CO5690597A2 - Derivados de hexahidropirazino[1,2-a]pirimidina-4,7-diona sustituidos, metodo para producirlos y sus uso cxomo medicamentos - Google Patents
Derivados de hexahidropirazino[1,2-a]pirimidina-4,7-diona sustituidos, metodo para producirlos y sus uso cxomo medicamentosInfo
- Publication number
- CO5690597A2 CO5690597A2 CO05079789A CO05079789A CO5690597A2 CO 5690597 A2 CO5690597 A2 CO 5690597A2 CO 05079789 A CO05079789 A CO 05079789A CO 05079789 A CO05079789 A CO 05079789A CO 5690597 A2 CO5690597 A2 CO 5690597A2
- Authority
- CO
- Colombia
- Prior art keywords
- alkyl
- alkylene
- coo
- aryl
- substituted
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Addiction (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Anesthesiology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Urology & Nephrology (AREA)
- Child & Adolescent Psychology (AREA)
Abstract
1.- Un compuesto de la fórmula I en la que los significados son A anillo mono, bi o espirobicíclico de 3-12 miembros que puede comprender uno o más heteroátomos del grupo de N, O y S, y el anillo de 3-12 miembros puede tener sustituyentes adicionales tales como F, CI, Br, NO2, CF3, OCF3, CN, alquilo (C1-C6), arilo, CON(R11)(R12), N(R13)(R14), OH, O-alquilo(C1-C6)-, S-alquilo(C1-C6)-, N(R15)CO-alquilo(C1-C6)- o COO-alquilo(C1-C6)-;R11, R12, R13, R14, R15 independientemente entre sí H, alquilo (C1-C6), heterociclo;n 0,1;m 0,1, 2, 3, 4, 5, 6;R1 R8, alquilen(C1-C6)-R8, alquenilen(C2-C6)-R9, (SO2)-R8, (SO2)-alquilen(C1-C6)-R8, (SO2)-alquenilen(C2-C6)-R9, -(C=O)-R8, (C=O)alquilen(C1-C6)-R8, (C=O)NH-R8, (C=O)-alquenilen(C2-C6)-R9, (C=O)NH-alquilen(C1-C6)-R8, (C=O)-NH-alquenilen(C2-C6)-R9, COO-R8, COO-alquilen(C1-C6)-R8, COO-alquenilen(C2-C6)-R9, alquinilen-R9, (alquil-C1-C4)-heterociclo, donde los grupos alquileno pueden estar sustituidos con F;R8, R9 independientemente entre sí H, F, CI, Br, I, OH, CF3, arilo, heterociclo, cicloalquilo (C3-C8), donde los anillos o sistemas de anillos pueden estar sustituidos hasta 3 veces con F, CI, Br, I, OH, CF3, NO2, CN, OCF3, O-alquilo(C1-C6)-, alquilo (C1-C6), NH2, CON(R11)(R12), N(R13)(R14), SO2-CH3, COOH, COO-alquilo(C1-C6)-, CONH2;R2 H, F, CI, Br, I, OH, CF3, CN, OCF3, O-alquilo(C1-C6)-, O-alcoxi(C1-C4)alquilo(C1-C4)-, S-alquilo(C1-C6)-, alquilo (C1-C6)-, alquenilo (C2-C6), cicloalquilo (C3-C8), O-cicloalquilo(C3-C8)-, cicloalquenilo (C3-C8), O-cicloalquenilo(C3-C8)-, alquinilo (C2-C6)-, arilo, O-arilo, alquilen(C1-C8)arilo, O-alquilen(C1-C8)-arilo, S-arilo, CON(R11)(R12), N(R13)(R14), alquil(C1-C6)-N(R13)(R14), COOH, COO-alquilo(C1-C6))2, COOalquenilo(C1-C6)-, ...
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10305885A DE10305885A1 (de) | 2003-02-13 | 2003-02-13 | Substituierte Hexahydro-pyrazino(1,2-a)pyrimidin-4,7-dionderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| DE10349672A DE10349672A1 (de) | 2003-10-24 | 2003-10-24 | Substituierte Hexahydro-pyrazino(1,2-a)pyrimidin-4,7-dionderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5690597A2 true CO5690597A2 (es) | 2006-10-31 |
Family
ID=32870334
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO05079789A CO5690597A2 (es) | 2003-02-13 | 2005-08-11 | Derivados de hexahidropirazino[1,2-a]pirimidina-4,7-diona sustituidos, metodo para producirlos y sus uso cxomo medicamentos |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1599480B1 (es) |
| JP (1) | JP2006517550A (es) |
| KR (1) | KR20050111588A (es) |
| AR (1) | AR043155A1 (es) |
| AT (1) | ATE472548T1 (es) |
| AU (1) | AU2004212042A1 (es) |
| BR (1) | BRPI0407507A (es) |
| CA (1) | CA2515735A1 (es) |
| CO (1) | CO5690597A2 (es) |
| DE (1) | DE502004011328D1 (es) |
| HR (1) | HRP20050712A2 (es) |
| MA (1) | MA27654A1 (es) |
| MX (1) | MXPA05007516A (es) |
| MY (1) | MY135902A (es) |
| NO (1) | NO20054085L (es) |
| PE (1) | PE20050192A1 (es) |
| PL (1) | PL377227A1 (es) |
| RS (1) | RS20050564A (es) |
| RU (1) | RU2005128497A (es) |
| TW (1) | TW200508235A (es) |
| WO (1) | WO2004072076A1 (es) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7566711B2 (en) | 2001-10-12 | 2009-07-28 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| US8080657B2 (en) | 2001-10-12 | 2011-12-20 | Choongwae Pharma Corporation | Compounds of reverse turn mimetics and the use thereof |
| US20040072831A1 (en) * | 2001-10-12 | 2004-04-15 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| US7576084B2 (en) | 2001-10-12 | 2009-08-18 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| US7232822B2 (en) | 2001-10-12 | 2007-06-19 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| US7671054B1 (en) | 2001-10-12 | 2010-03-02 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| KR20050100686A (ko) * | 2003-02-13 | 2005-10-19 | 사노피-아벤티스 도이칠란트 게엠베하 | 질소-치환된헥사하이드로피라지노[1,2-ａ]피리미딘-4,7-디온 유도체,이의 제조방법 및 의약으로서의 이의 용도 |
| DE102004042441A1 (de) * | 2004-08-31 | 2006-04-06 | Sanofi-Aventis Deutschland Gmbh | Mit Aminosäuren substituierte Hexahydro-pyrazino(1,2-a)pyrimidin-4,7-dionderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| JP2008545009A (ja) | 2005-06-30 | 2008-12-11 | プロシディオン・リミテッド | Ｇｐｃｒアゴニスト |
| EP1957516B1 (en) | 2005-11-08 | 2016-03-09 | Choongwae Pharma Corporation | Alfa-helix mimetics and method relating to the treatment of cancer stem cells |
| US20080009500A1 (en) * | 2005-11-08 | 2008-01-10 | Michael Kahn | Alpha-helix mimetics and methods relating to the treatment of fibrotic disorders |
| WO2008017381A1 (de) | 2006-08-08 | 2008-02-14 | Sanofi-Aventis | Arylaminoaryl-alkyl-substituierte imidazolidin-2,4-dione, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und ihre verwendung |
| SI2114933T1 (sl) | 2007-01-04 | 2012-01-31 | Prosidion Ltd Windrush Court | Piperidinski gpcr-agonisti |
| BRPI0806312A2 (pt) | 2007-01-04 | 2011-09-06 | Prosidion Ltd | agonistas cgpr piperidina |
| CL2008000017A1 (es) | 2007-01-04 | 2008-08-01 | Prosidion Ltd | Compuestos derivados de heterociclos de nitrogeno y oxigeno, agonistas de gpcr; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la obesidad, diabetes, sindrome metabolico, hiperlipidemia, toleranci |
| GB0700122D0 (en) | 2007-01-04 | 2007-02-14 | Prosidion Ltd | GPCR agonists |
| AR064735A1 (es) | 2007-01-04 | 2009-04-22 | Prosidion Ltd | Agonistas de gpcr y composicion farmaceutica en base al compuesto |
| EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| GB0720390D0 (en) | 2007-10-18 | 2007-11-28 | Prosidion Ltd | G-Protein coupled receptor agonists |
| GB0720389D0 (en) | 2007-10-18 | 2008-11-12 | Prosidion Ltd | G-Protein Coupled Receptor Agonists |
| US8470841B2 (en) | 2008-07-09 | 2013-06-25 | Sanofi | Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof |
| WO2010068601A1 (en) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof |
| CA2771278A1 (en) | 2009-08-26 | 2011-03-03 | Sanofi | Novel crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use |
| US8901114B2 (en) | 2011-03-08 | 2014-12-02 | Sanofi | Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof |
| US8809325B2 (en) | 2011-03-08 | 2014-08-19 | Sanofi | Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof |
| EP2683704B1 (de) | 2011-03-08 | 2014-12-17 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| WO2012120054A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
| EP2683702B1 (de) | 2011-03-08 | 2014-12-24 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP2683701B1 (de) | 2011-03-08 | 2014-12-24 | Sanofi | Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2683703B1 (de) | 2011-03-08 | 2015-05-27 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP2683699B1 (de) | 2011-03-08 | 2015-06-24 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6184223B1 (en) * | 1995-10-27 | 2001-02-06 | Molecumetics Ltd. | Reverse-turn mimetics and methods relating thereto |
| US6251902B1 (en) * | 1997-06-25 | 2001-06-26 | Pfizer Inc. | Dipeptide derivatives as growth hormone secretagogues |
| US6294525B1 (en) * | 1999-09-01 | 2001-09-25 | Molecumetics Ltd. | Reverse-turn mimetics and methods relating thereto |
| KR20050100686A (ko) * | 2003-02-13 | 2005-10-19 | 사노피-아벤티스 도이칠란트 게엠베하 | 질소-치환된헥사하이드로피라지노[1,2-ａ]피리미딘-4,7-디온 유도체,이의 제조방법 및 의약으로서의 이의 용도 |
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2004
- 2004-01-29 WO PCT/EP2004/000769 patent/WO2004072076A1/de active Application Filing
- 2004-01-29 RU RU2005128497/04A patent/RU2005128497A/ru not_active Application Discontinuation
- 2004-01-29 PL PL377227A patent/PL377227A1/pl not_active Application Discontinuation
- 2004-01-29 JP JP2006501649A patent/JP2006517550A/ja active Pending
- 2004-01-29 AU AU2004212042A patent/AU2004212042A1/en not_active Abandoned
- 2004-01-29 AT AT04706170T patent/ATE472548T1/de not_active IP Right Cessation
- 2004-01-29 DE DE502004011328T patent/DE502004011328D1/de not_active Expired - Lifetime
- 2004-01-29 EP EP04706170A patent/EP1599480B1/de not_active Expired - Lifetime
- 2004-01-29 KR KR1020057014859A patent/KR20050111588A/ko not_active Application Discontinuation
- 2004-01-29 MX MXPA05007516A patent/MXPA05007516A/es not_active Application Discontinuation
- 2004-01-29 RS YUP-2005/0564A patent/RS20050564A/sr unknown
- 2004-01-29 CA CA002515735A patent/CA2515735A1/en not_active Abandoned
- 2004-01-29 BR BRPI0407507-2A patent/BRPI0407507A/pt not_active IP Right Cessation
- 2004-02-09 PE PE2004000147A patent/PE20050192A1/es not_active Application Discontinuation
- 2004-02-11 AR ARP040100427A patent/AR043155A1/es unknown
- 2004-02-11 TW TW093103121A patent/TW200508235A/zh unknown
- 2004-02-12 MY MYPI20040456A patent/MY135902A/en unknown
-
2005
- 2005-08-11 MA MA28428A patent/MA27654A1/fr unknown
- 2005-08-11 CO CO05079789A patent/CO5690597A2/es not_active Application Discontinuation
- 2005-08-12 HR HR20050712A patent/HRP20050712A2/xx not_active Application Discontinuation
- 2005-09-02 NO NO20054085A patent/NO20054085L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1599480A1 (de) | 2005-11-30 |
| DE502004011328D1 (de) | 2010-08-12 |
| PE20050192A1 (es) | 2005-04-01 |
| HRP20050712A2 (en) | 2006-09-30 |
| ATE472548T1 (de) | 2010-07-15 |
| CA2515735A1 (en) | 2004-08-26 |
| JP2006517550A (ja) | 2006-07-27 |
| AR043155A1 (es) | 2005-07-20 |
| RS20050564A (en) | 2007-09-21 |
| EP1599480B1 (de) | 2010-06-30 |
| MXPA05007516A (es) | 2006-01-27 |
| MA27654A1 (fr) | 2005-12-01 |
| BRPI0407507A (pt) | 2006-02-14 |
| NO20054085L (no) | 2005-09-02 |
| TW200508235A (en) | 2005-03-01 |
| WO2004072076A1 (de) | 2004-08-26 |
| MY135902A (en) | 2008-07-31 |
| PL377227A1 (pl) | 2006-01-23 |
| AU2004212042A1 (en) | 2004-08-26 |
| RU2005128497A (ru) | 2006-01-27 |
| KR20050111588A (ko) | 2005-11-25 |
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| Date | Code | Title | Description |
|---|---|---|---|
| FC | Application refused |