CO5570656A2 - Liberacin controlada de una sustancia activa a un entorno rico en grasa - Google Patents
Liberacin controlada de una sustancia activa a un entorno rico en grasaInfo
- Publication number
- CO5570656A2 CO5570656A2 CO05056576A CO05056576A CO5570656A2 CO 5570656 A2 CO5570656 A2 CO 5570656A2 CO 05056576 A CO05056576 A CO 05056576A CO 05056576 A CO05056576 A CO 05056576A CO 5570656 A2 CO5570656 A2 CO 5570656A2
- Authority
- CO
- Colombia
- Prior art keywords
- composition
- active substance
- environment
- controlled release
- weight
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1.- Un procedimiento para la liberación controlada de una sustancia activa a un entorno de uso, que comprende:preparar una composición de liberación controlada que comprende un núcleo que contiene sustancia activa y un recubrimiento polimérico asimétrico sobre él, en la que el polímero utilizado para formar dicho recubrimiento polimérico asimétrico es aquel que, cuando se ensaya mediante imbibición durante al menos 16 horas en una solución acuosa que comprende 0,5% en peso de grasa de la dieta, gana menos de aproximadamente un 15% en peso, y administrar dicha composición a dicho entorno de uso, comprendiendo dicho entorno de uso al menos aproximadamente un 0,5% en peso de grasa de la dieta.2.- Un procedimiento para la liberación controlada de una sustancia activa a un entorno de uso, que comprende:preparar una composición de liberación controlada que comprende un núcleo que contiene sustancia activa y un recubrimiento polimérico asimétrico sobre el mismo, en la que el tiempo para liberar un 50% de dicha sustancia activa desde dicha composición a dicho entorno de uso es al menos 0,5 veces, pero menos de 2,0 veces, el tiempo necesario para que dicha composición libere un 50% de dicha sustancia activa a un entorno de uso control que comprende menos de aproximadamente un 0,1 % de grasa de la dieta, y administrar dicha composición a dicho entorno de uso, comprendiendo dicho entorno de uso al menos aproximadamente un 0,5% en peso de grasa de la dieta.3.- Un procedimiento para la liberación controlada de una sustancia activa a un entorno de uso, que comprende:preparar una composición de liberación controlada que comprende un núcleo que contiene sustancia activa y un recubrimiento polimérico asimétrico sobre el mismo, en la que la cantidad de fármaco liberado de dicha composición en cualquier momento entre la 2ª y la 10a hora después de la introducción de dicha composición a dicho entorno de uso es al menos 0,5 veces, pero menos de 2,0 veces, la cantidad de dicho fármaco liberado en el mismo tiempo entre la 2a y la 10ª hora por dicha composición a un entorno de uso control que comprende menos de aproximadamente un 0,1% de grasa de la dieta, y administrar dicha composición a dicho entorno de uso, comprendiendo dicho entorno de uso al menos aproximadamente un 0,5% en peso de grasa de la dieta.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43286002P | 2002-12-11 | 2002-12-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO5570656A2 true CO5570656A2 (es) | 2005-10-31 |
Family
ID=32508002
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO05056576A CO5570656A2 (es) | 2002-12-11 | 2005-06-10 | Liberacin controlada de una sustancia activa a un entorno rico en grasa |
Country Status (18)
Country | Link |
---|---|
US (1) | US20040121015A1 (es) |
EP (1) | EP1572163A1 (es) |
JP (1) | JP2006510655A (es) |
KR (1) | KR20050088311A (es) |
CN (1) | CN1726012A (es) |
AR (1) | AR042340A1 (es) |
AU (1) | AU2003283688A1 (es) |
BR (1) | BR0317275A (es) |
CA (1) | CA2508722A1 (es) |
CO (1) | CO5570656A2 (es) |
MX (1) | MXPA05005812A (es) |
NO (1) | NO20053068L (es) |
NZ (1) | NZ539915A (es) |
PL (1) | PL377479A1 (es) |
RU (1) | RU2308263C2 (es) |
TW (1) | TWI257302B (es) |
WO (1) | WO2004052343A1 (es) |
ZA (1) | ZA200503812B (es) |
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US5567441A (en) * | 1995-03-24 | 1996-10-22 | Andrx Pharmaceuticals Inc. | Diltiazem controlled release formulation |
US5736159A (en) * | 1995-04-28 | 1998-04-07 | Andrx Pharmaceuticals, Inc. | Controlled release formulation for water insoluble drugs in which a passageway is formed in situ |
WO1998053802A1 (en) * | 1997-05-30 | 1998-12-03 | Laboratorios Phoenix U.S.A., Inc. | Multi-layered osmotic device |
US6245357B1 (en) * | 1998-03-06 | 2001-06-12 | Alza Corporation | Extended release dosage form |
US6136835A (en) * | 1999-05-17 | 2000-10-24 | The Procter & Gamble Company | Methods of treatment for viral infections |
US6352721B1 (en) * | 2000-01-14 | 2002-03-05 | Osmotica Corp. | Combined diffusion/osmotic pumping drug delivery system |
-
2003
- 2003-11-28 CN CNA2003801059820A patent/CN1726012A/zh active Pending
- 2003-11-28 BR BR0317275-9A patent/BR0317275A/pt not_active Withdrawn
- 2003-11-28 CA CA002508722A patent/CA2508722A1/en not_active Abandoned
- 2003-11-28 PL PL377479A patent/PL377479A1/pl not_active Application Discontinuation
- 2003-11-28 KR KR1020057010547A patent/KR20050088311A/ko not_active Application Discontinuation
- 2003-11-28 EP EP03775669A patent/EP1572163A1/en not_active Withdrawn
- 2003-11-28 WO PCT/IB2003/005629 patent/WO2004052343A1/en active Application Filing
- 2003-11-28 NZ NZ539915A patent/NZ539915A/en unknown
- 2003-11-28 AU AU2003283688A patent/AU2003283688A1/en not_active Abandoned
- 2003-11-28 RU RU2005118101/15A patent/RU2308263C2/ru active
- 2003-11-28 MX MXPA05005812A patent/MXPA05005812A/es unknown
- 2003-11-28 JP JP2004558241A patent/JP2006510655A/ja not_active Withdrawn
- 2003-12-03 US US10/727,217 patent/US20040121015A1/en not_active Abandoned
- 2003-12-09 AR ARP030104525A patent/AR042340A1/es unknown
- 2003-12-10 TW TW092134835A patent/TWI257302B/zh not_active IP Right Cessation
-
2005
- 2005-05-11 ZA ZA200503812A patent/ZA200503812B/en unknown
- 2005-06-10 CO CO05056576A patent/CO5570656A2/es not_active Application Discontinuation
- 2005-06-22 NO NO20053068A patent/NO20053068L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US20040121015A1 (en) | 2004-06-24 |
BR0317275A (pt) | 2005-11-08 |
AR042340A1 (es) | 2005-06-15 |
EP1572163A1 (en) | 2005-09-14 |
RU2005118101A (ru) | 2006-01-20 |
RU2308263C2 (ru) | 2007-10-20 |
CN1726012A (zh) | 2006-01-25 |
NZ539915A (en) | 2007-09-28 |
ZA200503812B (en) | 2006-07-26 |
AU2003283688A1 (en) | 2004-06-30 |
KR20050088311A (ko) | 2005-09-05 |
NO20053068D0 (no) | 2005-06-22 |
MXPA05005812A (es) | 2005-08-16 |
JP2006510655A (ja) | 2006-03-30 |
TW200425888A (en) | 2004-12-01 |
PL377479A1 (pl) | 2006-02-06 |
NO20053068L (no) | 2005-09-07 |
WO2004052343A1 (en) | 2004-06-24 |
CA2508722A1 (en) | 2004-06-24 |
TWI257302B (en) | 2006-07-01 |
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