (1) MY149705A (es)
NI (1) NI201100011A (es)
NZ (1) NZ590862A (es)
PE (1) PE20110405A1 (es)
SV (1) SV2011003800A (es)
TW (1) TW201004955A (es)
UA (1) UA102858C2 (es)
UY (1) UY31971A (es)
WO (1) WO2010004197A2 (es)
ZA (1) ZA201100210B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0205455D0 (en) 2002-03-07 2002-04-24 Molecular Sensing Plc Nucleic acid probes, their synthesis and use
FR2933700B1 (fr) 2008-07-08 2010-07-30 Sanofi Aventis Derives de pyridino-pyridinones, leur preparation et leur application en therapeutique
FR2952934B1 (fr) * 2009-11-23 2012-06-22 Sanofi Aventis Derives de pyridino-pyridinones, leur preparation et leur application en therapeutique
FR2954943B1 (fr) * 2010-01-07 2013-03-01 Sanofi Aventis Derives de pyridino-pyridinones arylsulfonamides, leur preparation et leur application en therapeutique
FR2955109B1 (fr) * 2010-01-08 2012-09-07 Sanofi Aventis Derives de 5-oxo-5,8-dihydro-pyrido[2, 3-d]pyrimidine, leur preparation et leur application en therapeutique
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US8628554B2 (en) 2010-06-13 2014-01-14 Virender K. Sharma Intragastric device for treating obesity
US10010439B2 (en) 2010-06-13 2018-07-03 Synerz Medical, Inc. Intragastric device for treating obesity
EP2524915A1 (en) 2011-05-20 2012-11-21 Sanofi 2-Amino-3-(imidazol-2-yl)-pyridin-4-one derivatives and their use as VEGF receptor kinase inhibitors
WO2014012942A1 (en) * 2012-07-17 2014-01-23 Sanofi Use of vegfr-3 inhibitors for treating hepatocellular carcinoma
UA110688C2 (uk) * 2012-09-21 2016-01-25 Пфайзер Інк. Біциклічні піридинони
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
JP2018052878A (ja) * 2016-09-29 2018-04-05 第一三共株式会社 ピリジン化合物
CN111344287B (zh) 2017-11-14 2023-12-19 默沙东有限责任公司 作为吲哚胺2，3-双加氧酶(ido)抑制剂的新型取代的联芳基化合物
US11498904B2 (en) 2017-11-14 2022-11-15 Merck Sharp & Dohme Llc Substituted biaryl compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors
KR20200104873A (ko) * 2017-12-06 2020-09-04 린 바이오사이언스, 피티와이 엘티디. 튜불린 억제제

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3845008A (en) * 1973-03-02 1974-10-29 Du Pont Brake lining composition comprising particulate tar residue
US4959363A (en) * 1989-06-23 1990-09-25 Sterling Drug Inc. Quinolonecarboxamide compounds, their preparation and use as antivirals.
EP0610231A1 (en) * 1992-09-09 1994-08-17 STACKPOLE Limited Powder metal alloy process
US5332422A (en) * 1993-07-06 1994-07-26 Ford Motor Company Solid lubricant and hardenable steel coating system
AU7811194A (en) * 1993-10-02 1995-05-01 Cerasiv Gmbh Molded article
US5518639A (en) * 1994-08-12 1996-05-21 Hoeganaes Corp. Powder metallurgy lubricant composition and methods for using same
US5641580A (en) * 1995-10-03 1997-06-24 Osram Sylvania Inc. Advanced Mo-based composite powders for thermal spray applications
JP3537286B2 (ja) * 1997-03-13 2004-06-14 株式会社三協精機製作所 焼結含油軸受およびそれを用いたモータ
CA2207579A1 (fr) * 1997-05-28 1998-11-28 Paul Caron Piece frittee a surface anti-abrasive et procede pour sa realisation
US6689424B1 (en) * 1999-05-28 2004-02-10 Inframat Corporation Solid lubricant coatings produced by thermal spray methods
EP1338679B1 (en) * 2000-11-16 2010-09-22 Honda Giken Kogyo Kabushiki Kaisha Metallic sliding member and method of surface-treating thereof
JP2004124130A (ja) * 2002-09-30 2004-04-22 Fujimi Inc 溶射用粉末及びその製造方法並びに該溶射用粉末を用いた溶射方法
US7300488B2 (en) * 2003-03-27 2007-11-27 Höganäs Ab Powder metal composition and method for producing components thereof
TW200502236A (en) * 2003-03-28 2005-01-16 Hoffmann La Roche Novel pyrido[2,3-d]pyrimidin-7-carboxylic acid derivatives, their manufacture and use as pharmaceutical agents
DE10326769B3 (de) * 2003-06-13 2004-11-11 Esk Ceramics Gmbh & Co. Kg Dauerhafte BN-Formtrennschichten für das Druckgießen von Nichteisenmetallen
US7563748B2 (en) 2003-06-23 2009-07-21 Cognis Ip Management Gmbh Alcohol alkoxylate carriers for pesticide active ingredients
EP1664030A1 (en) * 2003-09-16 2006-06-07 AstraZeneca AB Quinazoline derivatives
US7553564B2 (en) * 2004-05-26 2009-06-30 Honeywell International Inc. Ternary carbide and nitride materials having tribological applications and methods of making same
US7968503B2 (en) * 2004-06-07 2011-06-28 Ppg Industries Ohio, Inc. Molybdenum comprising nanomaterials and related nanotechnology
US7687112B2 (en) * 2004-07-14 2010-03-30 Kinetitec Corporation Surface for reduced friction and wear and method of making the same
GB0423554D0 (en) * 2004-10-22 2004-11-24 Cancer Rec Tech Ltd Therapeutic compounds
DE102005001198A1 (de) * 2005-01-10 2006-07-20 H.C. Starck Gmbh Metallische Pulvermischungen
US7470307B2 (en) * 2005-03-29 2008-12-30 Climax Engineered Materials, Llc Metal powders and methods for producing the same
US7575619B2 (en) * 2005-03-29 2009-08-18 Hitachi Powdered Metals Co., Ltd. Wear resistant sintered member
TW200801513A (en) 2006-06-29 2008-01-01 Fermiscan Australia Pty Ltd Improved process
EP2097416B1 (en) * 2006-12-18 2012-09-12 Amgen, Inc Azaquinolone based compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
FR2917413B1 (fr) * 2007-06-13 2009-08-21 Sanofi Aventis Sa Derives de 7-alkynyl-1,8-naphthyridones, leur preparation et leur application en therapeutique
FR2917412B1 (fr) 2007-06-13 2009-08-21 Sanofi Aventis Sa Derives de 7-alkynyl, 1,8-naphthyridones, leur preparation et leur application en therapeutique
WO2010000020A1 (en) 2008-06-30 2010-01-07 Cathrx Ltd A catheter
FR2933700B1 (fr) 2008-07-08 2010-07-30 Sanofi Aventis Derives de pyridino-pyridinones, leur preparation et leur application en therapeutique
FR2933701A1 (fr) * 2008-07-08 2010-01-15 Sanofi Aventis Derives anticancereux, leur preparation et leur application en therapeutique
US8038760B1 (en) * 2010-07-09 2011-10-18 Climax Engineered Materials, Llc Molybdenum/molybdenum disulfide metal articles and methods for producing same

Also Published As

Publication number Publication date
TW201004955A (en) 2010-02-01
ZA201100210B (en) 2012-03-28
PE20110405A1 (es) 2011-07-04
EP2315767A2 (fr) 2011-05-04
KR20110031372A (ko) 2011-03-25
NI201100011A (es) 2011-08-05
IL210514A (en) 2013-11-28
NZ590862A (en) 2012-06-29
JP2011527320A (ja) 2011-10-27
CL2011000048A1 (es) 2011-07-15
AU2009267827B2 (en) 2014-01-09
ECSP11010742A (es) 2011-02-28
WO2010004197A2 (fr) 2010-01-14
CN102149713A (zh) 2011-08-10
AR072798A1 (es) 2010-09-22
DOP2011000008A (es) 2011-02-15
ES2438540T3 (es) 2014-01-17
MY149705A (en) 2013-09-30
HK1159108A1 (en) 2012-07-27
CR11866A (es) 2011-03-14
AU2009267827A1 (en) 2010-01-14
HN2011000076A (es) 2013-07-22
FR2933700B1 (fr) 2010-07-30
CA2729833A1 (fr) 2010-01-14
MA32544B1 (fr) 2011-08-01
UY31971A (es) 2010-02-26
MX2011000330A (es) 2011-04-05
CN102149713B (zh) 2013-12-11
EA019362B1 (ru) 2014-03-31
EP2315767B1 (fr) 2013-09-04
JP5606434B2 (ja) 2014-10-15
BRPI0915438A2 (pt) 2015-11-10
IL210514A0 (en) 2011-03-31
WO2010004197A3 (fr) 2010-03-11
EA201170154A1 (ru) 2011-08-30
US8436011B2 (en) 2013-05-07
US20110124643A1 (en) 2011-05-26
SV2011003800A (es) 2011-04-29
FR2933700A1 (fr) 2010-01-15
UA102858C2 (ru) 2013-08-27

Similar Documents

Publication Publication Date Title
CO6341476A2 (es) Derivados de piridino-piridinonas, su preparacion y su aplicacion en terapeutica
UY31152A1 (es) Derivados de 7-alquinil-1,8-naftiridonas, su preparacion y su aplicacion en terapeutica
BR112012018345A2 (pt) "compostos de heteroarila, bem como composições e usos dos mesmos"
CO6491116A2 (es) Derivados de 5-fluoropirimidinona
CR20130001A (es) Derivados de indolizina, su procedimiento de preparación y su aplicación en terapéutica
UY31183A1 (es) Derivados de pirazinona y procesos para su preparación
EA201171293A1 (ru) 3-азабицикло[4.1.0]гептаны, применяемые в качестве антагонистов орексина
UY30881A1 (es) Derivados de fenotiazina, procedimientos y su uso como productos farmacéuticos
UY32517A (es) Derivados de nicotinamida, su preparación y su aplicación en terapéutica
GT201200154A (es) Derivados de piridino-piridinonas, su preparación y su aplicación en terapéutica
ECSP12011653A (es) Derivados de n1-acil-5-fluoropirimidinona
UY29040A1 (es) Procedimiento de amino-tropano, su preparación y aplicación en terapéutica
NI201000023A (es) Derivados de indol-2-ona disustituidos en 3, su preparación y su aplicación en terapéutica.
CR20110701A (es) Derivados de pirazoles, su preparacion y su aplicacion terapeutica.
MX2012010127A (es) Derivados de aminoindanos, su preparacion y su aplicacion en terapeuticos.
CO6501122A2 (es) Nuevos derivados de (heterociclo-piperidina condensada) - (piperazinil)-1-alcanona o de (heterocilco-pirrolidina condensada)-(pieprazinil)-1-alcanona y su utilizacion como inhibidores de p75
CO6300943A2 (es) Derivados de 2-oxo-aquil-1-piperazin-2-ona su preparacion y su aplicacion en terapeutica
UY31139A1 (es) Formas cristalinas de 3-(2r-tetrahidrofuril-metil)-2-tioxantina
DOP2012000146A (es) Nuevos derivados (heterociclo-tetrahidro-piridin)-(piperazinil)-1-alcanona y (heterociclo-dihidro-pirrolidin)-(piperazinil)-1-alcanona y su utilizacion como inhibidores de p75
UY32515A (es) Nuevos derivados anticancerosos de nicotinamida, su preparación y su aplicación terapéutica
UY32516A (es) Derivados anticancerígenos de la nicotinamida, su preparación y su aplicación en terapéutica
SV2008003052A (es) Dimeros de derivados de artemisinina, su preparacion y su aplicacion en terapeutica
TH112532B (th) องค์ประกอบใช้ปรับสภาพเส้นผม

Legal Events

Date Code Title Description
FG Application granted