CO5690596A2 - Derivados de hexahidropirazino [1,2-a]pirimidin-4,7-diona sustituidos, en el nitrogeno, metodo para su produccion y su uso como medicamentos - Google Patents
Derivados de hexahidropirazino [1,2-a]pirimidin-4,7-diona sustituidos, en el nitrogeno, metodo para su produccion y su uso como medicamentosInfo
- Publication number
- CO5690596A2 CO5690596A2 CO05079786A CO05079786A CO5690596A2 CO 5690596 A2 CO5690596 A2 CO 5690596A2 CO 05079786 A CO05079786 A CO 05079786A CO 05079786 A CO05079786 A CO 05079786A CO 5690596 A2 CO5690596 A2 CO 5690596A2
- Authority
- CO
- Colombia
- Prior art keywords
- alkyl
- alkenylene
- coo
- heterocycle
- alkylene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Reproductive Health (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
1.- Un compuesto de la fórmula I en la que los significados son A anillo mono, bi o espirobiclclico de 3-12 miembros que puede comprender uno o más heteroátomos del grupo de N, O Y S y cuyo anillo de 3-12 miembros puede tener sustituyentes adicionales tales como F, CI, Br, NO2, CF3, O CF3, CN, alquilo (C1-C6), arilo, CON(R11)(R12), N(R13)(R14), OH, O-alquilo(C1-C6), S-alquilo(C1-C6), N(R15)CO-alquilo(C1-C6) o COO-alquilo(C1-C6);R11, R12, R13, R14, R15 independientemente entre sí H, alquilo (C1-C6), heterociclo;n 0,1;m 0,1,2,3,4,5,6;R1 R8, alquilen(C1-C6)-R8, alquenilen(C2-C6)-R9, (SO2)-R8, (SO2)alquilen(C1-C6)-R8, (SO2)-alquenilen(C2-C6)-R9, (C=O)-R8, (C=O)-alquilen(C1-C6)-R8, (C=O)NH-R8, (C=O)-alquenilen(C2-C6)-R9, (C=O)-NH-alquilen(C1-C6)-R8, (C=O)-NH-alquenilen(C2-C6)-R9, COO-R8, COO-alquilen(C1-C6)-R8, COO-alquenilen(C2-C6)-R9, alquinilen-R9, (alquil-C1-C4)-heterociclo, donde los grupos alquileno pueden estar sustituidos con F;R8, R9 independientemente entre sí H, F, CI, Br, I, OH, CF3, arilo, heterociclo, cicloalquilo (C3-C8), donde los anillos o sistemas de anillos pueden estar sustituidos hasta 3 veces con F, CI, Br, I, OH, CF3, NO2, CN, OCF3, O-alquilo{C1-C6), alquilo (C1-C6), NH2, CON(R11)(R12), N(R13)(R14), SO2-CH3, COOH, COO-alquilo(C1-C6), CONH2;R2 NH2, NO2, N(R13)(R14), NH-SO2CH3, NH-SO2-R12, NR11-SO2-R12, N(CO)R11, un heterociclo que contiene nitrógeno, donde el heterociclo está unido por un átomo de nitrógeno, NHCONR11, N(alquil-C1-C6)N+(alquilo-C1-C4)3;R3, R4, R5 independientemente entre si H, F, CI, Br, I, OH, CF3, NO2, CN, OCF3, O-alquilo(C1-C6), O-aIcoxi(C1-C4)-alquilo(C1-C6), S-alquilo(C1-C6), alquilo (C1-C6), alquenilo (C2-C6), cicloalquilo (C3-C8), ...
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10305885A DE10305885A1 (de) | 2003-02-13 | 2003-02-13 | Substituierte Hexahydro-pyrazino(1,2-a)pyrimidin-4,7-dionderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| DE10349671A DE10349671A1 (de) | 2003-10-24 | 2003-10-24 | Stickstoff substituierte Hexahydro-pyrazino(1,2-a)pyrimidin-4,7-dionderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5690596A2 true CO5690596A2 (es) | 2006-10-31 |
Family
ID=32870333
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO05079786A CO5690596A2 (es) | 2003-02-13 | 2005-08-11 | Derivados de hexahidropirazino [1,2-a]pirimidin-4,7-diona sustituidos, en el nitrogeno, metodo para su produccion y su uso como medicamentos |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP1597259B1 (es) |
| JP (1) | JP2006517551A (es) |
| KR (1) | KR20050100686A (es) |
| AR (1) | AR043154A1 (es) |
| AT (1) | ATE393769T1 (es) |
| AU (1) | AU2004212043A1 (es) |
| BR (1) | BRPI0407387A (es) |
| CA (1) | CA2514791A1 (es) |
| CO (1) | CO5690596A2 (es) |
| DE (1) | DE502004007000D1 (es) |
| HR (1) | HRP20050711A2 (es) |
| MA (1) | MA27734A1 (es) |
| MX (1) | MXPA05008288A (es) |
| NO (1) | NO20054208L (es) |
| PE (1) | PE20040949A1 (es) |
| PL (1) | PL377660A1 (es) |
| RS (1) | RS20050572A (es) |
| RU (1) | RU2005128499A (es) |
| TW (1) | TW200510417A (es) |
| WO (1) | WO2004072077A1 (es) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7671054B1 (en) | 2001-10-12 | 2010-03-02 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| US8080657B2 (en) | 2001-10-12 | 2011-12-20 | Choongwae Pharma Corporation | Compounds of reverse turn mimetics and the use thereof |
| US20040072831A1 (en) * | 2001-10-12 | 2004-04-15 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| US7232822B2 (en) | 2001-10-12 | 2007-06-19 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| US7576084B2 (en) | 2001-10-12 | 2009-08-18 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| US7566711B2 (en) | 2001-10-12 | 2009-07-28 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| BRPI0407507A (pt) * | 2003-02-13 | 2006-02-14 | Aventis Pharma Gmbh | derivados de hexahidro-pirazino[1,2-a]pirimidin-4,7-diona, processos para sua preparação de sua aplicação como medicamento |
| DE102004042441A1 (de) * | 2004-08-31 | 2006-04-06 | Sanofi-Aventis Deutschland Gmbh | Mit Aminosäuren substituierte Hexahydro-pyrazino(1,2-a)pyrimidin-4,7-dionderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| EP2308840A1 (en) | 2005-06-30 | 2011-04-13 | Prosidion Limited | GPCR agonists |
| JP5102985B2 (ja) * | 2006-07-18 | 2012-12-19 | 東ソ−・エフテック株式会社 | 含フッ素２級アミン化合物の製造方法 |
| EP2061767B1 (de) | 2006-08-08 | 2014-12-17 | Sanofi | Arylaminoaryl-alkyl-substituierte Imidazolidin-2,4-dione, Verfahren zu ihrer Herstellung, diese Verbindungen enthaltende Arzneimittel und ihre Verwendung |
| GB0700122D0 (en) | 2007-01-04 | 2007-02-14 | Prosidion Ltd | GPCR agonists |
| AR064735A1 (es) | 2007-01-04 | 2009-04-22 | Prosidion Ltd | Agonistas de gpcr y composicion farmaceutica en base al compuesto |
| PE20081849A1 (es) | 2007-01-04 | 2009-01-26 | Prosidion Ltd | Derivados de piperidin-4-il-propoxi-benzamida como agonistas de gpcr |
| EA016507B1 (ru) | 2007-01-04 | 2012-05-30 | Прозидион Лимитед | Пиперидиновые агонисты gpcr |
| EA015129B1 (ru) | 2007-01-04 | 2011-06-30 | Прозидион Лимитед | Пиперидиновые агонисты gpcr |
| JP5204438B2 (ja) * | 2007-07-31 | 2013-06-05 | 東ソ−・エフテック株式会社 | 含フッ素アミン化合物の製造方法 |
| EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| GB0720390D0 (en) | 2007-10-18 | 2007-11-28 | Prosidion Ltd | G-Protein coupled receptor agonists |
| GB0720389D0 (en) | 2007-10-18 | 2008-11-12 | Prosidion Ltd | G-Protein Coupled Receptor Agonists |
| WO2010003624A2 (en) | 2008-07-09 | 2010-01-14 | Sanofi-Aventis | Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof |
| EP2346871A1 (en) * | 2008-10-14 | 2011-07-27 | PRISM BioLab Corporation | Alpha helix mimetics in the treatment of cancer |
| WO2010068601A1 (en) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof |
| EP2427451B1 (en) | 2009-05-07 | 2019-03-20 | PRISM BioLab Co., Ltd. | Alpha helix mimetics and methods relating thereto |
| CN102482312A (zh) | 2009-08-26 | 2012-05-30 | 赛诺菲 | 新颖的杂芳族氟代糖苷结晶水合物、含有这些化合物的药物和它们的用途 |
| WO2012120053A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| WO2012120054A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| WO2012120055A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| WO2012120056A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2683702B1 (de) | 2011-03-08 | 2014-12-24 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP2683703B1 (de) | 2011-03-08 | 2015-05-27 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP2683698B1 (de) | 2011-03-08 | 2017-10-04 | Sanofi | Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| WO2012120058A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| US8901114B2 (en) | 2011-03-08 | 2014-12-02 | Sanofi | Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof |
| US20190151324A1 (en) | 2016-06-23 | 2019-05-23 | University Of Maryland, Baltimore | NON-CATALYTIC SUBSTRATE-SELECTIVE P38alpha-SPECIFIC MAPK INHIBITORS WITH ENDOTHELIAL-STABILIZING AND ANTI-INFLAMMATORY ACTIVITY, AND METHODS OF USE THEREOF |
| CN113395963B (zh) | 2018-12-07 | 2024-06-25 | 马里兰大学巴尔的摩分校 | 非ATP/催化位点p38丝裂原活化蛋白激酶抑制剂 |
| AU2021274475B2 (en) * | 2020-05-18 | 2024-03-21 | Gen1E Lifesciences Inc. | P38alpha mitogen-activated protein kinase inhibitors |
| CA3196286A1 (en) | 2020-10-29 | 2022-05-05 | Adam Galan | Crystalline 5-(dimethylamino)-n-(4-(morpholinomethyl)phenyl) naphthalene-1-sulfonamide di-hydrochloride di-hydrate |
| CA3213095A1 (en) | 2021-03-23 | 2022-09-29 | Adam Galan | Substituted naphthyl p38alpha mitogen-activated protein kinase inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6184223B1 (en) * | 1995-10-27 | 2001-02-06 | Molecumetics Ltd. | Reverse-turn mimetics and methods relating thereto |
| AU7445498A (en) * | 1997-06-25 | 1999-01-04 | Pfizer Inc. | Dipeptide derivatives as growth hormone secretagogues |
| US6294525B1 (en) * | 1999-09-01 | 2001-09-25 | Molecumetics Ltd. | Reverse-turn mimetics and methods relating thereto |
| BRPI0407507A (pt) * | 2003-02-13 | 2006-02-14 | Aventis Pharma Gmbh | derivados de hexahidro-pirazino[1,2-a]pirimidin-4,7-diona, processos para sua preparação de sua aplicação como medicamento |
-
2004
- 2004-01-29 JP JP2006501650A patent/JP2006517551A/ja active Pending
- 2004-01-29 RU RU2005128499/04A patent/RU2005128499A/ru not_active Application Discontinuation
- 2004-01-29 MX MXPA05008288A patent/MXPA05008288A/es not_active Application Discontinuation
- 2004-01-29 BR BR0407387-8A patent/BRPI0407387A/pt not_active IP Right Cessation
- 2004-01-29 WO PCT/EP2004/000770 patent/WO2004072077A1/de active IP Right Grant
- 2004-01-29 PL PL377660A patent/PL377660A1/pl unknown
- 2004-01-29 DE DE502004007000T patent/DE502004007000D1/de not_active Expired - Lifetime
- 2004-01-29 EP EP04706145A patent/EP1597259B1/de not_active Expired - Lifetime
- 2004-01-29 AU AU2004212043A patent/AU2004212043A1/en not_active Abandoned
- 2004-01-29 AT AT04706145T patent/ATE393769T1/de not_active IP Right Cessation
- 2004-01-29 RS YUP-2005/0572A patent/RS20050572A/sr unknown
- 2004-01-29 KR KR1020057014986A patent/KR20050100686A/ko not_active Application Discontinuation
- 2004-01-29 CA CA002514791A patent/CA2514791A1/en not_active Abandoned
- 2004-02-11 TW TW093103120A patent/TW200510417A/zh unknown
- 2004-02-11 AR ARP040100426A patent/AR043154A1/es unknown
- 2004-02-11 PE PE2004000150A patent/PE20040949A1/es not_active Application Discontinuation
-
2005
- 2005-08-11 CO CO05079786A patent/CO5690596A2/es not_active Application Discontinuation
- 2005-08-11 MA MA28429A patent/MA27734A1/fr unknown
- 2005-08-12 HR HR20050711A patent/HRP20050711A2/xx not_active Application Discontinuation
- 2005-09-09 NO NO20054208A patent/NO20054208L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2514791A1 (en) | 2004-08-26 |
| NO20054208L (no) | 2005-09-09 |
| KR20050100686A (ko) | 2005-10-19 |
| JP2006517551A (ja) | 2006-07-27 |
| DE502004007000D1 (de) | 2008-06-12 |
| TW200510417A (en) | 2005-03-16 |
| AU2004212043A1 (en) | 2004-08-26 |
| MXPA05008288A (es) | 2006-03-21 |
| PE20040949A1 (es) | 2005-01-12 |
| MA27734A1 (fr) | 2006-02-01 |
| WO2004072077A1 (de) | 2004-08-26 |
| RS20050572A (en) | 2007-09-21 |
| PL377660A1 (pl) | 2006-02-06 |
| EP1597259B1 (de) | 2008-04-30 |
| ATE393769T1 (de) | 2008-05-15 |
| BRPI0407387A (pt) | 2006-02-07 |
| HRP20050711A2 (en) | 2006-09-30 |
| AR043154A1 (es) | 2005-07-20 |
| RU2005128499A (ru) | 2006-01-27 |
| EP1597259A1 (de) | 2005-11-23 |
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