CO6251209A2 - Esteres ciclicos de boro y composiciones que los contienen - Google Patents

Esteres ciclicos de boro y composiciones que los contienen

Info

Publication number
CO6251209A2
CO6251209A2 CO09145296A CO09145296A CO6251209A2 CO 6251209 A2 CO6251209 A2 CO 6251209A2 CO 09145296 A CO09145296 A CO 09145296A CO 09145296 A CO09145296 A CO 09145296A CO 6251209 A2 CO6251209 A2 CO 6251209A2
Authority
CO
Colombia
Prior art keywords
proviso
unsubstituted
substituted
compositions containing
compounds
Prior art date
Application number
CO09145296A
Other languages
English (en)
Inventor
Stephen Baker
Rashmi Sharma
Vincent Hernandez
James Nieman
Tsutoma Akama
Yong-Kang Zhang
Jacob J Plattner
Michael Richard Alley
Rajesshwar Singh
Fernando Rock
James Phillips
Ming Ha
Xiaosong Lu
Original Assignee
Anacor Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40156702&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO6251209(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Anacor Pharmaceuticals Inc filed Critical Anacor Pharmaceuticals Inc
Publication of CO6251209A2 publication Critical patent/CO6251209A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Esta invención proporciona, entre otras cosas, compuestos novedosos útiles para tratar infecciones bacterianas, composiciones farmacéuticas que contienen tales compuestos, así como combinaciones de estos compuestos con al menos un agente terapéuticamente eficaz adicional. 1.- Un compuesto que tiene una estructura según la fórmula:en la que R* es seleccionado de H y una carga negativa; R3 es seleccionado de H, ciano, nitroalquilo sustituido o no sustituido y aminoalquilo sustituido o no sustituido; Ra es seleccionado de H o -YR5 en el que Y es seleccionado de O y S; R5 es seleccionado de H, alquilo sustituido o no sustituido y heteroalquilo sustituido o no sustituido con la condición de que Ra y R3 no pueden ser ambos H; con la condición de que Ra y R*, junto con los átomos a los que están unidos, se combinan opcionalmente para formar un anillo de heterocicloalquilo sustituido o no sustituido de 6 a 10 miembros; y con la condición de que cuando R3 es H, Ra no tiene una estructura que es seleccionada de: benciloxilo no sustituido, -OCH2COOH, metoxilo, etoxilo con la condición de que cuando Ra es H, R3 no es ciano, o una sal hidrato o solvato del mismo. 2.- El compuesto según a reivindicación 1, que tiene una estructura según la fórmula siguiente:en la que C* es un átomo de carbono con la condición de que cuando R3 no es H, C* es un estereoisómero que tiene una configuración que es seleccionado de (R) y (S).
CO09145296A 2007-06-20 2009-12-18 Esteres ciclicos de boro y composiciones que los contienen CO6251209A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94529407P 2007-06-20 2007-06-20
US4117808P 2008-03-31 2008-03-31

Publications (1)

Publication Number Publication Date
CO6251209A2 true CO6251209A2 (es) 2011-02-21

Family

ID=40156702

Family Applications (1)

Application Number Title Priority Date Filing Date
CO09145296A CO6251209A2 (es) 2007-06-20 2009-12-18 Esteres ciclicos de boro y composiciones que los contienen

Country Status (29)

Country Link
US (4) US7816344B2 (es)
EP (1) EP2164331B1 (es)
JP (3) JP5530923B2 (es)
KR (3) KR101578351B1 (es)
CN (2) CN101772302B (es)
AR (1) AR067105A1 (es)
AU (1) AU2008265630B2 (es)
BR (1) BRPI0813450B8 (es)
CA (1) CA2692135C (es)
CL (1) CL2008001855A1 (es)
CO (1) CO6251209A2 (es)
CR (1) CR11224A (es)
DK (1) DK2164331T3 (es)
DO (1) DOP2009000281A (es)
EA (1) EA020530B1 (es)
ES (1) ES2655299T3 (es)
IL (1) IL202379A (es)
JO (1) JO3396B1 (es)
MA (1) MA31675B1 (es)
MX (1) MX347688B (es)
MY (1) MY162692A (es)
NO (1) NO2164331T3 (es)
NZ (1) NZ582706A (es)
PE (1) PE20090840A1 (es)
SG (1) SG182219A1 (es)
TW (1) TW200911822A (es)
UY (1) UY31171A1 (es)
WO (1) WO2008157726A1 (es)
ZA (2) ZA200909003B (es)

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Also Published As

Publication number Publication date
JP2016040275A (ja) 2016-03-24
US20100292504A1 (en) 2010-11-18
US9796735B2 (en) 2017-10-24
CN104017008A (zh) 2014-09-03
SG182219A1 (en) 2012-07-30
CA2692135C (en) 2017-01-24
EP2164331A1 (en) 2010-03-24
IL202379A (en) 2016-02-29
CR11224A (es) 2010-06-28
CN101772302A (zh) 2010-07-07
NO2164331T3 (es) 2018-04-28
JP6570391B2 (ja) 2019-09-04
AR067105A1 (es) 2009-09-30
DK2164331T3 (da) 2018-01-29
US20180016285A1 (en) 2018-01-18
JP5530923B2 (ja) 2014-06-25
US10533021B2 (en) 2020-01-14
CA2692135A1 (en) 2008-12-24
BRPI0813450B8 (pt) 2021-05-25
PE20090840A1 (es) 2009-07-08
CN101772302B (zh) 2014-05-07
AU2008265630B2 (en) 2013-06-20
KR101685656B1 (ko) 2016-12-12
KR20100051615A (ko) 2010-05-17
JO3396B1 (ar) 2019-10-20
ES2655299T3 (es) 2018-02-19
US8895534B2 (en) 2014-11-25
EA200901617A1 (ru) 2010-06-30
KR20150100945A (ko) 2015-09-02
NZ582706A (en) 2012-07-27
MA31675B1 (fr) 2010-09-01
US7816344B2 (en) 2010-10-19
KR101578351B1 (ko) 2015-12-17
EP2164331A4 (en) 2011-09-07
ZA201104573B (en) 2014-03-26
CL2008001855A1 (es) 2009-05-29
MY162692A (en) 2017-07-14
ZA200909003B (en) 2022-03-30
EA020530B1 (ru) 2014-11-28
IL202379A0 (en) 2010-06-30
JP2010530881A (ja) 2010-09-16
DOP2009000281A (es) 2010-07-31
EP2164331B1 (en) 2017-11-29
WO2008157726A1 (en) 2008-12-24
BRPI0813450A2 (pt) 2014-12-30
TW200911822A (en) 2009-03-16
KR20160049025A (ko) 2016-05-04
MX347688B (es) 2017-05-09
BRPI0813450B1 (pt) 2019-05-07
AU2008265630A1 (en) 2008-12-24
UY31171A1 (es) 2009-04-30
JP2014148531A (ja) 2014-08-21
US20150133402A1 (en) 2015-05-14
US20090227541A1 (en) 2009-09-10

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