CO6190551A2 - Derivado de alquilsulfona - Google Patents
Derivado de alquilsulfonaInfo
- Publication number
- CO6190551A2 CO6190551A2 CO10036274A CO10036274A CO6190551A2 CO 6190551 A2 CO6190551 A2 CO 6190551A2 CO 10036274 A CO10036274 A CO 10036274A CO 10036274 A CO10036274 A CO 10036274A CO 6190551 A2 CO6190551 A2 CO 6190551A2
- Authority
- CO
- Colombia
- Prior art keywords
- group
- substituent groups
- solvates
- salts
- general formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/48—Aldehydo radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/76—Nitrogen atoms to which a second hetero atom is attached
- C07D213/77—Hydrazine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Abstract
1.- Un compuesto caracterizado porque es representado por la fórmula general (I):[en donde R1 representa un grupo alquilo de C1-C6 el cual puede tener 1 a 6 átomos de halógeno como grupos sustituyentes, un grupo alquenilo de C2-C6 que puede tener 1 a 6 átomos de halógeno como grupos sustituyentes, o un grupo cicloalquilo de C3-C7 que puede tener 1 a 6 átomos de halógeno como grupos sustituyentes; R2 representa un grupo heterocíclico aromático monocíclico que contiene nitrógeno de 6 miembros que tiene 1 a 3 grupos sustituyentes, o un grupo heterocíclico bicíclico que contiene nitrógeno de 9 ó 10 miembros que tiene 1 a 4 grupos sustituyentes;Z1, Z2 y Z3 representan cada uno independientemente un átomo de hidrógeno, un átomo de halógeno o un grupo ciano; y n representa 0, 1 ó 2], sales del mismo, o solvatos del mismo. 2.- El compuesto de conformidad con la reivindicación 1, sales del mismo o solvatos del mismo, caracterizado porque R2 en la fórmula general (I) es cualquiera de un grupo seleccionado del grupo que consiste en un grupo piridilo, un grupo triazolopiridilo y un grupo piridopirimidinilo, que tiene 1 a 3 grupos sustituyentes. 3.- El compuesto de conformidad con la reivindicación 1, sales del mismo, o solvatos del mismo, caracterizado porque en la fórmula general (1) es un grupo piridilo que tiene 1 a 3 grupos sustituyentes.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007235580 | 2007-09-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO6190551A2 true CO6190551A2 (es) | 2010-08-19 |
Family
ID=40451983
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO10036274A CO6190551A2 (es) | 2007-09-11 | 2010-03-26 | Derivado de alquilsulfona |
Country Status (14)
Country | Link |
---|---|
US (1) | US20100168136A1 (es) |
EP (1) | EP2204365A4 (es) |
JP (1) | JPWO2009034976A1 (es) |
KR (1) | KR20100057838A (es) |
CN (1) | CN101855209A (es) |
AU (1) | AU2008298307A1 (es) |
BR (1) | BRPI0816800A2 (es) |
CA (1) | CA2698371A1 (es) |
CO (1) | CO6190551A2 (es) |
MX (1) | MX2010002475A (es) |
RU (1) | RU2010113933A (es) |
TW (1) | TW200920362A (es) |
WO (1) | WO2009034976A1 (es) |
ZA (1) | ZA201001727B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108623446A (zh) * | 2017-03-24 | 2018-10-09 | 北京艾德旺科技发展有限公司 | 一种合成3,3-二氟环丁烷甲酸的方法 |
AR121149A1 (es) | 2020-01-30 | 2022-04-20 | Fmc Corp | Compuestos piridina para controlar plagas de invertebrados |
CN111377838B (zh) * | 2020-03-09 | 2021-10-15 | 华东师范大学 | 一种大位阻烷基-烷基砜类化合物及其合成方法和应用 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2682544A (en) * | 1950-09-27 | 1954-06-29 | Sterling Drug Inc | Aryl-pyridylmethyl alkyl sulfones and their preparation |
US4148922A (en) * | 1978-05-04 | 1979-04-10 | Warner-Lambert Company | 3-[2-(Dialkylamino)ethyl]-2-(benzyl)indoles |
JPH0995444A (ja) | 1995-10-02 | 1997-04-08 | Teijin Ltd | アミロイド蛋白凝集阻害剤 |
AU773273B2 (en) | 1999-02-26 | 2004-05-20 | Bristol-Myers Squibb Company | Novel sulfonamide compounds and uses thereof |
EP1268412B8 (en) | 2000-03-20 | 2007-02-21 | MERCK SHARP & DOHME LTD. | Sulphonamido-substituted bridged bicycloalkyl derivatives |
DE60135489D1 (de) | 2000-11-17 | 2008-10-02 | Lilly Co Eli | Lactam dipeptid und dessen verwendung zur inhibierung der beta-amyloid peptid frisetzung |
UA74849C2 (en) | 2000-11-17 | 2006-02-15 | Lilly Co Eli | Lactam |
UA77165C2 (en) | 2000-11-17 | 2006-11-15 | Lilly Co Eli | (n)-((s)-2-hydroxy-3-methyl-butyryl)-1-(l-alaninyl)-(s)-1-amino-3-methyl-4,5,6,7-tetrahydro-2h-3-benzazepin-2-one dihydrate, processes for manufacturing and pharmaceutical composition |
GB0108591D0 (en) | 2001-04-05 | 2001-05-23 | Merck Sharp & Dohme | Therapeutic agents |
GB0108592D0 (en) | 2001-04-05 | 2001-05-23 | Merck Sharp & Dohme | Therapeutic agents |
AU2002324123B2 (en) | 2001-08-21 | 2007-07-12 | Merck Sharp & Dohme (Uk) Limited | Novel cyclohexyl sulphones |
EP1466898A4 (en) * | 2001-12-27 | 2005-12-07 | Daiichi Seiyaku Co | INHIBITORS OF THE PRODUCTION / SEPARATION OF BETA-AMYLOIDS PROTEINS |
CA2526487A1 (en) | 2003-06-30 | 2005-01-06 | Daiichi Pharmaceutical Co., Ltd. | Heterocyclic methyl sulfone derivative |
BRPI0610532A2 (pt) * | 2005-04-08 | 2010-06-29 | Daiichi Sankyo Co Ltd | derivado de piridilmetilsulfona |
EP2114973A1 (en) * | 2007-01-08 | 2009-11-11 | ExxonMobil Chemical Patents Inc. | Methods for oligomerizing olefins with chromium pyridine thioether catalysts |
-
2008
- 2008-09-09 TW TW097134511A patent/TW200920362A/zh unknown
- 2008-09-10 MX MX2010002475A patent/MX2010002475A/es unknown
- 2008-09-10 AU AU2008298307A patent/AU2008298307A1/en not_active Abandoned
- 2008-09-10 WO PCT/JP2008/066279 patent/WO2009034976A1/ja active Application Filing
- 2008-09-10 RU RU2010113933/04A patent/RU2010113933A/ru unknown
- 2008-09-10 CN CN200880116238A patent/CN101855209A/zh active Pending
- 2008-09-10 CA CA2698371A patent/CA2698371A1/en not_active Abandoned
- 2008-09-10 EP EP08830551A patent/EP2204365A4/en not_active Withdrawn
- 2008-09-10 BR BRPI0816800-8A2A patent/BRPI0816800A2/pt not_active Application Discontinuation
- 2008-09-10 JP JP2009532189A patent/JPWO2009034976A1/ja active Pending
- 2008-09-10 KR KR1020107005096A patent/KR20100057838A/ko not_active Application Discontinuation
-
2010
- 2010-03-10 ZA ZA2010/01727A patent/ZA201001727B/en unknown
- 2010-03-11 US US12/722,282 patent/US20100168136A1/en not_active Abandoned
- 2010-03-26 CO CO10036274A patent/CO6190551A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US20100168136A1 (en) | 2010-07-01 |
WO2009034976A1 (ja) | 2009-03-19 |
CN101855209A (zh) | 2010-10-06 |
MX2010002475A (es) | 2010-03-29 |
EP2204365A1 (en) | 2010-07-07 |
KR20100057838A (ko) | 2010-06-01 |
CA2698371A1 (en) | 2009-03-19 |
ZA201001727B (en) | 2010-11-24 |
RU2010113933A (ru) | 2011-10-20 |
TW200920362A (en) | 2009-05-16 |
AU2008298307A1 (en) | 2009-03-19 |
JPWO2009034976A1 (ja) | 2010-12-24 |
EP2204365A4 (en) | 2012-02-22 |
BRPI0816800A2 (pt) | 2015-03-03 |
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Legal Events
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FC | Application refused |