CN209872968U

CN209872968U - Magnetic rack

Info

Publication number: CN209872968U
Application number: CN201920183070.3U
Authority: CN
Inventors: 章晶; 张长正; 叶真龙; 钱其军
Original assignee: Shanghai Bai Ze Medical Laboratory Co Ltd
Current assignee: Shanghai Bai Ze Medical Laboratory Co Ltd
Priority date: 2019-02-01
Filing date: 2019-02-01
Publication date: 2019-12-31
Anticipated expiration: 2029-02-01

Abstract

The utility model relates to a biological test technical field especially relates to a magnetic force frame, including dismantling a plurality of support bodies of connection in proper order, be equipped with the magnet that is used for placing the sample hole of reaction tube and is used for producing magnetic force on the support body, be equipped with between two adjacent support bodies and be used for dismantling the fixed part of connecting two support bodies. The utility model discloses a magnetic force frame includes a plurality of support bodies, all is equipped with sample hole and magnet on every support body, and the sample hole is used for placing the reaction tube, and the magnet can produce magnetic force, with the magnetic bead and the non-magnetic material separation in the reaction tube, reachs the purpose of purification to follow-up experiment carries out. Can dismantle the connection through the fixed part between the support body, select the support body number of connecting according to the experiment needs, can single use, also can link the equipment of several support bodies and use in the lump, many people of being convenient for use simultaneously, have improved the utilization efficiency, adapt to more experiment operations, and application scope enlarges. The frame body is detachably connected through the fixing part and is also convenient to carry.

Description

Magnetic rack

Technical Field

The utility model relates to a biological test device technical field especially relates to a magnetic frame.

Background

With the popularization of detection and treatment methods such as gene detection, personalized drug delivery, prenatal diagnosis and the like and the realization of automation in the biological field, magnetic separation technologies represented by a biomagnetic bead method are widely applied in the fields of cell separation, protein purification, immunology, microbiology detection and the like. The magnetic bead method is based on the same principle as the silica gel mold centrifugation method, and the superparamagnetic silica nano magnetic bead is prepared by improving and modifying the surface of superparamagnetic nano particles by using a nanotechnology. The magnetic beads can be specifically and efficiently combined with nucleic acid molecules. By using the superparamagnetism of the silicon oxide nano-microspheres, DNA and RNA can be separated from samples from different sources under the action of guanidine hydrochloride, guanidine isothiocyanate and the like and an external magnetic field. The magnetic separation technology can rapidly separate nucleic acid, protein and the like from other substances in cells, has the characteristics of automation, simple operation, short time consumption and the like, and has more and more obvious advantages compared with the traditional separation methods such as an extraction method, a precipitation method, a centrifugation method and the like.

The magnetic separation technology is to enrich and adsorb magnetic beads specifically bound to the surfaces of magnetic particles at a certain position under the action of a magnetic field, so that the magnetic beads are separated from other substances, and the purpose of purification is achieved. At present, the separation method of magnetic beads and other substances mainly comprises the steps of placing a reaction tube on a magnetic frame, arranging a magnetic rod at a fixed position of the magnetic frame, and separating the magnetic beads in the reaction tube through the magnetic force of the magnetic rod.

The existing magnetic frame is only provided with a plurality of sample holes on the whole frame body, the volume of the frame body is large, the utilization rate of the occupied space and the sample holes is low, and the magnetic frame is only provided with the magnetic frame of an independent 1.5ml EP pipe and the magnetic frame of a 0.2ml pipe, but the magnetic frames with different pipe diameters are often used in an experiment, and the magnetic frame for replacing the pipe diameters in the experiment can cause inconvenient use. And the existing magnetic frame with 0.2ml is 96 holes, so that the use is extremely inconvenient, and the hole diameter of the holes is small and the arrangement is tight due to the limited surface area of the frame body, so that the use efficiency is not high.

SUMMERY OF THE UTILITY MODEL

Technical problem to be solved

The to-be-solved technical problem of the utility model is that the current magnetic frame size is fixed, unable split and the sample hole is arranged closely, the not high problem of availability factor.

(II) technical scheme

In order to solve the technical problem, the utility model provides a magnetic force frame, including a plurality of support bodies that can dismantle the connection in proper order, be equipped with the magnet that is used for placing the sample hole of reaction tube and is used for producing magnetic force on the support body, adjacent two be equipped with between the support body and be used for dismantling and connect two the fixed part of support body.

The fixing part comprises a clamping groove and a buckle matched with the clamping groove.

The clamping groove and the buckle are respectively arranged on two sides of the rack body along the direction perpendicular to the axial direction of the sample hole.

Wherein, the draw-in groove with the buckle all is located the tip of the both sides of support body.

Wherein, the magnet is an electromagnetic rod which can be electrified to generate magnetism.

Wherein, every have two rows on every the support body sample hole and one row the magnet, one row the magnet sets up in two rows between the sample hole.

Wherein each two of the sample wells in each row of the sample wells corresponds to one of the magnets.

Wherein the two rows of sample wells comprise a row of first sample wells and a row of second sample wells, the first sample wells having a diameter greater than the diameter of the second sample wells.

Wherein each of the first sample wells in each of the rows of the first sample wells corresponds to one of the magnets, and each of the second sample wells in each of the rows of the second sample wells corresponds to one of the magnets.

(III) advantageous effects

The above technical scheme of the utility model has following advantage: the utility model discloses a magnetic force frame includes a plurality of support bodies, all is equipped with sample hole and magnet on every support body, and the sample hole is used for placing the reaction tube, and the magnet can produce magnetic force, with the magnetic bead and the non-magnetic material separation in the reaction tube, reachs the purpose of purification to follow-up experiment carries out. Can dismantle the connection through the fixed part between the support body, select the support body number of connecting according to the experiment needs, can single use, also can link the equipment of several support bodies and use in the lump, many people of being convenient for use simultaneously, have improved the utilization efficiency, adapt to more experiment operations, and application scope enlarges. The frame body is detachably connected through the fixing part and is also convenient to carry.

In addition to the technical problems addressed by the present invention, the technical features of the constituent technical solutions, and the advantages brought by the technical features of these technical solutions, which are described above, other technical features of the present invention and the advantages brought by these technical features will be further explained with reference to the accompanying drawings.

Drawings

Fig. 1 is a schematic structural diagram of a frame body of a magnetic frame according to an embodiment of the present invention;

fig. 2 is a schematic structural diagram of a plurality of frame bodies of a magnetic frame according to an embodiment of the present invention;

fig. 3 is a schematic structural view of a plurality of frame bodies of a second magnetic frame according to an embodiment of the present invention.

In the figure: 1: a frame body; 2: a sample well; 3: a magnet; 4: a fixed part; 21: a first sample aperture; 22: a second sample well; 41: a card slot; 42: and (5) buckling.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.

In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.

In the description of the present invention, unless otherwise specified, "plurality", and "plural" mean two or more, and "several", and "several groups" mean one or more.

Example one

As shown in fig. 1 and 2, the embodiment of the present invention provides a magnetic rack, which comprises a plurality of rack bodies 1 that are connected in sequence, wherein a sample hole 2 for placing a reaction tube and a magnet 3 for generating magnetic force are arranged on each rack body 1, and a fixing portion 4 for connecting two rack bodies 1 in a detachable manner is arranged between two adjacent rack bodies 1.

The utility model discloses a magnetic force frame includes a plurality of support bodies, all is equipped with sample hole and magnet on every support body, and the sample hole is used for placing the reaction tube, and the magnet can produce magnetic force, with the magnetic bead and the non-magnetic material separation in the reaction tube, reachs the purpose of purification to follow-up experiment carries out. Can dismantle the connection through the fixed part between the support body, select the support body number of connecting according to the experiment needs, can single use, also can link the equipment of several support bodies and use in the lump, many people of being convenient for use simultaneously, have improved the utilization efficiency, adapt to more experiment operations, and application scope enlarges. The frame body is detachably connected through the fixing part and is also convenient to carry.

The fixing portion 4 includes a slot 41 and a buckle 42 engaged with the slot 41. The fixed part is the cooperation of buckle and draw-in groove, sets up the buckle on the support body, then sets up complex buckle with it on another draw-in groove, inserts the buckle in the draw-in groove, realizes the connection of these two support bodies, directly withdraws from the separation that can realize two support bodies with the buckle in by the draw-in groove during the split. Simple structure, convenient operation, labour saving and time saving.

The clamping groove 41 and the buckle 42 are respectively disposed on two sides of the rack body 1 along a direction perpendicular to the axial direction of the sample hole 2. The support body is the cuboid in this embodiment, and the sample hole sets up along the high direction of cuboid, and the long side face of cuboid support body sets up the fixed part, and every support body all has buckle and draw-in groove, and a long side sets up the buckle, and another long side sets up the draw-in groove to both sides all can be connected with other support bodies.

Wherein, the slot 41 and the buckle 42 are both located at the end parts of the two sides of the frame body 1. The end part of the frame body is provided with a clamping groove and a buckle, so that the connection is guaranteed to be stable and firm to the maximum extent, and the frame is convenient and labor-saving to disassemble.

The magnet 3 is an electromagnetic rod which can be electrified to generate magnetism. The magnet is the electromagnetic bar in this embodiment, and when circular telegram to the electromagnetic bar, the electromagnetic bar can produce magnetic force, and magnetic force is with the intraductal magnetic bead separation of reaction, and when the electromagnetic bar outage, the support body only plays supporting role to the reaction tube through the sample pore, and the realization is to the control of experimentation through having or not of control magnetic force, operates more nimble science.

Wherein, each rack body 1 is provided with two rows of sample holes 2 and one row of magnets 3, and the one row of magnets 3 is arranged between the two rows of sample holes 2. Two rows of sample holes and one row of magnets are arranged on one frame body, the magnets are positioned between the two rows of sample holes, the magnetic force of one side surface can be provided for the two rows of reaction tubes for magnetic attraction, the experimental process can be independently completed by each frame body, and the frame bodies connected with each other can not interfere with each other in the experimental process.

Wherein each two sample wells 2 in each row of sample wells 2 correspond to one magnet 3. In this embodiment, the two rows of sample wells have the same aperture, and each two sample wells in each row correspond to one magnet, i.e., four sample wells surround one magnet.

Example two

As shown in fig. 3, the magnetic rack according to the second embodiment of the present invention is substantially the same as the first embodiment, except that the two rows of sample holes 2 include one row of first sample holes 21 and one row of second sample holes 22, and the diameter of the first sample holes 21 is larger than that of the second sample holes 22. The aperture of first sample hole is different with the aperture of second sample hole to the installation of the reaction tube of the different pipe diameters that uses in the same experiment need not to change different magnetic frame again, convenient to use, and is efficient.

Wherein each first sample well 21 in each row of first sample wells 21 corresponds to one magnet 3, and each two second sample wells 22 in each row of second sample wells 22 correspond to one magnet 3. In this embodiment, two second sample wells with smaller apertures and one first sample well with larger apertures are surrounded by one magnet.

To sum up, the utility model discloses a magnetic force frame includes a plurality of support bodies, all is equipped with sample hole and magnet on every support body, and the sample hole is used for placing the reaction tube, and the magnet can produce magnetic force, with the magnetic bead and the non-magnetic material separation in the reaction tube, reachs the purpose of purification to follow-up experiment carries out. Can dismantle the connection through the fixed part between the support body, select the support body number of connecting according to the experiment needs, can single use, also can link the equipment of several support bodies and use in the lump, many people of being convenient for use simultaneously, have improved the utilization efficiency, adapt to more experiment operations, and application scope enlarges. The frame body is detachably connected through the fixing part and is also convenient to carry.

Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it should be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the present invention in its corresponding aspects.

Claims

1. A magnetic rack, its characterized in that: including dismantling a plurality of support bodies of connection in proper order, be equipped with the sample hole that is used for placing the reaction tube on the support body and be used for producing the magnet of magnetic force, adjacent two be equipped with between the support body and be used for dismantling to connect two the fixed part of support body.

2. The magnetic rack of claim 1, wherein: the fixing part comprises a clamping groove and a buckle matched with the clamping groove.

3. The magnetic rack of claim 2, wherein: the clamping groove and the buckle are respectively arranged on two sides of the frame body along the direction perpendicular to the axial direction of the sample hole.

4. A magnetic frame as claimed in claim 3, wherein: the clamping groove and the buckle are located at the end parts of the two sides of the frame body.

5. The magnetic rack of claim 1, wherein: the magnet is an electromagnetic rod which can be electrified to generate magnetism.

6. The magnetic rack of claim 1, wherein: each rack body is provided with two rows of sample holes and one row of magnets, and the magnets in one row are arranged between the two rows of sample holes.

7. The magnetic rack of claim 6, wherein: one magnet for each two sample wells in each row of sample wells.

8. The magnetic rack of claim 6, wherein: the two rows of sample wells include a row of first sample wells and a row of second sample wells, the first sample wells having a diameter greater than the diameter of the second sample wells.

9. A magnetic frame as claimed in claim 8, wherein: one magnet for each first sample well in each row of the first sample wells, and one magnet for each two second sample wells in each row of the second sample wells.