CN220579263U - Multifunctional detachable magnetic rack - Google Patents
Multifunctional detachable magnetic rack Download PDFInfo
- Publication number
- CN220579263U CN220579263U CN202322168212.8U CN202322168212U CN220579263U CN 220579263 U CN220579263 U CN 220579263U CN 202322168212 U CN202322168212 U CN 202322168212U CN 220579263 U CN220579263 U CN 220579263U
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- China
- Prior art keywords
- base
- detachable magnetic
- slope
- support body
- magnetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 210000005056 cell body Anatomy 0.000 claims abstract description 8
- 229910001172 neodymium magnet Inorganic materials 0.000 claims description 4
- QJVKUMXDEUEQLH-UHFFFAOYSA-N [B].[Fe].[Nd] Chemical compound [B].[Fe].[Nd] QJVKUMXDEUEQLH-UHFFFAOYSA-N 0.000 claims description 3
- 239000011324 bead Substances 0.000 description 23
- 108020004707 nucleic acids Proteins 0.000 description 7
- 102000039446 nucleic acids Human genes 0.000 description 7
- 150000007523 nucleic acids Chemical class 0.000 description 7
- 238000000034 method Methods 0.000 description 6
- 238000000746 purification Methods 0.000 description 5
- 108091032973 (ribonucleotides)n+m Proteins 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 108020004999 messenger RNA Proteins 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 2
- 238000003776 cleavage reaction Methods 0.000 description 2
- 238000010828 elution Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000007017 scission Effects 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 238000010876 biochemical test Methods 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000002299 complementary DNA Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000006911 enzymatic reaction Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Substances [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- -1 iron ions Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000007886 magnetic bead extraction Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000009870 specific binding Effects 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model provides a multi-functional detachable magnetic force frame, the effectual magnetic force frame function singleness of having solved, complex operation scheduling problem, it includes the base, is fixed with the support body on the base, both sides evenly are equipped with a plurality of cell bodies around the support body, installs the magnet of slope placement in the cell body, and the support body upper end is fixed with the workstation, and both sides sliding connection has a plurality of cardboard around the workstation, is equipped with the through-hole of slope on the cardboard, is equipped with the spacing groove that corresponds with the through-hole slope on the base.
Description
Technical Field
The utility model belongs to the technical field of biochemical test equipment, and particularly relates to a multifunctional detachable magnetic rack.
Background
At present, the most common method for purifying nucleic acid is a magnetic bead extraction method with the highest purification degree, and the DNA purification magnetic bead method mainly utilizes magnetic beads to adsorb DNA so as to separate other substances in cells such as DNA, protein and the like; the RNA purification magnetic beads can also be used for purifying and recovering RNA, and can stably, efficiently and conveniently purify RNA or cDNA from a common enzyme reaction system; mRNA magnetic bead separation techniques can also separate mRNA from other forms of RNA to obtain purified mRNA. The magnetic beads are magnetic substances capable of adsorbing DNA, and the inner core of the magnetic beads is iron ions which can be adsorbed on the magnet under the action of a magnetic field. A magnetic stand is a device that provides magnetic force of a magnetic field. The magnetic bead core is carboxylated, has carboxyl group and can be combined with DNA under specific ion condition. After the combination, the magnetic beads and DNA combination body move to the periphery of the magnet under the action of an external magnetic field, so that other redundant liquid can be conveniently removed, and at the moment, all impurities which cannot be combined with the magnetic beads are removed together with the aqueous solution. Then, under the condition of elution, the DNA is separated from the magnetic beads, dissolved in water, and the DNA-dissolved solution is transferred to obtain a purified DNA sample. The magnetic bead method for extracting nucleic acid can be generally divided into four steps: cleavage-binding-washing-eluting, i.e.sample cleavage-specific binding of nucleic acids to magnetic beads-washing of magnetic beads with nucleic acid conjugates-elution of nucleic acids from magnetic beads. In the magnetic bead method, first the magnetic beads are mixed with the sample in an appropriate ratio in an EP tube. The magnetic beads can be combined with target molecules in the sample within a few minutes. And then placing the EP tube into a magnetic frame, adsorbing target molecules or cells combined with the magnetic beads on the tube wall under the action of magnetic force, and discarding the supernatant to obtain the purified target molecules. The magnetic force frame provides magnetic force, fixes the centrifuging tube, can be fast with magnetic bead combination sample absorption to the pipe wall, realizes separation and purification.
Most of the magnetic force frames are designed to be equal in width up and down, and although the structure can meet the experiment requirement, the structure cannot provide convenience for the nucleic acid extraction operation, round magnets with low strength are adopted, the magnetic field distribution is strange, the magnetic beads cannot be effectively polymerized, the magnetic force is weak, the service life of the magnets is short, and the magnets can be demagnetized after being used for a period of time. The pore plate aperture is single, only can use one type of EP pipe, when extracting the nucleic acid of different volume, needs to use different EP pipes, just needs to purchase a plurality of magnetic force frames, just can satisfy the experiment demand, complex operation, with high costs.
Disclosure of Invention
Aiming at the situation, the utility model aims to overcome the defects of the prior art and provide the multifunctional detachable magnetic frame, which effectively solves the problems of single function, complex operation and the like of the magnetic frame.
The technical scheme that it solved is, including the base, be fixed with the support body on the base, both sides evenly are equipped with a plurality of cell bodies around the support body, install the magnet that the slope was placed in the cell body, and the support body upper end is fixed with the workstation, and both sides sliding connection has a plurality of cardboard around the workstation, is equipped with the through-hole of slope on the cardboard, is equipped with the spacing groove that corresponds with the through-hole slope on the base.
Preferably, the magnet is an N52 neodymium iron boron permanent magnet.
Preferably, the clamping plate is fixed with sliding grooves on two sides, sliding blocks matched with the sliding grooves are arranged in the workbench, and the sliding grooves slide back and forth along the sliding blocks.
Preferably, the left end and the right end of the frame body are provided with buckles.
Preferably, the frame body is of a trapezoid structure.
Preferably, the width of the base is larger than the width of the workbench, and the length of the base is the same as the length of the workbench.
Compared with the traditional equipment, the utility model has the following advantages: 1) The sliding block is matched with the sliding groove, so that the clamping plate is conveniently detached in the workbench in a drawing and inserting mode; 2) The clamping plates used by different EP pipes are matched with the same base, and when in use, different through holes are selected according to the sizes of the different EP pipes, so that the corresponding clamping plates are detached and replaced, the functions are complete, the operation is convenient, and the cost is low; 3) Concave-convex buckles are designed at two ends of the frame body so as to disassemble and assemble the magnetic frame.
Drawings
Fig. 1 is a schematic diagram of a perspective structure diagram of the present utility model.
Fig. 2 is a schematic diagram of a second perspective structure of the present utility model.
FIG. 3 is a schematic view of an assembled three-dimensional structure of two magnetic frames according to the present utility model.
Detailed Description
The following describes the embodiments of the present utility model in further detail with reference to the drawings.
Given by fig. 1 to 3, a multi-functional detachable magnetic force frame, including base 1, be fixed with support body 2 on the base 1, both sides evenly are equipped with a plurality of cell bodies around the support body 2, installs the magnet 3 of slope placement in the cell body, and support body 2 upper end is fixed with workstation 4, and both sides sliding connection has a plurality of cardboard 5 around the workstation 4, is equipped with the through-hole 6 of slope on the cardboard 5, is equipped with the spacing groove 7 that corresponds with the through-hole 6 slope on the base 1.
The magnet 3 adopts an N52 neodymium iron boron permanent magnet.
The two sides of the clamping plate 5 are fixedly provided with sliding grooves 8, sliding blocks 9 matched with the sliding grooves 8 are arranged in the workbench 4, and the sliding grooves 8 slide back and forth along the sliding blocks 9.
The left end and the right end of the frame body 2 are provided with buckles 10.
The frame body 2 is of a trapezoid structure.
The width of the base 1 is larger than that of the workbench 4, and the length of the base 1 is the same as that of the workbench 4.
When the utility model is used, the terms of front, back, left, right, up, down and the like indicate azimuth or position relation by taking a front view as a reference, an EP pipe is placed in the through hole 6, the limit groove 7 plays a role in limiting and supporting the lower end of the EP pipe, the magnet 3 adopts an N52 NdFeB permanent magnet, the magnet is obliquely placed, the magnetic field strength is high, the magnetic beads can be efficiently gathered, the magnetic beads form single linear arrangement in the magnetic field, the magnetic beads can be more concentrated in distribution, and meanwhile, the magnet 3 adopts a detachable design, thereby being convenient for replacement;
the width of the base 1 is larger than that of the workbench 4, the length of the base 1 is the same as that of the workbench 4, the frame body 2 is of a trapezoid structure, the base 1, the frame body 2 and the workbench 4 form an I-shaped structure with narrow upper part and wide lower part, an EP pipe can be obliquely placed, and a pipette is not easy to touch magnetic beads when the pipette is used for operation;
through the cooperation of the sliding groove 8 and the sliding block 9, the drawing-inserting type disassembly of the clamping plate 5 is realized, through experimental verification, the drawing-inserting type disassembly can be clamped, the experiment cannot be influenced in the experimental process, the EP pipes with different calibers can be adapted through replacing the clamping plates 5 with the through holes 6 with different calibers, the requirement that one magnetic frame is applied to EP with different types of specifications is met, the magnetic frame does not need to be replaced frequently, the operation is simple, and the cost is low;
the both ends are equipped with buckle 10 about support body 2, just so can assemble a big magnetic force frame with two support bodies 2 each other, compare in other products, when using a plurality of different EP pipes to draw, need change different magnetic force frames, use the big magnetic force frame of our such concatenation not more convenient, a plurality of magnetic force frames are in the same place, can satisfy the demand of using a plurality of EP pipes (16, 24) purification simultaneously.
The present embodiment is not limited in any way by the shape, material, structure, etc. of the present utility model, and any simple modification, equivalent variation and modification made to the above embodiments according to the technical substance of the present utility model are all included in the scope of protection of the technical solution of the present utility model.
Claims (6)
1. The utility model provides a multi-functional detachable magnetic force frame, a serial communication port, including base (1), be fixed with support body (2) on base (1), both sides evenly are equipped with a plurality of cell bodies around support body (2), install magnet (3) of slope placing in the cell body, support body (2) upper end is fixed with workstation (4), both sides sliding connection has a plurality of cardboard (5) around workstation (4), be equipped with through-hole (6) of slope on cardboard (5), be equipped with spacing groove (7) corresponding with the through-hole (6) slope on base (1).
2. The multifunctional detachable magnetic rack according to claim 1, wherein the magnet (3) is an N52 neodymium iron boron permanent magnet.
3. The multifunctional detachable magnetic rack according to claim 1, wherein sliding grooves (8) are fixed on two sides of the clamping plate (5), sliding blocks (9) matched with the sliding grooves (8) are arranged in the workbench (4), and the sliding grooves (8) slide back and forth along the sliding blocks (9).
4. The multifunctional detachable magnetic rack according to claim 1, wherein the left end and the right end of the rack body (2) are provided with buckles (10).
5. The multifunctional detachable magnetic rack according to claim 1, wherein the rack body (2) is of a trapezoid structure.
6. The multifunctional detachable magnetic rack according to claim 1, wherein the width of the base (1) is larger than the width of the workbench (4), and the length of the base (1) is the same as the length of the workbench (4).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322168212.8U CN220579263U (en) | 2023-08-11 | 2023-08-11 | Multifunctional detachable magnetic rack |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322168212.8U CN220579263U (en) | 2023-08-11 | 2023-08-11 | Multifunctional detachable magnetic rack |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220579263U true CN220579263U (en) | 2024-03-12 |
Family
ID=90108344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202322168212.8U Active CN220579263U (en) | 2023-08-11 | 2023-08-11 | Multifunctional detachable magnetic rack |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220579263U (en) |
-
2023
- 2023-08-11 CN CN202322168212.8U patent/CN220579263U/en active Active
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