CN212813855U - Multifunctional program cooling box - Google Patents

Multifunctional program cooling box Download PDF

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Publication number
CN212813855U
CN212813855U CN202021083882.XU CN202021083882U CN212813855U CN 212813855 U CN212813855 U CN 212813855U CN 202021083882 U CN202021083882 U CN 202021083882U CN 212813855 U CN212813855 U CN 212813855U
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China
Prior art keywords
storage tank
box body
carrier
functional
cooling cartridge
Prior art date
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Active
Application number
CN202021083882.XU
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Chinese (zh)
Inventor
陈学东
钟桂强
胡隽源
刘沐芸
梁晓
苏华莹
张芬
王清芳
钟振忠
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Shenzhen Beike Bio Technology Co ltd
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Shenzhen Beike Bio Technology Co ltd
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Priority to CN202021083882.XU priority Critical patent/CN212813855U/en
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Abstract

The utility model provides a multi-functional procedure cooling box, including box body, top cap, carrier and metal block, the box body is equipped with first storage tank and second storage tank, the second storage tank sets up in the tank bottom of first storage tank, the metal block set up in the second storage tank, the carrier set up in the first storage tank, the carrier is equipped with hole groove array and draw-in groove array, the top cap lid fits the box body, the top cap is equipped with the bleeder vent. The beneficial effects of the utility model reside in that: the utility model provides a good, rational in infrastructure, safe and reliable's procedure cooling box of thermal stability, can hold the cryopreserved sample of multiple different specifications and carry out the procedure cooling, when effectively having reduced the procedure cooling cost, also reduced the risk that operating personnel operated in low temperature environment.

Description

Multifunctional program cooling box
Technical Field
The utility model relates to the technical field of low-temperature medical equipment, in particular to a multifunctional program cooling box.
Background
Cryopreservation refers to a technique for storing biological samples at low temperature (e.g., liquid nitrogen, ultra-low temperature refrigerator). Scientists have long demonstrated that biological cell samples can be stored in low temperature environments for long periods of time. However, directly placing the cells in a low-temperature environment can cause damage to the cells, such as ice crystals or solutes, and the damage is irreversible and can affect the activity of the cells after recovery. Scientists have found that adding cryoprotectants to cryopreserved samples, when stored directly in a low temperature environment, can reduce irreversible damage to cells from the low temperature environment, but does not achieve the desired effect. Further research shows that the programmed cooling of the cell sample added with the cryoprotectant can obviously reduce the damage of ice crystals or solute and improve the recovery survival rate of cells.
At present, an isopropanol program cooling box or a program cooling instrument is most commonly used for carrying out program cooling on a frozen sample, but isopropanol belongs to a toxic solvent and is extremely volatile, so that the environment is polluted and the personal safety of experimenters is threatened after long-term use; the program cooling instrument is expensive, and has a great risk to the personal safety of experimenters due to the characteristics of volatile liquid nitrogen and extremely low temperature.
Therefore, there is a need for innovations in the prior art.
SUMMERY OF THE UTILITY MODEL
The utility model discloses the technical problem that will solve is: the utility model provides a good, the rational in infrastructure of thermal stability just can hold the procedure cooling box of multiple specification cryopreserved sample.
In order to solve the technical problem, the utility model discloses a technical scheme be: the utility model provides a multi-functional procedure cooling box, includes box body, top cap, carrier and metal block, the box body is equipped with first storage tank and second storage tank, the second storage tank sets up in the tank bottom of first storage tank, the metal block set up in the second storage tank, the carrier set up in the first storage tank, the carrier is equipped with hole groove array and draw-in groove array, the top cap lid fits the box body, the top cap is equipped with the bleeder vent.
Further, the hole and groove array comprises at least two rows of hole and grooves, and each row of hole and groove comprises at least two hole and grooves.
Further, the distance between two adjacent hole grooves is at least 3 mm.
Further, the distance between two adjacent rows of hole grooves is at least 3 mm.
Further, the card slot array comprises at least two card slots arranged side by side.
Further, the distance between two adjacent rows of clamping grooves is at least 3 mm.
Further, the box body is provided with a protrusion, and the top cover is provided with a groove corresponding to the protrusion.
Furthermore, the aperture of the air holes is 8-12 mm.
Furthermore, the box body and the top cover are both made of high-insulation cross-linked closed-cell polyethylene foam, and the carrier is made of high-insulation cross-linked closed-cell polyethylene.
Further, the metal block is a solid alloy hot core.
The beneficial effects of the utility model reside in that: the utility model provides a good, rational in infrastructure, safe and reliable's procedure cooling box of thermal stability, can hold the cryopreserved sample of multiple different specifications and carry out the procedure cooling, when effectively having reduced the procedure cooling cost, also reduced the risk that operating personnel operated in low temperature environment.
Drawings
The specific structure of the present invention is detailed below with reference to the accompanying drawings:
fig. 1 is a schematic diagram of the explosion structure of the present invention;
10-a box body; 11-a first receiving groove; 12-a bump; 13-a metal block;
20-a top cover; 21-air holes;
30-a carrier; 31-hole slots; 32-card slot.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
It should be noted that the description of the invention referring to "first", "second", etc. is for descriptive purposes only and is not to be construed as indicating or implying relative importance or implying any number of indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In addition, the technical solutions in the embodiments may be combined with each other, but it must be based on the realization of those skilled in the art, and when the technical solutions are contradictory or cannot be realized, the combination of the technical solutions should not be considered to exist, and is not within the protection scope of the present invention.
Example 1
Referring to fig. 1, a multifunctional program cooling box includes a box body 10, a top cover 20, a carrier 30 and a metal block 13, wherein the box body 10 has a first receiving slot 11 and a second receiving slot, the second receiving slot is disposed at the bottom of the first receiving slot 11, the metal block 13 is disposed in the second receiving slot, the carrier 30 is disposed in the first receiving slot 11, the carrier 30 has a slot array and a slot array, the top cover 20 covers the box body 10, and the top cover 20 has air holes 21.
In this embodiment, an air hole is formed above the top cover by mechanical drilling, the metal block is then placed in the second receiving groove of the box body, the carrier is then placed in the first receiving groove of the box body, wherein the opening area of the second receiving groove is smaller than the opening area of the first receiving groove, and finally the top cover is covered on the box body, thereby obtaining a prism-shaped closed container.
Because the top cover is provided with the air holes, the interior of the box is communicated with the outside all the time, no pressure difference is formed between the interior and the exterior of the box body, and the opening and the closing of the box are facilitated.
Be equipped with hole groove array and draw-in groove array on the carrier, can place the freezing of multiple specification and deposit the pipe or freeze and deposit the box, and freeze and deposit and can not contact each other between the box, be favorable to thermal volatilizing.
Wherein, the length of metal block is 150mm, and the width is 110mm, and highly is 10mm, and the size of second storage tank and the size adaptation of metal block.
From the above description, the beneficial effects of the present invention are: the utility model provides a good, rational in infrastructure, safe and reliable's procedure cooling box of thermal stability, can hold the cryopreserved sample of multiple different specifications and carry out the procedure cooling, when effectively having reduced the procedure cooling cost, also reduced the risk that operating personnel operated in low temperature environment.
Example 2
On the basis of embodiment 1, the hole-groove array comprises at least two rows of hole grooves, and each row of hole grooves comprises at least two hole grooves 31.
In the embodiment, the object carrier is provided with two rows of square hole grooves, the side length of each hole groove is 12mm, the depth of each hole groove is 50mm, and the arrangement of the hole grooves can effectively prevent the freezing storage pipes from inclining.
Example 3
On the basis of embodiment 2, the distance between two adjacent hole grooves 31 is at least 3 mm.
In this embodiment, can guarantee to place the freezing pipe among the adjacent hole groove and can not contact each other, be favorable to thermal volatilization.
Example 4
On the basis of embodiment 3, the distance between two adjacent rows of the hole grooves 31 is at least 3 mm.
In this embodiment, can guarantee to place the freezing pipe among two adjacent rows of hole grooves and can not contact each other, be favorable to thermal volatilization.
Example 5
On the basis of embodiment 4, the card slot array includes at least two card slots 32 arranged side by side.
In this embodiment, the carrier is provided with six rectangular slots, each slot is 160mm long, each slot is 11mm wide and 50mm deep, and can conveniently store freezing storage boxes or 50ml freezing storage bags.
Example 6
On the basis of embodiment 5, the distance between two adjacent rows of card slots 32 is at least 3 mm.
In this embodiment, can guarantee to place the cryopreserved box or cryopreserved bag among two adjacent rows of draw-in grooves and can not contact each other, be favorable to thermal volatilizing.
Example 7
On the basis of any one of the above embodiments, the box body 10 is provided with a protrusion 12, and the top cover 20 is provided with a groove corresponding to the protrusion 12.
In this embodiment, the box body is equipped with the arch, the top cap corresponds the arch is equipped with the recess of adaptation, makes box body and top cap be the interlock form when the lid closes, can guarantee the sealing performance of box body and top cap well.
Example 8
On the basis of the embodiment 7, the aperture of the air holes 21 is 8-12 mm.
In the embodiment, when the aperture of the air hole is 8-12mm, the pressure difference between the inside and the outside of the box body can be ensured without influencing the program cooling, so that the opening and the closing of the box are facilitated.
Preferably, the pore diameter of the air holes is 10 mm.
Example 9
In example 8, the box body 10 and the top cover 20 are made of high-insulation cross-linked closed-cell polyethylene foam, and the rack 30 is made of high-insulation cross-linked closed-cell polyethylene.
In the embodiment, the cross-linked modified polyethylene foam can obviously improve the environmental stress cracking resistance and the chemical corrosion resistance, and is not easy to crack due to overlarge external force, and can not crack due to chemical corrosion, so that the safety of the sample to be frozen is greatly protected.
In addition, the polyethylene foam modified by crosslinking has excellent thermal stability, and the metal block at the bottom in the box body can finely adjust and balance a freezing curve, so that a freezing rate of-1 ℃/min can be provided for programmed cooling.
Example 10
On the basis of the embodiment 9, the metal block 13 is a solid alloy hot core.
In the embodiment, the metal block of the solid alloy hot core is placed in the box body, so that the freezing curve can be finely adjusted and balanced, the freezing speed of-1 ℃/min can be provided for program cooling, the freezing process is more stable and controllable, the damage of ice crystals or solutes can be obviously reduced, and the recovery survival rate of cells is improved.
The above only is the embodiment of the present invention, not limiting the patent scope of the present invention, all the equivalent structures or equivalent processes that are used in the specification and the attached drawings or directly or indirectly applied to other related technical fields are included in the patent protection scope of the present invention.

Claims (10)

1. The utility model provides a multi-functional procedure cooling box which characterized in that: including box body, top cap, carrier and metal block, the box body is equipped with first storage tank and second storage tank, the second storage tank sets up in the tank bottom of first storage tank, the metal block set up in the second storage tank, the carrier set up in the first storage tank, the carrier is equipped with hole groove array and draw-in groove array, the top cap lid fits the box body, the top cap is equipped with the bleeder vent.
2. The multi-functional procedural cooling cartridge of claim 1, wherein: the hole groove array comprises at least two rows of hole grooves, and each row of hole grooves comprises at least two hole grooves.
3. The multi-functional procedural cooling cartridge of claim 2, wherein: the distance between two adjacent hole grooves is at least 3 mm.
4. The multi-functional procedural cooling cartridge of claim 3, wherein: the distance between two adjacent rows of hole grooves is at least 3 mm.
5. The multi-functional procedural cooling cartridge of claim 4, wherein: the card slot array comprises at least two card slots arranged side by side.
6. The multi-functional procedural cooling cartridge of claim 5, wherein: the distance between two adjacent rows of clamping grooves is at least 3 mm.
7. The multi-functional procedural cooling cartridge of any one of claims 1-6, wherein: the box body is provided with a bulge, and the top cover is provided with a groove corresponding to the bulge.
8. The multi-functional procedural cooling cartridge of claim 7, wherein: the aperture of the air holes is 8-12 mm.
9. The multi-functional procedural cooling cartridge of claim 8, wherein: the box body and the top cover are made of high-insulation cross-linked closed-cell polyethylene foam, and the carrier is made of high-insulation cross-linked closed-cell polyethylene.
10. The multi-functional procedural cooling cartridge of claim 9, wherein: the metal block is a solid alloy hot core.
CN202021083882.XU 2020-06-12 2020-06-12 Multifunctional program cooling box Active CN212813855U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202021083882.XU CN212813855U (en) 2020-06-12 2020-06-12 Multifunctional program cooling box

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202021083882.XU CN212813855U (en) 2020-06-12 2020-06-12 Multifunctional program cooling box

Publications (1)

Publication Number Publication Date
CN212813855U true CN212813855U (en) 2021-03-30

Family

ID=75172273

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202021083882.XU Active CN212813855U (en) 2020-06-12 2020-06-12 Multifunctional program cooling box

Country Status (1)

Country Link
CN (1) CN212813855U (en)

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Legal Events

Date Code Title Description
GR01 Patent grant
GR01 Patent grant
EE01 Entry into force of recordation of patent licensing contract
EE01 Entry into force of recordation of patent licensing contract

Assignee: Harbin Beike Health Technology Co.,Ltd.

Assignor: SHENZHEN BEIKE BIO-TECHNOLOGY Co.,Ltd.

Contract record no.: X2023440020002

Denomination of utility model: Multi-function program cooling box

Granted publication date: 20210330

License type: Common License

Record date: 20230116