CO6180502A2 - Comprimido masticable que contiene fenilefrina - Google Patents

Comprimido masticable que contiene fenilefrina

Info

Publication number
CO6180502A2
CO6180502A2 CO09006117A CO09006117A CO6180502A2 CO 6180502 A2 CO6180502 A2 CO 6180502A2 CO 09006117 A CO09006117 A CO 09006117A CO 09006117 A CO09006117 A CO 09006117A CO 6180502 A2 CO6180502 A2 CO 6180502A2
Authority
CO
Colombia
Prior art keywords
composition
isoquinolines
derivatives
acid
phenylephrine
Prior art date
Application number
CO09006117A
Other languages
English (en)
Inventor
Josephine Fubara
Mark Mabry
Aaron Durr
Lewis Taylor
Amanda Alley
David Giamalva
Manish Agrawal
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of CO6180502A2 publication Critical patent/CO6180502A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Abstract

1.- Una composición masticable que comprende: a) fenilefrina o una sal farmacéuticamente aceptable de ésta; b) un endulzante artificial; y c) una matriz sustancialmente libre de aldehído. 2.- La composición de la reivindicación 1, en donde la composición comprende además menos de 2.5% p/p de isoquinolinas total y mantiene dicho nivel de isoquinolinas durante por lo menos 24 meses. 3.- La composición de la reivindicación 2, en donde la composición comprende además de menos de 1.5% p/p de isoquinolinas total y mantiene dicho nivel de isoquinolinas durante por lo menos 24 meses. 4.- La composición de una cualquiera de las reivindicaciones 1 a 3, que comprende además por lo menos un segundo activo farmacéutico. 5.- La composición de la reivindicación 4, en donde por lo menos un Segundo agente activo se selecciona del grupo que consiste de analgésicos, descongestionantes, expectorantes, antitusígenos, antipiréticos, agentes antiinflamatorios, supresores de la tos y antihistamínicos. 6.- La composición de la reivindicación 5, en donde por lo menos un segundo agente activo se selecciona del grupo que consiste de fármacos antiinflamatorios no asteroides (NSAIDS), derivados de ácido propiónico, ibuprofeno, naproxeno, cetoprofeno, flurbiprofeno, fenoprofenoo, suprofenoo, fluprofeno, fenbufeno; derivados de ácido acético, tolmetin sodio, zomepirac, sulindac, indometacina, derivados de ácido fenámico, meclofenamato sodio de ácido mefanámico, derivados de ácido bifenil carboxílico, diflunisal, flufenisal, oxicams, piroxicam, sudoxicam, isoxicam, clorfeniramina, bromfeniramina; dexclorfeniramina, dexbromfeniramina, triprolidina, clorciclizina, difenidramina, doxilamina, tripelenamina, ciproheptatina, bromodifenidramina, fenindamina, pirilamina, azatadina, acrivastina, astemizol, azelastina, cetirizina, ebastina, fexofenadina, cetotifeno, carbinoxamina, desloratadina, loratadina, feniramina, tonzilamina, mizolastina, terfenadina, clofendianol, caramifeno, dextrometorfan, difenidramina, codeina, hidrocodona, seudoefedrina, efedrina, fenilefrina, fenilpropenolamina, hidrato de terpin, guaifenesina, potasio, guaicolsulfonato de potasio, inhibidores Cox 2, Celecoxib, Rofecoxib, Valdecoxib, aspirina, acetaminofen, fenacetina, sales de salicilato y combinaciones de éstos.
CO09006117A 2006-07-25 2009-01-23 Comprimido masticable que contiene fenilefrina CO6180502A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/492,656 US9005652B2 (en) 2006-07-25 2006-07-25 Chewable tablet containing phenylephrine

Publications (1)

Publication Number Publication Date
CO6180502A2 true CO6180502A2 (es) 2010-07-19

Family

ID=38617929

Family Applications (1)

Application Number Title Priority Date Filing Date
CO09006117A CO6180502A2 (es) 2006-07-25 2009-01-23 Comprimido masticable que contiene fenilefrina

Country Status (16)

Country Link
US (2) US9005652B2 (es)
EP (1) EP2043619A2 (es)
JP (1) JP2009544699A (es)
KR (1) KR20090033390A (es)
CN (1) CN101505738A (es)
AU (1) AU2007277314A1 (es)
BR (1) BRPI0715536A2 (es)
CA (1) CA2658629C (es)
CO (1) CO6180502A2 (es)
EC (1) ECSP099086A (es)
IL (1) IL196668A0 (es)
MX (1) MX2009000931A (es)
RU (1) RU2009103636A (es)
SG (1) SG173410A1 (es)
WO (1) WO2008013710A2 (es)
ZA (1) ZA200900565B (es)

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TWI405567B (zh) * 2006-06-01 2013-08-21 Merck Sharp & Dohme 持續釋放脫羥腎上腺素之醫藥組合物
CN101472561A (zh) * 2006-06-01 2009-07-01 先灵公司 去氧肾上腺素脉冲释放制剂和药物组合物
BRPI0712532A2 (pt) * 2006-06-01 2013-04-02 Schering Plough Healthcare Prod Inc formulaÇÕes e composiÇÕes farmacÊuticas de fenilefrina para absorÇço colânica
NZ573174A (en) * 2006-06-01 2012-01-12 Msd Consumer Care Inc Sustained release pharmaceutical dosage form containing phenylephrine
CN101848706A (zh) * 2007-06-01 2010-09-29 先灵-普劳健康护理产品公司 包含底物和含活性成分和聚乙烯醇的包衣的药用组合物
US9149429B2 (en) * 2007-11-21 2015-10-06 The Procter & Gamble Company Preparations, methods and kits useful for the treatment of cough
PE20091084A1 (es) * 2007-12-07 2009-07-23 Schering Plough Healthcare Formulaciones farmaceuticas de fenilefrina y composiciones para absorcion transmucosal
CA2802362C (en) * 2010-06-11 2017-11-21 Gm Pharmaceuticals, Inc. Pharmaceutical compositions for alleviating upper respiratory and oral-pharyngeal congestion
EP2956120B1 (en) 2013-02-13 2020-04-15 The Procter and Gamble Company Anise flavored medication
CA3042642A1 (en) 2013-08-12 2015-02-19 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
CN104434868A (zh) * 2013-09-18 2015-03-25 重庆圣华曦药业股份有限公司 一种稳定且利于在消化道溶出的屈昔多巴口服剂型
US10172797B2 (en) 2013-12-17 2019-01-08 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
WO2015137829A1 (en) * 2014-03-12 2015-09-17 Angeles Relinda G Stable and palatable liquid pharmaceutical composition of phenylephrine and a maleate salt of an antihistamine
CA2955229C (en) 2014-07-17 2020-03-10 Pharmaceutical Manufacturing Research Services, Inc. Immediate release abuse deterrent liquid fill dosage form
WO2016064873A1 (en) 2014-10-20 2016-04-28 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
CN104983732B (zh) * 2015-05-28 2018-05-04 华润三九医药股份有限公司 一种布洛肾素那敏片及其制备方法
AU2017331369B2 (en) 2016-09-26 2019-11-21 The Procter & Gamble Company Extended relief dosage form
US20210378990A1 (en) * 2020-06-06 2021-12-09 Gm Pharmaceuticals, Inc. Compositions containing chlophedianol and menthol

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Also Published As

Publication number Publication date
IL196668A0 (en) 2009-11-18
WO2008013710A2 (en) 2008-01-31
CN101505738A (zh) 2009-08-12
ECSP099086A (es) 2009-02-27
US20150182478A1 (en) 2015-07-02
US9005652B2 (en) 2015-04-14
RU2009103636A (ru) 2010-08-27
ZA200900565B (en) 2009-12-30
CA2658629A1 (en) 2008-01-31
BRPI0715536A2 (pt) 2013-05-07
AU2007277314A1 (en) 2008-01-31
US20080026055A1 (en) 2008-01-31
EP2043619A2 (en) 2009-04-08
WO2008013710A3 (en) 2008-07-24
JP2009544699A (ja) 2009-12-17
SG173410A1 (en) 2011-08-29
KR20090033390A (ko) 2009-04-02
CA2658629C (en) 2015-07-14
MX2009000931A (es) 2009-02-04

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