CN221117399U

CN221117399U - Novel magnetic frame

Info

Publication number: CN221117399U
Application number: CN202322833509.1U
Authority: CN
Inventors: 王金月; 李永霞
Original assignee: Shanghai Lingjun Biotechnology Co ltd
Current assignee: Shanghai Lingjun Biotechnology Co ltd
Priority date: 2023-10-20
Filing date: 2023-10-20
Publication date: 2024-06-11
Anticipated expiration: 2033-10-20

Abstract

The utility model discloses a novel magnetic rack which is characterized by comprising a base (4), a supporting plate (3) and a first top plate (2); the supporting plate (3) is movably connected between the base (4) and the first top plate (2); a plurality of test tube holes (24) are formed in the first top plate (2); the supporting plate (3) is provided with a plurality of first assembly holes (31). According to the novel magnetic rack disclosed by the utility model, the test requirements of test tubes with different liquid amounts can be met by only selecting a proper supporting plate (3) to be assembled between the base (4) and the first top plate (2) according to the liquid amount of the reagent in the test tube, and in addition, when the magnet is damaged, the damaged magnet is replaced by the supporting plate (3), so that the test cost of an enterprise is reduced.

Description

Novel magnetic frame

Technical Field

The utility model belongs to the technical field of nucleic acid extraction, and particularly relates to a novel magnetic rack.

Background

The magnetic nanometer material is a novel functional material which relates to nanometer material science and bioscience, takes an iron oxide compound as an inner core, can be coated with various groups on the surface, can be used for carrying out rapid solid-liquid separation under the action of an externally applied magnetic field, and can be used for separating and purifying nucleic acid through hydrophobic action, hydrogen bonding action, electrostatic action and the like. With the vigorous development of the technologies such as gene diagnosis, transgenic food detection, personalized medicine and the like, the nucleic acid extraction technology using the nano magnetic beads as the carrier can efficiently, quickly and conveniently separate and purify nucleic acid from blood, animal tissues, food, pathogenic microorganisms, soil and other samples, and compared with the traditional separation methods such as extraction method, precipitation method, centrifugation method and the like, the advantage of the magnetic separation technology is more and more obvious. Is widely used in various fields such as clinical disease diagnosis, environmental microorganism detection, food safety detection, molecular biology research and the like. Thus, rapid and efficient isolation of high purity nucleic acids is an important prerequisite for various scientific studies in the field of modern molecular biology.

The basic steps of magnetic bead nucleic acid extraction and purification are cleavage-combination-washing-elution, and the magnetic rack is a main device for generating an external magnetic field in the whole process, and impurities such as protein and the like are removed by utilizing a buffer solution system under the action of the magnetic rack through solid-liquid separation, so that the nucleic acid is enriched and purified. Therefore, the practical applicability of magnetomotive force frames in practical nucleic acid extraction experiments has become an important focus of researchers.

The existing magnetic rack on the market is generally formed by a main body rack and a magnetic plate integrated structure, so that a single magnetic rack can only meet test tube testing of single liquid amount, the existing magnetic rack with the integrated structure can not meet the requirements of reagent systems of different liquid amounts, and once the magnetic plate is damaged, the service efficiency of the whole magnetic rack is affected.

Disclosure of utility model

The utility model aims to provide a novel magnetic frame.

The utility model provides a novel magnetic frame which comprises a base (4), a supporting plate (3) and a first top plate (2); the supporting plate (3) is movably connected between the base (4) and the first top plate (2); a plurality of test tube holes (24) are formed in the first top plate (2); the supporting plate (3) is provided with a plurality of first assembly holes (31).

Preferably, the bottom of the first top plate (2) is provided with a first groove (21) along the length direction; the top of the base (4) is provided with a second groove (42) along the length direction; two ends of the supporting plate (3) are respectively clamped in the first groove (21) and the second groove (42).

Preferably, the bottom openings of the first groove (21) and the second groove (42) are larger than the top opening.

Preferably, the top of the base (4) is also uniformly provided with a plurality of third grooves (41) along the length direction; each of the plurality of third grooves (41) is coaxially disposed with each of the plurality of test tube wells (24).

Preferably, the novel magnetic rack provided by the utility model further comprises a bin cover (1), wherein the bin cover (1) is arranged at the top of the first top plate (2); the bin cover (1) is formed by enclosing a first side plate (14), a front wall plate (13), a second side plate (12), a rear wall plate (11) and a second top plate (15) into a bin body structure with one open surface.

Preferably, a first hinge post (16) is arranged on both sides of the bottom of the rear wall plate (11); two ends close to the top of one side of the first top plate (2) are respectively provided with a first hinging seat (22); the first hinge post (16) comprises a first post (162) and two second posts (161) symmetrically arranged at two sides of the first post (162); the first hinge seat (22) comprises two first plate bodies (222); the centers of the two first plate bodies (222) are respectively provided with a first shaft hole (221) which is coaxially arranged; the first hinge columns (16) are arranged between the two first plate bodies (222), and the two second column bodies (161) are respectively inserted into the two first shaft holes (221).

Preferably, the inner side wall of the second top plate (15) is uniformly provided with a plurality of fourth grooves (151) along the length direction thereof.

Preferably, a first catch (131) is fitted close to the bottom of the front wall plate (13); one side of the first top plate (2) is provided with a second buckle (23) matched with the first buckle (131).

Compared with the prior art, the novel magnetic frame provided by the utility model has the advantages that:

1. The backup pad, base and first roof are detachable connection, can satisfy the requirement of different liquid measure reagent systems to in case the magnet takes place to damage, only need change corresponding magnet can, reduced the cost of enterprise.

2. Through the first roof of storehouse lid card box, can prevent to reverse the in-process centrifuging tube of mixing easily to drop to reagent loss or the risk of pollution have been reduced.

3. The test tube lid buckle is in the fourth recess, need not to shift one by one when carrying out multitube operation pipetting like this, in the in-process that liquid was removed, the pipette rifle also can not touch the magnetic bead or inhale the magnetic bead to the risk of sample loss has been reduced.

4. All buckles of test tube lid are in the fourth recess, therefore only need the lid to close the storehouse lid, can once only with test tube lid close to the test tube on, need not to cover the test tube one by one to experimental efficiency has been improved.

Drawings

FIG. 1 is a schematic view of a first state structure of a novel magnetic frame provided by the utility model;

FIG. 2 is a schematic diagram of a second state structure of the novel magnetic rack provided by the utility model;

FIG. 3 is a schematic structural view of a base according to an embodiment of the present utility model;

Fig. 4 is a schematic structural view of a first top plate according to an embodiment of the present utility model;

FIG. 5 is a schematic view of a partial structure of a first top plate according to an embodiment of the present utility model;

FIG. 6 is a schematic view of an assembled structure of a first hinge post and a first hinge base according to an embodiment of the present utility model;

Fig. 7 is a schematic structural view of a support plate according to an embodiment of the present utility model;

Fig. 8 is a schematic view of a first view structure of a bin cover according to an embodiment of the utility model;

FIG. 9 is a schematic view of a second view structure of a bin cover according to an embodiment of the utility model;

Fig. 10 is a schematic view of a first view structure of a test tube according to an embodiment of the present utility model.

Detailed Description

For the purpose of making the objects, technical solutions and advantages of the embodiments of the present utility model more apparent, the technical solutions of the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model, and it is apparent that the described embodiments are some embodiments of the present utility model, but not all embodiments of the present utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

As shown in fig. 1 to 10, the novel magnetic rack provided by the embodiment comprises a base 4, a supporting plate 3 and a first top plate 2; the supporting plate 3 is movably connected between the base 4 and the first top plate 2; the first top plate 2 is provided with a plurality of test tube holes 24; the support plate 3 is provided with a plurality of first assembly holes 31. It can be appreciated by those skilled in the art that the first assembly hole 31 is used for assembling a magnet, and the novel magnetic rack provided in this embodiment can meet the test requirements of test tubes with different liquid amounts by only selecting a proper support plate 3 to assemble between the base 4 and the first top plate 2 according to the liquid amount of the reagent in the test tube, in addition, when the magnet is damaged, only the damaged magnet is replaced from the support plate 3, so that the test cost of an enterprise is reduced.

Further, the bottom of the first top plate 2 is provided with a first groove 21 along the length direction thereof; the top of the base 4 is provided with a second groove 42 along the length direction; both ends of the supporting plate 3 are respectively clamped in the first groove 21 and the second groove 42. It will be appreciated by those skilled in the art that the two ends of the support plate 3 are respectively engaged in the first recess 21 and the second recess 42, so that a suitable support plate 3 can be selected according to the type of test tube before the experiment.

Further, the bottom openings of the first recess 21 and the second recess 42 are larger than the top openings. As will be appreciated by those skilled in the art, such a design allows the support plate 3 to be more securely clamped between the first top plate 2 and the base 4, preventing the support plate 3 from sliding out of the first recess 21 or the second recess 42.

Further, the top of the base 4 is also uniformly provided with a plurality of third grooves 41 along the length direction thereof; each of the plurality of third recesses 41 is coaxially disposed with each of the plurality of test tube holes 24. As will be appreciated by those skilled in the art, when the test tube is inserted into the test tube hole 24, the bottom of the test tube will be clamped in the third groove 41, so that the test tube can be further prevented from shaking, thereby improving the experimental efficiency.

Further, the novel magnetic rack provided by the embodiment further comprises a bin cover 1, wherein the bin cover 1 is arranged at the top of the first top plate 2; the bin cover 1 is enclosed by a first side plate 14, a front wall plate 13, a second side plate 12, a rear wall plate 11 and a second top plate 15 to form a bin body structure with one open surface. It will be appreciated by those skilled in the art that designing a cap 1 avoids the risk of dropping the tube during the inversion and mixing process, while providing for easier handling.

Further, a first hinge post 16 is provided on both sides of the bottom portion near the rear wall plate 11; two ends close to the top of one side of the first top plate 2 are respectively provided with a first hinging seat 22; the first hinge post 16 includes a first post 162 and two second posts 161 symmetrically disposed at both sides of the first post 162; the first hinge base 22 includes two first plates 222; the centers of the two first plate bodies 222 are respectively provided with a first shaft hole 221 which is coaxially arranged; the first hinge post 16 is disposed between the two first plates 222, and the two second posts 161 are respectively inserted into the two first shaft holes 221.

Further, the inner side wall of the second top plate 15 is uniformly provided with a plurality of fourth grooves 151 along the length direction thereof. It can be appreciated by those skilled in the art that after the test tube with the test tube cover is inserted into the test tube hole 24, the test tube cover can be buckled into the fourth groove 151, so that all test tubes can be covered and opened once through the cover bin cover 1, and meanwhile, the test tube cover is buckled into the fourth groove 151, so that the multi-tube liquid can be poured at the same time, and pollution and complexity caused by repeated suction and pipetting of the pipetting gun are avoided.

Further, a first catch 131 is fitted near the bottom of the front wall plate 13; a second buckle 23 matched with the first buckle 131 is arranged on one side of the first top plate 2. It will be appreciated by those skilled in the art that when the bin cover 1 is covered on the first top plate 2, the first buckle 131 can be buckled on the second buckle 23, so that the risk of throwing out the test tube when the bin cover 1 is opened in the process of shaking evenly upside down can be prevented, and the safety of the experiment is further improved. The first buckle 131 and the second buckle 23 are common technical means in the art, and will not be described herein.

Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present utility model, and are not limiting; although the utility model has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit and scope of the technical solutions of the embodiments of the present utility model.

Claims

1. The novel magnetic rack is characterized by comprising a base (4), a supporting plate (3) and a first top plate (2); the supporting plate (3) is movably connected between the base (4) and the first top plate (2); a plurality of test tube holes (24) are formed in the first top plate (2); the supporting plate (3) is provided with a plurality of first assembly holes (31);

The bottom of the first top plate (2) is provided with a first groove (21) along the length direction; the top of the base (4) is provided with a second groove (42) along the length direction; two ends of the supporting plate (3) are respectively clamped in the first groove (21) and the second groove (42).

2. A new magnetic stand according to claim 1, characterized in that the bottom openings of the first recess (21) and the second recess (42) are larger than the top opening.

3. The novel magnetic rack according to claim 2, wherein the top of the base (4) is further uniformly provided with a plurality of third grooves (41) along the length direction thereof; each of the plurality of third grooves (41) is coaxially disposed with each of the plurality of test tube wells (24).

4. A novel magnetic rack as claimed in claim 3, further comprising a bin cover (1), said bin cover (1) being disposed on top of said first top plate (2); the bin cover (1) is formed by enclosing a first side plate (14), a front wall plate (13), a second side plate (12), a rear wall plate (11) and a second top plate (15) into a bin body structure with one open surface.

5. A new magnetic stand according to claim 4, characterized in that the two sides near the bottom of the rear wall plate (11) are provided with first hinge posts (16); two ends close to the top of one side of the first top plate (2) are respectively provided with a first hinging seat (22); the first hinge post (16) comprises a first post (162) and two second posts (161) symmetrically arranged at two sides of the first post (162); the first hinge seat (22) comprises two first plate bodies (222); the centers of the two first plate bodies (222) are respectively provided with a first shaft hole (221) which is coaxially arranged; the first hinge columns (16) are arranged between the two first plate bodies (222), and the two second column bodies (161) are respectively inserted into the two first shaft holes (221).

6. The novel magnetic rack as claimed in claim 5, wherein the inner side wall of the second top plate (15) is uniformly provided with a plurality of fourth grooves (151) along the length direction thereof.

7. -Novel magnetic rack according to claim 6, characterised in that a first catch (131) is fitted near the bottom of the front wall plate (13); one side of the first top plate (2) is provided with a second buckle (23) matched with the first buckle (131).