CO4700470A1 - Derivados de n-[1,4-diazabiciclo[2.2.2] oct-2-il)metil]ben- zamida, su preparacion y su aplicacion en terapeutica - Google Patents
Derivados de n-[1,4-diazabiciclo[2.2.2] oct-2-il)metil]ben- zamida, su preparacion y su aplicacion en terapeuticaInfo
- Publication number
- CO4700470A1 CO4700470A1 CO96030428A CO96030428A CO4700470A1 CO 4700470 A1 CO4700470 A1 CO 4700470A1 CO 96030428 A CO96030428 A CO 96030428A CO 96030428 A CO96030428 A CO 96030428A CO 4700470 A1 CO4700470 A1 CO 4700470A1
- Authority
- CO
- Colombia
- Prior art keywords
- diazabiciclo
- benzamide
- therapeutics
- oct
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D245/00—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms
- C07D245/02—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Un compuesto, bajo la forma de enantiómero puro o de una mezclaenantiómeros, que responde a la fórmula general (I):en donde:R1 representa un grupo metoxi o ciclopropilmetoxi,R2 representa un átomo de hidrógeno, de cloro o de un bromo, o bien tambiénR1 y R2 forman juntos, y en este orden, un grupo de la fórmula -O-CH2 -O-, -O-(CH2 )2 , -O-(CH2 )2 -O- u -O-(CH2 )3 -O-, R3 representa un átomo de hidrógeno oun grupo amino, yR4 representa un átomo de hidrógeno, de cloro o de bromo, en estado de base libre o de sal de adición de ácido.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9506951A FR2735475B1 (fr) | 1995-06-13 | 1995-06-13 | Derives de n-((1,4-diazabicyclo(2.2.2)oct-2-yl)methyl) benzamide, leur preparation et leur application en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO4700470A1 true CO4700470A1 (es) | 1998-12-29 |
Family
ID=9479885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO96030428A CO4700470A1 (es) | 1995-06-13 | 1996-06-12 | Derivados de n-[1,4-diazabiciclo[2.2.2] oct-2-il)metil]ben- zamida, su preparacion y su aplicacion en terapeutica |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5663173A (es) |
| EP (1) | EP0748807A1 (es) |
| JP (1) | JPH09118680A (es) |
| KR (1) | KR970001335A (es) |
| CN (1) | CN1143644A (es) |
| AR (1) | AR004669A1 (es) |
| AU (1) | AU704388B2 (es) |
| CA (1) | CA2178849A1 (es) |
| CO (1) | CO4700470A1 (es) |
| CZ (1) | CZ171696A3 (es) |
| FR (1) | FR2735475B1 (es) |
| HU (1) | HUP9601620A3 (es) |
| IL (1) | IL118644A (es) |
| NO (1) | NO305251B1 (es) |
| NZ (1) | NZ286805A (es) |
| PL (1) | PL314745A1 (es) |
| SK (1) | SK75296A3 (es) |
| TW (1) | TW372238B (es) |
| ZA (1) | ZA964985B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2756564B1 (fr) * | 1996-12-04 | 2004-05-14 | Synthelabo | Derives d'acide quinoleine-8-carboxylique, leur preparation et leur application en therapeutique |
| FR2756563B1 (fr) * | 1996-12-04 | 1998-12-24 | Synthelabo | Derives de benzoate de 1,4-diazabicyclo[2.2.2]oct-2-yl- methyle, leur preparation et leur application en therapeutique |
| WO1999024393A1 (en) | 1997-11-07 | 1999-05-20 | Pharmacia & Upjohn Company | Process to produce oxazolidinones |
| EP1468685A3 (en) * | 1998-06-15 | 2004-12-15 | Sepracor Inc. | Use of optically pure (+)-norcisapride for treating apnea, bulimia and other disorders |
| CZ20004736A3 (cs) | 1998-06-15 | 2001-09-12 | Sepracor, Inc. | Farmaceutický prostředek |
| IL140118A0 (en) | 1998-06-15 | 2002-02-10 | Sepracor Inc | Use of optically pure (+) norcisapride for treating apnea, bulimia and other disorders |
| EP1464333A3 (en) * | 1998-06-15 | 2004-12-15 | Sepracor Inc. | Use of optically pure (-) norcisapride in the treatment of apnea, bulimia, and other disorders |
| US6362202B1 (en) | 1999-03-02 | 2002-03-26 | Sepracor Inc. | Methods and compositions using (−) norcisapride in combination with proton pump inhibitors or H2 receptor antagonists |
| US6353005B1 (en) | 1999-03-02 | 2002-03-05 | Sepracor, Inc. | Method and compositions using (+) norcisapride in combination with proton pump inhibitors or H2 receptor antagonist |
| EP1758583A2 (en) * | 2004-05-31 | 2007-03-07 | Ranbaxy Laboratories Limited | Arylpiperazine derivatives useful as adrenergic receptor antagonists |
| US8071605B2 (en) | 2008-12-12 | 2011-12-06 | Astrazeneca Ab | Piperidine compounds for use in the treatment of bacterial infections |
| JP5549847B2 (ja) * | 2009-11-16 | 2014-07-16 | 東ソー株式会社 | Ｎ−（２−アルコキシメチル）トリエチレンジアミン類の製造法 |
| GB201219820D0 (en) | 2012-11-05 | 2012-12-19 | Isis Innovation | Compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4888353A (en) * | 1986-02-28 | 1989-12-19 | Erbamont, Inc. | Carboxamides useful as antiemetic or antipsychotic agents |
| JP3294611B2 (ja) * | 1991-09-12 | 2002-06-24 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | ５−ｈｔ４レセプター・アンタゴニスト |
| TW282460B (es) * | 1993-12-28 | 1996-08-01 | Yamanouchi Pharma Co Ltd |
-
1995
- 1995-06-13 FR FR9506951A patent/FR2735475B1/fr not_active Expired - Fee Related
-
1996
- 1996-06-11 TW TW085106988A patent/TW372238B/zh active
- 1996-06-11 EP EP96401249A patent/EP0748807A1/fr not_active Withdrawn
- 1996-06-12 JP JP8150874A patent/JPH09118680A/ja active Pending
- 1996-06-12 NZ NZ286805A patent/NZ286805A/en unknown
- 1996-06-12 CZ CZ961716A patent/CZ171696A3/cs unknown
- 1996-06-12 PL PL96314745A patent/PL314745A1/xx unknown
- 1996-06-12 US US08/662,199 patent/US5663173A/en not_active Expired - Fee Related
- 1996-06-12 CO CO96030428A patent/CO4700470A1/es unknown
- 1996-06-12 NO NO962477A patent/NO305251B1/no not_active IP Right Cessation
- 1996-06-12 AR ARP960103118A patent/AR004669A1/es unknown
- 1996-06-12 CN CN96108818A patent/CN1143644A/zh active Pending
- 1996-06-12 ZA ZA964985A patent/ZA964985B/xx unknown
- 1996-06-12 AU AU55912/96A patent/AU704388B2/en not_active Ceased
- 1996-06-12 CA CA002178849A patent/CA2178849A1/en not_active Abandoned
- 1996-06-12 KR KR1019960020894A patent/KR970001335A/ko active IP Right Grant
- 1996-06-12 HU HU9601620A patent/HUP9601620A3/hu unknown
- 1996-06-12 IL IL11864496A patent/IL118644A/xx not_active IP Right Cessation
- 1996-06-12 SK SK752-96A patent/SK75296A3/sk unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW372238B (en) | 1999-10-21 |
| HUP9601620A2 (en) | 1997-01-28 |
| HU9601620D0 (en) | 1996-08-28 |
| FR2735475A1 (fr) | 1996-12-20 |
| IL118644A0 (en) | 1996-10-16 |
| IL118644A (en) | 2000-02-17 |
| JPH09118680A (ja) | 1997-05-06 |
| SK75296A3 (en) | 1997-05-07 |
| US5663173A (en) | 1997-09-02 |
| CA2178849A1 (en) | 1996-12-14 |
| NO962477D0 (no) | 1996-06-12 |
| PL314745A1 (en) | 1996-12-23 |
| ZA964985B (en) | 1997-01-23 |
| HUP9601620A3 (en) | 1998-07-28 |
| AU5591296A (en) | 1997-01-02 |
| NO962477L (no) | 1996-12-16 |
| NZ286805A (en) | 1998-03-25 |
| EP0748807A1 (fr) | 1996-12-18 |
| AR004669A1 (es) | 1999-03-10 |
| CN1143644A (zh) | 1997-02-26 |
| AU704388B2 (en) | 1999-04-22 |
| NO305251B1 (no) | 1999-04-26 |
| FR2735475B1 (fr) | 1997-07-11 |
| KR970001335A (ko) | 1997-01-24 |
| CZ171696A3 (en) | 1997-01-15 |
| MX9602306A (es) | 1997-10-31 |
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