CN215799611U - Combined magnetic frame for adenovirus separation - Google Patents

Combined magnetic frame for adenovirus separation Download PDF

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Publication number
CN215799611U
CN215799611U CN202122237871.3U CN202122237871U CN215799611U CN 215799611 U CN215799611 U CN 215799611U CN 202122237871 U CN202122237871 U CN 202122237871U CN 215799611 U CN215799611 U CN 215799611U
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China
Prior art keywords
clamping
grooves
top seat
adenovirus
fixedly connected
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CN202122237871.3U
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Chinese (zh)
Inventor
方先龙
顾锦法
张婷婷
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Shanghai Yuansong Biotechnology Co ltd
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Shanghai Yuansong Biotechnology Co ltd
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Abstract

The utility model discloses a combined magnetic frame for adenovirus separation, which relates to the technical field of virus purification and comprises a base, wherein the top of one end of the base is fixedly connected with a supporting column, the top end of the supporting column is fixedly connected with a top seat, one end of the top seat, which is far away from the supporting column, is provided with a clamping groove, and the side edge of the clamping groove is provided with a clamping mechanism; the clamping mechanism comprises a plurality of side grooves positioned on the side edges of the clamping grooves, the side grooves are communicated with the clamping grooves and positioned in the top seat, one ends, far away from the clamping grooves, of the side grooves are fixedly connected with compression springs, balls are arranged at the ends, close to the clamping grooves, of the side grooves, the diameters of the ends, close to the clamping grooves, of the side grooves are smaller than the diameters of the balls, and an opening is formed in the end, located at the clamping grooves, of the top seat.

Description

Combined magnetic frame for adenovirus separation
Technical Field
The utility model relates to the technical field of virus purification, in particular to a combined magnetic frame for adenovirus separation.
Background
The magnetic separation technology is a technology for separating biomacromolecules by using superparamagnetic beads. Due to the characteristics of convenience, rapidness, simple required equipment, high extraction efficiency and the like, and the advantages of being beneficial to keeping the sample properties, particularly the biological activity and the like, the technology is widely applied to the field of biological extraction, such as protein and enzyme immobilization, immunoassay, RNA and DNA pure extraction and purification, cell separation, drug carriers and the like. Compared with common separation methods such as precipitation, centrifugation, ion exchange and various chromatographic methods, the magnetic separation technology has the characteristics of convenience, rapidness, simple required equipment, high separation speed, high extraction efficiency and the like, and is favorable for maintaining the properties, especially the biological activity, of the sample. The magnetic separation process includes adding magnetic beads capable of combining with the sample to be separated into solution containing the sample to be separated, applying outer magnetic field to the solution through the magnetic separation rack after the magnetic beads are fully combined with the sample to be separated, and enriching the magnetic beads combined with the sample to be separated from the solution under the action of the outer magnetic field, so that the separation of the sample to be separated is realized.
The existing magnetic separation frame can only support a centrifuge tube generally, and the centrifuge tubes of different manufacturers cannot be effectively fixed due to different tube diameters. In the use, if a plurality of centrifuging tubes need overturn, then can make the centrifuging tube drop, it is very inconvenient to operate.
SUMMERY OF THE UTILITY MODEL
The present invention provides a combinable magnetic rack for adenovirus isolation that solves the problems set forth in the background above.
In order to achieve the purpose, the utility model provides the following technical scheme:
a combined magnetic frame for adenovirus separation comprises a base, wherein the top of one end of the base is fixedly connected with a supporting column, the top end of the supporting column is fixedly connected with a top seat, one end of the top seat, far away from the supporting column, is provided with a clamping groove, and the side edge of the clamping groove is provided with a clamping mechanism;
the clamping mechanism comprises a plurality of side grooves located on the sides of the clamping grooves, the side grooves are communicated with the clamping grooves and located in the top seat, one end, far away from the clamping grooves, of each side groove is fixedly connected with a compression spring, and balls are arranged at one ends, close to the clamping grooves, of the side grooves.
In a preferred embodiment of the present invention, a diameter of an end of the side groove near the holding groove is smaller than a diameter of the ball.
As a preferable technical scheme of the utility model, one end of the top seat, which is positioned at the clamping groove, is provided with an opening.
The utility model has the following advantages: the utility model can rapidly, conveniently and stably clamp the centrifugal tube by arranging the clamping mechanism, and can facilitate the adenovirus separation operation.
Drawings
FIG. 1 is a schematic diagram of a combinable magnetic frame for adenovirus isolation.
FIG. 2 is a cross-sectional view of the top mount in the combinable magnetic stand for adenovirus isolation.
In the figure: 1. a base; 2. a pillar; 3. a top seat; 4. a clamping groove; 5. a clamping mechanism; 6. a side groove; 7. a compression spring; 8. and a ball.
Detailed Description
The preferred embodiments of the present invention will be described in conjunction with the accompanying drawings, and it will be understood that they are described herein for the purpose of illustration and explanation and not limitation.
It should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience in describing the present invention and simplifying the description, but do not indicate or imply that the referred devices or elements must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention.
Example 1
Referring to fig. 1-2, a combined magnetic frame for adenovirus separation comprises a base 1, a pillar 2 is fixedly connected to the top of one end of the base 1, a top seat 3 is fixedly connected to the top of the pillar 2, a clamping groove 4 is formed in one end of the top seat 3 far away from the pillar 2, and a clamping mechanism 5 is arranged on the side of the clamping groove 4;
the clamping mechanism 5 comprises a plurality of side grooves 6 located on the sides of the clamping grooves 4, the side grooves 6 are communicated with the clamping grooves 4 and located in the top seat 3, one ends, far away from the clamping grooves 4, of the side grooves 6 are fixedly connected with compression springs 7, and balls 8 are arranged at one ends, close to the clamping grooves 4, of the side grooves 6.
In a preferred embodiment of the present invention, the diameter of the end of the side groove 6 near the holding groove 4 is smaller than the diameter of the ball 8.
As a preferred technical solution of the present invention, an opening is provided at one end of the top seat 3 located at the clamping groove 4.
In the implementation process of the centrifugal tube fixing device, the ball 8 and the compression spring 7 are in linkage action to tightly clamp the centrifugal tube when the centrifugal tube is inserted so as to stably fix the centrifugal tubes with different sizes.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that changes may be made in the embodiments and/or equivalents thereof without departing from the spirit and scope of the utility model. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (3)

1. A combined magnetic frame for adenovirus separation comprises a base and is characterized in that the top of one end of the base is fixedly connected with a supporting column, the top end of the supporting column is fixedly connected with a top seat, one end of the top seat, far away from the supporting column, is provided with a clamping groove, and the side edge of the clamping groove is provided with a clamping mechanism;
the clamping mechanism comprises a plurality of side grooves located on the sides of the clamping grooves, the side grooves are communicated with the clamping grooves and located in the top seat, one end, far away from the clamping grooves, of each side groove is fixedly connected with a compression spring, and balls are arranged at one ends, close to the clamping grooves, of the side grooves.
2. The combinable magnetic mount for adenovirus isolation of claim 1 wherein the end of the side groove proximate the clamping groove has a diameter less than the diameter of the ball bearing.
3. The combinable magnetic rack for adenovirus isolation of claim 1, wherein the top seat is provided with an opening at one end of the clamping groove.
CN202122237871.3U 2021-09-15 2021-09-15 Combined magnetic frame for adenovirus separation Active CN215799611U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202122237871.3U CN215799611U (en) 2021-09-15 2021-09-15 Combined magnetic frame for adenovirus separation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202122237871.3U CN215799611U (en) 2021-09-15 2021-09-15 Combined magnetic frame for adenovirus separation

Publications (1)

Publication Number Publication Date
CN215799611U true CN215799611U (en) 2022-02-11

Family

ID=80160843

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202122237871.3U Active CN215799611U (en) 2021-09-15 2021-09-15 Combined magnetic frame for adenovirus separation

Country Status (1)

Country Link
CN (1) CN215799611U (en)

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